Antiblocking hernia patch and preparation method thereof

An anti-adhesion and hernia repair technology, applied in medical science, surgery, etc., can solve problems such as low anti-infection ability, poor biocompatibility, and easy adhesion of patch, so as to reduce the probability of adverse reactions, prevent adhesion, and increase the number of experiments. volume effect

Inactive Publication Date: 2009-11-18
都本立
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0016] The invention mainly solves the problems of easy adhesion, low repair strength, lo

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Embodiment 1, on the polypropylene braided net, evenly coat the chitosan mucus of one deck viscosity 7500mpa. On the woven net, the composition of the chitosan mucus is the same as the main composition of the chitosan anti-adhesion upper sheet. After lamination, it is placed between the molds and dried by film isolation in an environment of 90°C and 0.3MPa. Obtain an adhesion-resistant hernia repair patch.

Embodiment 2

[0027] Embodiment 2, on the polypropylene braided net, evenly coat the chitosan mucus of one deck viscosity 100mpa. On the woven net, the composition of the chitosan mucus is the same as the main composition of the chitosan anti-adhesion top sheet. After lamination, it is placed between the molds and dried by film isolation in an environment of 150°C and 0.6MPa. Obtain an adhesion-resistant hernia repair patch.

Embodiment 3

[0028] Embodiment 3, on the polypropylene braided net, evenly coat the chitosan mucus of one deck viscosity 15000mpa. On the woven net, the composition of the chitosan mucus is the same as the main composition of the chitosan anti-adhesion upper sheet. After pressing, it is placed between the molds, and it is dried by the film isolation method in the environment of -15°C and 0MPa. Obtain an adhesion-resistant hernia repair patch.

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PUM

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Abstract

The present invention discloses an antiblocking hernia patch and a preparation method thereof. A polypropylene net is combined with an absorptive material chitosan antiblocking piece to prepare a partial absorptive composite mesh. The invention is characterized in that the absorptive material chitosan antiblocking piece is prepared from water-soluble chitosan by a tap casting method. The chitosan phlegm is arranged between the polypropylene net and the absorptive material chitosan antiblocking piece. The preparation method comprises the steps of preparing the chitosan antiblocking piece, uniformly coating one layer of chitosan on the polypropylene woven mesh, then placing the chitosan antiblocking piece on the polypropylene woven mesh, placing the polypropylene woven mesh between the moulds after compressing, and obtaining the antiblocking hernia patch after drying by a film isolation method in the environment at a temperature of between 15 DEG C below zero and 150 DEG C and pressure of 0 to 0.6MPa. The antiblocking hernia patch of the invention has the advantages of effectively preventing the blocking after surgery, increasing the anti-inflection effect, sustaining the excellent repairing strength, reducing the recurrence rate and complication after surgery, reducing the probability of adverse effect caused by the unthorough elimination of acid, simply controlling preparation process and eliminating the adverse effect which may be caused by the chemical process.

Description

Technical field: [0001] The invention relates to the technical field of medical auxiliary materials, in particular to an anti-adhesion hernia repair sheet and a preparation method thereof, which can effectively prevent postoperative adhesion, maintain good repair strength, and reduce postoperative recurrence rate and complications. Background technique: [0002] Hernia, commonly known as a hernia, means that a part of a human tissue or organ leaves its original site and enters another site through a gap, defect or weak part of the human body. There are umbilical hernia, direct inguinal hernia, indirect hernia, incisional hernia, surgical recurrence hernia, white line hernia, femoral hernia and other types. Hernias are mostly caused by coughing, sneezing, excessive force, abdominal fat, straining to defecate, pregnancy in women, excessive crying in children, and degeneration of abdominal wall strength in the elderly. Hernia treatments: [0003] 1. Conservative therapy: [...

Claims

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Application Information

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IPC IPC(8): A61L31/12A61L31/04
Inventor 都本立王成功姜红李颖许文明
Owner 都本立
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