124 results about "Biological Absorption" patented technology

The invention relates to compound millimicron fibrous membrane material of cellulose and cellulose matrix which can perform the biological degradation and the biological absorption and a preparation method thereof and an industry and medical purpose, and belongs to the biological macro-molecule non woven fabric material field which can perform the biological degradation and the biological absorption. Electrostatic spinning equipment is used to obtain the fibrous membrane material which can perform the biological degradation and the biological absorption, the weight of the cellulose is taken as basic reference, the component of the material comprises cellulose more than 0 and less than or equal to 100 weight parts, other biomacromolecule more than and equal to 0 and less than 100 weight parts, 0 to 10 weight parts of curative drug or 0 to 50 weight parts of inorganic catalyzer and / or 0 to 50 weight parts of inorganic strengthening agent. The material of the invention has good biological compatibility, biological degradation property and degradation absorptivity, and can be used for haemostasia material, wound cladding material, organization engineering supporting rack material, the transportation and release of medicine, artificial skin and blood vessel, and postoperation anti blocking material, beauty material and catalyzer carrier, filtering membrane and radiation protection material and so on.

A non-polymeric or biological coating applied to radially expandable interventional medical devices provides uniform drug distribution and permeation of the coating and any therapeutic agents mixed therewith into a targeted treatment area within the body. The coating is sterile, and is capable of being carried by a sterile medical device to a targeted tissue location within the body following radial expansion. The therapeutic coating transfers off the medical device due in part to a biological attraction with the tissue and in part to a physical transference from the medical device to the targeted tissue location in contact with the medical device. Thus, atraumatic local tissue transference delivery is achieved for uniform therapeutic agent distribution and controlled bio-absorption into the tissue after placement within a patient's body with a non-inflammatory coating.

The invention discloses small molecule polypeptide Ca-chelate of fishbone, which belongs to the field of functional food or additive. The method for preparing the small molecule polypeptide Ca-chelate of the fishbone comprises the following steps: boiling the fishbone at high temperature and high pressure; pulping to obtain the fishbone paste; utilizing the compound protease to execute enzymolysis; centrifuging to obtain the liquid supernatant and the sediment; filtering the liquid supernatant to obtain the small molecule polypeptide liquid of the fishbone; executing the composite acid acidification through citric acid and lactic acid for the sediment so as to obtain the fishbone calcium liquid; mixing the small molecule polypeptide liquid of the fishbone with the fishbone calcium liquid; executing the chelation at 40-50 degrees centigrade while the pH value is 7.5-8.5; and drying to obtain the small molecule polypeptide Ca-chelate of the fishbone. The invention has high Ca-chelate rate which reaches over 90%, and has high biological absorption rate of the calcium which reaches over 70%. The invention has no side effects, has good flavor, can be directly absorbed from intestinal mucosa after being eaten, solves the problems that the solubility of the traditional calcium source is bad, the absorption rate is low and the side effect is large, and solves the problem of producing calculi. In addition, the invention has a simple preparation method and low cost.

Treatments and devices for generating and using interleukin-1 receptor antagonist (IL-1ra). An implantable device is loaded with adipose tissue and / or white blood cells and inserted into an inflammation site in a patient to produce interleukin-1 receptor antagonist in vivo. The implantable device has an enclosed or substantially enclosed body that defines an internal space. At least a portion of the body comprises a first bioresorbable material and a second bioresorbable material is within the internal space along with one or more voids. The second bioresorbable material includes an activation surface to activate adipose tissue and / or white blood cells loaded into the device to produce IL-1ra.

The invention relates to fish scale protein peptide calcium chelate, a microcapsule calcium supplement of the chelate and preparation methods thereof. In the invention, calcium chloride and the enzymatic hydrolysate of fish scale protein are chelated, thus improving the solubility of the calcium salt under a subalkaline condition in the intestinal tracts and improving the absorption utilization ratio of calcium, and the preparation process is safe and pollution-free. In the invention, an appropriate wall material is also adopted for microencapsulating the fish scale protein peptide calcium chelate to prepare the microcapsule calcium supplement of the fish scale protein peptide calcium chelate; the calcium supplement can cover up the off flavor of the calcium salt and can gradually release Ca<2+> under the subalkaline condition in the intestinal tracts, and the biological absorption utilization ratio of the Ca<2+> is high without toxic side effect; and due to the fish scale protein peptide, the fish scale protein peptide calcium chelate not only can prevent and treat osteoporosis, but also has the physiological functions of resisting oxidation, adjusting immunity, reducing blood pressure and the like.

