61 results about "Anxiety state" patented technology

The invention discloses an anxiety state detection and feedback system based on EEG signals. The detection and feedback system comprises specially-made portable EEG signal monitoring equipment, an EEGsignal analysis system and an anxiety state analysis algorithm. Working principles of the detection and feedback system are as follows: (1) the specially-made portable EEG signal monitoring equipmentcollects brain wave data of a user and transmits the brain wave data to the EEG signal analysis system in real time; (2) after receiving the data, the EEG signal analysis system decodes and preprocesses the data, and then performs signal identification through a brain wave data machine learning model by applying the anxiety state analysis algorithm; and (3) when the system identifies the signal data characteristics of the user entering an anxiety state, the anxiety state is fed back to the equipment and a terminal in real time for feedback.

The embodiment of the invention provides an anxiety state detecting method and device, and relates to the technical field of medical electronics. The method comprises the steps of obtaining three-dimensional acceleration data of a user; then judging whether the three-dimensional acceleration data of the user satisfies a condition of false anxiety features or not after it is detected that the usershows anxiety physiological features, and if not, determining that the user is in the anxiety state. In this way, the three-dimensional acceleration data is utilized to exclude the false anxiety features, thus a true anxiety state of the user is accurately obtained, and the user is reminded to take measures as early as possible to improve the health.

An embodiment of the invention discloses an early warning method, device and equipment for an anxiety state and a storage medium. The method comprises the following steps: acquiring resting state data of a monitored user in real time by wearing equipment; if the monitored user is determined to be in the anxiety state according to the resting state data of the monitored user, carrying out anxiety early warning on the monitored user. By the method, the anxiety state of the monitored user can be judged objectively, early warning reminding on the monitored user is carried out when determining that the monitored user is in the anxiety state, then the monitored user can take some measures to soothe the anxiety, and the circumstance that the monitored user remains in the anxiety state for a long time to affect health is avoided.

The invention discloses an anxiety state intervention method and system based on EEG signals, and the method comprises the following steps: EEG signal collection equipment collects electroencephalogram signals of a wearer, amplifies and encodes the collected electroencephalogram signals, and transmits the electroencephalogram signals to a data analysis system; the data analysis system analyzes, recognizes and classifies the received electroencephalogram signals to obtain the anxiety degree, and transmits the anxiety degree to the perception nerve regulation and control system to trigger the perception nerve regulation and control system to send tactile stimulation to the target brain area of the user. According to the anxiety degree of the user, the perceiving nerve regulation and control system can be automatically triggered to apply stimulation of different time lengths, and the beneficial effect of relieving anxiety in a targeted and intelligent mode is achieved.

The invention relates to the field of animal models, in particular to a construction method of a psoriasis animal model. The construction method comprises the application of imiquimod to induce psoriasis-like lesions in an anxious animal. The constructed mice can not only reflect the anxiety state of clinical patients, but also aggravate the psoriasis-like lesions, and prolong the maintenance timeof psoriasis-like lesions induced by imiquimod.

The invention discloses a traditional Chinese medicine preparation for treating the FD (Functional Dyspepsia) with a depression and anxiety state. In the traditional Chinese medicine, the FD generally belongs to the scopes of stomachache, distention and fullness of the traditional Chinese medicine according to the characteristics of symptoms of the FD, and the most common symptoms of the FD include spleen deficiency, qi stagnation, liver-stomach disharmony, liver stagnation and spleen deficiency. The traditional Chinese medicines, namely jasminum grandiflorum, begonia yunnanensis, cyperus michelianus, habenaria buchneroides, polyalthia nemoralis, cicerbita cyanea, castanopsis hystrix, flos mume, plagiopus oederi and rhodobryum roseum are selected and decocted into a decoction with water. Clinical tests show that the total effective rate of the traditional Chinese medicine preparation reaches 90% and is obviously superior to that of a control group.

The invention provides a speech-based anxiety prediction model generation method and an anxiety prediction system, and the method comprises the steps: 1, collecting speech of a text read by the user and the SAS scale score of the user, and marking the speech with the score; and 2, extracting voice features of the voice, and constructing an anxiety prediction model by using a neural network. According to the invention, automatic recognition of the tested anxiety state is realized through machine learning by using the voice of the reading text, the system is convenient to operate and deploy, andthe anxiety recognition and prediction convenience is improved.

