73results about How to "Negatively affected" patented technology

A method and apparatus that utilizes a force-time integral for real time estimation of lesion size in catheter-based ablation systems. The apparatus measures the force exerted by a contact ablation probe on a target tissue and integrates the force over an energization time of the ablation probe. The force-time integral can be calculated and utilized to provide an estimated lesion size (depth, volume and / or area) in real time. The force-time integral may also account for variations in the power delivered to the target tissue in real time to provide an improved estimation of the lesion size. In one embodiment, the force metric can be used as feedback to establish a desired power level delivered to the probe to prevent steam popping.

The invention relates to a method and apparatus for determining a chemical component from a sample, where the sample is measured on a test strip with the help of a color reaction. The method concerns finding the measurement time Tm for measuring the reflection of the test strip. The method comprises the following steps: a) Recording the R(t) function, b) Determining the T0 starting time at the detection of the wetting through of the sample, c) Generating the function R(t)+L(t), d) Monitoring and storing the ext[R(t)+L(t)] extreme value of the R(t)+L(t) function, and, at the same time, e) Generating the function R(t)+L(t)-ext[R(t)+L(t)] from the time of reaching an ext[R(t)+L(t)] extreme value, f) when the R(t)+L(t)-ext[R(t)+L(t)] function reaches a predetermined C(t) value, determining the Tm measuring time.

A frame ensures that the alignment between a high intensity focused ultrasound (HIFU) transducer designed for vaginal use and a commercially available ultrasound image probe is maintained, so that the HIFU focus remains in the image plane during HIFU therapy. A water-filled membrane placed between the HIFU transducer and the treatment site provides acoustic coupling. The coupling is evaluated to determine whether any air bubbles exist at the coupling interface, which might degrade the therapy provided by the HIFU transducer. HIFU lesions on tissue appear as hyperechoic spots on the ultrasound image in real time during application of HIFU therapy. Ergonomic testing in humans has demonstrated clear visualization of the HIFU transducer relative to the uterus and showed the potential for the HIFU transducer to treat fibroids from the cervix to the fundus through the width of the uterus.

A method for manufacturing a ferroelectric memory includes the steps of forming a driving transistor on a semiconductor substrate, forming a first interlayer dielectric film that covers the driving transistor on the semiconductor substrate, forming a first hydrogen barrier film on the first interlayer dielectric film, and forming a ferroelectric capacitor electrically connected to the driving transistor on the first hydrogen barrier film, wherein hydrogen sintering treatment is conducted between the step of forming the driving transistor and the step of forming the first hydrogen barrier film.

The present invention further provides insight into the mechanism of action of immunotoxins in disease states such as hyperproliferative disease states. The present invention provides a novel method of treating diseases using immunotoxins and gene expression profiling to identify genes that are modulated by immunotoxin therapy.

The present invention relates to a novel method of treating male infertility such as, for example, idiopathic asthenospermia. In one aspect the present invention relates to the treatment or prevention of male infertility through the administration of a composition containing ubiquinone, ubiquinol or both, and optionally, a member chosen from the group consisting of a reducing agent, a solubilizer, an emulsifier, a surfactant, a triglyceride, an oil, a fat, a lipid, a phospholipid, a carbohydrate, an antioxidant, a carnitine, creatine, an herbal extract, a vitamin, a coenzyme, a mineral, an electrolyte, a pharmaceutical, a water, a carrier, an excipient, and any combination thereof.

Insulating element from mineral fibers for shipbuilding with an insulating element in form of a plate or roll felt for shipbuilding the composition of the mineral fibers of the insulating element points an alkali / alkaline-earth mass ratio of the fiber structure of the insulating element is determined by an average geometrical fiber diameter of ≦4 μm and a surface weight of 0.8 through 4.3 kg / m2 and a binding agent portion above 0.5 until 4 weight %.

A method for electrochemically depositing discrete regions of calcium phosphate onto a medical implant. The method includes providing an implant including at least one area having a metallic surface. At least a portion of the metallic surface is contacted with an electrolyte solution comprising calcium ions and phosphate ions. The metallic surface is used as a cathode, and an electrical potential is applied between the cathode and the electrolyte solution. The electrical potential is applied with a constant current density of from about 10 to about 50 mA / cm2 for a period of time of from about 1 to about 20 minutes. A plurality of discrete regions of needle-shaped hydroxyapatite crystals are electrochemically deposited onto the metallic surface.