The present invention relates to the use of multiple different light emitting molecules that emit different and detectable emission signals to provide systems and methods to detect different target products in a single assay sample, wherein the different light emitting molecules are positioned an optimal distance from metallic particles thereby enhancing emissions. Preferably, the systems and methods further comprise use of either microwave or sonic energy to increase binding reactions, timing of such reactions within the assay sample and reduce background non-specific biological absorption.

The present invention relates to a sewage treatment combined wet land system and its sewage treatment process. Said sewage treatment combined wet land system includes biological regulation pool, aerobic degradation and microbial culture pool, artificial underflow wet land unit and artificial surface flow wet land unit, and its sewage treatment process includes the measures of natural precipitation, biological absorption, degradation and conversion, aeration reaction and others so as to make the sewage obtain purification treatment.

The invention belongs to the surface modification polymer superfine fiber film field, in particular to a polyester superfine fiber film material with surface graft modification, biological degradation and biological absorption, a chemical surface modification method thereof, a device for preparing the film and an application of the film in biomedicine. In the invention, non-woven fabric materials composed by fibers with the diameter of between tens of nanometers to thousands of nanometers are prepared by utilizing an electrostatic spinning process, and the non-woven fabric materials are combined with substrate materials by the polymerization of functional polymers on material surfaces in a covalent bond mode, and a plurality of functional groups are introduced on surfaces of superfine fiber film materials, which improves the hydrophilic performance and the hydrophobic performance of material surfaces and improves the biocompatibility of materials with tissue cells. The materials prepared by the invention can be applied to the production of surgical suture materials, fixing materials for plastic surgery, drug-controlled release materials and other macromolecule implants materials; and the surface modification method of the invention can be applied to the surface modification of micro channels of microfluidic devices and can better keep features of channels.

The present invention provides a method for fabricating an implant stent with therapeutic effects. The method of the present invention includes designing and delineating a pattern of the implant stent, drilling a thin metal sheet to form positioning holes, cutting a desired pattern on the thin metal sheet according to the designed pattern, drilling a hole on a line rib of the stent to form a braided structure by a micro discharge processor according to the desired pattern. Then, the stent is cleaned and polished by the electropolish to trim the edge and the rough surface of the stent. Then, the biodegradable material, PLLA, PGA, fibrinogen, the polyurethane-polyethylene oxide mixed with the heparin or the combination thereof, is used for forming the mixed material with the high molecular weight, and is solved in a solvent, wherein another grinded therapeutic drug with the micro or the nano size is added. The drug can be As2O5, an anti-caner drug, or an anti-inflammation drug. The solution with the bioadsordable material having a therapeutic drug is atomized and sprayed on the outer and inner surfaces of the stent. Since a row of holes are arranged on the line rib of the stent, each hole is immersed into the solution due to the capillary phenomenon. When the solution is completely evaporated, the biodegradable and absordable material and the drug are coagulated to form a solid and to strongly coat on the surface of the stent. When the stent is implanted into a human body, the solid layer is slowly degraded and released on the injured site, so that the vessel is prevented from restenosis, and the therapeutic effect is achieved. The stent can be fabricated by the precision machine technology in Taiwan, so that the implant stent with low cost and therapeutic effects is obtained.

An osmotic solid pharmaceutical formulation for the controlled diffusional and osmotic delivery of a therapeutic agent to an environment of use comprising: a core comprising a physical mixture of a sulfoalkyl ether cyclodextrin, a therapeutic agent and a pharmaceutically acceptable carrier; and a membrane surrounding said core and comprising a film forming agent and a pore forming agent, said membrane having a passageway therethrough for communicating said core to an environment of use; wherein, a first portion of said therapeutic agent diffuses through said membrane and a second portion of said therapeutic agent passes through said passageway; and a major portion of said therapeutic agent is not complexed with said sulfoalkyl ether cyclodextrin.

