28 results about "Glass Vial" patented technology

A method for improving the efficiency of a pharmaceutical filling line by running the filling line at an increased throughput rate is disclosed. The method involves using glass vials that have been strengthened and coated to reduce the coefficient of friction of the outer surface of the vials with a pharmaceutical filling line set at a rate greater than or equal to 600 vials per minute and running in an efficiency of at least 70%.In other embodiments of the invention, the pharmaceutical filling line may also be provided with a polymer chemical coating at points of contact with the glass vials, thereby further reducing the friction between the vials and the points of contact and the effects of impact of the vials with contact points of the pharmaceutical filling line.

This invention belongs to the field of veterinary drugs and discloses a method for preparing difloxacin suspension injection, comprising the following steps: Step 1: Difloxacin is added to an aqueous solution containing gluconolactone to prepare a difloxacin solution; Step 2: A crystallization inhibitor is added to the difloxacin solution in Step 1; Step 3: The solution is dispensed into glass vials for injection, sealed, and sterilized with high-temperature steam; Step 4: The sterilized injection solution is immediately subjected to cold water immersion or cooled to room temperature in air for leak testing and crystallization, simultaneously obtaining difloxacin injection solution. Based on previous research results, this invention further proposes that, in the further optimization process, gluconolactone is used as a co-solvent for difloxacin, dissolved by heating, dispensed into injection bottles, sterilized at high temperature, and then recrystallized after cooling to obtain a suspension with small crystal particle size. This process is suitable for large-scale production.

This invention discloses a fully automated sample pretreatment system for liquid addition, extraction, and filtration, belonging to the field of chemical analysis pretreatment technology. Addressing the problems of low efficiency, health risks, and information confusion associated with manual operation in existing technologies, this invention provides a solution, comprising: a first multi-dimensional robotic arm working in conjunction with a first scanning device to automatically scan, open, and add liquid to sample tubes; a second multi-dimensional robotic arm to move the sample rack, after liquid addition, into an ultrasonic water bath for extraction and then remove it; a three-axis moving mechanism integrating a third gripper and a syringe clamping module to complete secondary scanning, opening, aspiration, filter installation, pressure filtration, and the coding, opening, and closing of glass vials; and a controller coordinating the collaborative work of all components. This invention is mainly used for sample pretreatment in chemical analysis laboratories, achieving full automation of the liquid addition, extraction, and filtration process, improving processing efficiency and sample information traceability.

The invention relates to boroaluminosilicate glass with excellent visual appearance and a method for producing the glass. The invention also relates to the use of such a glass, in particular for pharmaceutical packaging, for example for pharmaceutical containers such as glass vials, glass ampoules, glass cartridges or glass syringes or the like.

The utility model relates to medical packaging detection equipment technical field discloses a kind of automatic glass medicine bottle lamp inspection machines, in the device, through bevel gear and sprocket, transmission chain cooperation, the power of driving motor is efficiently transmitted to each transmission cylinder, the stable transmission of glass medicine bottle is realized.Detection light source and reflector in detection shell provide good illumination condition for detection, enhance detection effect, ensure that the impurities in the inside of medicine bottle can be accurately detected, the accuracy and reliability of detection are significantly improved, and at the same time, through the design of spacing adjusting assembly, especially the cooperation of upper positioning pin and sliding block, the spacing between transmission cylinders can be flexibly adjusted, so as to adapt to glass medicine bottles of different sizes.This core technology effectively improves the versatility and application range of the equipment, reduces the equipment adjustment time and cost caused by the change of medicine bottle specifications.

This invention belongs to the field of iodine adsorption material technology, and discloses a method for synthesizing and applying a highly efficient iodine adsorption material. The synthesis method includes: S1, adding an organic aldehyde ligand to a container, adding a solvent, and stirring to completely dissolve the aldehyde ligand; S2, slowly adding the above solution dropwise to an organic amine ligand solution to completely mix it with the amine ligand; S3, sealing the above mixed solution and stirring at room temperature until the color deepens; S4, after the reaction is complete, separating the reaction solution into small glass vials, tightening the caps, loosening them by half a turn, and placing them in a protective atmosphere; after several days of gas-liquid diffusion, visible crystals form at the bottom of the glass vials. The synthesized adsorption material has applications in volatile and radioactive iodine. The crystalline adsorption material synthesized by this invention has good stability, high adsorption efficiency for iodine, and a fast adsorption rate, and can be used for nuclear waste treatment and the capture of radioactive iodine.

