34 results about "Brain swelling" patented technology

The present invention is directed to therapeutic compounds, treatment methods, and kits affecting the NCCa-ATP channel of neural tissue, including neurons, glia and blood vessels within the nervous system, and methods of using same. The NCCa-ATP channel is newly expressed in neural tissue following injury such as ischemia, and is regulated by the sulfonylurea receptor SUR1, being inhibited by sulfonylurea compounds, e.g., glibenclamide and tolbutamide, and opened by diazoxide. Antagonists of the NCCa-ATP channel, including SUR1 antagonists, are useful in the prevention, diminution, and treatment of injured or diseased neural tissue, including astrocytes, neurons and capillary endothelial cells, that is due to ischemia, tissue trauma, brain swelling and increased tissue pressure, or other forms of brain or spinal cord disease or injury. Agonists of the NCCa-ATP channel may be are useful in the treatment neural tissue where damage or destruction of the tissue, such as a gliotic capsule, is desired.

A composition comprising a novel Ca2+-activated, [ATP]i-sensitive nonspecific cation (NCCa-ATP) channel is described. The channel is found in mammalian neural cells and exhibits a different sensitivity to block by various adenine nucleotides, and is activated by submicromolar [Ca]i. The NCCa-ATP channel is activated under conditions of ATP depletion, which causes severe cell depolarization, followed by cell swelling. The NCCa-ATP channel is regulated by a sulfonylurea receptor and is inhibited by sulfonylurea compounds glibenclamide and tolbutamide. Methods employing compositions comprising the NCCa-ATP channel to screen for compounds that block the channel and the use of such antagonists as therapeutics in preventing brain swelling and damage are described. In addition, methods employing compositions comprising the Kir2.3 channel to screen for compounds that open the channel and the use of such antagonists as therapeutics in preventing brain swelling and damage are described.

The present invention is directed to a combination of therapeutic compounds and treatment methods and kits using the combination. In particular, one of the combination affects the NCca-ATP channel of neural tissue, including neurons, glia and blood vessels within the nervous system. Exemplary SUR1 and / or TRPM4 antagonists that inhibit the NCca-ATP channel may be employed in the combination. The combination therapy also employs one or more of a non-selective cation channel blocker and / or an antagonist of VEFG, NOS, MMP, or thrombin. Exemplary indications for the combination therapy includes the prevention, diminution, and / or treatment of injured or diseased neural tissue, including astrocytes, neurons and capillary endothelial cells, that is due to ischemia, tissue trauma, brain swelling and increased tissue pressure, or other forms of brain or spinal cord disease or injury, for example. In other embodiments, there are methods and compositions directed to antagonists of TRPM4, including at least for therapeutic treatment of traumatic brain injury, cerebral ischemia, central nervous system (CNS) damage, peripheral nervous system (PNS) damage, cerebral hypoxia, or edema, for example.

A cold plasma helmet application device for delivery of cold plasma benefits to the head of a patient. An appropriate gas is introduced into a helmet receptacle within a containment dome of the helmet. The gas is energized by one or more dielectric barrier devices that receive energy from a pulsed source. The dielectric barrier devices can be configured to match the treatment area. Such a device and method can be used to treat large surface areas treatment sites associated with the head, head trauma, brain cancer, the control of brain swelling with closed head injury or infection, as well as treating male pattern baldness.

A cold plasma helmet application device for delivery of cold plasma benefits to the head of a patient. An appropriate gas is introduced into a helmet receptacle within a containment dome of the helmet. The gas is energized by one or more dielectric barrier devices that receive energy from a pulsed source. The dielectric barrier devices can be configured to match the treatment area. Such a device and method can be used to treat large surface areas treatment sites associated with the head, head trauma, brain cancer, the control of brain swelling with closed head injury or infection, as well as treating male pattern baldness.