The invention relates to a fiber compact double-layered composite film, which consists of two layers including a smooth compact film and a nano fiber film. The two films are combined tightly and cannot be separated. A preparation method of the fiber compact double-layered composite film includes mixing and dissolving polylactic-co-glycolic acid and polylactide-b-polyethylene glycol into N, N-dimethylformamide or acetone or mixture of the N, N- dimethylformamide and the acetone so as to obtain uniform polymer solution; then knifing the polymer solution on a roller or realizing electrostatic spinning on the roller and then drying the roller after heating the roller so as to obtain the compact film layer; and finally realizing electrostatic spinning on the compact film to obtain a fiber film layer, and accordingly obtaining the fiber compact double-layered composite film. The fiber compact double-layered composite film has excellent biocompatibility, biodegradation and biological absorption, and simultaneously has the advantages of light weight and softness. Besides, mechanical property and degradation period of the fiber compact double-layered composite film can be flexibly adjusted according to service needs.

The present invention relates to the use of multiple different light emitting molecules that emit different and detectable emission signals to provide systems and methods to detect different target products in a single assay sample, wherein the different light emitting molecules are positioned an optimal distance from metallic particles thereby enhancing emissions. Preferably, the systems and methods further comprise use of either microwave or sonic energy to increase binding reactions, timing of such reactions within the assay sample and reduce background non-specific biological absorption.

The invention discloses a method for preparing magnetic chitosan nano particles and processing heavy metal wastewater, belonging to the technical field of material preparation. The method disclosed by the invention comprises the following steps: firstly, weighing ferrous salt and ferric salt as raw materials for preparing a magnetic material, wherein the raw materials are dispersed in a chitosan acetic acid solution after being dissolved; and dropping the mixed liquor into alkali liquor through an injector to obtain the magnetic chitosan particles, wherein the prepared magnetic chitosan particles are provided with a chitosan-nano ferroferric oxide core shell structure and a nano biological absorption material with excellent absorption performance. The method disclosed by the invention is simple and easy to operate. The nano biological absorption material prepared by the method disclosed by the invention is used for processing the heavy metal wastewater.

The invention discloses a method of generating hydrogen for twice at the same time that the waste water containing cadmium heavy metal is treated by harmless biological absorption by using an algae and fungi synergistic system, and belongs to the technical field of the environmental energy source. The method is mainly characterized in that algae cell wall and fungi cell wall are cooperated to absorb the cadmium; at the same time of removing the cadmium, Chlamydomonas Reinhardtii can generate hydrogen by using the characteristic that the stress effect of the heavy metal of the Chlamydomonas Reinhardtii is similar to the deficiency effect of sulfur element during cultivation; furthermore, butyric acid clostridium is used to ferment the biomass cumulated by the photosynthesis of the Chlamydomonas Reinhardtii to re-generate hydrogen; the fungi used during cadmium absorption and hydrogen generation is treated in an immobilized way. The method has high efficiency, is easy for downstream treatment, can get clean water and a great deal of hydrogen finally with qualified cadmium concentration, and can be widely used for the clean treatment and energy recovery utilization to industrial waste water containing the cadmium.

The invention provides a water quality information computing device and a water quality information computing method, which are used for simulating and computing a concentration of pollutants in a water pollution accident, wherein the water quality information computing device comprises an information input module, a computing module and a displaying module, wherein the information input module is used for inputting information for reflecting the concentration of pollutants in an upper reach, the computing module is used for computing the concentration of pollutants of polluted water quality of a lower reach by using a one-dimensional water quality simulating system dynamics model according to input information of the information input module, and the displaying module is used for displaying the information input by the information input module and a computing result output by the computing module. According to the water quality information computing device disclosed by the invention, the system dynamics is applied to a dynamic simulation research of water quality variation of water pollution accidents. The one-dimensional water quality simulating system dynamics model is established to carry out dynamic analogue simulation on the concentration variation of the pollutants in rivers due to physical, chemical and biological processes caused by convection, diffusion, attenuations caused by chemical reactions and biological absorption and the like, so that the concentration of the pollutants in a downstream section is forecasted.