The present invention provides a method for preparing a ternary nanomaterial. A lithium source, nickel salt, cobalt salt, and manganese salt are mixed and ground to obtain A. A is transferred to a glass vial and added to another open vial containing 1 ml of distilled water. After reaction in an oven, the vial is removed, dried at the same temperature, and then reground to obtain B. B is calcined to obtain a ternary powder. The ternary powder is placed in a vacuum tube furnace, with a polycrystalline sapphire substrate positioned in the relatively low-temperature area downstream of the furnace. The furnace is heated, and the pressure is increased to 100 Torr within 1 minute and maintained for 0.5 to 1 hour. The system temperature is raised to a specified set point. Argon gas is passed through the system. After reaction, the system is cooled to room temperature to obtain the final product. The ternary nanomaterial prepared by combining wet solid phase and thermal evaporation methods exhibits a large specific surface area and improved electrochemical performance. The initial discharge capacity is 177 mAh / g, and after 50 cycles, the discharge capacity is 169 mAh / g, with a capacity retention rate of 95.5%.

The embodiment of the invention discloses a CQDs-coated HOF-101 composite microcrystal as well as a preparation method and application thereof, relates to the technical field of photocatalytic materials, and aims to solve the technical problem that an existing photocatalytic material is relatively low in light utilization rate. The preparation method of the CQDs (at) HOF-101 composite microcrystal comprises the following steps: uniformly dissolving HOF-101 micromolecule 1, 3, 6, 8-tetra (4-carboxybenzene) pyrene in a polar aprotic solvent, filling the solution and carbon dots into a small glass bottle through an organic filter membrane, uncapping the small bottle, placing the small bottle into a beaker filled with an alcohol solvent, and after the alcohol solvent enters the organic solvent, adding the organic filter membrane into the beaker, so as to obtain the CQDs (at) HOF-101 composite microcrystal, namely the CQDs (at) HOF-101 micromolecule 1, 3, 6, 8-tetra (4-carboxybenzene) pyrene. And after crystals grow out, centrifuging to obtain precipitates, and washing the precipitates to obtain the CQDs (at) HOF-101 crystals.

A method for improving the efficiency of a pharmaceutical filling line by running the filling line at an increased throughput rate is disclosed. The method involves using glass vials that have been strengthened and coated to reduce the coefficient of friction of the outer surface of the vials with a pharmaceutical filling line set at a rate greater than or equal to 600 vials per minute and running in an efficiency of at least 70%. In other embodiments of the invention, the pharmaceutical filling line may also be provided with a polymer chemical coating at points of contact with the glass vials, thereby further reducing the friction between the vials and the points of contact and the effects of impact of the vials with contact points of the pharmaceutical filling line.

The present invention provides a preparation method, product and application of a zinc oxide / silver molybdate nanophotocatalytic material. The method includes: fully mixing a molybdenum source, silver oxide and a zinc salt according to a stoichiometric molar ratio and grinding them in a mortar to obtain A; transferring the obtained mixture to a 20-milliliter glass vial, adding another 3-milliliter open vial containing 1 milliliter of distilled water therein; then, after reacting the whole container in an oven at 70-80 °C for 24-30 h, taking out the water vial, drying it at the same temperature for 12-18 h and then re-grinding to obtain B; placing B in a muffle furnace and calcining it at a heating rate of 1-2 °C / min to 350-500 °C for 2-4 h to obtain the final product, i.e., the zinc oxide / silver molybdate nanophotocatalytic material. After the adsorption of methyl orange reaches equilibrium in the dark first, under the condition of ultraviolet photocatalysis, after 60 min, the degradation of methyl orange reaches 99.6%.

The present invention relates to a method for the production of a liquid formulation suitable for intravenous administration in a glass vial with a rubber stopper, where the formulation is dexmedetomidine hydrochloride in water for injection (WFI). The method comprises steps of introducing WFI into a preparation vessel, passing an inert gas through the WFI until a dissolved oxygen content of 1 ppm or less is obtained, adding and dissolving a quantity of sodium chloride and dexmedetomidine hydrochloride, filtering the dexmedetomidine hydrochloride solution, and filling one or more glass vials with the liquid dexmedetomidine hydrochloride-in-WFI formulation before closing said vials with a rubber stopper and sealing the vials. The invention also relates to a sterile liquid formulation of dexmedetomidine hydrochloride in WFI, and its applications.