The invention relates to a medicament for treating arthralgia and myalgia. The medicament is prepare from the components in parts by weight as follows: 1000 parts of nux vomica, 100 parts of radix clematidis, 100 parts of caulis sinomenii, 100 parts of garden balsam stem, 100 parts of lycopodium clavatum, 100 parts of berba aristolochiae mollissimae, 100 parts of monkshood, 100 parts of radix aconiti agrestis, 100 parts of the root of red-rooted salvia, 100 parts of angelica sinensis, 100 parts of rheum officinale, 100 parts of dragon's blood, 100 parts of semen momordicae, 100 parts of eucommia ulmoides, 100 parts of cinnamon, 100 parts of radix angelicae pubescentis, 100 parts of notopterygium root, 100 parts of asarum, 100 parts of radix achyranthis bidentatae, 100 parts of homalomena occulta, 100 parts of anisetree bark, 100 parts of radices sileris, 100 parts of caper, 100 parts of monkshood, 100 parts of ligusticum wallichii, 100 parts of Chinese polyphaga, 100 parts of scorpio, 100 parts of centipede, 100 parts of frankincense, 100 parts of myrrh, 100 parts of leech, 60 parts of camphor, 60 parts of borneol, 20 parts of musk and 300 parts of zaocys dhumnade. The medicament provided by the invention can be used for treating cervical spondylosis, brain swelling cervical pain, scapulohumeral periarthritis, scapula back pain, pelvospondylitis, thoracic vertebra pain, elbow joint pain, pain in waist and lower extremities, lumbar disc herniation, cervical and lumbar spinal stenosis, osteoproliferation, ischiadic nerve pain, knee-joint dropsy, synovitis, knee pain and rheumatic arthritis.

A cold plasma helmet application device for delivery of cold plasma benefits to the head of a patient. An appropriate gas is introduced into a helmet receptacle within a containment dome of the helmet. The gas is energized by one or more dielectric barrier devices that receive energy from a pulsed source. The dielectric barrier devices can be configured to match the treatment area. Such a device and method can be used to treat large surface areas treatment sites associated with the head, head trauma, brain cancer, the control of brain swelling with closed head injury or infection, as well as treating male pattern baldness.

The present invention is directed to therapeutic compounds, treatment methods, and kits affecting the NCCa-ATP channel of neural tissue, including neurons, glia and blood vessels within the nervous system, and methods of using same. The NCCa-ATP channel is newly expressed in neural tissue following injury such as ischemia, and is regulated by the sulfonylurea receptor SUR1, being inhibited by sulfonylurea compounds, e.g., glibenclamide and tolbutamide, and opened by diazoxide. Antagonists of the NCCa-ATP channel, including SUR1 antagonists, are useful in the prevention, diminution, and treatment of injured or diseased neural tissue, including astrocytes, neurons and capillary endothelial cells, that is due to ischemia, tissue trauma, brain swelling and increased tissue pressure, or other forms of brain or spinal cord disease or injury. Agonists of the NCCa-ATP channel may be are useful in the treatment neural tissue where damage or destruction of the tissue, such as a gliotic capsule, is desired.

We have developed a novel method of brain surface dialysis that reduces intracranial pressure and modifies movement of extracellular fluid in a rat model of brain injury. A chamber with a semipermeable membrane at the site of brain contact is perfused with a hyperosmolar solution (e.g. 15% dextran, inulin, hydroxyethyl starch). It is also capable of providing local brain cooling. In principle, osmotic forces draw water and small molecules from the injured brain into the dialysis chamber thereby reducing brain swelling. The dialysate does not move into the brain.

A method to reduce brain injury and brain swelling includes performing active compression decompression cardiopulmonary resuscitation on an individual in a supine position. The individual's head, shoulders, and heart are elevated relative to the individual's lower body. The head is elevated to a height of between about 20 cm and 30 cm above the horizontal plane and the heart is elevated to a height of between about 3 cm and 10 cm above the horizontal plane. Chest compressions are performed on the individual and actively decompressing the individual's chest while the individual's head, shoulders, and heart are elevated. Intrathoracic pressure of the individual is regulated using an intrathoracic pressure regulation device both while the individual is in the supine position and while the individual's head, shoulders, and heart are elevated relative to the lower body, thereby reducing brain edema during CPR.

The invention discloses a radiation-proof health-care drape which comprises a drape fabric, cactus extract, negundo chaste tree fruit and fructus evodiae, and the drape fabric is made by cooking, soaking and drying the traditional Chinese medicines including cactus extract, negundo chaste tree fruit and fructus evodiae. The radiation-proof health-care drape has the health-care functions of absorbing radiation, protecting liver and promoting bladder, relieving hypertention and strengthening heart, dispelling cold and relieving diarrhea, and the like, as well as obvious effects on aid therapy of dizziness and brain swelling, mouthpiece aphtha and other diseases.

