27 results about "Cutaneous allergy" patented technology

The invention relates to a novel application of animal bifidobacterium subsp. Lactis BGI-N3, in particular to an application of the animal bifidobacterium subsp. Lactis BGI-N3 in preparation of a preparation for relieving skin allergy. The invention finds that the bifidobacterium animalis subsp. Lactis BGI-N3 has a very remarkable effect in the aspect of relieving skin allergy, and the effect is specifically shown as follows: in an atopic dermatitis animal model, the dermatitis score, scratching times and percutaneous water loss are remarkably reduced, and the atopic dermatitis skin tissue damage condition is relieved; the immune organ edema condition is improved, the levels of Th2 type cell factors and inflammatory factors IL-6, TNF-alpha and IFN-gamma related to dermatitis are reduced, and the immune balance of the body is recovered; expression of fibroin and endothelial protein in skin tissue is improved, and the skin barrier is repaired; the level of antibacterial peptide in skin tissues is recovered, and the antibacterial activity of the skin is enhanced. Meanwhile, compared with a traditional chemical medicine for treating atopic dermatitis, the animal bifidobacterium subsp. Lactis BGI-N3 has no side effects such as weight loss, immune organ atrophy, immune imbalance and the like.

The invention provides double physical cross-linked silk fibroin composite gel as well as a preparation method and application thereof. A silk fibroin solution is cross-linked twice in a first cross-linking agent and a second cross-linking agent, the first cross-linking agent and the second cross-linking agent are hydroxyl cellulose or carboxyl cellulose or corresponding derivatives, the first cross-linking agent induces beta-folding in silk fibroin, the second cross-linking agent induces beta-folding among silk fibroin molecules, and the second cross-linking agent induces beta-folding among silk fibroin molecules. The first cross-linking agent and the second cross-linking agent are the same or different. According to the preparation method, the problem of skin allergy caused by adding a chemical cross-linking agent is avoided by precisely regulating and controlling a dual cross-linking mechanism in molecules and between molecules, the stability and the supporting property of the silk fibroin are improved, and the degradation period of the silk fibroin is prolonged.

The invention provides a probiotic composition as well as a preparation method and application thereof. The composition is prepared from lactobacillus rhamnosus GG, lactobacillus acidophilus NCFM, an anti-IL-4R alpha monoclonal antibody, an inulin-beta-glucan compound and sodium alginate-chitosan microspheres. The composition regulates immune balance through a specific probiotic strain, blocks an IL-4 / IL-13 signal channel in combination with an anti-IL-4R alpha monoclonal antibody, and improves viable bacterium stability and bioavailability through a microsphere delivery technology. The probiotic composition shows a remarkable anti-allergic effect in an atopic dermatitis mouse model, and can reduce the serum IgE level, reduce the skin inflammatory response and reduce the STAT6 phosphorylation level. The probiotic composition disclosed by the invention has a wide application prospect in the aspect of treating atopic dermatitis and other immune-related diseases.

The embodiment of the invention provides a real-time processing method and system for rapid identification and filing of emergency patients. Wherein the intelligent medical fabric is worn on the skin surface of a burn patient, reflected light intensity distribution and microvascular pulsation waveforms are captured, and the light transmittance and the sampling frequency are automatically adjusted; the reflected light intensity distribution and the microvascular pulsation waveform are converted into combined parameters and matched, and a grading alarm signal is triggered when a skin tolerance dynamic interval is exceeded; packaging the graded alarm signal and the real-time physical sign data of the patient into a cross-hospital transmission data packet, and sending a data sharing request to a cooperative hospital; performing feature space alignment on the burnt skin allergy feature spectrum to generate a cross-mechanism allergy reaction prediction model; and automatically reconstructing an allergy monitoring file of the burnt patient during detection and transfer. According to the technical scheme provided by the embodiment of the invention, intelligent early warning and dynamic filing of the allergic reaction of the burn patient are realized, and the recognition accuracy and filing efficiency of the emergency patient in an emergency scene are remarkably improved.

