39results about "Immune system evaluation" patented technology

A surgical computing system may receive usage data associated with movement of a surgical instrument and user inputs to the surgical instrument. The surgical computing system may receive motion and / or biomarker sensor data from sensing systems applied to the operator of the surgical instrument. The surgical computing system may determine, based on at least one of the usage data and / or the sensor data, a control feature for implementation by the surgical instrument. The surgical computing system may communicate the determined control feature(s) to the surgical instrument. The surgical instrument may modify its operation based on the control features.

A surgical computing system may receive measurement data from at least one sensing system. The measurement data may be associated with a set of patient biomarkers of a patient. A surgical computing system may obtain a set of patient parameters associated with the patient. A surgical computing system may generate vectorized patient data based on at least the measurement data and a set of patient-specific parameters. A surgical computing system may use a predictive model to predict an occurrence of a prolonged air leak (PAL) based at least on the vectorized patient data. A surgical computing system may generate a set of recommendations for preventing the PAL.

A system and method for collecting symptomatic data to screen for a targeted disease. Testing hardware incorporates a plurality of testing units with corresponding indicators that can be altered to indicate whether a symptom is present or not. The resulting data from the testing use can then be analyzed to determine the likelihood of presence of a disease.

A system and method for collecting symptomatic data to screen for a targeted disease. Testing hardware incorporates a plurality of testing units with corresponding indicators that can be altered to indicate whether a symptom is present or not. The resulting data from the testing use can then be analyzed to determine the likelihood of presence of a disease.

A lymphatic system examination device includes: a main body portion configured to position a lower body of the subject in an imaging region; an illumination unit configured to irradiate the lower body with excitation light; an imaging unit configured to detect fluorescence emitted from the lower body; a display unit configured to display the fluorescent image of the lower body; and a control unit configured to control the illumination unit, the imaging unit, and the display unit. The control unit controls at least one of the illumination unit and the imaging unit so as to change at least one of the light emission time of the illumination unit and the exposure time of the imaging unit, thereby generating a plurality of types of fluorescent images as the fluorescent image and controlling the display unit so that the plurality of types of fluorescent images are displayed side by side.

The invention relates to a system for measuring a level of a subject's immune activity (10), the system comprising: - an exhaled air sensor (20), - a device for measuring exhaled air (30), - computation means (40) suitable for determining data relating to the air exhaled by the subject from the measurements carried out by the device (30), - a memory (60) suitable for storing the measurements performed by the device (30) and / or the data calculated by the means (40), and the subject's personal data, - a computation means (70) suitable for determining a level of the subject's immune activity on the basis of at least one item of exhaled air data, generated in real time by the means (40) and / or stored in the memory (60), - a communication and management interface (80) suitable for presenting said level of the subject's immune activity and / or sub-scores of immunological activity, inflammatory activity, digestive inflammation and / or pulmonary inflammation.

A lymphatic system examination device includes a main body portion including a placement portion on which a subject stands, and configured to position a lower body of a subject in an imaging region, an illumination unit configured to irradiate the lower body with excitation light; and an imaging unit configured to detect fluorescence emitted from the lower body. The illumination unit and the imaging unit are arranged on one side in a first horizontal direction with respect to the imaging region. The main body portion further includes a restricting portion. The restricting portion is disposed along the upper end portion of the imaging region and restricts movement of the subject to one side in the first horizontal direction.

A system for measuring the level of immune activity (10) of a subject comprising: - an exhaled air sensor (20), - an exhaled air measurement device (30), - computing means (40) capable of determining exhaled air data from the subject based on measurements taken by the device (30), - a memory (60) capable of storing measurements taken by the device (30) and / or data calculated by the means (40) and personal data of the subject, - a computing means (70) capable of determining a level of immune activity of the subject based on at least one exhaled air data generated in real time by the means (40) and / or stored in the memory (60), - a communication and management interface (80) adapted to present said level of immune activity of the subject and / or sub-scores of immunological activity, inflammatory activity, digestive inflammation, and / or pulmonary inflammation. Figure to be published with the abbreviation: Figure 4

Disclosed herein is a compound of formula (I): (I) where: A represents a tandem-lock biomarker responsive group; B represents a self-immolative linker; and C represents a chemiluminescent group, or a pharmaceutically acceptable salt or solvate thereof.

To provide compounds useful for imaging granzyme B by using medical imaging including positron tomography.SOLUTION: A method for imaging granzyme B in a cell or a tissue includes: i) a step of bringing a sample of the cell or tissue in contact with a compound of formula I or a pharmaceutically acceptable salt thereof; and ii) a step of imaging the cell or tissue by an appropriate imaging method and thus imaging granzyme B in the cell or tissue. In the formula, A includes one or a plurality of imaging agents, B denotes an arbitrary selected linking group, and C denotes a group binding to granzyme B.SELECTED DRAWING: None

A lymphatic system examination device includes a main body portion configured to position a lower body of a subject in an imaging region, an illumination unit configured to irradiate the lower body with excitation light; and an imaging unit configured to detect fluorescence emitted from the lower body. The illumination unit and the imaging unit are arranged on one side in a first horizontal direction. The illumination unit includes a first light emitting region and a second light emitting region arranged in a state of being separated from each other in a second horizontal direction. Each of the first light emitting region and the second light emitting region extends in a vertical direction in a state of facing the imaging region. The imaging unit faces the imaging region across a region between the first light emitting region and the second light emitting region.

