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42 results about "Microbial adhesion" patented technology

Microbial adhesion to surfaces is the onset of the development of a biofilm. Biofilm formation occurs on all surfaces exposed to an aqueous environment, such as soft tissues, implanted biomaterials or tooth surfaces in the human body, rocks in rivers, pipelines in water works, and on ship hulls (51).

Implantable or insertable medical device resistant to microbial growth and biofilm formation

InactiveUS6887270B2Prevent preferential partitioningPrevent chemical modificationAntipyreticAnalgesicsActive agentMicrobial adhesion
Disclosed are implantable or insertable medical devices that provide resistance to microbial growth on and in the environment of the device and resistance to microbial adhesion and biofilm formation on the device. In particular, the invention discloses implantable or insertable medical devices that comprise at least one biocompatible matrix polymer region, an antimicrobial agent for providing resistance to microbial growth and a microbial adhesion / biofilm synthesis inhibitor for inhibiting the attachment of microbes and the synthesis and accumulation of biofilm on the surface of the medical device. Also disclosed are methods of manufacturing such devices under conditions that substantially prevent preferential partitioning of any of said bioactive agents to a surface of the biocompatible matrix polymer and substantially prevent chemical modification of said bioactive agents.
Owner:BOSTON SCI SCIMED INC

Non-leaching surface-active film compositions for microbial adhesion prevention

Surface-active, non-leaching antimicrobial film forming compositions and methods for their application to preferably medical device surfaces are provided. The compositions form durable coatings with long-lasting antimicrobial efficacy without formation of a zone of inhibition. Optionally the films can be hydrophilic. Specific long-chain molecules of certain chemical reactivity are covalently bonded into a polymeric matrix. They maintain a long-term anti-microbial efficacy without being leached out into the aqueous environment. The polymeric matrix of the compositions contain functional groups, which covalently bond to an amine, thiol, carboxyl, aldehyde or hydroxyl active group of selected long chain quaternary ammonium compounds. Upon formation of a covalent bonding with the polymeric matrix the long chain compounds become immobilized but still maintain antimicrobial efficacy. They do not leach out over extended period of time into the aqueous environment and maintain an anti-microbial efficacy against microorganisms. The coating is useful to prevent bacterial colonization on a variety of surface including surfaces of medical devices.
Owner:海德罗默公司

Anti-microbial-adhesion fraction derived from vaccinium

A non-food anti-microbial-adhesion and aggregation composition comprising a suitable carrier and an effective amount of an adhesion inhibitory fraction isolated from juice from berries of the Vaccinium plant genus. In an embodiment the anti-aggregation and adhesion fraction is isolated from cranberry juice. It is characterized as being polymeric and having a molecular weight ≧14,000; an elemental analysis of carbon 43-51%, hydrogen 4-5%, no nitrogen, no sulfur and no chlorine; a nuclear magnetic resonance (NMR) line spectrum as set forth in FIGS. 2A and 2B; and an ultraviolet spectrum with an absorption peak at 280 nm in neutral or acidic pH solution which is absent in alkali solutions. This fraction exhibits adhesion inhibitory activity against P fimbriated bacteria, oral bacteria and Helicobacter pylori.
Owner:RAMOT AT TEL AVIV UNIV LTD

Acne-removing composition, acne-removing essence and preparation method of acne-removing essence

The invention discloses an acne-removing composition. The acne-removing composition is prepared from the following components in parts by weight: 0.25-2 parts of chitosan, 0.0005-0.002 part of polyquaternium-73, and 1-5 parts of aloe vera extract. The acne-removing composition selects the chitosan, the polyquaternium-73 and the aloe vera extract for reasonable blending, thus the synergetic acne-removing effect can be exerted, in the acne-removing composition, the polyquaternium-73 can kill and inhibit bacteria and propionigerms zitss, the aloe vera extract can exert the an repairing effect, meanwhile, the chitosan forms a protecting film on the surfaces of acnes, thus microbial adhesion and invasion can be prevented, wound healing can be promoted, repairing of the acnes is accelerated advantageously, and thus the acne-removing composition still has the quite high antibacterial, anti-inflammatory and acne removing effects even if only the a small amount of polyquaternium-73 is added. The invention further discloses an acne-removing skin care product, an acne-removing essence and a preparation method of the acne-removing essence.
Owner:GUANGZHOU RAINHOME PHARM&TECH CO LTD

Implantable or insertable medical device resistant to microbial growth and biofilm formation

