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Acne-removing composition, acne-removing essence and preparation method of acne-removing essence

A technology of essence and composition, applied in the field of essence and its preparation, and acne-removing composition, can solve the problems of high cost, complicated process, many components, etc., and achieve the effects of reducing dosage, simple preparation process and reducing cost

Inactive Publication Date: 2019-02-22
GUANGZHOU RAINHOME PHARM&TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Existing anti-acne products have many ingredients, complicated process and high cost

Method used

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  • Acne-removing composition, acne-removing essence and preparation method of acne-removing essence

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1～15

[0026] Examples 1-15 are examples of the acne-removing essence of the present invention, and the formulas of the acne-removing essence described in Examples 1-15 are shown in Table 1.

[0027] The preparation method of the anti-acne essence described in Examples 1-15 comprises the following steps:

[0028] (1), dissolving chitosan, sclerotin and propylene glycol with water;

[0029] (2), heating to 80°C, stirring speed is 15r / min, stirring for 20min;

[0030] (3), cooling down to 45°C, adding polyquaternium-73 dissolved in butanediol, the stirring speed is 20r / min, and the time is 5 minutes;

[0031] (4), add hexanediol and aloe extract, and stir at a speed of 30 r / min for 5 minutes to obtain the acne-removing essence.

Embodiment 16

[0037] In order to verify the antibacterial effect of the anti-acne essence of the present invention, the present invention is implemented with reference to GB15979-2002 "Hygienic Standards for Disposable Sanitary Products" Appendix C 4 "Bacteriostatic Performance Test Method for Dissolution Anti-bacteria (Inhibition) Products" Example 1~15 and comparative example 1~3 described acne essence are carried out bacteriostasis determination: (1) the preparation of bacterial suspension: get Propionibacterium acnes (ATCC6919) 24h culture and use 0.03mol / L phosphate buffer Washed down, made 10 4 ~10 6 CFU / mL bacterial suspension; (2) Take 1g of the sample to be tested, add 0.1mL of the above bacterial suspension to coat and mix evenly, start timing, add 9mL0.03mol / L phosphate buffer solution after 20min and mix well, do After appropriate dilution, take 3 of the dilutions, take 1mL respectively and put them in two parallel plates, then add the corresponding culture medium and incubate ...

Embodiment 17

[0045] Clinical trials are carried out on the anti-acne essence described in Examples 1-7 and Comparative Examples 1-3, specifically as follows:

[0046] Number of people: 120 people (65 men, 55 women), divided into 12 groups, 10 people in each group, with acne on the face

[0047] Time: 21 days

[0048] Part: face

[0049] Sample: the anti-acne essence described in Examples 1-7 and Comparative Examples 1-3

[0050] Evaluation: Conduct evaluation and take pictures according to GAGS scoring method (photo not shown):

[0051] The GAGS scoring method is the Global Acne Grading System (GAGS), a comprehensive acne grading system (GAGS) proposed by Doshi et al. in 1997. It is a scoring method with the characteristics of accuracy, strong consistency, rapidity and good overall evaluation effect. Specifically: According to the density, distribution and approximate area of ​​the pilosebaceous unit, the acne-prone areas are divided into 6 areas: Ⅰ area, forehead, Ⅱ area: right cheek, ...

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Abstract

The invention discloses an acne-removing composition. The acne-removing composition is prepared from the following components in parts by weight: 0.25-2 parts of chitosan, 0.0005-0.002 part of polyquaternium-73, and 1-5 parts of aloe vera extract. The acne-removing composition selects the chitosan, the polyquaternium-73 and the aloe vera extract for reasonable blending, thus the synergetic acne-removing effect can be exerted, in the acne-removing composition, the polyquaternium-73 can kill and inhibit bacteria and propionigerms zitss, the aloe vera extract can exert the an repairing effect, meanwhile, the chitosan forms a protecting film on the surfaces of acnes, thus microbial adhesion and invasion can be prevented, wound healing can be promoted, repairing of the acnes is accelerated advantageously, and thus the acne-removing composition still has the quite high antibacterial, anti-inflammatory and acne removing effects even if only the a small amount of polyquaternium-73 is added. The invention further discloses an acne-removing skin care product, an acne-removing essence and a preparation method of the acne-removing essence.

Description

technical field [0001] The invention relates to the technical field of cosmetics, in particular to an acne-removing composition, an essence and a preparation method thereof. Background technique [0002] Acne is a chronic skin disease that occurs in the pilosebaceous glands, and there are various factors. Among them, the causes of acne include internal and external factors. Internal factors: endocrine dysfunction, increased or relatively increased secretion of male hormones, stimulate hypertrophy and hyperplasia of sebaceous glands, and increased oil secretion; external factors: neuropsychiatric factors; dietary factors; personal behaviors such as stool and sleep Factors; tobacco, alcohol and other hobby factors, drug factors, cosmetics and skin care factors, etc. In addition, with the improvement of living standards, there are some raw, cold, spicy, greasy and fatty foods in the diet, as well as irregular work and rest time under the influence of high-pressure life, which ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9794A61K8/73A61K8/49A61Q19/00A61Q17/00A61P17/10A61P31/04A61P31/02
CPCA61K8/49A61K8/736A61K2800/592A61Q17/005A61Q19/00A61K8/9794A61P17/10A61P31/02A61P31/04
Inventor 车七石刘少辉
Owner GUANGZHOU RAINHOME PHARM&TECH CO LTD
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