5533results about "Pharmaceutical packaging" patented technology

A drug supply apparatus that packages a drug with packaging paper that is conveyed from an upstream side to a downstream side, the packaging paper being folded in half with an opening on an upper side, the drug supply apparatus including: a nozzle that dispenses the drug into the packaging paper, the packaging paper including a sealed part, in which the nozzle includes: an insertion guidance piece that protrudes downward and positions a folded part of a lower end of the packaging paper in a state of being inserted in the packaging paper from the opening on the upper side, and a posture adjustment part that guides to inside of the packaging paper the drug, and causes the drug to stand while shifting the drug toward the sealed part side in the packaging paper, the posture adjustment part being provided on the downstream side of the insertion guidance piece.

A zwitterionic polymer coating with surface grafting crosslinking, its preparation method and application are disclosed, which relate to surface modification of biomedical materials, pipelines and other medical equipment, such as extracorporeal blood circulation devices, artificial blood vessels, catheters, endoscopes and other medical equipment, to provide functions such as anticoagulation and anti-biological adhesion. The disclosure constructs the zwitterionic polymer coating with simple process and excellent performance by simulating the structure of the blood vessel intima, having the surface micro-nano structure similar to the blood vessel intima, extremely low friction coefficient, soft elasticity and super hydrophilicity, realizing zero activation and zero adhesion of blood platelets, further providing the blood circulation effect of “blood undisturbed”, which is beneficial to avoiding the problems of thrombus of artificial blood vessels in vivo, various complications caused by clinical blood extracorporeal circulation and the like, and has great clinical application value.

The invention provides a medicine dispensing machine which comprises a frame, and a medicine bottle box for storing ampoule bottles and penicillin bottles, a liquid bag box for storing liquid bags and a suction and injection device hanging frame for conveying suction and injection devices are arranged in the frame. An ampoule bottle opening device for opening an ampoule bottle, a penicillin bottle cover opening device for opening a bottle cover of the penicillin bottle, a penicillin bottle liquid medicine mixing device for mixing and uniformly shaking liquid medicine injected into the ampoule bottle, and a marking device for marking a liquid bag injected with the mixed liquid medicine are arranged in the frame; the frame is internally provided with a sucking and injecting manipulator which is used for clamping a sucking and injecting device and sucking and injecting liquid medicine of an ampoule bottle into a penicillin bottle, all the devices are transferred through a transferring manipulator, full-automatic medicine dispensing is carried out, and the medicine dispensing efficiency is improved.

A support device for supporting a plurality of containers for pharmaceutical use to be handled in a processing line includes a plate having a plurality of first housing seats, wherein each first housing seat includes a first end edge defining an opening; and a base within each first housing seat, wherein the base includes at least one stacking element protruding above the first end edges of the first housing seats.

A tamper evident seal structure for a vial septum or other cover having a housing including a sidewall terminating in oppositely disposed open and closed ends. A retainer is fixedly disposed within the housing and structured for retaining engagement with a portion of a vial, substantially adjacent the vial cover. The housing also includes a pressure member disposed within an interior thereof in attached, relation to the closed-end. The pressure member and the retainer are cooperatively disposed and structured to respectively exert pressure on the vial cover concurrent to retaining engagement with the vial. Tamper evident capabilities are at least partially defined by a detachment of a removable sidewall section from a remainder of said sidewall.

A childproof pill container has a top lid, an upper lid, a box body, a bottom lid, and a childproof lock. The upper lid is movably mounted below the top lid and has a first through hole. The box body is mounted below the upper lid and has a second through hole. The bottom lid is mounted below the box body and has a third through hole. The childproof lock includes a rotatable member and an accessory. The rotatable member is mounted through the first through hole, the second through hole and the third through hole and contact the top lid. The rotatable member comprises a first block. The accessory comprises a first opening corresponding to the first block. When the first block is aligned with the first opening, the rotatable member can move upwardly to push the top lid, so the childproof pill container can be opened.