The invention discloses a special marine dietary food for patients with liver deficiency. The dietary food is prepared from the food-borne marine oligopeptides as the main raw materials, and marine bioactive polysaccharide, seaweed powder, nutritional amino acids, oligosaccharides, nutrients, vitamins and minerals by mixing. The special marine dietary food can be made into powder or particles anddissolved by warm water for use. The special marine dietary food can be easily dissolved, and has the greatest biological absorption and maximum bioavailability for human body. The special marine dietary food can provide body with marine protein with high-quality, activity factors and nutrients, and supplement essential vitamins and minerals for human body, and can be helpful to improve the nutritional condition of patients with liver deficiency. Through the coordination of the food-borne marine oligopeptides, the biological active ingredients in the marine bioactive polysaccharides in, the seaweed powder, the nutritional amino acids and other factors together, the special marine dietary food can protect human livers, and improve the immunity to prevent the occurrence of liver disease. The food is suitable for the patients with liver deficiency.

The invention provides an active peptide embedded nanoparticle and a preparation method thereof and aims to solve the problem that albumen derived active peptides which are easily degradable in a gastrointestinal digestive system cannot be completely absorbed currently. By adoption of ionic gel, chitosan and sodium tripolyphosphate serve as nano coating materials to realize embedding of albumen derived active peptides, with four different molecular weights, obtained by enzymolysis, and consequently the albumen peptide-chitosan nanoparticle great in embedding performance is obtained. A gap in protection and promotion of biological absorption and utilization of the albumen derived active peptides is filled, a new idea is provided for deep processing in the industry of egg products, and resource integration and maximal reasonable application of the egg products are realized.

The invention discloses a compound magnetic biological adsorbent, which is characterized in that dry mycelia of white rot fungi are used as a carrier, the mycelia are wound to a ball, Fe3O4 nano particles and calcium alginate are embedded into the ball, and the calcium alginate serving as immobilized medium is tightly connected together with the Fe3O4 nano particles. The preparation method for the adsorbent includes the steps: inoculating spore suspension of the white rot fungi into aseptic mixed liquid of the Fe3O4 particles and the calcium alginate under the aseptic condition, mixing uniformly, dropwise adding the mixed liquid of one volume into aseptic CaC12 solution of 4-10 volumes, standing at the room temperature to obtain reaction liquid including Fe3O4-calcium alginate-white-rot fungus microspheres, and performing immobilized culture so as to obtain the compound magnetic biological adsorbent after culture is completed. The compound magnetic biological adsorbent has the advantages of high adsorption capacity, high adsorption speed, high reuse rate, cleanliness, no pollution and the like.

The invention provides a water quality information calculating device and a water quality information calculating method, which are used for simulated calculation of the concentration of pollutants in water pollution accidents. The water quality information calculating device comprises an information input module, a calculating module and a display module, wherein the information input module is used for inputting information reflecting the concentration of pollutants on the cross section of an upstream river; the calculating module is used for calculating the concentration of pollutants polluting the water quality of the cross section of a downstream river by means of a two-dimensional water quality simulation system dynamics model according to the input information of the information input module; and the display module is used for displaying the information inputted by the information input module and calculated results outputted by the calculating module. The water quality information calculating device has the advantages that system dynamics is applied to dynamic simulation research on water quality variation of the water pollution accidents, the two-dimensional water quality simulation system dynamics model is established, dynamic analogue simulation is performed for concentration variation of the pollutants in the rivers caused by convection, diffusion, physical, chemical and biological processes such as attenuation and the like resulting from chemical reaction and biological absorption, and then the concentration of the pollutants on the downstream cross section can be predicated.