The invention aims to provide a traditional Chinese medicine for improving postoperative anxiety state in patients with thyroid cancer. The traditional Chinese medicine is prepared from radix bupleuri, radix scutellariae, pericarpium citri reticulatae, pinellia ternata, bamboo shavings, fructus aurantii immaturus, radix gentianae, fructus gardeniae, cassia seed, chrysanthemum, white paeony root, radix rehmanniae, tuber fleeceflower stem, magnet, mother of pearl, rhizoma nelumbinis, leech, centipede, spina gleditsiae, Chinese prickly ash, liquorice, spica prunellae, seaweed, poria cocos and white atractylodes rhizome. The traditional Chinese medicine is prepared by the steps: mixing the traditional Chinese medicines together, adding water, soaking for half an hour, boiling with high heat, then changing to gentle heat, decocting for 30 min, and filtering to obtain a first filtrate; adding water to the filter residue, boiling with high heat, then changing to gentle heat, decocting for 30min, and filtering to obtain a second filtrate; and mixing the two filtrates evenly, concentrating to 200-300 mL, and thus obtaining the product. The traditional Chinese medicine is prepared by the pure traditional Chinese medicines, has the efficacies of clearing liver and purging fire, activating blood circulation and removing blood stasis, preventing and delaying the recurrence and metastasis of thyroid cancer, is an innovation in medicines of postoperative rehabilitation treatment for thyroid cancer, and has remarkable economic and social benefits.

The embodiment of the invention discloses a determining method, device and equipment of an anxiety state and a storage medium. The determining method comprises the steps that resting state data of a user to be detected is acquired; according to the resting state data, function linkage intensity between a nucleus accumbens brain area and one or more first selected brain areas around the nucleus accumbens brain area of the user to be detected is calculated; if it is determined that the function linkage intensity meets a first anxiety condition, LFP signals of one or more target brain areas of the user to be detected are acquired; if it is determined that theta rhythms of the LFP signals of the target brain areas meet a second anxiety condition, it is determined that the user to be detected is in the anxiety state. According to the embodiment, the method for objectively evaluating the anxiety state of the user is provided and solves the problem of existence of subjective factors in evaluation of the anxiety state of the user to be detected in the prior art.

The invention relates to a formula and a preparation method of a nepenthe apple juice beverage capable of improving sleep quality. The nepenthe apple juice beverage is prepared from the following raw materials in parts by weight: 80-120 parts of gamma-aminobutyric acid, 400-600 parts of spina date seeds, 150-250 parts of poria cocos, 400-600 parts of nepenthes, 30-60 parts of mimosa pudica and 800-1200 parts of apple juice concentrate, traditional Chinese medicine components are used for nourishing heart and liver and tranquilizing and allaying excitement, the anxiety state of people is improved through the gamma-aminobutyric acid, the sleep quality of people is improved through the gamma-aminobutyric acid, the apple juice concentrate is added, so that not only is the taste of the product improved, but also a plurality of vitamins can be provided, and nerves can be relieved, so that the sleep quality is improved.

The invention belongs to the field of nutrient substance research, and particularly relates to a nutritional composition beneficial to improvement of neural behaviors and cognition. The nutritional composition provided by the invention comprises necessary active ingredients shown in the following (i) and (ii): (i) lactose-N-neotetraose, (ii) 1, 2-diacyl-sn-glycerol-3-phosphorylcholine, and (iii) 1, 2-diacyl-sn-glycerol-3-phosphorylcholine. The nutritional composition comprises lactose-N-neotetraose and 1, 2-diacyl-sn-glycerol-3-phosphorylcholine, and in the nutritional composition, the mass ratio of the lactose-N-neotetraose to the 1, 2-diacyl-sn-glycerol-3-phosphorylcholine is 1: (0.010-2.0). The lactose-N-neotetraose and the 1, 2-diacyl-sn-glycerol-3-phosphorylcholine can achieve a synergistic effect to improve filial generation repeated engraving behaviors caused by maternal immune activation, decrease of social behavior ability and decrease of anxiety state and memory and recognition ability.