Methods and compositions comprising isothiocyanates or derivatives or metabolites thereof, for attenuating or preventing central nervous system tissue damage, and / or improving cognitive function, are disclosed. Treatment of head trauma, spinal cord injury, stroke, aging, neurological diseases, and other insults to the central nervous system that compromise the blood-brain barrier, cause brain swelling, central nervous system cell death, or cognitive or motor dysfunction, by administering an isothiocyanate such as sulforaphane, allyl isothiocyanate, phenylethyl isothiocyanate, or a related compound, is also disclosed.

The invention relates to a traditional Chinese medicine nursing soup, and solves the problems that a conventional hair-breeding and hair-blackening traditional Chinese medicine preparation can not alleviate symptoms such as neurasthenia and brain swelling. The traditional Chinese medicine nursing soup is a medicament prepared by the following components by weight: 75-85 parts of saponin, 48-53 parts of pothos, 93-105 parts of wild alpinia chinensis, 47-52 parts of polygonum multiflorum, 97-103 parts of tea seeds, 950-1,050 parts of sasangua cake, 46-52 parts of ganoderma lucidum, 27-33 parts of angelica sinensis and 18-23 parts of safflower. The invention also relates to an application method of the traditional Chinese medicine nursing soup. The application method can better alleviate symptoms such as neurasthenia and brain swelling. The formula and the application method are unique and have good curative effects for symptoms such as alopecia, hair loss and neurasthenia.

The invention relates to the technical field of equipment for chemical production and discloses environment-friendly reaction equipment for chemical production. The equipment comprises a kettle body,wherein a feeding port is formed in the top of the kettle body, an exhaust pipe with one end penetrating through and extending into an inner cavity of the kettle body is fixedly mounted at the top ofthe kettle body and located on the one side surface of the feeding port, a discharging port is obliquely formed in the side surface of the lower part of the kettle body, a gas guide pipe is inserted into an outlet of the exhaust pipe, an inlet of the gas guide pipe is communicated with the outlet of the exhaust pipe, an outlet of the gas guide pipe penetrates through and extends into a fixed granule removal box, and the bottom of the side surface of the fixed granule removal box is communicated with the bottom of the side surface of a purification box through a pipeline. The environment-friendly reaction equipment for chemical production has a high environmental protection function, the condition that toxic gas is directly exhausted and harms body health of workers is prevented, peculiar smell produced during production of chemical gas is adsorbed, discomfort symptoms such as dizziness, dazzling and the like caused by long-time inhalation of the workers are avoided, and the working efficiency is indirectly improved.

A composition comprising a novel Ca2+-activated, [ATP]i-sensitive nonspecific cation (NCCa-ATP) channel is described. The channel is found in mammalian neural cells and exhibits a different sensitivity to block by various adenine nucleotides, and is activated by submicromolar [Ca]i. The NCCa-ATP channel is activated under conditions of ATP depletion, which causes severe cell depolarization, followed by cell swelling. The NCCa-ATP channel is regulated by a sulfonylurea receptor and is inhibited by sulfonylurea compounds glibenclamide and tolbutamide. Methods employing compositions comprising the NCCa-ATP channel to screen for compounds that block the channel and the use of such antagonists as therapeutics in preventing brain swelling and damage are described. In addition, methods employing compositions comprising the Kir2.3 channel to screen for compounds that open the channel and the use of such antagonists as therapeutics in preventing brain swelling and damage are described.

The present disclosure provides dynamic cranial fixation devices and related methods for attaching a resected bone portion(s), or a bone flap, to the skull in such a manner that allows for brain swelling to occur with minimal constraint following a craniotomy or craniectomy. The present disclosure provides dynamic cranial fixation devices and related methods that provide outward movement of the bone flap as the brain swells underneath the bone flap to prevent or reduce a rise in the intracranial pressure. Once the brain swelling resolves, the dynamic cranial fixation devices and related methods of the present disclosure allow the bone flap to return to its original position (before resection) without further surgery, implantation or the like. Once the bone flap return to its original position (or substantially similar position), the bone flap may fuse with the neighboring bone(s), potentially with the assistance of one or more fusion aid.