InactiveUS7993390B2Prevent chemical modificationSurgeryPharmaceutical containersPolymeric surfaceActive agent
Disclosed are implantable or insertable medical devices that provide resistance to microbial growth on and in the environment of the device and resistance to microbial adhesion and biofilm formation on the device. In particular, the invention discloses implantable or insertable medical devices that comprise at least one biocompatible matrix polymer region, an antimicrobial agent for providing resistance to microbial growth and / or a microbial adhesion / biofilm synthesis inhibitor for inhibiting the attachment of microbes and the synthesis and accumulation of biofilm on the surface of the medical device. Also disclosed are methods of manufacturing such devices under conditions that substantially prevent preferential partitioning of any of said bioactive agents to a surface of the biocompatible matrix polymer and substantially prevent chemical modification of said bioactive agents.
Owner:BOSTON SCI SCIMED INC

Aluminum-based anti-corrosion, anti-microbial adhesion superhydrophobic film and preparation method thereof

The invention belongs to the technical field of metal surface treatment, and particularly relates to an aluminum-based anti-corrosion, anti-microbial adhesion superhydrophobic film and a preparation method thereof. An aluminum substrate obtained after polishing treatment is washed to be placed in a hydrothermal reaction kettle to be subjected to constant-temperature closing for making a hydrothermal reaction in the presence of an aqueous ammonia solution, and washing is carried out after the reaction is made; and then an ethanol solution containing perfluorodecyl triethoxysilane is used for conducting low surface energy molecule modification on the substrate, and the superhydrophobic film can be obtained. The superhydrophobic film and the preparation method have the advantages of being simple in process, low in cost and wide in application range, and the prepared aluminum-based superhydrophobic film has low surface adhesion, good self-cleaning property, good corrosion resistance and anti-microbial adhesion property.
Owner:INST OF OCEANOLOGY - CHINESE ACAD OF SCI

Immunogene adherence and method of making and using the same

The present invention discloses microbial adhesion inhibitors in the form of egg antibodies, and methods for their preparation and use. The inhibitors act by substantially preventing the adherence or attachment of the colony forming immunogen in the airways of host animals and humans. The suppressor is produced by inoculating female birds with the immunogen, harvesting the eggs containing antibodies against the immunogen, and separating the yolk and white from the eggshell. The yolk and egg white contents are administered to animals or humans by directly dispensing or entraining the contents in the air.
Owner:彼得·纳什 +1

Porous sewage purifying bamboo balls and processing method thereof

The invention relates to the technical field of sewage purifier processing, and in particular, relates to porous sewage purifying bamboo balls and a processing method thereof. The purified bamboo balls are porous balls with a diameter of 15-18 mm. The purified bamboo balls are prepared by mixing and processing bamboo powder particles, green steel shot and mixed cement in a ratio of (15-25):(2-5):(1-3); with use of the bamboo ball characteristics of good hydrophilicity and good microbial adhesion power, the bamboo balls are used as the main raw material and processed into the porous sewage purifying bamboo balls with the density of 1.1-1.3 g / cm<3> under the adhesion of mixed cement and green steel shot; the bamboo balls are inoculated with suitable microorganisms, the bamboo balls inoculated with the microorganisms are put into sewage to be treated, so as to purify the sewage by the microorganisms; air is blown into the sewage, so that the put bamboo balls can float up and down in the sewage, and the microorganisms adhering to the surface of the bamboo balls can fully play a role in purifying a water body. With up-and-down floating of the bamboo balls, the microorganism carriers areprevented from standing at the water bottom for a long time effectively, and the effect of microorganism purification of the sewage is prevented from being weakened.
Owner:张庆堂

Oral Care Compositions and Methods for Anti-Attachment Polymers and Coatings

Antimicrobial compositions and methods for depositing or coating the antimicrobial or antibacterial compositions on a substrate to prevent microbial adhesion are provided. The antimicrobial composition may include a cationic polymer having a poly-allylamine backbone. A portion of the poly-allylamine backbone may be functionalized with at least one of a guanidine functional group and a biguanide functional group.
Owner:COLGATE PALMOLIVE CO

Suspending filter material having trace element self-release function

The invention discloses a suspending filter material having a trace element self-release function. The suspending filter material comprises polyurethane sponge, and a trace element releaser is embedded in the polyurethane sponge. The filter material is suitable for a biochemical function of a suspending rapid filter, has good intercepting and adsorbing effect on suspending pollutants and has goodmicrobial adhesion, bio-film formation and bio-film protection effect, thereby being capable of better playing a role in quick filtering and biochemical treating; the trace element releaser can provide needed trace elements for microorganisms to grow, so that microbial adhesion and bio-film formation are better facilitated.
Owner:SHENZHEN GRADUATE SCHOOL TSINGHUA UNIV

Pervaporation membrane with specific function and preparation method and application thereof

