23 results about "Biological Absorption" patented technology

A combined magnetic and bioabsorbable device for ventral hernia closure and / or tension distribution for maintenance of tissue apposition for healing, while avoiding a long-term footprint of foreign material and precluding materials spanning the interior layer of the abdominal closure where risk to visceral structures exists.

Embodiments described herein relate to a support device configured to provide tissue support, during implant-based breast surgery. Embodiments described herein include a matrix sheet disposed in a foldable sheet including one or more templates including at least one of a partial support template and a full support template. The partial support template is configured for use in shaping the matrix sheet into a support device for partial coverage for a breast prosthesis. The full support template is configured for use in shaping the matrix sheet into a support device for full coverage for a breast prosthesis. In some embodiments, the support device is a bioabsorbable mesh substrate, a bioabsorbable polymer coating, and one or more active pharmaceutical agents for delivery at the surgical site. The support device may be provided in various shapes for coverage of the breast prosthesis or provided with templates for various coverage of the breast prosthesis. The support device forms a macroporous scaffold, and the macroporous scaffold may act as a lattice for new tissue ingrowth.

Embodiments described herein relate to a support device configured to provide tissue support, during implant-based breast surgery. Embodiments described herein include a matrix sheet (1002) disposed in a foldable sheet (1104) including one or more templates including at least one of a partial support template (1110a, 1110b) and a full support template (1120). The partial support template is configured for use in shaping the matrix sheet into a support device for partial coverage for a breast prosthesis. The full support template is configured for use in shaping the matrix sheet into a support device for full coverage for a breast prosthesis. In some embodiments, the support device is a bioabsorbable mesh substrate, a bioabsorbable polymer coating, and one or more active pharmaceutical agents for delivery at the surgical site. The support device may be provided in various shapes for coverage of the breast prosthesis or provided with templates for various coverage of the breast prosthesis. The support device forms a macroporous scaffold, and the macroporous scaffold may act as a lattice for new tissue ingrowth.

A method and a system for performing a medical procedure including a scaffold for implanting in a hollow structure of a mammalian patient. The system includes a delivery device configured to deliver the scaffold to an implant location within the hollow structure. The scaffold, or one or more portions of scaffold, can be configured to bioabsorb, biodegrade, and / or otherwise decompose after implantation in a patient. The bioabsorption can occur over a period of time, such as a predetermined time period.

A hole closing material achieves less invasive treatment for atrial septal defect with no or little possibility of problems in the late post-treatment period. The hole closing material includes two tubular bodies (first tubular portion and second tubular portion) having a mesh structure formed of a bioabsorbable linear material, and includes: a proximal connecting part connected to a first end; and a distal connecting part connected to a second end and screwed to a delivery cable. The proximal connecting part and the distal connecting part are capable of selectively achieving: “locked” in which the proximal connecting part and the distal connecting part remain united; and “unlocked” in which the proximal connecting part and the distal connecting part do not remain united. The delivery cable passes through the substantially middle portion, is inserted into a hollow tube of the proximal connecting part, and passes out of the hole closing material in a direction from the second end to the first end.

Disclosed herein are compositions comprising a polymer and a metabolic inhibitor, as well as a method of using the composition to modulate an immune response. The composition may be produced in the form of a synthetic tissue for provision in a subject. The composition or synthetic tissue may further comprise additional therapeutic agents.

The present invention relates to the field of animal feed technology, and in particular to a pet food that is easily digestible and absorbable and a preparation process thereof. The preparation process comprises the following steps: preparing a chitin nanofiber suspension; preparing a modified pig liver protein solution; preparing a digestive aid additive; and preparing a pet food that is easily digestible and absorbable. The present invention improves the solubility of pig liver protein in water and makes it easier to disperse by grafting maleic anhydride onto pig liver protein. Pig liver protein is rich in high-quality protein. For pets, excessive high-quality protein is not easy to absorb, but will result in overnutrition. After pig liver protein is grafted with maleic anhydride, the surface properties of the protein are changed, which can better improve the absorption rate of organisms. In addition, the introduction of maleic anhydride can reduce the protein content in the modified pig liver protein solution, so that the protein content in the prepared pet food is within the range that the pet can absorb, and the prepared pet food is easy to digest and absorb.

The present disclosure provides bioabsorbable particles with a nucleic acid. The bioabsorbable particles also include a bioabsorbable polymer matrix and a lipid salt. both of which can be altered to affect the particle properties. The bioabsorbable particles may be administered to a patient for the treatment of diseases. Methods for making and using the bioabsorbable particles are also provided.

