The invention relates to an intelligent management system and method in the technical field of household oxygen therapy. The system comprises a household oxygen generator and heart rate and blood oxygen saturation degree monitoring equipment; the household oxygen generator is connected into the nostrils of a child patient through a nasal catheter, the heart rate and blood oxygen saturation degreemonitoring equipment comprises a finger vein oxygen monitoring probe connected with the child patient, a control valve of the household oxygen generator is provided with a control module, and a remoteclient side is connected with the control module through a network so that the oxygen flow rate or / and inspired oxygen concentration of the household oxygen generator can be remotely adjusted; the heart rate and blood oxygen saturation degree monitoring equipment comprises a data acquisition module, the data acquisition module is connected with the remote client side through the network, and real-time monitoring data is displayed on the remote client side. The system is reasonable in design, the monitoring data can be timely fed back to the remote client side of an oxygen supply system through the network, real-time control can be achieved, the fine adjustment and intelligent management of the household oxygen therapy are achieved accordingly, and the oxygen saturation degree is maintained within a reasonable range.