The invention relates to a pervaporation membrane material with a specific function. The pervaporation membrane material is prepared by polymerizing light response type polysiloxane and a light response type diluting monomer in the presence of a photoinitiator. The pervaporation membrane material contains a light response type polysiloxane unit and a light response type diluting monomer unit, wherein the photoresponse type diluting monomer has a photoinitiation group and a fluoroalkyl chain at the same time, so that the prepared fluorine-containing pervaporation membrane has a better hydrophobic effect than an original PDMS membrane, and meanwhile, the fluorine-containing pervaporation membrane can reduce free energy on the surface of the membrane, so that the biological pollution resistance of the membrane is enhanced (microbial adhesion is reduced). The separation performance and the long-term stability of the membrane are improved due to extremely high hydrophobicity and pollution resistance.
Owner:BEIJING UNIV OF CHEM TECH

Application of non-release type antimicrobial adhesion coating in antibacterial pipe

The invention relates to application of a non-release type antimicrobial adhesion coating in an antibacterial pipe. The main component of the coating is composed of a copolymer of two monomers, namely bornyl acrylate (BA) and polyethylene glycol diacrylate (PEGDA), and the amphiphilic three-dimensional chemical antibacterial polymer coating is constructed; and the coating has good anti-microbial adhesion. A preparation method of the coating mainly comprises the following steps: 1, fixing a photoinitiator on the surface of a high polymer material; and 2, carrying out surface free radical-initiated polymerization on the monomers to realize grafting and copolymerization. The preparation method of the coating is simple, and the obtained grafted coating is safe and stable; respective advantages of the bornyl polyacrylate and the polyethylene glycol diacrylate can be fully exerted, and microbial adhesion can be synergistically prevented; and the coating can be applied to surface modification of most high polymer materials, and the structure flatness of the grafted coating can be ensured.
Owner:BEIJING UNIV OF CHEM TECH

Application of non-release type anti-microbial adhesion coating in antibacterial medical instrument

The invention relates to application of a non-release type anti-microbial adhesion coating in antibacterial medical instruments, the main component of the coating is composed of copolymers of two monomers of bornyl acrylate (BA) and polyethylene glycol diacrylate (PEGDA), an amphiphilic three-dimensional chemical antibacterial polymer coating is constructed, and the coating has good anti-microbial adhesion. The preparation method of the coating mainly comprises the following steps: 1, fixing a photoinitiator on the surface of a medical instruments; and 2, carrying out surface radical-initiated polymerization on a monomer to realize grafting and copolymerization. The preparation method of the coating is simple, and the obtained grafted coating is safe and stable; respective advantages of the bornyl polyacrylate and the polyethylene glycol diacrylate can be fully exerted, and microbial adhesion can be synergistically prevented; the coating can be applied to modification of the surface of a medical instrument, and the structure flatness of the grafting coating can be ensured.
Owner:长沙市盈尔丰新材料有限公司

Modifier for microbial adhesion rate and application thereof

The invention discloses a modifier for a microbial adhesion rate and application thereof, and relates to the technical field of biology. The modifier for the microbial adhesion rate is suitable for regulating the adhesion rate of microorganisms with the mucous membranes or the skin, and contains a surfactant, and the concentration of the surfactant is lower than the critical micelle concentration (CMC) of the surfactant. The modifier for the microbial adhesion rate can increase the probability and speed of the contact of the microorganisms and the mucosal cells or skin cells. Meanwhile, by the adoption of the surfactant, the cell-surface hydrophobicity of the microorganisms is changed, the microbial adhesion rate of the beneficial microorganisms with the mucosal epithelial cells or the skin cuticle is increased, the microorganisms are easily colonized on the mucous membranes or the skin, the microorganisms can continuously take effect for a long time, the modifier has broad application prospects.
Owner:CHENGDU JIYANGWU TECH CO LTD

Hydrophobic texturised foley catheter with low microbial adhesion

The invention relates to medical equipment for treatment, specifically medical equipment for extracting and draining fluids contained in the bladder of a patient. The Foley catheter according to the invention comprises tubing, with at least two lumens, made of a biocompatible polymer material with a length of between 100 and 400 mm and outer diameters of between 1 and 15 mm. The surface of the tubing has a high-relief texture with a maximum height of 30 micrometers and patterns designed to generate the property of hydrophobicity and to reduce the adhesion of bacteria to said surface. A collecting funnel with at least two channels, made from medical-grade polymer material, is fixed to the distal end of the tip of the tubing, while the tip of the tubing is closed in such a way that it forms a rounded tip. A flexible inflatable balloon is arranged upstream of the tip, for the anchoring of the catheter.
Owner:EQUIPOS MEDICOS VIZCARRA

