The invention discloses a method for carrying out real 
silk fabric anti-crease and antibacterial finishing by virtue of a 
laccase-TEMPO process. Quinones active groups are generated through catalyzing 
tyrosine residual groups in real silks by 
laccase so that 
chitosan molecules are grafted on the real silks; then 2,2,6,6-tetramethylpiperidine-
nitrogen oxide (TEMPO) is added and is used for catalyzing 
chitosan and 
tyrosine in the real silks to generate formyl groups, so that the 
grafting amount and bonding firmness of the 
chitosan on the real silks are increased, and the real 
silk fabric anti-crease and antibacterial finishing is realized. The method comprises the following specific steps of: (1) catalytically oxidizing the 
tyrosine residual groups in the real silks by the 
laccase; (2) taking the chitosan and the quinones active groups in the real silks to react; (3) catalyzing the real silks by laccase-TEMPO to graft the chitosan; and (4) washing the real silks with water and then treating. Compared with traditional chemical cross-linking-process vacuum fabric anti-crease and antibacterial finishing, the method has the advantages that the 
grafting efficiency of the chitosan is high, 
enzyme treatment conditions are moderate, the real 
silk fabric anti-crease and 
antibacterial effect is relatively good and the strength of the fabric is improved.