The invention discloses a device for examining anxiety degrees on the basis of LZC (Lemp-Ziv complexity). The device comprises electroencephalography signal acquisition equipment, a preprocessing module, an analysis and computation module and a classification module. The electroencephalography signal acquisition equipment is used for acquiring EEG (electroencephalography) signals in 8-minute eye-open and eye-closed rest states; the preprocessing module is used for extracting four frequency bands delta, theta, alpha and beta of the EEG signals after processing such as down-sampling, filtering and artifact removing is carried out on the EEG signals; the analysis and computation module is used for nonlinearly analyzing LZC for the four frequency bands of the EEG signals, sequentially computing LZC values of the four frequency bands by the aid of split time sequences used as units, and computing anxiety coefficients according to the obtained LZC values of the four frequency bands, and theobtained anxiety-free, mild-anxiety and moderate and severe-anxiety coefficients can be used as judgment indexes for examining the anxiety degrees; the classification module is used for applying support vector machines to building anxiety degree classification models by the aid of input data which are anxiety coefficient characteristic matrixes of anxiety-free, mild-anxiety and moderate and severe-anxiety crowds, and the anxiety coefficient characteristic matrixes are obtained after LZC characteristics of various leads are extracted, so that an anxiety-free state, a mild-anxiety state and a moderate and severe-anxiety state can be accurately, objectively and automatically classified.

The invention discloses a return anxiety intervention method and system based on VR scene self-adaption and data feedback, and relates to the technical field of return anxiety intervention methods.The return anxiety intervention method comprises the steps that occupational attributes, disease stages and psychological state evaluation data of a user are collected, and physiological baseline information obtained by wearable equipment is combined; constructing an initial user portrait containing individual features and function states; matching a preset intervention path template according to the initial user portrait, and generating a personalized VR training scheme with a module sequence, a scene difficulty level and a training period; executing the personalized training scheme in a virtual reality environment, carrying out commuting simulation, task operation and social interaction training through an immersive office scene, and synchronously collecting multi-modal physiological response data of a user in a training process; the anxiety level of the user is dynamically evaluated based on physiological response data in the training process, and when it is detected that the anxiety state exceeds a preset tolerance range, the stimulation intensity of the current scene is automatically reduced, and a relaxation bootstrap program is started.

The invention discloses application of an Hspa5 inhibitor in preparation of a medicine for preventing or treating anxiety disorder. An anxiety mouse model is constructed through chronic constraint stress (CRS), and in combination with medial amygdala kernel (MeA) transcriptome sequencing and qPCR verification, it is found that the endoplasmic reticulum molecular chaperone Hspa5 is remarkably up-regulated in the anxiety state. Furthermore, an Hspa5 specific inhibitor HA15 is locally injected into a MeA brain region, so that the anxiety-like behavior induced by the CRS is remarkably improved, and the exploration time of an open field experiment central region, the exploration time of an open arm of an elevated cross labyrinth and the exploration time of a bright box of a bright-dark box experiment are prolonged. The invention discloses the function of Hspa5 as a novel anti-anxiety target for the first time, and provides a direct experimental basis and a transformation direction for developing a novel anti-anxiety drug which is non-monoamine and targets an endoplasmic reticulum homeostasis.

The embodiment of the invention discloses a multi-user emotion monitoring method and device, equipment and a storage medium. The method comprises the steps that anxiety states of two or more monitoring users in a user cluster are monitored and set; if it is determined that in a set time interval, the number of users which have anxiety states is beyond a set user number threshold value, a group emotion relieving strategy is adopted to adjust group emotions of the user cluster. According to the multi-user emotion monitoring method, when it is monitored that multiple users have the anxiety states in the user cluster, the group emotion relieving strategy is adopted to adjust the group emotions of the user cluster, and the situation is effectively avoided that the user cluster anxiety phenomenon is caused by continuous group activities.

The invention discloses an oral liquid for improving memory. The oral liquid comprises the following raw materials in parts by weight: 40-200 parts of cannabidiol, 75-250 parts of American ginseng extract, 40-150 parts of taurine, 50-250 parts of phosphatidylserine, 30-250 parts of blueberry extract, 3-10 parts of sucralose and 0.3-0.5 part of preservative. The invention relates to the technical field of health beverages. In the invention, cannabidiol has a function of stopping human nervous system from being influenced by some polyphenols, an antianxiety effect and a nerve-soothing effect; American ginseng extract has the effects of calming and boosting nerve growth to the central nervous system; under the synergistic effect of cannabidiol and American ginseng extract, the anxiety state of people can be relieved and the brain memory function can be effectively enhanced; combined with taurine, phosphatidylserine and blueberry extract, the mixture of cannabidiol and American ginseng extract is capable of promoting sleep quality, relieving pressure, helping people relax, preventing cranial nerve from ageing, boosting brain power and obviously improving memory; sucralose is added, sothat the sweetness of oral liquid is greatly increased and the taste is nice.