A method for enhancing microbial attachment effect in chalcopyrite bioleaching process

The invention discloses a method for enhancing the microorganism adhesion effect in the bioleaching process of chalcopyrite, and belongs to the technical field of bioleaching. The method comprises the steps that stimulus intensity washing acclimatization is conducted on cells adherent to ore surfaces, different bioleaching systems such as a pure thelloobacillus ferrooxidans system and a pure thiobacillus thiooxidans system which are leached through the chalcopyrite are verified, and it is found that the method can efficiently enhance the microorganism adhesion effect in the bioleaching process; operation is easy, and the method is suitable for large-scale application and promotion.
Owner:JIANGNAN UNIV

Method for preparing pressure retarded osmosis membrane modified by zwitterionic random copolymer

The invention relates to a method for preparing a pressure retarded osmosis membrane modified by a zwitterionic random copolymer. The method comprises the steps that methyl-2-[methyl-(4-pyridine)dithiocarbonate]propionate is used as a chain transfer agent, azobisisobutyronitrile is used as an initiator, N-vinylimidazole and an N-vinylphthalimide monomer containing an amino protecting group are subjected to random copolymerization; a poly N-vinylimidazole chain segment is subjected to quaternization under the action of propane sultone and 4-bromobutyric acid separately; under the action of hydrazine hydrate, a poly(N-vinylphthalimide)chain segment is subjected to amino deprotection to obtain a zwitterionic polymer; and the zwitterionic polymer is prepared into an aqueous solution to be grafted and modified on a porous support layer of an osmosis composite membrane. A comonomer used in the method is simple and easy to obtain, the random copolymer is convenient to synthesize, the condition is mild, and realization is easy; the chemical stability and water solubility of a graft polymer are improved, and the cost is greatly reduced; and excellent anti-protein and microbial adhesion areachieved.
Owner:SHENZHEN RES INST OF WUHAN UNIVERISTY

Non-release type antimicrobial adhesion coating as well as preparation method and application thereof

The invention relates to a non-release type antimicrobial adhesion coating and a preparation method thereof. A polymer forming the coating is formed by copolymerization of two monomers, namely bornyl acrylate and polyethylene glycol diacrylate; and the coating has good antimicrobial adhesion. The preparation method of the coating mainly comprises the following steps: firstly, preparing a solution with a certain concentration from the monomers and a photoinitiator, and then carrying out two-step modification on a high polymer material by using a photo-grafting method, wherein in the first step, the is photoinitiator fixed on the surface of the high polymer material, and in the second step, surface free radical-initiated polymerization is conducted on the monomers to realize grafting. The preparation method of the coating is simple, and the obtained grafted coating is safe and stable; respective advantages of the bornyl polyacrylate and the polyethylene glycol diacrylate can be fully exerted, and microbial adhesion can be synergistically prevented; and the coating can be applied to surface modification of most high polymer materials, and the structural flatness of the grafted coating can be ensured.
Owner:BEIJING UNIV OF CHEM TECH

Composition and method for inhibiting microbial adhesion on surfaces

A composition includes a surfactant that is a linear alkylbenzene sulfonate, an acid thereof, or a combination thereof and that is present in an amount of from about 5 to about 30 weight percent actives based on a total weight of the composition and has the structure:wherein each m is independently a number of from 0 to 16, each n is independently a number of from 0 to 16, the sum of each m+n is a number of from 4 to 16, and X is a counter ion. The composition also includes a defoamer in an amount of from about 1 to about 20 weight percent actives based on a total weight of the composition, a thickening agent in an amount of from greater than zero to an amount of about 3 weight percent actives based on a total weight of the composition, and water.
Owner:SOLENIS TECH CAYMAN

Water-resistant long-acting inorganic zinc oxide super-hydrophilic coating as well as preparation method and application thereof

The invention belongs to the technical field of functional coatings, and particularly discloses a durable inorganic super-hydrophilic coating as well as a preparation method and application thereof. The durable inorganic super-hydrophilic coating is prepared from the following raw materials in percentage by mass: 30 to 60 percent of silicate, 5 to 25 percent of zinc oxide, 10 to 40 percent of water and 0.1 to 5 percent of a wetting agent. A coating layer formed by the durable inorganic super-hydrophilic coating prepared by the invention is a flat rigid coating layer, has good appearance, excellent antifouling self-cleaning and anti-microbial adhesion properties, and also has the characteristics of long-term underwater stability and high mechanical strength. The paint can be used for building outer walls, household inner walls and the like by utilizing the antifouling and self-cleaning characteristics of the paint, has excellent underwater oleophobic performance, and can be used in the fields of oil fields and oil-water separation.
Owner:GUANGZHOU UNIVERSITY
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