A methodology is disclosed that enables the delay stages of an analog delay locked loop (DLL) or phase locked loop (PLL) to be programmed according to the operating condition, which may depend on the frequency of the input reference clock. The resulting optimized delay stages allow for a broad frequency range of operation, fast locking time over a wide range of input clock frequencies, and a lower current consumption at high clock frequencies. Better performance is achieved by allowing the number of analog delay stages active during a given operation to be flexibly set. The deactivation or turning off of unused delay stages conserves power at higher frequencies. The high frequency range of operation is increased by using a flexible number of delay stages for various input clock frequencies. Because of the rules governing abstracts, this abstract should not be used to construe the claims.

A method and apparatus that utilizes a force-time integral for real time estimation of steam pop in catheter-based ablation systems. The apparatus measures the force exerted by a contact ablation probe on a target tissue and an energization parameter delivered to the ablation probe. The exerted force and energization parameter can be utilized to provide an estimation of the probability of steam pop. In one embodiment, the force and energization metrics can be used as feedback to establish a desired contact force and energization level combination to prevent steam popping.

A piezoelectric energy harvesting system for converting mechanical energy of a tire of a vehicle to electrical energy includes sets of piezoelectric beam assemblies, a tire electrical jack, a conductive bearing, and an electrical storage unit. The sets of piezoelectric beam assemblies are embedded in multiple layers of the tire of the vehicle and electrically connected in a parallel configuration. Each of the sets of the piezoelectric beam assemblies are electrically connected in a series configuration for converting mechanical strains into electrical energy. The tire electrical jack is mounted on a rim of the tire and receives the electrical energy generated by the sets of piezoelectric beam assemblies via output terminals. The conductive bearing transmits the electrical energy received by the tire electrical jack to the electrical storage unit, which filters, rectifies, adapts and stores the transmitted electrical energy for powering components of the vehicle.

A fuel delivery system is provided to reduce the pressure pulsations and noise vibration and harshness of direct injection systems. The fuel delivery system includes an elastic fuel line positioned between a first fuel pump and a second fuel pump and a check valve positioned in the elastic fuel line near the inlet of the high pressure pump, the check valve including an external housing having a peripheral surface with a greater diameter than an unstretched inner diameter of the elastic fuel line.

A gas spring comprises a cylindrical casing, in which a piston rod is guided for displacement concentric of a central longitudinal axis. A damping piston is mounted on the piston rod, dividing the interior of the casing into two sectional casing chambers. A filling of compressed gas is provided inside the casing. A damping device is provided for velocity-dependent damping of a motion of stroke of the damping piston and another damping device is provided for path-dependent damping of a motion of stroke of the damping piston. The result is a gas spring of excellently controllable stroke behaviour.

A methodology is disclosed that enables the delay stages of an analog delay locked loop (DLL) or phase locked loop (PLL) to be programmed according to the operating condition, which may depend on the frequency of the input reference clock. The resulting optimized delay stages allow for a broad frequency range of operation, fast locking time over a wide range of input clock frequencies, and a lower current consumption at high clock frequencies. Better performance is achieved by allowing the number of analog delay stages active during a given operation to be flexibly set. The deactivation or turning off of unused delay stages conserves power at higher frequencies. The high frequency range of operation is increased by using a flexible number of delay stages for various input clock frequencies. Because of the rules governing abstracts, this abstract should not be used to construe the claims.

During RNA isolation carrier nucleic acids such as polyA-RNA are used in order to increase the yield of the isolated RNA. The carrier nucleic acids may lead to high molecular weight products which may interfere in subsequent steps, such as reverse transcription, PCR and gel electrophoresis. The present invention therefore refers to a method and a kit for reverse transcription and the use of a blocking nucleic acid molecule for blocking the carrier polyA-RNA.

Dynamic interface management for interference mitigation is disclosed. In one aspect, an integrated circuit (IC) is provided that employs a control system configured to mitigate interference caused by an aggressor communications bus. The control system is configured to receive information related to interference conditions and adjust a data / clock mode of an interface corresponding to the aggressor communications bus. In this manner, the interface is configured to couple to the aggressor communications bus. The interface is configured to transmit signals to and receive signals from the aggressor communications bus. The control system is configured to use the information related to the interference conditions to set the data / clock mode of the interface to mitigate the interference experienced by a victim receiver, whether the victim receiver is wired or wireless. Thus, the control system provides designers with an additional tool that may reduce performance degradation of the victim receiver attributable to the interference.