The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition with the effects of treating atrial fibrillation and improving anxiety, a medicine and a preparation method and application thereof. When the traditional Chinese medicine composition provided by the invention is combined with auricular point pressing beans to treat patients with atrial fibrillation and anxiety, clinical symptoms of atrial fibrillation and anxiety can be further improved, specifically, the score of traditional Chinese medicine syndromes is reduced, the effective rate of electrocardiograms and the clinical effective rate of anxiety are improved, the life quality of the patients is improved, and no obvious adverse reaction exists. Meanwhile, a traditional Chinese medicine oral administration and traditional Chinese medicine external treatment combined method is adopted, syndrome differentiation treatment can be carried out from the holism concept, the holographic therapy of external treatment of internal diseases can be utilized to the maximum extent, and a simple, convenient, safe and effective treatment thought is provided for early prevention, early diagnosis and early treatment of more diseases.

A system is provided.SOLUTION: The system includes a camera monitor means for monitoring the behavior and expression of a care-receiver and detecting an anxiety state, an excretion prediction means for collecting bio data of the care-receiver and predicting the necessity of excretion, a control means for determining a response to the care-receiver based on the anxiety state and the necessity of excretion, and a display means for displaying an avatar familiar to the care-receiver to divert the attention of the care-receiver from excretion.SELECTED DRAWING: Figure 1

The invention relates to a pharmaceutical composition containing a calcium channel blocker (CCB for short) and paroxetine. The pharmaceutical composition is composed of a medicinal dose of CCB, a medicinal dose of paroxetine and a pharmaceutically acceptable carrier. The invention provides an application of the pharmaceutical composition in preparation of a medicine for treating hypertension complicated with anxiety state (symptom) or depression state (symptom). Through the implementation of the invention, the suitable therapeutic medicine is provided for patients with the physical and mentaldiseases, the medication compliance of the patients can be improved, the curative effect is improved, the life quality is improved, and the medical cost is reduced.

The invention discloses an extract for promoting health and application thereof, and belongs to the technical field of medical and edible dual-purpose and traditional Chinese medicine health care, and the extract is a special extract obtained from beautiful millettia roots. The beautiful millettia root extract exerts new activity for promoting female health through a new mechanism, and the clinical effect is obviously improved. Experimental research proves that the extract promotes self-renewal of female germline stem cells and directional differentiation of the female germline stem cells into oocytes by promoting expression of Notch1, HES1 and HES5 in a Notch signal channel and regulates the female progestational hormone level, and shows the effects of promoting and recovering development of a second sexual character and preventing symptoms of polycystic ovarian syndrome on ovarian development disorder, and has a good application prospect. The radix millettiae speciosae extract is capable of promoting female physical development and maturation, delaying premature ovarian failure, relieving female depression and anxiety states and keeping female health, belongs to a new target and new mechanism, and makes up the mechanism blank of the radix millettiae speciosae extract in the aspect of keeping female health. The application has innovativeness.

The invention belongs to the technical field of medicinal and edible beverages, and particularly relates to a day lily composite plant beverage with the effects of soothing the nerves and relieving depression and a preparation method of the day lily composite plant beverage. The beverage comprises plant extracts of day lily, honeysuckle, sophora flower, liquorice, rose, albizia flower, schisandra chinensis and the like, and sugar, an acidity regulator, a stabilizer and water are used as auxiliary materials. By optimizing the compatibility proportion and a grouping extraction process, effective components of various plants are reserved, a synergistic effect is formed, and depression and anxiety states are relieved in a targeted manner. The preparation method comprises the steps of plant pretreatment, grouped extraction, vacuum concentration, component blending, high-temperature instantaneous sterilization and the like. Animal experiment results show that the beverage disclosed by the invention can effectively improve depression-like behaviors of mice, has good potential of soothing nerves and regulating emotions, and is suitable for development of daily functional beverages.