Disclosed herein are glass pharmaceutical vials having sidewalls of reduced thickness. In embodiments, the glass pharmaceutical vial may include a glass body comprising a sidewall enclosing an interior volume. An outer diameter D of the glass body is equal to a diameter d1 of a glass vial of size X as defined by ISO 8362-1, wherein X is one of 2R, 3R, 4R, 6R, 8R, 10R, 15R, 20R, 25R, 30R, 50R, and 100R as defined by ISO 8362-1. However, the sidewall of the glass pharmaceutical vial comprises an average wall thickness Ti that is less than or equal to 0.85*s1, wherein s1 is a wall thickness of the glass vial of size X as defined by ISO 8362-1 and X is one of 2R, 3R, 4R, 6R, 8R, 10R, 15R, 20R, 25R, 30R, 50R, and 100R as defined by ISO 8362-1.

The present application is directed to glass containers with increased bottom thickness. The glass containers disclosed herein have a bottom with an increased thickness compared to conventional glass containers. Due to the thermal insulating properties of glass, the greater thickness of the bottom of the glass vials slows down the heat transfer rate through the bottom so that the heat transfer rate through the bottom of the glass vial is the same as or less than the heat transfer rate through the sidewalls of the glass vial. This in turn provides for more even cooling of the contents of the glass vial, which results in formation of smaller crystals during crystallization and reduces concentration gradients throughout the composition.

The invention provides a methylthio-modified Ce-MOF used as an electrode sensing material, which can be used for single and simultaneous electrochemical analysis and detection of heavy metal ions such as Cd < 2 + >, Pb < 2 + >, Cu < 2 + >, Hg < 2 + > and the like. The method comprises the following steps: weighing ceric ammonium nitrate, methylthio terephthalic acid and acetic acid in a small glass bottle, dissolving in DMF (Dimethyl Formamide), stirring for 15 minutes, transferring the mixed solution into a round-bottom flask, and reacting in an oil bath pan at 35 DEG C for 24 hours to form a yellow solution; and centrifugally collecting the product, washing with ethanol and acetone, and finally drying in vacuum to obtain the methylthio-modified Ce-MOF electrode material which is yellow solid powder. The fluorescent probe has high selectivity and sensitivity for independently and simultaneously detecting Cd < 2 + >, Pb < 2 + >, Cu < 2 + > and Hg < 2 + > ions, and can also be applied to detection of real samples.

A protective sleeve apparatus for multiple vial carriage, said apparatus comprising: a pliable enclosure (sleeve), wherein said sleeve is comprised of a first surface, second surface, and at least three side walls adjoining the first surface with the second surface to form the sleeve; at least one aperture disposed on at least one of the first and / or second surface of the sleeve, wherein said aperture is configured for an insertion or removal of the glass vial into the sleeve; and at least one means of interlocking the sleeve with at least a second sleeve, wherein the interlocking component is disposed on at least one of the side walls of either of the two sleeves, whereby the interlocked sleeves enable protective multiple vial carriage.

The invention discloses a Co-MOF (Metal Organic Framework) material based on 1-aminobenzene-3, 4, 5-tricarboxylic acid as well as a preparation method and application of the Co-MOF material. The invention discloses a preparation method of cobalt acetate. The preparation method comprises the following steps: sealing a mixture of 4, 4 '-azobipyridine, acetonitrile and water in a 10mL small glass bottle, carrying out a hydrothermal reaction, adding a mixture of 1-aminobenzene-3, 4, 5-tricarboxylic acid and water, stirring, adjusting the pH value to 9, continuing to carry out a sealed reaction for 24 hours, cooling to room temperature, washing, and drying to obtain the high-crystallinity Co-MOF material. The preparation method is simple and feasible. The Co-MOF material has good friction power generation performance and stability, and when the Co-MOF material is applied to a vertical contact separation type friction nanometer generator and water pollution treatment, the device can efficiently degrade 98.8% of methylene blue within 90 minutes under the working condition of 5Hz.