The invention provides an integrated treatment method and apparatus of odor and peculiar-smell gas. The integrated treatment apparatus comprises a suspended biological absorption area, a biological filtering adsorption area and a composite active carbon adsorption area; the suspended biological absorption area receives odor and peculiar-smell gas, the odor and peculiar-smell gas enters an aerationmain pipe and an aeration branch pipe to be uniformly aerated, ammonia pollutants and sulfides in the odor and peculiar-smell gas are degraded by a mixed solution of ammonia oxidizing bacteria and nitrous acid oxidizing bacteria microorganisms; the odor and peculiar-smell gas is suspended and absorbed by virtue of a strengthened washing pump; in the biological filtering adsorption area, the substances such as hydrogen sulfide in the odor and peculiar-smell gas are degraded by virtue of heterotrophic bacteria and fungi inoculated on composite biological filler; and the composite active carbonadsorption area comprises a granular active carbon adsorption area and a honeycomb active carbon adsorption area. By adopting the integrated treatment apparatus, the odor gas is continuously treated in multiple levels in a single device to reduce the loss of air pressure and the energy consumption of the device, so that the floor occupation area of the device is saved, and the operation and maintenance expense can be reduced.

The invention discloses a graphene oxide grafted modified oxidized regenerated cellulose hemostatic material and a preparation method thereof, relating to a hemostatic material and a preparation method thereof. The graphene oxide grafted modified oxidized regenerated cellulose hemostatic material aims to solve the problems that a modified material of the existing oxidized regenerated cellulose is poor in mechanical strength and biological absorption of the material and small in improvement degree of hemostatic performance. The graphene oxide grafted modified oxidized regenerated cellulose hemostatic material is prepared from graphene oxide containing amino groups on the surface and oxidized regenerated cellulose. The preparation method comprises the following steps: I, preparing graphene oxide subjected to acylating chlorination; II, preparing graphene oxide containing the amino groups; and III, performing chemical grafting to obtain the graphene oxide grafted modified oxidized regenerated cellulose hemostatic material. The graphene oxide grafted modified oxidized regenerated cellulose hemostatic material disclosed by the invention can be used for reducing the bleeding-stopping time by 7-17% when the material is used for stopping bleeding. The graphene oxide grafted modified oxidized regenerated cellulose hemostatic material and the preparation method thereof can be obtained according to the invention.

The active carbon producing process with tilapid bone includes the first enzyme processing, cleaning, stoving and crushing to obtain fish bone powder; the subsequent acid processing and activating process of the fish bone powder; and final stoving to obtain product. The said process changes the waste into high value matter and produces high absorption calcium CMC via extracting with mixed citric acid and malic acid. The bioavailability test shows that the active calcium has biological absorption rate as high as 60 %. In addition, the technological process is simple, low in production cost and stable in product quality.

The invention discloses a fiber tube reinforced hollow fiber composite biofilm as well as a preparation method and application thereof. According to the invention, a coating-immersion precipitation phase transformation method is adopted for utilizing a composite film spinning device to coat a braided tube by a casting solution liquid to prepare the fiber tube reinforced hollow fiber composite biofilm with high strength and high flux. The product provided by the invention has a large specific surface area, in particular, the specific surface area of the oxygen permeable film can be as high as 5108 m<2> / m<3>; the film is used as a carrier, a sufficient adhesion area can be provided for growth of microorganisms in a smaller space, so that a concentration of the microorganisms in the unit space is greatly improved, the treatment capacity per unit volume can be improved, and the aeration efficiency is high; the film has the characteristics of selective ventilation, and the oxygen absorptioncapacity is multiple times that of conventional equipment; and the product has the high-efficiency oxygen separation characteristic, so that the microorganisms are attached to the surface of the biofilm to form a biotic community to naturally form a stable ecosystem, the efficiency of biological absorption of water pollutants is accelerated, and the black odor problem can be thoroughly solved.