A pill container has a body, at least one lid, and at least one elastic assembly. The body comprises a first wall, a second wall, and at least one compartment. The first wall and second wall are two opposite sides of the body. The compartment is located between the first wall and the second wall. The lid is pivotably mounted on the second wall of the body. The elastic assembly is located on the second wall, and has a flexural segment and a first protruding section. The first protruding section is located on the flexural segment and contacts the second wall. The first protruding section supports a space between the flexural segment of the elastic assembly and the body.

A quick-fill pill organizer has a box, multiple retrieving covers, and a packaging cover. The box has multiple compartments. Each compartment has a retrieving opening and a packaging opening. The retrieving cover is mounted on the retrieving opening and corresponds to the compartment one-to-one such that the corresponding compartment connects to or is blocked from the outside. The packaging cover is mounted on the packaging openings such that all the compartments connect to or are blocked from the outside at the same time. When the retrieving openings are upward, the retrieving cover of the specific compartment can be opened. When the packaging openings are upward, the packaging cover can be opened or closed such that all of the compartments connect to or are blocked from outside at once.

The invention provides an anticoagulant coating for medical instruments, which can be used in the field of regenerative medical instruments. The prepared anticoagulant coating has short-term and long-term anticoagulant performance, and in addition, the thrombin responsive nanoparticles wrapped in the hydrogel coating can selectively release a factor Xa (FXa) inhibitor apixaban according to needs, so that thrombosis is inhibited in the middle stage of implantation. In-vitro and in-vivo experimental evidences show that after the material is implanted for a long time, an organized endodermis can be seen on the surface of the material, and the material has a special antithrombotic characteristic. The dynamic adjusting system has a multi-layer protection mechanism, and a new thought can be provided for designing the surface of a contact blood material adapting to environmental conditions.

The invention belongs to the field of biological medicine, and particularly relates to application of recombinant III-type humanized collagen in an injection. The invention provides an injection, the injection comprises recombinant III-type humanized collagen, the amino acid sequence of the recombinant III-type humanized collagen comprises n repetitions of the sequence as shown in SEQ ID NO.1, n is an integer greater than or equal to 1, and when n is an integer greater than or equal to 2, the repetitions are directly connected; moreover, when the injection is applied in one application period, the total application amount of the recombinant III-type humanized collagen is less than or equal to 3640 mg / kg. The recombinant III-type humanized collagen has high-dose injection safety, and can be applied in a single high-dose manner or continuously applied to realize high-dose application in a total amount level.

The invention relates to the technical field of coating surface preparation, in particular to an anticoagulant coating based on novel tick-derived anticoagulant protein Qinghaenin and a preparation method of the anticoagulant coating. The functional layer of the anticoagulant coating comprises the following components: anticoagulant protein Qinghaenin or a functional peptide fragment Qinghaenin 167-192 of the anticoagulant protein Qinghaenin, wherein the amino acid sequence of the functional peptide fragment is as shown in SEQ ID NO. 2. The preparation method of the anticoagulant coating comprises the following steps: by using a polydopamine coating as a substrate layer, covalently grafting through an amido bond, immobilizing anticoagulant protein Qinghaenin capable of inhibiting FXII factor activation or a functional peptide fragment Qinghaenin 167-192 thereof on the surface of a medical polymer material, and successfully constructing a novel anticoagulant coating. Compared with an unmodified medical polymer material, the modified coating can significantly enhance the hydrophilic performance of the material and inhibit platelet adhesion and activation, finally effectively prolongs the in-vitro blood coagulation time, and shows excellent anticoagulation performance.

The invention discloses a portable field multifunctional medical instrument, and relates to the technical field of medical instruments, the portable field multifunctional medical instrument comprises a shell with a Y-shaped cross section, a main frosted knife abutting against an ampoule bottle opening is arranged at the middle position of the shell, and a curved plate located above the main frosted knife is arranged at the middle position of the shell; a driving assembly used for driving the curved plate to move to impact the tip end of an ampoule bottle to achieve shell ejection is arranged in the shell, a bottle opening groove used for opening an aluminum cap bottle is formed in the lower surface of the shell, and the bottle opening groove is composed of a plurality of sections of curved surfaces of different sizes. The device integrates the multiple functions of bottle opening, marking, horizontal positioning, guiding and the like, medical staff can achieve various operations by taking the device without repeatedly finding and taking various medicine related tools in a first-aid kit, the time of the medical staff is saved to a certain degree, and the life rescue efficiency is improved.