A lymphatic system testing device is provided with: a main body unit having a mounting unit on which a subject stands and having an imaging region in which the lower body of the subject is positioned on the mounting unit; an illumination unit that irradiates excitation light to the lower body; and an imaging unit that detects fluorescence emitted from the lower body. The illumination unit and the imaging unit are disposed on one side in the first horizontal direction with respect to the imaging region. The main body portion further has a restricting portion. The restricting part is disposed along the upper end of the imaging region and restricts the movement of the subject to one side in the first horizontal direction.

The present technology provides for a remote continuous monitoring system that monitors a patient's vital signs and generates an alarm in response to detecting a likely onset of an adverse event. The monitoring system advantageously allows patients recovering from clinical treatments to do so at home, outside of a hospital. Furthermore, the monitoring system provides continuous monitoring of patient vital signs, which advantageously provides more information than intermittent manual measurements of patient vital signs typical in a hospital. The monitoring system, therefore, may more readily and more timely detect a likely onset of an adverse event.

Systems and methods are disclosed that facilitate providing guidance to a user during performance of a program or routine using a personalized avatar. In an aspect, a system includes a reception component configured to receive biochemical information about a physiological state or condition of a user, including information identifying a presence or a status of one or more biomarkers. The system further includes an analysis component configured to determine or infer one or more characteristics of the physiological state or condition of the user based on the information identifying the presence or the status of the one or more biomarkers, and a visualization component configured to adapt an appearance of an avatar presented to the user based on the one or more characteristics to reflect the one or more characteristics.

A lymphatic system examination device includes a main body portion including a placement portion on which a subject in which a fluorescent dye is injected into a lymphatic system stands, and configured to position a lower body of the subject in an imaging region on the placement portion; an illumination unit configured to irradiate the lower body with excitation light; and an imaging unit configured to detect fluorescence emitted from the lower body in response to irradiation of the excitation light. The placement portion is provided with a positioning portion that indicates a standing position of the subject.

Methods for detecting an immune response to Mycobacterium tuberculosis are provided. Aspects of the methods include contacting a biological sample comprising T cells from a subject with at least one M. tuberculosis peptide and determining the presence of T cells in the biological sample that specifically recognize the amino acid sequence of the at least one peptide, wherein the presence of T cells that specifically recognize the amino acid sequence of the at least one peptide indicates the subject has an immune response to M. tuberculosis. In certain aspects, the methods of the present disclosure may include treating a subject identified as having an immune response to M. tuberculosis. Also provided are a skin test and immunoassay kits for practicing the disclosed methods.

This lymphatic system inspection device is provided with: a main body part in which the lower body of a subject is positioned in an imaging region; an illumination unit that irradiates excitation light to the lower body; an imaging unit that detects fluorescence emitted from the lower body; a display unit that displays a fluorescent image of the lower body; and a control unit that controls the illumination unit, the imaging unit, and the display unit. The control unit controls at least one of the illumination unit and the imaging unit so as to change at least one of the light emission time of the illumination unit and the exposure time of the imaging unit, thereby generating a plurality of types of fluorescent images as fluorescent images, and controlling the display unit so as to display the plurality of types of fluorescent images in parallel.

To provide an information processing device, an information processing method, and an information processing program capable of appropriately confirming a user's health condition.SOLUTION: In an information processing system 1 in which an information processing device 10 is connected to external devices, such as a smart phone 7 owned by another person, an infected person contact notification server 8, and a disaster prevention information notification server 9, via a wired or wireless network 5 in a communicable state, the information processing device 10 includes at least one processor. The processor receives information transmitted and addressed to a user, and when the received information includes risk information related to the user's surroundings, which is information affecting the user's health or safety, gives a command regarding measurement of biological information to a measuring device that measures the user's biological information.SELECTED DRAWING: Figure 1

To provide a lymphatic system examination device suitable for lymphatic system examination in a lower half of a subject's body.SOLUTION: A lymphatic system examination device is equipped with a placing part 21 on which a subject S injected with fluorescent dye in the lymphatic system stands, and includes a body part 2 for having a lower half L of the body of the subject S positioned in an imaging region R on the placing part 21, an illumination part 3 for irradiating the lower half L of the body with excitation light, and an imaging part 4 for detecting fluorescence emitted from the lower half L of the body according to the irradiation of the excitation light. The illumination part 3 and the imaging part 4 are arranged on one side in an X-direction with respect to the imaging region R. The body part 2 further includes a regulation part 26. The regulation part 26 is arranged along an upper end part Ra of the imaging region R, and regulates movement of the subject S to the one side in the X-direction.SELECTED DRAWING: Figure 3

A lymphatic system examination device includes a main body portion including a placement portion on which a subject stands, and configured to position a lower body of a subject in an imaging region, an illumination unit configured to irradiate the lower body with excitation light; and an imaging unit configured to detect fluorescence emitted from the lower body. The illumination unit and the imaging unit are arranged on one side in a first horizontal direction with respect to the imaging region. The main body portion further includes a restricting portion. The restricting portion is disposed along the upper end portion of the imaging region and restricts movement of the subject to one side in the first horizontal direction.

