Catheters and a method of preparation thereof, the
catheter comprising a
catheter body, a juncture hub, extension lines and connectors, the
catheter body having a proximal end, a distal end, an exterior surface, a tip region having a length of 10 cm measured from the distal end of the catheter body, and at least two lumen, each of the catheter body lumen having a proximal end, a distal end, a Lumen
Aspect Ratio of at least 3:1, and an intraluminal surface, the distal ends of the at least two catheter body lumen being (i) non-coterminus or (ii)
laser-
cut, the exterior surface of the catheter body in the tip region or the intraluminal surface of the two catheter body lumen comprising a hydrophilic
polymer layer having an Average Dry Thickness of at least about 50 nanometers.