This invention relates to the field of deep-sea mining hose cleaning technology, specifically to an intelligent robot and method for cleaning adsorbed organisms on deep-sea mining hoses. The robot includes two shells, with a power storage compartment inside each shell for storing power. It also includes a visual drug application device for monitoring bioadsorption on the mining hose and performing preliminary drug treatment, a vortex-flow erosion device for further treatment of adsorbed organisms, a positioning and detection device for monitoring the treated mining hose, treating stubborn residual adsorbents, and monitoring the overall condition of the mining hose, an AUV thruster, and a communication control device. The communication control device includes an ACN underwater acoustic communication module and an intelligent processing module. The invention also includes a cleaning method using this robot. This application features multi-level collaborative cleaning, significantly improving the efficiency of bioadhesion removal, intelligent closed-loop control, and fully autonomous operation, reducing labor costs.

The invention provides an immobilized algal-bacterial symbiotic system and application thereof in harmless treatment of spiramycin production wastewater, and belongs to the technical field of environmental microorganisms. The algal-bacterial symbiotic system comprises bacillus subtilis with the preservation number of CGMCC (China General Microbiological Culture Collection Center) No. 15560 and microcystis aeruginosa FACHB-315. The immobilized microorganism product prepared from the algal-bacterial symbiotic system and the biological adsorption carrier ball has the following advantages: (1) the floatability of microalgae cells and the negative effects caused by discharge of free cells into natural water can be overcome; (2) the SPI removal rate can reach 98.49%, and the SPI removal capacity is high. Therefore, the method can effectively reduce ecological hazards and the like caused by the SPI entering the environment.

The application discloses a water body nitrogen biological removal capacity evaluation method based on macrobenthos functional traits, and comprises the following steps: S1, constructing a water body nitrogen biological removal capacity evaluation table based on macrobenthos functional trait evaluation final score; S2, collecting macrobenthos in the water body to be measured, and obtaining the final score of the macrobenthos functional trait evaluation based on the trait grade of the macrobenthos which is strongly related to the water body nitrogen biological removal rate, and then obtaining the corresponding classification based on the water body nitrogen biological removal capacity evaluation table. The application does not need to perform complex tracer adding, real-time water quality monitoring and cumbersome calculation process, only needs to collect and identify the macrobenthos in the stream, obtains the macrobenthos functional trait evaluation result, and then obtains the nitrogen biological absorption rate of the water body to be measured by means of the pre-constructed evaluation table. The application greatly reduces the workload, makes the whole evaluation process more simple and fast, and improves the evaluation efficiency.

Provided is a non-tubular brain damage recovery material which is used to cover and / or fill a damaged part of the brain, the brain damage recovery material including: (A) a cross-linked body with which a bioabsorbable polysaccharide having a carboxyl group in a low endotoxin molecule is covalently bonded and cross-linked with at least one crosslinking reagent selected from among a compound represented by general formula (I) and salts thereof; and (B) a bioabsorbable polymer. R1HN—(CH2)n—NHR2 (I) [in the formula, R1 and R2 each independently represent a hydrogen atom or a group represented by formula of —COCH(NH2)—CH2]4—NH2, and n represents an integer from 2 to 18]. Accordingly, provided is a medical material which can recover a damaged part of the brain.

In various embodiments, a tissue thickness compensator can comprise a compressible extracellular matrix and a bioabsorbable material dispersed within the extracellular matrix, wherein the bioapsorption of the bioabsorbable material is configured to leave behind channels in the extracellular matrix. The tissue thickness compensator can also comprise generation means for generating the ingrowth of tissue into the channels. In at least one embodiment, the tissue thickness compensator can comprise dissolvable wicking members which, when dissolved, can leave behind channels in the tissue thickness compensator. In certain embodiments, the tissue thickness compensator can comprise at least one rupturable capsule.

The present invention discloses a genetically engineered bacterium construction and application for synthesizing curcumin glucoside, belonging to the field of genetic engineering. The present invention uses Escherichia coli BL21 (DE3) as an engineering strain, overexpresses two key enzymes involved in UDP-glucose synthesis in Escherichia coli, namely glucose-6-phosphomutase and UDP-glucose pyrophosphorylase, to increase the level of endogenous UDP-glucose in the cell, effectively improving the synthesis efficiency of whole-cell catalytic synthesis of curcumin glucoside; at the same time, overexpresses the UDP-glucosyltransferase CaUGT2 from Catharanthus roseus; the genetically engineered bacterium can efficiently synthesize curcumin monoglucoside and curcumin diglucoside, can effectively solve the solubility problem of curcumin, improve the biological absorption rate and biological availability of curcumin, and expand its application value in medicines, cosmetics and food.

A system and method for vasculature closure from a single access point are provided, utilizing specifically designed bioresorbable devices. The bioresorbable devices may include a disk-shaped substrate layer with an opening extending from a first surface to a second surface, configured to allow a guidewire to pass through, and a coating configured to encourage adhesion to an interior vessel wall. The system utilizes a guidewire having an expandable portion passing through the opening. The bioresorbable device is carried into the blood vessel within a first tubular member in a compressed configuration, and then ejected from the first tubular member by a second tubular member. The bioresorbable member then assumes a partially expand configuration. The expandable portion of the guidewire can then be used to press the bioresorbable device against an interior vessel wall, allowing it to adhere, after which the expandable portion can be deflated.

