18 results about "Tissue trauma" patented technology

The invention belongs to the technical field of medical robots and minimally invasive surgery, and provides a robot control system and method for blue laser vaporization surgery of prostatic hyperplasia. Mapping the nuclear magnetic image volume data to a deformation field under an ultrasonic acquisition coordinate system, and deforming the preoperative nuclear magnetic image to an intra-operative ultrasonic space by using the deformation field to complete image registration; fusing the registered image with a stereoscopic vision system; the spatial depth of the surface of the target tissue is obtained from the endoscopic image so as to supplement navigation information; according to the utility model, the prostate deformation and probe posture change adaptive capacity in an operation is improved, the real-time visual closed-loop regulation and control capacity is improved, and the characteristics of small light spots, shallow heat diffusion, excellent hemostasis and the like of blue laser are combined, so that the vaporization and hemostasis precision in a tiny blood vessel dense area is ensured, and the problems of large tissue trauma and the like are avoided.

The present application relates to the field of medical tissue adhesive, in particular to a medical tissue adhesive, a medical tissue dry adhesive patch and a preparation method and application thereof. The present application provides a medical tissue adhesive, a medical tissue dry adhesive patch and a preparation method and application thereof. The medical tissue adhesive provided by the present application comprises: 1wt%-30wt% of acidic polyglutamic acid; 1wt%-30wt% of spherical protein; and the balance of water. The medical tissue adhesive provided by the present application has high tissue adhesion strength and fast hemostatic sealing speed in a wet physiological environment, meets the requirements of rapid and efficient tissue hemostatic sealing, and can be applied to rapid hemostasis of tissue wounds in a wet physiological environment, sealing of wound liquid leakage, healing and repair of wound tissue, and antibacterial of wounds. Experiments show that the dry adhesive patch made of the adhesive provided by the present application has high tissue adhesion strength in a wet physiological environment, and the adhesion strength to a wet pigskin tissue can reach more than 60kPa.

Particulated and reconstituted tissues comprising small, densely packed tissue microparticles encapsulated in a tissue specific promoting gel packed at a percolation threshold that can be transplanted into damaged tissue thereby facilitating regeneration following trauma to the tissue. The engineered microparticle construct for tissue replacement and repair, as taught herein, provides numerous benefits including (1) encouraging a regenerative response in damaged tissue regions, (2) mimicking the structural support of native tissue, (3) establishing an environment that promotes attachment, migration, and differentiation of infiltrating stem cells, and (4) providing a source of growth factors and other anti-catabolic growth factors and cytokines. Tissue specific microparticles packed together at, or past, their percolation threshold will provide the necessary mechanical environment and to best recapitulate and integrate with native tissue. The packing of microparticles, derived from the ECM of native tissue to a concentration past the percolation point will yield both the necessary biochemical and biomechanical properties necessary for reconstituting a specific tissue.

The invention discloses a device for accurately drilling an individualized steel needle into bone tissue and an operation method of the device, and relates to the technical field of orthopedic surgical instruments. The inner side of the guide plate is attached to the tibia, and a positioning part is arranged at the bottom of the guide plate; a guide sleeve; the auxiliary positioning frame is in a horseshoe shape and comprises a first positioning frame and a second positioning frame, a guide block is arranged at one end of the first positioning frame, the other end of the first positioning frame is connected with one end of the second positioning frame, a positioning hole is formed in the other end of the second positioning frame, the guide block is used for being inserted into the guide sleeve, and a first needle hole is formed in the guide block; the auxiliary rod is used for being inserted into the positioning hole, and a second needle hole is formed in the auxiliary rod; provided is a kirschner wire. The device can accurately drill a steel needle at a predetermined part of bone tissue at one time, so that the operation time is saved, tissue wounds are reduced, the risk of operative complications is reduced, and the operation efficiency is improved.