Disclosed herein are glass pharmaceutical vials having sidewalls of reduced thickness. In embodiments, the glass pharmaceutical vial may include a glass body comprising a sidewall enclosing an interior volume. An outer diameter D of the glass body is equal to a diameter d1 of a glass vial of size X as defined by ISO 8362-1, wherein X is one of 2R, 3R, 4R, 6R, 8R, 10R, 15R, 20R, 25R, 30R, 50R, and 100R as defined by ISO 8362-1. However, the sidewall of the glass pharmaceutical vial comprises an average wall thickness Ti that is less than or equal to 0.85*s1, wherein s1 is a wall thickness of the glass vial of size X as defined by ISO 8362-1 and X is one of 2R, 3R, 4R, 6R, 8R, 10R, 15R, 20R, 25R, 30R, 50R, and 100R as defined by ISO 8362-1.

The invention belongs to the technical field of iodine adsorption materials, and discloses a synthetic method and application of a high-efficiency iodine adsorption material, the synthetic method comprises the following steps: S1, adding an organic aldehyde ligand into a container, adding a solvent, and stirring to completely dissolve the aldehyde ligand; s2, slowly dropwise adding the solution into an organic amine ligand solution, and completely mixing the organic amine ligand solution with an amino ligand; s3, sealing the mixed solution, and stirring at room temperature until the color becomes dark; s4, after the reaction is completed, distributing reaction liquid into a small glass bottle, tightening a bottle cap, unscrewing a half circle, and placing the small glass bottle in a protective atmosphere; after the gas liquid diffuses for several days, macroscopic crystals are formed at the bottom of the small glass bottle. The adsorption material obtained through synthesis is applied to volatile and radioactive iodine. The crystalline adsorption material synthesized by the method is good in stability, high in iodine adsorption efficiency and high in adsorption rate, and can be used for nuclear waste treatment and radioactive iodine capture.

This application discloses CQDs@HOF-101 composite microcrystals, their preparation method, and applications, relating to the field of photocatalytic materials technology, aiming to solve the technical problem of low light utilization rate of existing photocatalytic materials. The preparation method of the CQDs@HOF-101 composite microcrystals includes the following steps: HOF-101 small molecule 1,3,6,8-tetra(4-carboxyphenyl)pyrene is uniformly dissolved in a polar aprotic solvent, and then, along with carbon dots, is placed in a glass vial through an organic filter membrane. The vial is then placed in a beaker containing an alcohol solvent. After the alcohol solvent enters the organic solvent and crystals grow, the crystals are centrifuged to obtain a precipitate. The precipitate is then washed to obtain CQDs@HOF-101 crystals.

The invention provides a preparation method of a copper-loaded magnesium vanadate material and a product and application of the copper-loaded magnesium vanadate material. Vanadate, magnesium salt and copper salt are fully mixed according to the stoichiometric molar ratio and ground in mortar, and A is obtained; transferring the obtained mixture into a 10ml glass vial, adding another 2ml open vial containing 1ml of distilled water, keeping the whole container in an oven at 70-80 DEG C, reacting for 24-30 hours, taking out the vial, drying at the same temperature for 8-10 hours, and regrinding to obtain B; and putting the B into a muffle furnace, heating to 400-600 DEG C at a heating rate of 1-2 DEG C / min, and calcining for 2-4 hours to obtain a final product, namely the copper-loaded magnesium vanadate material. Under the condition of 1 A / g current density, the first specific discharge capacity is 268.8 mAh / g, after 100 cycles, the specific discharge capacity is 248.8 mAh / g, and the capacity retention ratio is 92.6%.

A method for producing a glass article from a glass tube includes rotating a glass tube about a central axis, heating a target region of the glass tube to a forming temperature, forming at least one feature of the glass article at the target region of the glass tube, and separating the glass article from a working end of the glass tube. Heating the target region of the glass tube, separating the glass article from the working end of the glass tube, or both, includes exposing the target region, separation region, or both of the glass tube to a laser beam generated by a laser system, which heats the glass tube at the target region, separation region, or both. A system includes a converter and the laser system for heating the glass tube or separating the glass article from the glass tube.

The utility model discloses a glass medicine bottle lamp detection device belongs to medicine packing detection equipment technical field. The device includes workstation surface, and the feeding mechanism, transmission mechanism, lamp detection mechanism and the material collecting mechanism are sequentially arranged on the workstation surface. The lamp detection mechanism includes the rectangular lamp board and the magnifying glass of symmetrical layout at transmission mechanism both sides, and the center connecting line of rectangular lamp board and magnifying glass is perpendicular with the axis direction of transmission mechanism. The feeding mechanism is the feeding box of top opening, and the material collecting mechanism is the material collecting box of top opening, and transmission mechanism includes the guardrail of transmission belt and setting at both sides, and the transmission belt both ends are provided with driving wheel and driven wheel respectively, and the driving wheel axle is connected with servo motor. The start -stop switch of controlling transmission mechanism start -stop is arranged on the support below workstation. The utility model discloses through mechanization transmission and auxiliary lighting detection, has improved glass medicine bottle detection efficiency, has reduced the labor intensity of worker, has solved the problem of low efficiency of traditional manual handheld magnifying glass detection mode.

