The present invention relates to a novel biodegradable vascular stent preparation method, which specifically comprises: taking a raw material, heating to achieve a melting state, and cooling to a room temperature to obtain a blank material; adopting a self-made mold, a temperature control device, a heating rod, a clamping device, a data acquisition card, a computer monitoring system and other components to form a set of preparation equipment, paving the blank material in the mold cavity, placing the mold in the clamping device after the blank material achieves a set temperature, tightening the clamping device, and carrying out thermal insulation, cooling, mold opening, polishing and cleaning to obtain a primary stent; and placing the stent in an electrostatic spinning device to carry out electrostatic spinning direct-writing to prepare the composite mesh film stent. The prepared stent has characteristics of degradability, smooth surface and substantially increased mechanical strength, wherein a radial strength of the stent can be effectively enhanced and malformation proliferation hyperplasia of vascular endothelium on the stent can be inhibited with the mesh film. In addition, the whole preparation process is easy and easy to performe, and great practical significances are provided for treatment of cadiovascular or lumen stenosis diseases.