The invention relates to the field of pharmaceutical
chemical engineering and biological
catalysis, in particular to an electrochemical-
enzyme coupling catalysis preparation process for a Parkinson's
disease treatment
drug intermediate, the process adopts a multi-stage structure
coupling system, and the
system comprises an electro-
catalysis reaction zone, a buffer intermediate zone, an
enzyme catalysis
reaction zone and a programmable
logic control system. Wherein the electrochemical reaction area is used for regenerating an
electron transfer
mediator; the buffer middle area is used for adjusting the pH and temperature of the system, removing bubbles and removing by-products; the
enzyme catalysis
reaction zone is used for converting a substrate into a target intermediate; and the programmable
logic control system adjusts the reaction in real
time based on the monitoring result. The invention aims to realize continuous and efficient electrochemical-enzyme coupled catalytic reaction so as to prepare a target product.