The present disclosure provides an electronic medicine box with a medicine cup and its usage method. The electronic medicine box with a medicine cup includes a housing, a cellular tray, a connecting assembly, a plurality of medicine cups, a driving mechanism, and a lifting mechanism. The housing is provided with a medicine taking port. The cellular tray is provided with a plurality of placement slots that are configured for accommodating the plurality of medicine cups. The cellular tray is rotatably disposed inside the housing through the connecting assembly, and is provided with the driving mechanism that is configured for rotating the cellular tray. The lifting mechanism is configured for pushing the medicine cup out of the placement groove towards the medicine port. The electronic medicine box with the medicine cup further includes a first infrared sensor, a camera, and a first sensing element.

The present disclosure relates to a container assembly including a multi-chamber container that fits within a protective outer sleeve. The container includes covers for allowing the chambers to be individually accessed. The container includes an integrated retention arrangement that allows the container to be secured within the outer sleeve in a manner in which unintended longitudinal movement between the outer sleeve and the container is prevented.

A container for organized storage and selective accessibility of items, such as medications. The container includes a base with a base plate and a central base hub, supporting the plurality of pill cases, each with a truncated sector shape and partitioned into two compartments accessible from opposing ends. The container incorporates a magnetic coupling system, comprising a plurality of primary magnetic elements on the base hub and a plurality of secondary magnetic elements on the pill cases, thereby enabling each pill case to attach to the base in one of two orientations, providing access to either compartment.

A vial adapter comprises an adapter body comprising a top wall and a sidewall projecting from the top wall in a longitudinal direction to form a receptacle with a distal side of the top wall. The receptacle is configured to receive at least a portion of a barrel head of an injection vial. A movable part comprises a base part and a spike fixed to the base part. The spike extends through the top wall in a distal direction into the receptacle. An actuating member is mechanically coupled to the movable part, and is movable relative to the adapter body from a start position to an end position along a first direction to induce a distally directed displacement of the movable part relative to the adapter body. The mechanical coupling between the movable part and the actuating member is releasable when the actuating member is in the end position.

A dispensing device for dispensing a beneficial agent configured to transition between an inactive state and an active state. The dispensing device can include a body, a pressure chamber, a primary container, and / or a diaphragm. The pressure chamber and diaphragm may both be disposed within the body, and the primary container may be disposed within the pressure chamber and engaged with the diaphragm. The primary container may include a distal end with a septum or pierceable fitment disposed on a distal side of the diaphragm. The dispensing device may be configured to transition between an inactive state and an active state when a pressurized fluid is provided to the pressure chamber by moving the primary container distally against the diaphragm to cause the diaphragm to deform, including stretching a section of the diaphragm in a distal direction.

A vessel including a thermoplastic wall enclosing a lumen is disclosed. The wall supports an SiOx composite barrier coating or layer, for which x is from 1.8 to 2.4, between the wall and the lumen. High Resolution X-ray Photoelectron Spectroscopy (XPS) shows the presence of an interface between the composite barrier coating or layer and the wall or substrate. In one aspect, the interface has at least 1 mol. % O3—Si—C covalent bonding, as a proportion of the O3—Si—C covalent bonding plus SiO4 bonding. In another aspect, the interface has an Si 2p chemical shift to lower binding energy (eV), compared to the binding energy of SiO4 bonding. The result is a tightly adherent composite barrier coating or layer having a high degree of adhesion to the substrate under practical use conditions. Methods of applying the composite barrier coating or layer are also disclosed.