The invention discloses a postoperative blackening inhibiting and brightening repairing body lotion and a preparation method thereof, the postoperative blackening inhibiting and brightening repairing body lotion comprises the following components by mass: 1-3% of tranexamic acid, 2-5% of nicotinamide, 3-6% of an aloe vera extract, 0.5-2% of menthol, 0.1-0.5% of an anti-allergy agent, 5-10% of a humectant, 2-4% of an emulsifier, 0.5-1% of a thickener, 0.05-0.2% of a pH regulator, 0.3-0.8% of a preservative, and the balance of deionized water. The invention has the following beneficial effects: by adding tranexamic acid into the formula, the activity of tyrosinase and melanocyte proliferation can be inhibited, melanin generation can be reduced from the source, nicotinamide can block melanin from being transferred to cuticle, and nicotinamide and tranexamic acid generate a synergistic effect, so that the blackness inhibition effect can be enhanced; the anti-inflammatory and moisturizing functions can be provided, then the postoperative skin inflammation reaction is reduced, menthol added in the formula can generate cooling feeling when activated, postoperative pain and scorching discomfort are effectively relieved, and the anti-allergy agent can reduce the skin allergy risk and improve the product safety.

The utility model relates to the technical field of cleaning sponge wipers and discloses a detachable cleaning sponge wiper with a handle, which comprises a sponge block, a connecting plate is adhered to the back of the sponge block, a connecting rod is in threaded connection with the right side of the connecting plate, and a connecting handle is slidably connected to the outer wall of the connecting rod. A handle is fixedly connected to the back face of the connecting plate, a hanging lug is fixedly connected to the right end of the connecting handle, a locking mechanism is arranged on the connecting handle, and a storage mechanism is arranged on the connecting plate. The connecting plate is adhered to the back of the sponge block, and the connecting rod, the connecting handle and the grip are connected onto the connecting plate, so that a user can hold the connecting handle or the grip to clean the sponge block, the hands of the user are prevented from being in direct contact with stains and cleaning agents, the skin of the hands of the user is protected, and the service life of the user is prolonged. And the health problems of skin allergy and the like caused by long-term contact with a chemical cleaning agent are reduced.

The invention relates to the field of PICC (peripherally inserted central catheter) catheterization, particularly discloses a pressure-reducing fixing device for an arm of a tumor patient after PICC catheterization, and solves the problems that the existing PICC catheterization is easy to cause local pressure pain, and a large-area application fixing mode is easy to cause symptoms such as skin stuffiness, allergy and pruritus of the patient. The device comprises an elbow guard, a PICC catheter, an outer end tube head, an oversleeve, an outer binding belt, an inner binding belt, a button base, a fixing piece, a button head, a hollow hole, a mounting box, a mounting base, a wing piece, an inserting hole, an inserting rod, a sliding groove, positioning inserting blocks, an inserting groove, a clamping assembly, an adjusting assembly and a lifting assembly, and the lifting assembly is used for lifting the PICC catheter to be isolated from the skin when the positioning inserting blocks on the two sides are far away from each other. According to the device, the outer end tube head of the PICC can be effectively stabilized, a traditional application mode is avoided, the problems of skin allergy, pruritus and the like easily caused by application and fixation of a patient are solved, meanwhile, the outer end of the PICC can be isolated from the skin, and the comfort degree is improved.

In screening cooling agents for their actions in the oral cavity, the molecule FEMA 4557, registered for use in chewing gum and hard candy, produced a long-lasting, stinging, and painful cold, like ice chips on the throat. To further study its properties, FEMA 4557 was formulated as a topical gel and shown to relieve skin discomfort without causing any skin injury or irritation. FEMA 4557 relieved inflammation from flea bites and a bumble bee sting and relieved the inflammation of dermatological disorders such as skin allergy, urticaria, and thermal injury. The duration of the anti-inflammatory action was for several hours after a single application. The pharmacological potency of FEMA 4557 did not correlate to the EC50 potency at the TRPM8 receptor. Surprisingly, when FEMA 4557 was delivered to the inflamed nasal mucosa with a compressor-nebulizer, it relieved nasal stuffiness and inhibited phlegm secretion in subjects with rhinitis, as measured by patient-outcome responses and an objective gravimetric method, respectively. FEMA 4557 was also effective for treating rhinitis when administered in nose drops or in a rinse. The effective therapeutic amount of FEMA 4557 was about 1 to 5 mg per retained dose. The conclusion is that FEMA 4557 is a potent non-irritating suppressor of acute inflammation in the nasal cavity and sinuses, a property not previously described for other topical cooling agents. Thus, FEMA 4557 and related analogs may have therapeutic utility for treating nasal inflammation and mucus hypersecretion.