The present invention provides a glass vial for medical use, which is provided with an opening, a mouth portion, a shoulder portion, and a chamber to be filled. The glass vial is characterized in that: the vial has a thin film layer on at least a portion of the inner wall surface; the chamber to be filled has a side surface portion and a bottom surface portion; the thickness of the thin film layer in the bottom surface portion is 5-150 times thicker than the thickness of the thin film layer in the side surface portion; and the average thickness of the thin film layer in the bottom surface portion is 100-5000 nm.

The present invention relates to methods of treating Atopic Dermatitis in a human subject comprising administering a therapeutically effective amount of an anti-OX40L antibody, or antigen-binding fragment thereof, wherein the antibody or fragment thereof is administered via injection. Also provided are anti-OX40L antibodies, or antigen-binding fragments thereof, glass vials, drug delivery devices, prefilled syringes, microinfusors, pen delivery devices, autoinjectors and kits comprising an anti-OX40L antibody, or antigen-binding fragment thereof for use in such methods.

The utility model discloses glass medicine bottle stacking equipment which comprises a machine frame, a stacking chain plate mechanism is arranged on the machine frame, a bottle stacking frame and a bottle pushing frame which slide in the direction perpendicular to the conveying direction of the stacking chain plate mechanism are arranged on the machine frame and above the stacking chain plate mechanism, a sliding seat is arranged on the bottle stacking frame, and the bottle pushing frame is arranged on the sliding seat. A switching cylinder for driving the sliding seat to move is arranged on the bottle stacking frame, and a bottle separating seat and a resetting cylinder for driving the bottle separating seat to move up and down are movably arranged on the sliding seat; at least three bottle separating plates are arranged on the bottle separating seat in parallel, and a channel for accommodating a single row of glass medicine bottles is arranged between every two adjacent bottle separating plates; a middle conveying chain plate mechanism is arranged beside the stacking chain plate mechanism on the rack, the upper surface of the middle conveying chain plate mechanism is lower than the stacking chain plate mechanism, the conveying direction of the middle conveying chain plate mechanism is perpendicular to the stacking chain plate mechanism, and a lifting base and a lifting power device driving the lifting base to move are arranged on the discharging side of a middle conveying chain plate on the rack. The lifting seat is provided with a pair of tray discharging chain mechanisms which are used for stacking the trays containing the medicine bottles and then sending out the trays.

The present invention relates to a dermal filler for soft tissue augmentation comprising 85-99% water and 1-12% microbial cellulose wherein the said cellulose is Acetobacter xylinum fermented in coconut milk culture media. The microbial cellulose is reduced to a nano particle having a diameter predominantly 100 nm and has a nano porous mesh structures and fibrils aggregate forming tunnels in between the microbial cellulose fibers for gaseous and fluid exchange; has a high cellulose crystallinity (60-80%) and has an enormous mechanical strength for the extended biodegradability, and biocompatibility. Said microbial cellulose has a preservative in the form of a natural coconut derived active ingredient where monolaurin is present in the amount of 1%. It is pure, natural, hydrophilic and characterized by the absence of lignin. It can be easily injected and pass through a gauge 30 needle with minimal reaction and discomfort at the site of the injection. It is safe and has a porosity benefit which makes it more permeable and penetrable for effective tissue augmentation and aesthetic correction of wrinkles or loss of muscle volume including nasolabial furrow, wrinkled cheeks, deep smile lines and lipoatrophy correction. It is non¬ phototoxic, no toxicity and safe on the area around the eyes (Optisafe). It can be administered intradermally or sub-epidermally. The cellulose suspension is packed in glass vials of 3 ml, 8%, 10% and 12% concentration.

An aluminoborosilicate glass with excellent visual appearance, and a method of producing such glass are provided. The use of the glass, in particular for pharmaceutical packaging, for example pharmaceutical containers such as glass vials, glass ampoules, glass cartridges or glass syringes.