An anxiety map display device according to the present disclosure includes a memory, and a processor coupled to the memory. The processor is configured to: acquire an anxiety state of a driver during driving; acquire position information of a vehicle during driving; acquire a driving situation of the vehicle during driving; generate an anxiety map indicating an anxiety occurrence position corresponding to a predetermined driving situation for the driver based on the position information and the driving situation when acquiring a predetermined anxiety state for the driver; and display the generated anxiety map for the driver as an individual anxiety map.

The invention provides an application of fructose diphosphate in preparation of a medicine for treating affective disorders. Experimental results of the invention show that the fructose diphosphate can improve depression and anxiety states, and can effectively treat the affective disorders, especially has a significant therapeutic effect on epileptic comorbidity affective disorders caused by epilepsy. Therefore, the fructose diphosphate has very good application prospects in the preparation of the medicine for treating the affective disorders, especially the epileptic comorbidity affective disorders.

The invention provides an anxiety state recognition method based on a multi-modal signal. A convolutional neural network (CNN), a gated recursive unit (GRU) and a deep learning model of a frequency band attention mechanism are combined. According to the method, spatial and temporal features are extracted from EEG and HR signals and weighted, key features related to anxiety emotion can be effectively captured, and accurate anxiety state classification is carried out. The method comprises the following steps: firstly, extracting each frequency band characteristic of an EEG signal through wavelet transform or short-time Fourier transform, and calculating information quantity indexes such as Shannon entropy and the like; the heart rate signal provides physiological information of emotional fluctuation by calculating heart rate variability (HRV) characteristics. Then, the CNN is used for extracting spatial features of the EEG signals, a frequency band attention mechanism dynamically weights features of all frequency bands, the GRU captures time sequence dependence of the EEG and the heart rate signals, and finally the anxiety state is output through a classification layer. According to the method, accurate real-time monitoring and intervention of the anxiety state can be realized, and powerful technical support is provided for emotion health management.

Saturated and unsaturated 3-pyridyl-benzocycloalkylmethyl-amines=compounds corresponding to formula (I),wherein the various substituents have the meaning provided in the description, and pharmaceutical formulations containing these compounds and methods for producing these compounds and related pharmaceutical formulation, and to methods for treating or inhibiting pain, depression and / or anxiety states.

The embodiment of the invention discloses a multi-user emotion monitoring method, device, equipment and storage medium. The method includes: monitoring and setting the anxiety state of at least two monitoring users in the user cluster; if it is determined that within the set time interval, the number of users in the user cluster in the anxiety state exceeds the set number threshold, then adopting a group Emotional soothing strategies adjust the group mood of the user cluster. When the above method monitors the anxiety of many people in the user cluster, it adopts an emotional soothing strategy to adjust the group emotions, effectively avoiding the occurrence of user cluster anxiety caused by the continuation of group activities.

The invention belongs to the technical field of medical research, and particularly discloses an anxiety index and life quality influence assessment method based on an HRV index, and the method comprises the steps: collecting the HRV data of an individual; the collected HRV data are preprocessed; the preprocessed HRV data are input into a Transform neural network model, and training and testing are carried out; and evaluating the anxiety index and the life quality influence index of the individual by using the trained Transform neural network model, and outputting an evaluation result including the anxiety index and the life quality influence index, thereby realizing more comprehensive and accurate evaluation of the anxiety state and the life quality of the individual. The problem that an existing method for evaluating the psychological state, the physiological health and the life quality of an individual excessively depends on simple analysis of single or multiple indexes and lacks comprehensiveness and accuracy is solved.

The present application belongs to the field of food, and particularly relates to a nutritional composition and its use for improving sleep. The present application provides a nutritional composition comprising essential active ingredients as shown in (I) and (II) below: (I) casein phosphopeptide, (II) neutral non-fucosylated human milk oligosaccharide; wherein the neutral non-fucosylated human milk oligosaccharide at least comprises lacto-N-neotetraose, and in the nutritional composition, the mass ratio of the casein phosphopeptide to the lacto-N-neotetraose is 1:(0.1-15.0). The present application proposes that the combination of casein phosphopeptide and lacto-N-neotetraose can effectively improve sleep problems, and even can improve the anxiety state caused by these sleep problems, and the two have a synergistic effect.