4 results about "Tricine" patented technology

An RGD polypeptide-containing composition and use thereof. The composition contains 1-3 parts by weight of a compound of formula I, 50-200 parts by weight of TPPTS, 2-250 parts by weight of Tricine, and a succinate buffer system, and the amount of the succinate buffer system is such that the pH of the composition is 4.0-7.0. The composition has excellent integrity and stability, and can be used for preparing SPECT imaging agents for tumor diagnosis.

The invention is suitable for the field of molecular biology, and provides an improved electrophoresis liquid and polyacrylamide gel combination and application thereof.The improved electrophoresis liquid is prepared from 25 mM of Tris, 192 mM of glycine, 0.1% (w / v) of SDS and 30-50 mM of Tricine, and polyacrylamide gel is prepared from separation gel and concentrated gel; 30-50 mM of Tricine is added into a traditional formula, an improved electrophoresis solution is prepared, the fringe effect can be reduced by optimizing electric field distribution, 5% (v / v) of glycerin is added into 11%-12% (w / v) of acrylamide / bisacrylamide (29: 1) separation gel, the gel stability is enhanced, the heat effect and pore deformation are reduced, CV is reduced to 5-6% through improved combination, and the transfer efficiency is improved to gt; the method is especially suitable for 15-100 kDa protein analysis.

Disclosed are cationic lipids which are compounds of Formula A. (A) Cationic lipids provided herein can be useful for delivery and expression of mRNA and encoded protein, e.g., as a component of liposomal delivery vehicle, and accordingly can be useful for treating various diseases, disorders and conditions, such as those associated with deficiency of one or more proteins. X2A X1A X4A X3A X1B n n n X2B O X3BO X4B O R2 R4 R3 R1 O X3A O O X1A X 1B 20 26 20 48 02 22 J un 2 02 6 2 0 2 6 2 0 4 8 0 2 2 2 2 0 2 6 J u n O O O 1 A 1 B

The present invention provides, in part, tricine and citrate lipids, or pharmaceutically acceptable salts thereof. The compounds provided herein, comprising compounds of formula (A), may be useful for the delivery and expression of mRNA and encoded proteins, for example, as components of liposome delivery vehicles, and therefore may be useful in treating a variety of diseases, disorders and conditions, including those associated with the deficiency of one or more proteins. [Case 1] TIFF2026524782000711.tif22170