78 results about "Lung volume reduction" patented technology

Methods, systems, devices and kits for performing lung volume reduction in patients suffering from chronic obstructive pulmonary disease or other conditions using and comprising minimally invasive instruments introduced through the mouth (endotracheally) to isolate a target lung tissue segment from other regions of the lung and reduce lung volume. Isolation is achieved by deploying an obstructive device in a lung passageway leading to the target lung tissue segment. Once the obstructive device is anchored in place, the segment can be aspirated through the device. This may be achieved by a number of methods, including coupling an aspiration catheter to an inlet port on the obstruction device and aspirating through the port. Or, providing the port with a valve which allows outflow of gas from the isolated lung tissue segment during expiration of the respiratory cycle but prevents inflow of air during inspiration. In addition, a number of other methods may be used. The obstructive device may remain as an implant, to maintain isolation and optionally allow subsequent aspiration, or the device maybe removed at any time.

Methods and assemblies for reducing the volume of a lung. A plurality of anchors are anchored at different positions in the lung. A cord is attached to each of the anchors. The anchors are drawn towards one another via the cords to cause the lung to collapse, thus compressing the tissue in the lung and establishing a reduction in lung volume.

A surgical instrument for delivering energy to lung tissue, for example to cause lung volume reduction. In one embodiment, an elongated catheter has a handle portion that includes an interior chamber that is supplied with a biocompatible liquid media under pressure. An energy source delivers energy to the media to cause a liquid-to-vapor phase change within the interior chamber and ejects a flow of vapor media from the working end of the catheter. The delivery of energy and the flow of vapor are controlled by a computer controller to cause a selected pressure and selected volume of vapor to propagate to the extremities of the airways. Contemporaneously, the vapor undergoes a vapor-to-liquid phase transition which delivers a large amount of energy to airway tissue. The thermal energy delivered is equivalent to the heat of vaporization of the fluid media, which shrinks and collapses the treated airways. The treated tissue is the maintained in a collapsed state by means of aspiration for a short interval to enhance tissue remodeling. Thereafter, the patient's wound healing response causes fibrosis and further remodeling to cause permanent lung volume reduction.

A lung volume reduction system is disclosed comprising an implantable device adapted to be delivered to a lung airway of a patient in a delivery configuration and to change to a deployed configuration to bend the lung airway. The invention also discloses a method of bending a lung airway of a patient comprising inserting a device into the airway in a delivery configuration and bending the device into a deployed configuration, thereby bending the airway.

This invention relates to the treatment of a patient's lung, for example, a lung exhibiting chronic obstructive pulmonary disease (COPD) and in particular to methods and devices for affecting lung volume reduction, preferably for achieving acute or immediate lung volume reduction following treatment. The lung volume reduction is effected by delivering a condensable vapor at a temperature above body temperature to the desired regions of the patient's lung to damage tissue therein. Blood flow and air flow to the damaged tissue region is essentially terminated, rendering the target region non-functional. Alternative energy sources may be used to effect the thermal damage to the lung tissue.

The invention provides devices and systems for treating lungs. One aspect of the invention provides a lung device with an expandable member having an open lumen formed therethrough, the expandable (e.g., inflatable and compliant) member having an expanded diameter adapted to contact a circumferential wall portion of a lung air passageway. The device may also include a plug adapted to close the open lumen and a coupler adapted to couple the plug and the expandable member. Another aspect of the invention provides a lung device and delivery system including: an expandable member having an open lumen formed therethrough, the expandable member having an expanded diameter adapted to fit within a lung air passageway; and a delivery catheter adapted to deliver the expandable member to a lung air passageway, the delivery catheter having a coupler adapted to couple the catheter to the expandable member.

The present invention relates to methods and compositions for sealing localized regions of damaged lung tissue to reduce overall lung volume. The glue compositions provide a glue featuring an adhering moiety coupled to one or more other moieties including, for example, a cross-linkable moiety and/or one other adhering moiety. The methods and compositions of the invention find use, for example, in treating pulmonary conditions, such as emphysema.

An intra-bronchial device may be placed in an air passageway of a patient to collapse a lung portion associated with the air passageway. The device includes an obstructing member that prevents air from being inhaled into the lung portion to collapse the lung portion, and an anchoring device that anchors the obstructing member in the air passageway by engaging the obstructing member and the air passageway wall. The anchoring device may frictionally engage the obstructing member and the air passageway, or engage both by piercing. The engagement provided by the anchoring device may be releasable for removal of the obstructing member. The anchoring device may be balloon expandable from a first shape to a second shape that engages the obstructing member and the air passageway. The obstructing member may be a one-way valve.

The present invention relates to methods and compositions for sealing localized regions of damaged lung tissue to reduce overall lung volume. The glue compositions provide a glue featuring an adhering moiety coupled to one or more other moieties including, for example, a cross-linkable moiety and/or one other adhering moiety. The methods and compositions of the invention find use, for example, in treating pulmonary conditions, such as emphysema.

Devices, systems, and methods for diagnosing physiological parameters of the lungs and treating associated medical conditions are disclosed herein. In particular, certain embodiments permit detection of air flow in lung passageways, air leaks, gas concentration (in particular oxygen), and temperature measurements. Measurements obtained using the devices, systems, and methods disclosed herein may also be used to determine optimal treatment sites for medical conditions such as emphysema, COPD, or lung volume reduction.

Elongate implant structures can be introduced into an airway system to a target airway axial region, often to apply lateral bending and/or compression forces against the lung tissue from within the airways for an extended period of time. Structures or features of the implants may inhibit tissue reactions that might otherwise allow portions of the device to eventually traverse through the wall of the airway. The devices may enhance the area bearing laterally on the tissue of a surrounding airway lumen wall. Embodiments may have features which increase the device friction with the airway to allow the device to grip the surrounding airway as the device is deployed. An appropriate adhesive may be introduced around the device in the lung. Hydrophilic material may inhibit biofilm formation, or features which induce some tissue ingrowth (stimulation of tissue growth) may enhance implanted device supported

Apparatus (130) for use in wound therapy of mammals is described, the apparatus (130) comprising: a dressing covering the wound, the dressing being substantially sealed to prevent ingress of ambient atmospheric air to the wound; aspiration means (132) operably connected to a space between the dressing and the wound by an aspiration conduit (142) sealed to the point of entry between wound and dressing against ingress of ambient atmosphere, said conduit (142) being for aspiration of said wound and for removal of fluid from said space between said wound and said dressing; a waste container (148) for receiving aspirated fluid to be discarded operably connected to said aspiration conduit; and heating means (144) for heating said fluid in order to increase the vapor pressure thereof and to cause evaporation to reduce the volume of the fluid in the waste container (148). In a preferred embodiment of the present invention the waste fluid is also provided with a sparge gas.

Lung volume reduction is performed by the placement of a device (2) into a branch of the airway (34) to prevent air from entering that portion of lung. This will result in adsorption atelectasis of the distal portion of lung. The physiological response in this portion of lung is hypoxic vaso-constriction. The net effect is for a portion of lung to be functionally removed, i.e. a selected portion of lung is removed from both the circulation and ventilation. The build up of secretions is accommodated by using a valve (5, 15, 29) in the obstructive device, the valve opening upon coughing etc.

An anchored intra-bronchial apparatus for placement and deployment into selected airways and a method for using the same. When deployed, the apparatus creates a restriction of air flow to one or more targeted lung regions and achieves total lung volume reduction through a collapse or partial collapse of the targeted regions. The air flow valve of the apparatus includes a through lumen that permits drug delivery concurrent with lung volume reduction procedure