The invention discloses an external traditional Chinese medicine preparation for treating skin allergy and a preparation method thereof, relates to the technical field of traditional Chinese medicine preparations, and aims at solving the problems that an existing preparation takes effect slowly, only treats skin without nourishing, and is high in irritation and poor in stability. The preparation is prepared from 200-250 g of purslane, 150-200 g of artemisia apiacea, 150-200 g of golden cypress, 100-150 g of liquorice, 80-120 g of radix ophiopogonis, 80-100 g of radix polygonati officinalis and auxiliary materials, wherein the auxiliary materials comprise a matrix, an emulsifier and the like. The preparation method comprises the steps of medicinal material pretreatment, ethanol reflux extraction, 70% ethanol and ultrasonic assistance, water extraction, extract merging, oil phase / water phase preparation, emulsification homogenization and cooling adjustment, and finally the cream with the particle size smaller than or equal to 5 microns and the pH of 6.0-7.0 is obtained. The double effects of antiallergic and skin repair are achieved, the symptom improvement rate is 42.3%-47.2% after the traditional Chinese medicine is taken for 3 days, the recurrence rate is 1.7%-8.3% after the traditional Chinese medicine is stopped for 1 month, the adverse reaction rate is 0%-3.3%, and the traditional Chinese medicine is stable after being stored for 12 months at room temperature, is suitable for multiple skin types and can be clinically and domestically used.

1. The name of the design product: electrode patch. 2. The use of the design product: prevent skin allergy and promote healing of broken skin when patients use electrocardiogram monitoring. 3. The design points of the design product: the combination of shape and pattern. 4. The picture or photo that best indicates the design points: front view.

The invention provides an old people food-based skin allergy physiotherapy moxibustion device which comprises a mounting sleeve, a protective cover and a movable plate, a side box is fixedly mounted on one side of the mounting sleeve, a threaded rod is rotatably mounted in the side box, a mounting disc is mounted on one side of the threaded rod in a threaded manner, and a moxa stick is mounted on the inner side of the mounting disc in a limiting manner. Through mutual cooperation of a threaded rod, a mounting disc, a rotating frame and a movable block, a threaded sleeve can be conveniently driven by a motor to move in the thread direction of the outer side of the threaded rod, a moxa stick can move through the threaded sleeve in the continuous combustion process, more convenience can be achieved in the use process, and the use effect is better. Meanwhile, in the moving process of the mounting disc, a movable block can slide along the inner side of a sliding groove, the mounting disc can be more stable in the moving process, the outer side of the moxa stick can be limited through a roller, the moxa stick can be guided in the moving process, and the situation of deviation in the using and fixing process is prevented.

The invention discloses application of a pediatric antipyretic composition containing radix bupleuri and cassia twig to preparation of an antiallergic drug, and relates to the technical field of medicines, the pediatric antipyretic composition containing radix bupleuri and cassia twig is prepared from radix bupleuri, cassia twig, radix puerariae, duckweed, radix scutellariae, radix paeoniae alba and cicada slough, and the pediatric antipyretic composition containing radix bupleuri and cassia twig is prepared from radix bupleuri, cassia twig, radix puerariae, duckweed, radix scutellariae, radix paeoniae alba and cicada slough. The medicine is a medicine for reducing the specific IgE (Immunoglobulin E) level and / or IgE level in serum. Experiments find that the pediatric antipyretic composition containing radix bupleuri and cortex cinnamomi has the effect of relieving passive skin allergy (PCA) reaction caused by ovalbumin, also has the effect of relieving delayed hypersensitivity (DTH) reaction caused by DNCB, and can be used as an antiallergic drug for treating allergic diseases.

The invention discloses a method for separating and preparing beta-lactam antibiotic polymer impurities. According to the preparation method of the polymer in the beta-lactam antibiotic, the polymer in the beta-lactam antibiotic can be efficiently and stably prepared and enriched, and a foundation is laid for passive skin allergy tests and in-vitro allergenicity evaluation research.

The utility model discloses a kind of jellyfish processing devices for quick cleaning and grading, it includes: shell, first screen and second screen, the upper surface of the shell is fixedly installed with stirring bucket frame, stirring bucket frame is fixedly installed on it, the inside of stirring bucket is provided with stirring assembly, the inside of the shell is provided with driving assembly and screen shaking assembly, the stirring assembly includes mounting ring and driving rod, the mounting ring is fixedly installed in stirring bucket inner side wall, the inner wall of the mounting ring is rotatably installed with cross bar, the cross bar is penetrated in the through-hole of stirring bucket side wall opening, one end of the cross bar is fixedly installed with first bevel gear, by above-mentioned structure, effectively realized by mechanical mode to jellyfish for quick cleaning and grading processing, without manual operation, prevent staff to appear skin allergy and respiratory tract disease frequent phenomenon, also improve work efficiency, use effect is good.