A container system with a recordable device having a substantially unaltered packaging profile when compared to standard commercially available prescription containers. The container includes a bottle having a cylindrical body having a length greater than its width. A cap is provided with an inclined spiral or helical land and stops to permit it to be affixed to the container. The cap is equipped with a snap fit ring or a fitting on its underside. A recording device is configured with a land or snap ring removably engageable with the snap fit ring on the underside of the cap. The cap has an aperture to accommodate a recording switch on the recording device. The cap is provided with a speaker switch aperture to permit the user to activate the message on the recording device to hear about the contents of the bottle.

A medicine refrigeration cup with a portable medicine box is provided, which includes a cup body, a refrigeration device, a hanging ring, and a medicine box. The cup body includes a cup main body and a cup cover, the refrigeration device is provided in the cup cover, the hanging ring includes a ring-shaped member sleeved on the cup main body and a first hanging groove protruding from one side of the ring-shaped member. The first hanging groove includes a first outer groove wall. The medicine box includes a second medicine compartment, and an end portion provided at one axial end of the second medicine compartment. The end portion includes a second hanging groove. The second hanging groove includes an open end, a closed end, and a second outer groove wall. The second outer groove wall is inserted into the first hanging groove.

Some embodiments disclosed herein relate to a device for transferring precise amounts of fluid from at least one source container to at least one target container. In some embodiments, the fluid is first transferred from the source container (e.g., a vial) through a connector to an intermediate measuring container (e.g., a syringe). In some embodiments air can pass through an air inlet and enter the vial to compensate for the volume of fluid withdrawn from the vial. An air check valve or a bag or a filter can prevent the fluid from escaping through the air inlet. The precisely measured amount of fluid can then be transferred from the intermediate measuring container to the target container (e.g., an IV bag). In some embodiments the connector can include a source check valve and a target check valve to direct fluid first from the source container to the intermediate measuring container and then from the intermediate measuring container to the target container. Some embodiments of the device can include a motor and a controller for automatically actuating a plunger of the syringe to transfer the desired amount of fluid.

A system and method is described for printing a label with an RFID tag. The system includes an RFID reader that queries a first RFID tag coupled to a first medicinal container that includes a medication. In response, the system receives a first unique identifier and uses the first unique identifier to determine a status of the medication, associate the first medicinal container with a medical provider and print a second label that includes a second RFID tag for a second medicinal container.

To provide: a method for producing an anti-thrombogenic material in which white turbidity is reduced; a method for producing a medical instrument coated with the anti-thrombogenic material produced by the method; and an anti-thrombogenic material in which white turbidity is reduced.SOLUTION: A method for producing an anti-thrombogenic material according to the present invention comprises a step of copolymerizing a specific alkyl (meth)acrylate, a silicone (meth)acrylate, and an alkoxy polyethylene glycol (meth)acrylate, wherein the silicone (meth)acrylate used here has a weight average molecular weight of 1450 or less.SELECTED DRAWING: None

The invention provides a clean air main machine with a dispensing device storage bin and a pneumatic dispensing system.The clean air main machine comprises a machine shell, an air source device and an air filtering device are installed in the machine shell, an air outlet port is formed in the machine shell, and the air source device is connected with the air outlet port through the air filtering device; the air outlet end opening is connected with the air inlet end of the medicine dispensing device, a containing bin used for containing the medicine dispensing device is formed in the machine shell, and sterilization equipment is arranged in the containing bin. Before the dispensing device is used, the dispensing device can be placed in the storage bin of the clean air main machine, the sterilizing device in the storage bin is used for sterilizing the dispensing device, the sterilized dispensing device is stored in the storage bin, and bacteria in air are prevented from entering and adhering to the dispensing device to cause pollution.

A system having a first locking medication dispenser and a second locking medication container both connected to a base. Each of the first locking medication dispenser and the second locking medication dispenser has an outer container, a inner container configured to be disposed within the outer container and further configured to receive a medication, and a rotatable assembly connected to a bottom of the inner container, the rotatable assembly having a hole defined therein, wherein the hole rotates with the rotation of the rotatable assembly. The base is coupled to the first locking medication dispenser and the second locking medication dispenser and the base is configured to dispense medications from either of the first locking medication dispenser or the second locking medication dispenser.