The application discloses a kind of bionic immune regulation double-network hydrogel and its preparation method and application, its preparation method is: GelMA-SPD and HAMA-NB are dissolved, join photo-crosslinking agent, crosslinking is carried out under light, obtain double-network hydrogel;GelMA-SPD is methacrylated gelatin-spermidine;HAMA-NB is methacrylated hyaluronic acid N-(2-aminoethyl)-4-[4-(hydroxymethyl)-2-methoxy-5-nitrophenoxy]-butyramide.The hydrogel prepared in the application has good biocompatibility, and the preparation process is simple, and can be degraded.The hydrogel of the application can be applied to tissue repair material or tissue engineering scaffold, and is expected to solve the immune rejection problem in the process of tissue organ transplantation, and is conducive to reducing inflammatory reaction and promoting the rapid healing of tissue trauma.

The present disclosure provides a system for injecting a drug eluting construct in a patient. The construct includes multiple cellular based microcaspules, wherein the multiple cellular based microcapsules create at least one of a plurality of layers or sections of microcapsules joined together to comprise an implant. There is a medicinal agent within the microcapsules. A syringe and needle inject the implant constructed of microcapsules into the patient at least one of during and after a surgical procedure. The medicinal agent controllably releases into the patient both immediately and at a delayed time.

The vertebral plate rongeur comprises a fixed rongeur body, a movable rongeur body and a handle assembly driving the movable rongeur body to slide on the fixed rongeur body. The movable clamp body comprises a clamp body sleeve with an internal channel, a drill rod penetrating through the clamp body sleeve, a bone grinding drill bit fixed to the far end of the drill rod, and a driving device connected with the near end of the drill rod; a part of the bone grinding drill bit is exposed outwards from the far-end opening of the forceps body sleeve; the driving device is used for driving the drill rod and the bone grinding drill to rotate; one end of the negative pressure drainage tube is communicated with an internal channel of the forceps body sleeve, the other end of the negative pressure drainage tube is connected with a suction device, and a through hole for sucking bone scraps into the forceps body sleeve is formed in the far end of the forceps body sleeve. In the operation process, the driving device drives the bone grinding drill bit to rotate through the drill rod, the bone grinding drill bit grinds bone tissue in the rotating process, bone scraps generated by grinding are sucked out of the body through the forceps body sleeve and the negative pressure drainage tube, a surgeon can operate continuously, operation time is shortened, and tissue wounds are reduced.

The present application provides a two-component in-situ adhesive based on supercharged protein and preparation method and use thereof. The two-component in-situ adhesive of the present application may be used for in-situ and rapid gelatinization at tissue wounds, showing excellent adhesion strength between tissues, and also showing excellent adhesion performance even on the moist tissue surface; after the gelatinization, its adhesive surface is soft, and may be used to achieve the effects of moist wound hemostasis, wound restoration and the like, for example, it may be used for assisting hemostasis in vascular reconstruction closure, or assisting suture in cranial suture site; at the same time, the adhesive of the present application also has the advantages of simple and rapid preparation process, no need for special devices, rapid adhesion and biocompatibility and the like.

The present invention relates to a surgical device, for the precise and efficient infiltration of fluids into tissues during laparoscopic surgical procedures. This device comprises a metallic, tube-like body (T) having an interanl hollow cavity that includes a holding area (H) and an infiltration nozzle (IN), which are key components facilitating its operation. The body (T) of the canula is designed to be long enough to reach deep into the abdominal cavity, with a holding area (H) equipped with a louver lock (LL) at its upper end. This lock (LL) allows for the secure attachment of syringes or fluid lines, ensuring stable and controlled fluid delivery. The infiltration nozzle (IN), located at the lower end of the body (T), features a distinct 90°degree bend terminating in a blunt beveled end (B). This design is specifically optimized to minimize tissue trauma while maximizing the precision and effectiveness of fluid dispersion directly at the surgical site.