The invention relates to a traditional Chinese medicine composition for clearing away heat and toxic materials and cooling blood, a preparation method and application and belongs to the field of traditional Chinese medicine. The traditional Chinese medicine composition for clearing away heat and toxic materials and cooling blood comprises coptis chinensis, pulsatilla chinensis, cortex fraxini, Chinese yam, semen coicis, liquorice, codonopsis pilosula, poria cocos, plantain herb and the like, can be used for treating snake wounds, and effectively relieves snake venom symptoms and promotes body recovery through multiple effects of clearing away heat and toxic materials, relieving swelling and pain and strengthening body resistance to eliminate pathogenic factors; the traditional Chinese medicine can also be used for relieving insomnia and skin allergy symptoms, and has very good curative effects.

The utility model relates to the technical field of gastrointestinal surgery, specifically relates to a stoma nursing device for gastrointestinal surgery, including adaptation device and harness, and the harness includes left band and right band, and is installed in left and right sides of adaptation device respectively, and the front end surface of left band is equipped with first fixed part, and the rear end surface of right band is equipped with second fixed part, and the front end surface of adaptation device is skin -friendly face, and the rear end surface is mounting surface, and the adaptation device is provided with through -hole, and the mounting surface is fixedly installed with connecting pipe, and the inner wall of connecting pipe is provided with internal thread, and the inner diameter of connecting pipe is greater than the outer diameter of through -hole, and internal thread and the external thread on stoma bag match, and the outside of connecting pipe is slidably provided with sealing cover, solve the stoma bag and adopt the problem that the paste fixed, long -time wearing can cause skin allergy, red and swollen and can also exist the risk of excrement backflow when need to apply medicine to the stoma, usually adopt the cotton ball and apply, and the wound can be exposed in the air for a long time, increase the infection risk problem.

The invention relates to the technical field of traditional Chinese medicine lotions, in particular to a tendon-relaxing collateral-dredging lotion and a preparation method and application thereof. The lotion for relaxing tendons and dredging collaterals is prepared from the following raw materials: rhizoma drynariae, herba epimedii, salted eucommia ulmoides, caulis spatholobi, lycopodium clavatum, garden balsam stem, fructus trichosanthis and spina gleditsiae. The medicine composition is free of toxic traditional Chinese medicines and incompatibility, and the dosage of each medicine does not exceed the dosage specified by the pharmacopoeia standard. The traditional Chinese medicine lotion is used for treating arthralgia by using a fumigation and washing method, and has the advantages of remarkable curative effect, high safety, convenience in use and the like. The medicinal preparation is a lotion, an external treatment method is added in the clinical treatment of arthralgia, the medicinal preparation is easily accepted by patients, the medicine can be ensured to locally penetrate through the channels and collaterals of the whole body, the adverse reaction caused by excessive oral medicine is avoided, and the problem of skin allergy is not easy to occur; moreover, the operation is simple and convenient, a doctor can guide a patient to use at home, and the application range is expanded.

This invention discloses a hypoallergenic traumatic scar repair spray, belonging to the field of skin trauma repair technology. The spray, per 100mL volume, is formulated as follows: 35.0g medical-grade polydimethylsiloxane, 1.2g asiaticoside, 0.8g onion bulb extract, 0.5g allantoin, 0.6g D-panthenol, 0.3g compound sodium hyaluronate, 0.4g tocopheryl acetate, 0.2g tranexamic acid, 0.3g β-glucan, 4.0mL medical-grade glycerin, 3.0mL food-grade propanol, 0.15g carbomer 940, appropriate amount of arginine, and purified water to 100mL. This invention utilizes a multi-pathway synergistic effect, combining medical-grade silicone for hydration, centella asiatica extract for collagen remodeling, onion extract for inhibiting hyperplasia, and tranexamic acid for fading pigmentation. It effectively softens, smooths, lightens, and repairs various traumatic scars, including those from surgery, external injuries, and burns. It shows significant improvement in hypertrophic, pigmented, and old scars. This formula is free of hormones, alcohol, fragrances, preservatives, and heavy metals, avoiding common skin allergens such as peanuts, milk, seafood, and pollen. It is gentle and non-irritating, suitable for long-term use on all skin types. The spray formulation is convenient, has good penetration, and high stability, demonstrating promising prospects for industrialization and clinical application.