A biocompatible antimicrobial composition effective against microbial biofilms, including in vivo biofilms containing gram-positive bacteria, can be delivered to and used near the spinal column of vertebrates. Once introduced to an area colonized with a bacterial biofilm, particularly an intervertebral disc, the antimicrobial composition weakens the EPS / ECPS macromolecules of the biofilm, which makes the entire biofilm structure susceptible to being dislodged from the affected area or biosorbed. Additionally or alternatively, certain of the subcomponents of the solute component, as well as perhaps the organic liquid(s) of the solvent component, might lyse microbes, particularly gram-positive bacteria, previously protected by the EPS / ECPS macromolecules. Swelling of and around previously impacted intervertebral discs can be reduced or eliminated, often resulting in appreciable reductions in patient pain levels.

The present disclosure provides bioabsorbable particles that include nucleic acids. The bioabsorbable particles also include a bioabsorbable polymer matrix and a lipid salt, both of which can be modified to affect the properties of the particle. The bioabsorbable particles can be administered to a patient for the treatment of a disease. Methods of making and using the bioabsorbable particles are also provided.

The present invention discloses a method for regulating and recovering a sewage treatment system after a shock. The method comprises: when the fluctuation amplitude of the respiratory rate is less than 10% of the lower limit of the normal range for more than 60 minutes, an alarm is notified to the control system, water intake is stopped, and powdered activated carbon and a biosorbent are added to the system. The alarm is released when the respiratory rate returns to the normal range, and the addition of activated carbon is first stopped. When the effluent ammonia nitrogen concentration is lower than the emission standard limit, the addition of the biosorbent is stopped and water intake is restarted to continue operation. The system achieves rapid recovery after the shock and enters a stable operating state. The biosorbent is based on cross-linked chitosan embedded with calcium carbonate, on which heterotrophic bacteria are adsorbed and grown, wherein the heterotrophic bacteria account for 5% to 50% of the mass of the adsorbent. The method of the present invention can achieve early warning and timely eliminate the risk of shock. It does not require re-acclimation and cultivation of sludge, reduces recovery time, and ensures long-term stable operation of the system.

This application provides a water purification method applicable to plain water network areas, comprising: (1) investigating and analyzing the hydrodynamic and water quality characteristics of canals in plain water network areas; (2) selecting characteristic degrading microorganisms and immobilizing them on a biological absorption plate; (3) during the dry season, setting up a biological absorption plate mainly composed of anaerobic or facultative anaerobic bacteria inside the canal; (4) during the wet season, setting up a biological absorption plate mainly composed of aerobic or facultative aerobic bacteria on the canal slope; and (5) regularly managing and maintaining the biological absorption plate to ensure long-term water quality maintenance. This method is applicable to the efficient purification of polluted water bodies in canals of plain water network areas under different hydrodynamic conditions, solving the problem of water purification materials hindering flood discharge, and overcoming the problem of microorganisms being unable to effectively attach due to canal hardening. It can rebuild the natural ecology to a certain extent, enhance the self-purification capacity of the water body, and achieve a good ecological landscape and long-term maintenance of water environment quality.

A stent for a respiratory organ includes a bioabsorbable polyester copolymer. The bioabsorbable polyester copolymer is a polyester copolymer having residues of two kinds of ester bond forming monomers as main constituent units, and where the two kinds of ester bond forming monomers are referred to as monomer A and monomer B, respectively, an R value given by the following formula is 0.25 or larger and 0.99 or smaller: R=[AB] / (2[A][B]) 100. In the formula, [A] is a mole fraction (%) of monomer A residues in the polyester copolymer; [B] is a mole fraction (%) of monomer B residues in the polyester copolymer; and [AB] is a mole fraction (%) of structures (A-B and B-A) in which a monomer A residue and a monomer B residue are adjacent to each other in the polyester copolymer.

The present invention relates to a porous nerve guidance conduit produced using a combination of additive manufacturing and rotary jet spinning techniques from any bioabsorbable polymer, wherein the conduit can be incorporated or not with anti-inflammatory drugs. The nerve guidance conduit of the present invention can be used in the field of tissue engineering, in applications and preparations for medical purposes and, more specifically, to repair peripheral nerve injuries.

Embodiments of the present disclosure comprise occlusion and drug delivery devices and methods. One aspect of the disclosure comprises a drug delivery device comprising an inner expansion member and an outer drug delivery component. Another aspect of the disclosure comprises bioabsorbable, lumen-occluding implants.