The application provides a non-contact channel device suitable for hysteroscopy diagnosis and treatment, which comprises a sealed cylinder with open ends, a cover is arranged at the opening of one end of the sealed cylinder, the cover is detachably arranged, a filter assembly is arranged in the sealed cylinder, a drainage pipe is arranged on the side surface of the sealed cylinder and communicates with the inner cavity of the sealed cylinder, the drainage pipe is located between the cover and the filter assembly, and a first punch hole and a second punch hole are arranged on the side surface of the cover. The non-contact channel device suitable for hysteroscopy diagnosis and treatment has good sealing and isolation effects in the use process, can avoid liquid spattering and large outflow of the cervical orifice in the diagnosis and treatment process, can establish a channel from the vaginal orifice to the cervix, most patients do not need to use a vaginal dilator and a cervical clamp, tissue trauma is reduced, the device is convenient for collecting samples and avoiding loss, and the clinical diagnosis accuracy is improved.

The application discloses a kind of shank and foot ankle fixing device based on ankle surgery, it is related to medical auxiliary equipment technical field, including base assembly, shank support plate assembly, suspension fixing assembly, foot bottom baffle;Base assembly includes support base and traction base, the bottom end of traction base is equipped with the plug-in column of the plug-in connection with support base, shank support plate assembly is equipped on support base;Shank support plate assembly includes first support plate and second support plate, and rotation component is equipped between first support plate and second support plate and support base and traction base;Suspension fixing assembly includes installation crossbeam on traction base, and installation crossbeam is equipped with mobile unit and can fix shank and ankle osteotomy guide plate.The system can flexibly adjust the position of shank and ankle in operation, and can not be displaced in the operation process of manual or electric osteotomy tool operated by surgeon, to provide accurate navigation support for minimally invasive operation, improve the operability and accuracy of operation, reduce tissue trauma.

The invention discloses a human body part tissue trauma equivalent evaluation method, and belongs to the field of human body trauma ballistic science. The method comprises the following steps of: firstly, obtaining a human body part tissue thickness-fragment residual velocity curve and an equivalent structure thickness-fragment residual velocity curve under the same fragment and initial velocity conditions by virtue of finite element and test design means; and by using the curve, when the tissue composition, thickness and fragment initial velocity of the human body part are known, obtaining the corresponding equivalent structure thickness. Then, an equivalent structure thicken-V50 value curve is obtained through a test, and a V50 value corresponding to the equivalent structure thickness is obtained from the equivalent structure thicken-V50 value curve; and finally, comparing the initial speed of the fragments with the V50 value, and judging whether the fragments can penetrate through the part of the human body or not. According to the method, rapid and quantitative judgment on whether the human body penetrates or not under the given fragment-speed condition is achieved through the three-step process of hyperbola mapping and V50 value criterion, and the method is an evaluation method which can avoid the ethical problem, can guarantee high precision and repeatability and is relatively low in cost.

Existing clinically adopted epicardial pacing leads mostly rely on surgical suturing or insertion of electrodes to the heart tissue. However, these approaches can cause tissue trauma during application and / or retrieval of the implants, potentially causing detrimental complications such as bleeding, tissue damage, and / or device failure. The present invention reports a bioadhesive epicardial pacing lead for atraumatic epicardial monitoring and stimulation of the heart in vivo to overcome the limitations of existing bioelectronic implants. The bioadhesive pacing lead is composed of an insulation layer, a conductive bioadhesive interface, a built-in reservoir, an electrode lead wire, and a fluidic channel. The bioadhesive pacing lead shows robust mechanical and electrical properties, biocompatibility, continuous epicardial monitoring and pacing capability, and rapid on-demand atraumatic employment and removal.