We have developed a novel method of brain surface dialysis that reduces intracranial pressure and modifies movement of extracellular fluid in a rat model of brain injury. A chamber with a semipermeable membrane at the site of brain contact is perfused with a hyperosmolar solution (e.g. 15% dextran, inulin, hydroxyethyl starch). It is also capable of providing local brain cooling. In principle, osmotic forces draw water and small molecules from the injured brain into the dialysis chamber thereby reducing brain swelling. The dialysate does not move into the brain.

The invention discloses a health preserving pillow for conditioning and controlling insomnia, dizziness and brain swelling and a manufacturing method thereof. The health preserving pillow comprises apillow inner liner and a pillow cover, wherein the following raw materials in parts by weight: 15 to 25g of radix notoginseng, 15 to 25g of radix angelicae sinensis, 15 to 25g of radix astragali seu hedysari, 15 to 25g of dried orange peel, 15 to 25g of radix angelicae, 8 to 12g of Qianyexiang, 10 to 20g of murraya paniculate leaves, 8 to 12g of rhizoma kaempferiae, 8 to 12g of star anise, 8 to 12g of mentha leaves, 8 to 12g of fruit of cumin, 8 to 12g of zanthoxyli pericarpium, 8 to 12g of agilawood, 8 to 12g of dioscoreae rhizoma, 8 to 12g of fructus crataegi, 4 to 6g of musk and 2500g of soybeans are charged into the pillow inner liner. Various kinds of Chinese herbal medicine are charged into the pillow; the pillow is used during the normal sleeping of people; flavor is released from the pillow; when head brain acupuncture points and the pillow generate extrusion, the flavor enters the respiratory tract of people and each acupuncture point of the brain; the effects of nerve soothing, calming, muscle relaxing and blood activation are achieved, so that the goals of conditioning and controlling adverse phenomena of insomnia, dizziness and brain swelling are achieved; after the long-time use, users can be in good mood and emotions; the phenomena of insomnia, dizziness and brain swelling can gradually disappear.

A method and system are provided for reducing the extent and duration of brain swelling in a trauma or stroke victim requiring decompressive craniectomy. In an exemplary method, a medical procedure for inhibiting swelling of the brain includes the steps of performing a decompressive craniectomy to expose intracranial tissue, placing a cooling structure on the exposed intracranial tissue, and cooling the exposed intracranial tissue with the cooling structure. An exemplary system for performing the method includes a source of coolant, a cooling structure, and an umbilical connecting the source of coolant and the cooling structure and conducting cooling fluid therebetween, wherein the cooling structure is dimensioned to cover substantially all exposed intracranial tissue.

A traditional Chinese medicine oral liquid for treating rhinitis and sinusitis and a preparation method thereof belong to the technical field of traditional Chinese medicine preparations and preparation methods. The technical problem to be solved is to provide a traditional Chinese medicine oral liquid for treating acute and chronic rhinitis and sinusitis by rapidly removing and relieving nasal congestion and the resulting symptoms of headache and brain swelling, and reducing purulent mucus, and a preparation method thereof. The composition of the oral liquid includes Fangfeng, Xinyi flower, Asarum, Houttuynia cordata, Ligusticum edulis, peppermint, cocklebur, Shichangpu, notopterygium distilled extract, angelica dahurica, dandelion, Patrinia, Poria cocos, Passepartout, bellflower boiled Extraction and alcohol precipitation extract; the preparation method includes the steps of preparing distillation extract, preparing boiling and alcohol precipitation extract, merging and adjusting concentration. The preparation method can extract the volatile active ingredients contained in the crude drug to a maximum extent, and enhance the curative effect. After taking it, it can quickly relieve and relieve nasal congestion and the resulting headache, brain swelling and other symptoms, reduce pus, improve and restore olfactory function, and the total effective rate is 98.9%.

The invention discloses a cranial nerve activating and restoring liquid and belongs to the technical field of medicines. The cranial nerve activating and restoring liquid comprises plant nervonic acid, metallothionein MT3, menthol, camelina sativa seed oil, oil-soluble VB12, aspirin, oryzanol powder and rice oil. The nervonic acid and the metallothionein MT3 are adopted as main components, and reasonable auxiliary components are adopted as supplements. The auxiliary components can fully promote absorption of the nervonic acid and the metallothionein MT3 by human bodies and ensure function exertion of the nervonic acid and the metallothionein MT3. The cranial nerve activating and restoring liquid can be taken orally and absorbed through the intestinal tract or transdermal absorption through cerebral cortex tissues can be achieved through mist spraying at the outside of brain. The cranial nerve activating and restoring liquid is capable of activating and restoring rigidified deteriorative and deactivated brain cells, promoting brain development of children, improving the level of intelligence, improving brain functions of middle-young people, and inhibiting senile dementia and the Parkinson's disease, and has special effects on dizziness, brain swelling and hypomnesis which are caused by electric, magnetic and light radiation.