This invention discloses a method for synergistically relieving fracture pain through a Qi-regulating and blood-activating plaster and acupressure application, belonging to the field of integrated traditional Chinese and Western medicine orthopedic nursing. The Qi-regulating and blood-activating plaster is composed of Corydalis Rhizome, Panax Notoginseng, Angelica Sinensis, Frankincense, Myrrh, Ligusticum Chuanxiong, Salvia Miltiorrhiza, and Carthamus tinctorius in specific weight proportions, processed by vinegar-processing, ultrafine pulverization (100 mesh), and shaping with rice wine. Its preparation method includes raw material pretreatment, processing of medicinal slices, low-temperature drying, ultrafine pulverization, weighing and mixing, and preparation of the plaster before use. The application method involves preoperative assessment, followed by standardized acupressure operation along meridians until Qi is obtained, then applying the Qi-regulating and blood-activating plaster to the pain area centered on the Ashi points, and finally fixing and dynamically assessing the condition. This invention closely addresses the pathogenesis of fractures as "Qi stagnation and blood stasis, pain due to obstruction," achieving a synergistic effect of "immediate analgesia + long-term therapeutic effect." Clinical data show that the NRS score decreased by ≥3 points within 2 hours of intervention, the total effective rate was 92.5% within 7 days, the skin allergy rate was only 2.1%, and the transdermal absorption rate was 46.2%. It has the advantages of taking into account both symptoms and root causes, being safe and controllable, easy to operate, and being adaptable to individual needs. It can be operated independently by nursing staff and is suitable for all orthopedic scenarios.

The utility model discloses a ureter tractor. The ureter tractor comprises a fixed seat and a ureter body, one side of the fixing base is covered with a pressing cover base through a locking hinge mechanism, tightening pieces are arranged on the two sides of the fixing base, corresponding sliding grooves are formed in one side of the pressing cover base and one side of the fixing base, an adjusting base wraps the outer side of one end of the ureter body, and the adjusting base is arranged between the two sliding grooves in a sliding mode through a plurality of limiting pieces at the same time. And an adjusting assembly is arranged between the pressing cover seat and the adjusting seat. According to the ureter, the tensioned ureter body can be stably positioned to ensure that the ureter body is effectively dragged for a long time, so that the situation that the tensioned ureter body is separated and restores to the original shape can be prevented, and the problem of abdominal skin allergy of part of patients after being dragged for a long time can be solved; moreover, the tightness of the ureter body can be effectively adjusted, so that the problem that the patient suffers from serious urethral orifice pain and discomfort or glans penis skin damage is solved, and the comfort of the patient can be conveniently improved.

The invention relates to antimicrobial and antiviral formulation and its method of preparation thereof. The formulation acts as a disinfectant for all types of hard surfaces as well as for fogging. In particular, the disinfectant formulation of the invention comprising DDAC and copper which exhibits both anti-microbial and anti-viral activity. The disinfectant with 130× and 225× dilution with water is able to kill 100% and 98% of bacterial strain E. coli (ATCC 8739) in 10 minutes respectively. The disinfectant with dilution more than 10× shows no erythema, no edema, no inflammation and skin allergy.

The invention provides a preparation method and application of a bletilla striata polysaccharide modified nanocrystal-loaded microneedle, and the preparation method comprises the following steps: preparing andrographolide, first polyvinylpyrrolidone, polyvinyl alcohol and a first bearing liquid into a concentrated crystal suspension, and uniformly suspending andrographolide nanocrystals in the concentrated crystal suspension; mixing the concentrated and crystallized suspension and bletilla striata polysaccharide to obtain a needle solution; mixing second polyvinylpyrrolidone, glycerol and a second bearing solution to obtain a substrate solution; and putting the needle head solution and the matrix solution into a mold to form the bletilla striata polysaccharide modified nanocrystal-loaded microneedle. Experiments show that by adding the bletilla striata polysaccharide to form the needle solution, the healing rate of holes caused by puncture is effectively improved, and the risks of skin allergy and infection are avoided.