The application discloses a special needling device for joint adhesion release, which comprises a holding handle connected with a needle body and a closed metal frame structure. The needle body is composed of a connecting section and a smooth conical needle tip, the included angle between the needle tip and the connecting section is 160-170 degrees, and the surface is provided with a polished plating layer. The device is integrally bent and formed by a medical stainless steel rod, the length of the needle body is greater than that of the holding handle, and the bottom of the vertical holding part is a circular arc transition. The device has small needle insertion resistance and low tissue trauma, can realize fast needle insertion and extraction, can accurately release soft tissue adhesion in the superficial fascia layer, is stable and convenient to operate, is high in safety, has quick effect, and is suitable for the treatment of joint adhesion caused by cervical spondylosis, lumbar spondylosis and chronic soft tissue injury.

The fluid ablation treatment equipment comprises a handle, a main machine and a liquid path system, the liquid path system is located between the main machine and the handle, the handle and the main machine are connected through a cable, the handle comprises a guide-in sheathing canal, a puncture needle is arranged in the guide-in sheathing canal in a telescopic mode, and a control device is arranged in the handle. The control device controls the puncture needle to slide in the leading-in sheath tube, a steam tube is arranged in the leading-in sheath, a liquid heating device is arranged in the handle, and the liquid heating device is used for heating liquid in the steam tube. The visual minimally invasive interventional operation has the advantages that the sexual function is kept intact, the operation time is very short, the action range is accurate, and the tissue trauma is small.

The disclosure relates to ophthalmic implants, specifically a flexible, self-expanding spacer device deployable in subconjunctival, sub-Tenon's, or suprachoroidal spaces to manage intraocular fluids. The device addresses limitations of fixed-resistance drainage and fibrosis-related failure in glaucoma surgery by maintaining a controlled three-dimensional reservoir (bleb space) for aqueous humor outflow while minimizing tissue trauma. In one aspect, a shape-memory body transitions from a compressed, delivery-compatible state to an expanded configuration defining a convex internal volume, optionally with collapse-resistant reinforcements and tissue-engaging elements for atraumatic stabilization. Preferred embodiments include anterior relief geometry to avoid corneal contact and posterior flow-directing features to promote posterior bleb formation and uniform pressure control. A delivery member with a reduced-profile, tapered piercing tip and optional bent shaft enables minimally invasive ab externo implantation and controlled, coaxial deployment. Advantages include streamlined single-step delivery, stable long-term bleb architecture, reduced hypotony and fibrotic encapsulation, and compatibility with trabeculectomy and shunt-based outflow.

The disclosure relates to ophthalmic implants, specifically a flexible, self-expanding spacer device deployable in subconjunctival, sub-Tenon's, or suprachoroidal spaces to manage intraocular fluids. The device addresses limitations of fixed-resistance drainage and fibrosis-related failure in glaucoma surgery by maintaining a controlled three-dimensional reservoir (bleb space) for aqueous humor outflow while minimizing tissue trauma. In one aspect, a shape-memory body transitions from a compressed, delivery-compatible state to an expanded configuration defining a convex internal volume, optionally with collapse-resistant reinforcements and tissue-engaging elements for atraumatic stabilization. Preferred embodiments include anterior relief geometry to avoid corneal contact and posterior flow-directing features to promote posterior bleb formation and uniform pressure control. A delivery member with a reduced-profile, tapered piercing tip and optional bent shaft enables minimally invasive ab externo implantation and controlled, coaxial deployment. Advantages include streamlined single-step delivery, stable long-term bleb architecture, reduced hypotony and fibrotic encapsulation, and compatibility with trabeculectomy and shunt-based outflow.

The present disclosure relates to an injection catheter (10) comprising a shaft (12) with a proximal end (14) and a distal end (16) The shaft (12) includes a proximal braided tube section (12a) providing support, flexibility, and kink resistance, a distal non-braided tube section (12b) for enhanced flexibility, and a soft tip section (12c) at the distal end (16) designed to minimize tissue trauma during insertion or positioning. A hub (20) at the proximal end (14) of the shaft (12) features a lumen for connection to an external fluid delivery device, while a strain relief (18) molded around the junction between the hub (20) and shaft (12) imparts mechanical support, flexibility, and kink resistance.