The present invention is directed to a combination of therapeutic compounds and treatment methods and kits using the combination. In particular, one of the combination affects the NCCa-ATP channel of neural tissue, including neurons, glia and blood vessels within the nervous system. Exemplary SUR1 and / or TRPM4 antagonists that inhibit the NCCa-ATP channel may be employed in the combination. The combination therapy also employs one or more of a non-selective cation channel blocker and / or an antagonist of VEFG, NOS, MMP, or thrombin. Exemplary indications for the combination therapy includes the prevention, diminution, and / or treatment of injured or diseased neural tissue, including astrocytes, neurons and capillary endothelial cells, that is due to ischemia, tissue trauma, brain swelling and increased tissue pressure, or other forms of brain or spinal cord disease or injury, for example. In other embodiments, there are methods and compositions directed to antagonists of TRPM4, including at least for therapeutic treatment of traumatic brain injury, cerebral ischemia, central nervous system (CNS) damage, peripheral nervous system (PNS) damage, cerebral hypoxia, or edema, for example.

The invention provides a limited and gradual decompression control system for acute cerebral hemispheric swelling. A method for the limited and gradual decompression control system comprises 'limited decompression' and 'gradual decompression', the 'limited decompression' includes decompression within a controllable range in a limited manner, the 'gradual decompression' includes gradual decompression at different steps, the cerebral dura mater of a patient is incised off to remove hematoma and contusion and laceration of the brain of the patient via multiple small scattered incisions, so that primary limited decompression is completed, and then a subdural space of the patient is expanded by a special cerebral dura mater incision tension-reduced repair method to complete decompression once again. In a surgery process, the cerebral dura mater covers swollen brain tissues and are not completely opened all along, and sudden 'pressure loss' can be avoided. Incarceration of brain tissues and surface blood vessels can be avoided by means of releasing a dura mater ring. In addition, a common method for releasing skin under galea aponeurotica in the orthopedics is used in a brain swelling surgery, recompression of scalp to the brain tissues can be avoided, a decompression effect is guaranteed, and death caused by acute cerebral hemispheric swelling is avoided.

The invention discloses a drug for treating high blood pressure and relates to Chinese traditional patent medicine. The drug is prepared from, according to a formula, by weight, 1-2 parts of smelly jasmine leaves, 1-2 parts of persimmon leaves and 10-20 parts of black Chinese olive leaves. The dried smelly jasmine leaves, the dried persimmon leaves and the dried black Chinese olive leaves are blended and smashed to be prepared into an agent, or capsules, or packed into packages through tea-brewing paper. The drug for treating the high blood pressure has the advantages of good curative effect with a total effective rate of treating the high blood pressure reaching to 97.5% and an efficiency show rate reaching to 86.9%, rapidness in effect and immediate effect for symptoms of brain swelling and fatigue, safeness and no toxic side effects for normal use, and easiness in obtaining raw materials and preparing and applying.

The invention relates to a traditional Chinese medicine nursing soup, and solves the problems that a conventional hair-breeding and hair-blackening traditional Chinese medicine preparation can not alleviate symptoms such as neurasthenia and brain swelling. The traditional Chinese medicine nursing soup is a medicament prepared by the following components by weight: 75-85 parts of saponin, 48-53 parts of pothos, 93-105 parts of wild alpinia chinensis, 47-52 parts of polygonum multiflorum, 97-103 parts of tea seeds, 950-1,050 parts of sasangua cake, 46-52 parts of ganoderma lucidum, 27-33 parts of angelica sinensis and 18-23 parts of safflower. The invention also relates to an application method of the traditional Chinese medicine nursing soup. The application method can better alleviate symptoms such as neurasthenia and brain swelling. The formula and the application method are unique and have good curative effects for symptoms such as alopecia, hair loss and neurasthenia.

The disclosed subject matter related to methods and apparatus for determining brain swelling in a patient as well as predicting an increase in intracranial pressure in the patient. The apparatus can include a transducer such as an ultrasound transducer communicatively connected to a controller via wires or via wireless communications device(s). A monitor and / or alarm device can be provided to notify a practitioner when the controller has determined brain swelling is occurring and / or when an imminent increase in intracranial pressure is likely to occur.