The present invention is directed to oligonucleotides based on peptide nucleic acid oligonucleotide or an equivalent oligonucleotide analogue, such as morpholino or a locked nucleic acid sequences and the use of such oligonucleotides for the dissociation of higher order structures, including triplex-helix DNA structures, in repeated sequences of DNA in Friedreich's ataxia. The dissociation of such structures may be used in the diagnosis and / or treatment of Friedreich's ataxia. Consequently, the present invention is also directed to a method for diagnosing Friedreich's ataxia and the use of peptide nucleic acid oligonucleotide or an equivalent oligonucleotide analogue, such as morpholino or a locked nucleic acid sequences in the treatment of Friedreich's ataxia. Preferably, the oligonucleotides comprise a sequence selected from the group consisting of (GAA)n, (CTT)n, (JTT)n or a mixed (JTT / CTT)n sequence.

A power transmitter (101) for a wireless power transfer system comprises a transmitter coil (103) and a driver (201) generates a drive signal) for the transmitter coil (103) employing a repeating time frame with a power transfer time interval and a reduced power time interval during which a power level of the power transfer signal is reduced. A driver (201) generates a drive signal for the transmitter coil (103) to generate the power transfer signal. A communicator (205) receives messages from the power receiver (105) and an adapter (213) adapts a timing property of the reduced power time interval in response to at least a first message received from the power receiver (105). A synchronizer (206) for synchronizing a foreign object detection and the generation of a test signal to occur during the reduced power time interval. The operation may typically be a foreign object detection or communication, and the timing property may e.g. be a duration of the reduced power time interval.

Dynamic interface management for interference mitigation is disclosed. In one aspect, an integrated circuit (IC) is provided that employs a control system configured to mitigate electromagnetic interference (EMI) caused by an aggressor communications bus. The control system is configured to receive information related to EMI conditions and adjust a data / clock mode of an interface corresponding to the aggressor communications bus. In this manner, the interface is configured to couple to the aggressor communications bus. The interface is configured to transmit signals to and receive signals from the aggressor communications bus. The control system is configured to use the information related to the EMI conditions to set the data / clock mode of the interface to mitigate the EMI experienced by a victim receiver. Thus, the control system provides designers with an additional tool that may reduce performance degradation of the victim receiver attributable to EMI.

An aspirator includes a pump, a detecting unit, and a control unit. The pump is driven by a piezoelectric element and has a suction portion and a discharge portion. The detecting unit includes a current detector and a regulator, and detects a closed state of the suction portion. The control unit includes the regulator and a voltage controller, and regulates an output voltage for the piezoelectric element in accordance with the closed state of the suction portion detected by the detecting unit.

A working vehicle includes an engine mounted in a front portion of a travelling vehicle, and a post-processing device configured to purify exhaust gas from the engine. The engine and the post-processing device are covered with a hood. An upper surface side of the hood is inclined to extend diagonally upward from a front side to a rear side. The post-processing device is mounted on an upper side of the engine, and is positioned on a rear and inner side of the inclined upper surface side of the hood.

A method for automatically collecting payment for a credit account includes determining if a credit account is delinquent and determining the number of days the credit account is delinquent. The method includes automatically collecting a first amount from a first account if the number of days the credit account is delinquent comprises at least a first number of days and crediting the credit account the first amount. The first account may comprise a checking account, and the first number of days may comprise twenty days.

Insulating element from mineral fibers for shipbuilding with an insulating element in form of a plate or roll felt for shipbuilding the composition of the mineral fibers of the insulating element points an alkali / alkaline-earth mass ratio of the fiber structure of the insulating element is determined by an average geometrical fiber diameter of ≦4 μm and a surface weight of 0.8 through 4.3 kg / m2 and a binding agent portion above 0.5 until 4 weight %.

A wide, flat-bottom, buoyant, amphibious hull with a powered articulating member mounted on the deck. The hull is propelled by at least one engine-driven propeller rotating above the hull. The hull has a shallow draft and distributes its weight over a large area. These features cooperatively provide a vehicle capable of installing or servicing power transmission poles, towers, or other structures located in environmentally sensitive wetlands, swamps, marshes, shallow water, or terrain which is not efficiently accessible by other means.