The present technology provides for a remote continuous monitoring system that monitors a patient's vital signs and generates an alarm in response to detecting a likely onset of an adverse event. The monitoring system advantageously allows patients recovering from clinical treatments to do so at home, outside of a hospital. Furthermore, the monitoring system provides continuous monitoring of patient vital signs, which advantageously provides more information than intermittent manual measurements of patient vital signs typical in a hospital. The monitoring system, therefore, may more readily and more timely detect a likely onset of an adverse event.

Systems and methods are disclosed that facilitate providing guidance to a user during performance of a program or routine using a personalized avatar. In an aspect, a system includes a reception component configured to receive biochemical information about a physiological state or condition of a user, including information identifying a presence or a status of one or more biomarkers. The system further includes an analysis component configured to determine or infer one or more characteristics of the physiological state or condition of the user based on the information identifying the presence or the status of the one or more biomarkers, and a visualization component configured to adapt an appearance of an avatar presented to the user based on the one or more characteristics to reflect the one or more characteristics.

This lymphatic system inspection device is provided with: a main body part which has a placement part on which a subject having a fluorescent dye injected into the lymphatic system stands, and in which the lower body of the subject is positioned in an imaging region on the placement part; an illumination unit that irradiates excitation light to the lower body; and an imaging unit that detects fluorescence emitted from the lower body in response to the irradiation of the excitation light. A positioning part indicating the standing position of the subject is arranged on the carrying part.

Embodiments herein describe systems and methods for generating a surgical risk score. Various embodiments obtain multi-omics data, such as genomics, transcriptomics, and proteomics, from an individual. In certain embodiments, a machine algorithm is used to generate a surgical risk score based on the multi-omics data. In further embodiments, clinical data is further used in determining the surgical risk score. The present invention relates to predicting surgical outcomes, and more specifically, to predicting surgical outcomes, such as post-operative infections and surgical site complications, from clinical and multi-omics data using machine learning models.

A computerized system for measuring and / or detecting human responses or conditions based on data from wearable sensors worn in a natural free living environment. Based on the measurement and / or detection, various actions may be taken. Physiological data is acquired and instructions are transmitted to the vaccine manufacturer to alter the composition and / or dose of the vaccine.

The multi-modal biofeedback allergy defense massage control method comprises the following steps: acquiring multi-modal data of a user in a massage process in real time, determining whether the user has an allergy symptom before massage, and when the user has the allergy symptom before massage, outputting the acquired multi-modal data at a first moment as first multi-modal data; when the user does not have allergy symptoms before massage, constructing an antagonistic allergy risk model based on sympathetic / parasympathetic nerve activity indexes; performing real-time risk assessment by the antagonistic allergy risk model based on the multi-modal data acquired in real time, and outputting the multi-modal data as second multi-modal data when the risk assessment result is that the user has an allergy symptom; constructing a massage control model, and adjusting massage parameters of the massage equipment based on the first multi-modal data or the second multi-modal data by adopting the massage control model; according to the invention, the massage parameters of the user who is allergic or allergic in the massage process can be adjusted, so that the allergy symptom is relieved.

A computerized system for measuring and / or detecting responses or conditions in human beings based on data from wearable sensors worn in a natural free-living context. Based upon the measurements and / or detection, various actions can be taken. Physiological data is taken and instructions are transmitted to a vaccine manufacturer to alter a composition and / or dosage of a vaccine.

A lymphatic system examination device includes a main body portion including a placement portion on which a subject in which a fluorescent dye is injected into a lymphatic system stands, and configured to position a lower body of the subject in an imaging region on the placement portion; an illumination unit configured to irradiate the lower body with excitation light; and an imaging unit configured to detect fluorescence emitted from the lower body in response to irradiation of the excitation light. The placement portion is provided with a positioning portion that indicates a standing position of the subject.

The method involves using a digital badge device worn on the chest of a user to visually convey personal attributes to others in line of sight. It begins by configuring the badge device to communicate wirelessly with the user's mobile device. Next, a personal attribute of the user is determined based on input from the user or device-captured data. This attribute could relate to the user's affiliation, emotional state, physical activity, and more. Finally, a pre-defined color and / or symbol code representing the determined attribute is displayed on the badge device's screen for others to see. This provides an easily interpretable visual cue to communicate specific personal attributes to different users. By employing this method, the badge wearer can convey information about themselves without the need for verbal communication. The method offers a convenient and efficient way to signal personal attributes in situations where direct interaction may be limited or impractical.

The present invention relates to a computerized system for measuring and / or detecting a response or condition in a human being based on data obtained from a wearable sensor worn in a natural free-living situation. Based on the measurement and / or detection, various actions may be taken. Physiological data may be obtained and instructions to modify the vaccine composition and / or dosage may be sent to the vaccine manufacturer.