The invention relates to the technical field of ink production equipment, and discloses an environment-friendly reaction kettle for ink production with good purification effect. The outlet of the exhaust pipe is connected, the inlet of the air duct is fixedly installed on the top of the main casing, and the inlet of the air duct is inserted into the outlet of the exhaust pipe, and the outlet of the air duct penetrates and extends to the interior of the fixed particle removal box , the outer surface of the air duct is fixedly installed on the outer side of the main casing through a fixing block, and the bottom of the side of the fixed particle removal box is connected to the bottom of the side of the purification device through a pipe. The environmentally friendly reaction kettle for ink production with good purification effect has strong environmental protection function, prevents the direct discharge of toxic gas and endangers the health of the staff, absorbs the peculiar smell produced by the production ink, and prevents the staff from inhaling for a long time and causing dizziness, brain swelling or Dizziness and other discomfort symptoms, indirectly improve work efficiency.

The invention relates to a medicament for treating arthralgia and myalgia. The medicament is prepare from the components in parts by weight as follows: 1000 parts of nux vomica, 100 parts of radix clematidis, 100 parts of caulis sinomenii, 100 parts of garden balsam stem, 100 parts of lycopodium clavatum, 100 parts of berba aristolochiae mollissimae, 100 parts of monkshood, 100 parts of radix aconiti agrestis, 100 parts of the root of red-rooted salvia, 100 parts of angelica sinensis, 100 parts of rheum officinale, 100 parts of dragon's blood, 100 parts of semen momordicae, 100 parts of eucommia ulmoides, 100 parts of cinnamon, 100 parts of radix angelicae pubescentis, 100 parts of notopterygium root, 100 parts of asarum, 100 parts of radix achyranthis bidentatae, 100 parts of homalomena occulta, 100 parts of anisetree bark, 100 parts of radices sileris, 100 parts of caper, 100 parts of monkshood, 100 parts of ligusticum wallichii, 100 parts of Chinese polyphaga, 100 parts of scorpio, 100 parts of centipede, 100 parts of frankincense, 100 parts of myrrh, 100 parts of leech, 60 parts of camphor, 60 parts of borneol, 20 parts of musk and 300 parts of zaocys dhumnade. The medicament provided by the invention can be used for treating cervical spondylosis, brain swelling cervical pain, scapulohumeral periarthritis, scapula back pain, pelvospondylitis, thoracic vertebra pain, elbow joint pain, pain in waist and lower extremities, lumbar disc herniation, cervical and lumbar spinal stenosis, osteoproliferation, ischiadic nerve pain, knee-joint dropsy, synovitis, knee pain and rheumatic arthritis.

The invention belongs to the technical field of medicine, and particularly relates to an electric field device for treating tumors. According to the technical scheme, the electric field device for treating the tumors is composed of an electric field therapeutic instrument, a connecting wire, a power supply and an electric field therapeutic instrument controller. The electric field therapeutic apparatus is connected with a power supply through a connecting wire, and the electric field therapeutic apparatus and the electric field therapeutic apparatus controller receive and transmit wireless signals. The invention mainly solves the problem of carrying equipment for a long time in the treatment of brain swelling, also improves the compliance of patients, greatly improves the tumor inhibition effect due to 24-hour uninterrupted work, does not need to shave the head in the use method, and has little skin allergy; according to the method, only one-time installation is needed, the patch does not need to be repeatedly replaced, and the treatment cost is greatly reduced.

The present disclosure provides dynamic cranial fixation devices and related methods for attaching a resected bone portion(s), or a bone flap, to the skull in such a manner that allows for brain swelling to occur with minimal constraint following a craniotomy or craniectomy. The present disclosure provides dynamic cranial fixation devices and related methods that provide outward movement of the bone flap as the brain swells underneath the bone flap to prevent or reduce a rise in the intracranial pressure. Once the brain swelling resolves, the dynamic cranial fixation devices and related methods of the present disclosure allow the bone flap to return to its original position (before resection) without further surgery, implantation or the like. Once the bone flap return to its original position (or substantially similar position), the bone flap may fuse with the neighboring bone(s), potentially with the assistance of one or more fusion aid.