The utility model provides a male uses urine receiving bag, belongs to the medical supplies technical field, include: urine bag body, urine receiving part and fixed part, urine receiving part is used for connecting with penis, and fixed part is used for fixing urine receiving bag on patient's body, urine receiving part includes with skin contact surface, diversion layer and with urine bag contact surface, diversion layer sets up and is set up as upper sparse lower dense structure, urine one -way penetration to urine bag contact surface and lock -up through diversion layer, prevent reverse seepage. The utility model discloses through adopt soft, breathable material, improve the symptom such as skin allergy or contact dermatitis, and red, swollen, itchy of penis skin because of not breathable, improve patient's comfort, urine bag itself increase the scale, and it is convenient for medical treatment to observe patient's illness condition according to urine volume.

The utility model discloses a plaster patch for treating blood stasis swelling and pain at the initial stage of muscle strain, which comprises a plaster patch layer, a double-sided sticky layer is adhered to the side surface of the plaster patch layer, a muscle patch layer is adhered to the side surface of the double-sided sticky layer, and the plaster patch layer comprises a plaster fixing groove, non-woven fabric, a microneedle and a common intramuscular patch sticky structure. According to the muscle plaster for treating blood stasis swelling and pain in the initial stage of muscle strain, different plaster layers can be adopted for treatment for patients with different symptoms, the traditional plaster and the common muscle plaster without internal effect are combined for design, the formula is selected according to the traditional Chinese medicine syndrome differentiation and treatment principle, the treatment part is more accurate according to the trend of human meridians and collaterals, and the treatment effect is better. The traditional Chinese medicine composition not only can treat blood stasis swelling and pain at the initial stage of acute muscle strain and improve pain caused by the acute muscle strain to a human body and incapability of normal walking, but also can accelerate decomposition of lactic acid and repair of muscles by utilizing Chinese herbal medicines, and can prevent eczema or skin allergy caused by long-time closing of pores due to good air permeability.

The invention discloses a preparation method and application of centella carbon nanodots capable of inducing thyroid cancer cell B-CPAP apoptosis and resisting oxidation and relates to the field of carbon dots. The preparation method of the centella carbon nanodots comprises the steps that a centella extract is taken, ultrapure water is added to be mixed, then the mixture is transferred into a high-pressure reaction kettle with a polytetrafluoroethylene lining, a reaction is conducted for 6-8 h at the temperature of 160-180 DEG C, and the centella carbon nanodots are obtained. And cooling and filtering to obtain the centella carbon nanodots capable of inducing thyroid cancer cell B-CPAP apoptosis and resisting oxidation. The compound is used for preparing anti-thyroid cancer drugs or anti-oxidation drugs. The centella asiatica carbon nanodot prepared by the invention has a growth inhibition effect on B-CPAP cells and has an anti-thyroid cancer effect. The centella asiatica carbon nanodots also have an anti-oxidation function and a skin allergy function.

The invention belongs to the technical field of biological medicine, and particularly discloses polypeptide targeting TRPV1 and application. The polypeptide has an amino acid sequence as shown in a formula I: Asp-Gln-X1-X2-X3 (formula I), wherein X1 is selected from any one of natural or non-natural substances in Phe, Trp, His, Lys and Arg; x2 is selected from any natural or non-natural one of Phe, Trp, His, Lys and Arg; and X3 is selected from any one of natural or non-natural substances in Asn, Ser and Met. As a TRPV1 antagonist, the polypeptide is novel in structure and clear in action mechanism, has good selectivity and inhibitory activity, and can be used for developing drugs for treating diseases such as pain, xerophthalmia, pruritus and skin allergy.

The invention provides a traditional Chinese medicine spray treatment device for children's skin allergy caused by food, and relates to the technical field of medicine spray treatment devices.The traditional Chinese medicine spray treatment device comprises a shell, a connecting pipe and an atomizing head, an operation screen is arranged on the inner side of the shell, and a liquid storage box is arranged on the inner side of the shell. According to the device, a multi-channel structure is adopted, each channel independently conveys different types of liquid medicine, the independent pressure pump and the independent metering valve are arranged to adapt to different treatment requirements, the liquid medicine in each channel can be heated through the heating pipe A, it is ensured that spraying treatment is conducted on the liquid medicine at the optimal temperature, and the treatment effect and the patient comfort degree are improved; liquid medicine in different channels can be mixed according to a preset proportion through the mixing cavity, the liquid medicine is proportioned according to different skin allergy types, treatment of different people is achieved, the temperature of the liquid medicine is displayed in real time through the thermometer, a user can conveniently adjust and monitor the liquid medicine, and the uniformity and stability of the mixed liquid medicine are ensured.