The invention belongs to the technical field of biological treatment of waste gas and relates to a spherical non-woven fabric filling started tower type anaerobic ammonia oxidation reactor. Filling is of an orange-segment-shape-like structure formed by uniformly arraying a framework, formed by modifying an original polyhedron hollow sphere, and a non-woven fabric. The filling is stacked in an absorption tower and is used for carrying out film formation through spraying anaerobic ammonia oxidation bacterium liquid; artificially synthesized ammonia-nitrogen wastewater is sprayed at the upper part; nitric oxide enters from the lower part of the reactor and is in countercurrent contact with liquid to be removed. The spherical non-woven fabric filling started tower type anaerobic ammonia oxidation reactor has the effects and benefits that a liquid film is easily formed by the spherical filling and absorption of gas is facilitated; the non-woven fabric on the filling has a large specific surface area and a coarse surface; the adhesion, growth and reproduction of anaerobic ammonia oxidation bacteria are facilitated; the removing efficiency of the nitric oxide is easy to improve; compared with traditional biological denitration, the reactor is environmentally friendly and has low operation cost; a sustainable treatment technology combining flue gas denitration and sewage denitrification is provided and has relatively good potential application prospect.

The invention discloses an aflatoxin B1 control compound biological agent and application thereof. The aflatoxin B1 control compound biological agent is formed by compounding bacillus subtilis, bacillus licheniformis, enterococcus faecium and yeast cell wall, wherein the bacillus subtilis, the bacillus licheniformis and the enterococcus faecium can effectively inhibit growth of mould in feeds. Theaflatoxin B1 control compound biological agent effectively combines two feed-contained aflatoxin B1 detoxification methods, namely, biodegradation and bio-absorption; the contained bacillus subtiliscan effectively degrade aflatoxin B1, and the contained yeast cell wall can effectively absorb aflatoxin B1. Besides, the aflatoxin B1 control compound biological agent can not only achieve mould preventing and cleaning functions, but also achieve microbial healthcare effects.

The invention relates to a partially covered stent used for treating bifurcation lesion coronary perforation and provided with a biological absorption film. The partially covered stent comprises a stent body composed of a tubular inner layer stent and a tubular outer layer stent, wherein the tubular inner layer stent and the tubular outer layer have identical length concentric line engraved nettedstructures, a tubular covering film is clamped between the inner layer stent and the outer layer stent, and the partially covered stent is characterized in that one end of the covering film is flushwith the stent body, and the length of the covering film accounts for 30-50% that of the stent body; the covering film is the biological absorption film; the biological absorption film is a poly-DL-lactic acid film. The partially covered stent has the advantages of being capable of covering a blood vessel perforation part to form a complete blood flow channel, effectively preventing closing and plugging of side branches, meanwhile easily realizing endothelialization in a stent body, and effectively reducing forming of thrombi.

There is provided an elastin molded article having flexibility, a biological absorption property and tear strength which is practically suturable by using a fiber structure comprising aliphatic polyester fibers having an average fiber diameter of 0.05 to 50 μm as a supporting base material. The elastin molded article is useful as a raw material for a tube or artificial blood vessel to be implanted in a body that has a biological absorption property and has tear strength and flexibility which allow the tube or artificial blood vessel to endure suture at the time of operation or the like.

The invention discloses a nanogold / lysine / oxidized regenerated cellulose composite hemostatic material and a preparation method thereof, relates to a hemostatic material and a preparation method thereof, and aims at solving the problems of obstruction to the biological absorption of a hemostatic material and slight improvement of the hemostatic performance due to a fact that the skin of a mammal is irritant to other body cells at a contact position and a large whitish granulation lump is formed at a use position in the use process of an existing oxidized regenerated cellulose modified material serving as the hemostatic material. The nanogold / lysine / oxidized regenerated cellulose composite hemostatic material is prepared from the nanogold and the oxidized regenerated cellulose on the surface of which the lysine is grafted; the preparation method of the hemostatic material comprises the steps of firstly, chemically grafting the lysine to the oxidized regenerated cellulose, secondly, preparing the aqueous dispersion of the nanogold, and 3, carrying out self-assembling of the nanogold, thereby obtaining the nanogold / lysine / oxidized regenerated cellulose composite hemostatic material. The invention successfully provides the nanogold / lysine / oxidized regenerated cellulose composite hemostatic material and the preparation method thereof.