26 results about "Charged polymers" patented technology

The invention discloses a charged hollow fiber loose nanofiltration membrane as well as a preparation method and application thereof. The hollow fiber nanofiltration membrane comprises a supporting layer and a charged separation layer, and the charged separation layer is attached to the inner surface of the hollow fiber supporting layer and is co-extruded and molded by adopting a double-layer spinneret plate; the charge separation layer comprises a charge polymer and a matrix polymer, and a positively charged polymer or a negatively charged polymer is selected according to an entrapment dye; the negatively charged separation layer further comprises hydroxylated polyether sulfone; the charged hollow fiber loose nanofiltration membrane is prepared by preparing an inner-layer membrane casting solution and an outer-layer membrane casting solution, carrying out co-extrusion molding through a double-layer spinneret plate, carrying out phase inversion membrane formation and then carrying out post-treatment. During application, corresponding charged nanofiltration membranes can be selected according to the electrical properties of dyes in sewage, efficient selective interception of different charged dyes is achieved, meanwhile, high transmittance is achieved for inorganic salt, the technological process of a one-step continuous forming process is simplified, the production efficiency is high, the method can be compatible with an existing hollow fiber membrane production line, and industrialization is easy to achieve.

Charged polymeric webs, such as electret webs, include a thermoplastic resin and a charge-enhancing additive. The additives are substituted heterocyclic thiolate salts. The heterocyclic thiolate salt has 2 nitrogen groups and a third group that may be an NH, N—NH2, O, or S group. The substituent group is an aromatic or heterocyclic aromatic group. The electret webs may be a non-woven fibrous web or a film. The electret webs are suitable for use as filter media.

The invention discloses a soybean protein-phospholipid biomimetic membrane as well as a preparation method and application thereof. The biomimetic membrane is formed by three raw materials of soybean protein, soybean lecithin and a charged polymer through electrostatic interaction and a physical blending method. The soybean 11s protein solution, the lipidosome dispersion liquid and the charged polymer solution are mixed to obtain the mosaic structure biomimetic membrane which is formed by combining various chemical bond crosslinking and electrostatic interaction, and the process conditions are simple, efficient, convenient and environmentally friendly. The biomimetic membrane provided by the invention has a mosaic structure and the characteristics of the raw materials, so that the biomimetic membrane has high ion passing rate, strong ion selection capability, excellent monovalent cation and divalent cation separation capability and certain biodegradability. When the biomimetic membrane is applied to ion separation, the separation capacity of ions with different valence states can be effectively improved, the separation effect of sodium ions and magnesium ions is optimal, and the separation factor is as high as 21.28 and is 54.6 times that of a biomimetic membrane without charges.

The present invention provides methods for characterizing the composition of polymers. Common to these methods, the subunits of a charged polymer strand are moved by the force of electrophoresis across closely spaced electrodes so as to produce tunneling currents modulated by their passage and indicative of their chemical structure. Comparisons of the electronic signals thus obtained to those of known standards that have undergone similar electrophoresis are made so as to determine the composition of the polymer and the linear sequence of its subunits.The invention described here may be used for: the detection and identification of biological agents that may be pathogenic; the sequencing of small linear RNAs that may be present in cells and those that have been linearized by the methods described herein; and the sequencing of linear genomic DNA, mRNAs, linear non-coding RNAs, and polypeptides.

The utility model relates to a kind of packaging structure of fast-charging polymer lithium ion battery, comprising: battery main body, the upper end of which is equipped with tab;Protection plate, is located in the upper end of the battery main body, the lower end surface of the tab is electrically connected after being bent;Plastic package part, is covered in the outside of the protection plate and tab;And connecting piece, with the upper end surface of the protection plate fixed connection, the connecting piece is bent and extends to the side of the battery main body after extending outwards and passing through the plastic package part, and is connected with the side of the battery main body.The utility model can connect the upper end surface of protection plate with the side of battery main body, form support, guide and disperse the stress on the tab of existing plastic package structure to the side of more stable battery main body, to enhance the overall stability and reliability of plastic package structure.

A polymeric delivery system delivers a biologic to cells. In some embodiments, the polymeric delivery system includes polyplexes. Each polyplex includes at least one charged polymer and at least one biologic. The at least one charged polymer includes a polyester copolymer of a polyol and a polycarboxylic acid modified with at least one charged moiety having an opposite charge from a net charge of the at least one biologic. In other embodiments, the polymeric delivery system includes self-assembled particles including a block copolymer and a biologic associated with the block copolymer. The block copolymer includes a first block of a polyester copolymer of a polyol and a polycarboxylic acid and a second block of a second monomer or a second polymer.

In the present invention, positively charged cerium hydroxide particles without undergoing surface charge treatment are subjected to ultrasonic agitation, so that a negatively charged polymer or monomer and the cerium hydroxide particles form a coordination bond, thereby forming a first surface coating layer and reversing the surface charge into a negative charge; and in a second coating step, a weakly positively charged polymer is added, so that by means of charge attraction, a polymeric ion pair is formed, thereby achieving a second charge reversal to a positive charge. Disclosed in the present invention is a method for multiple surface coatings of cerium hydroxide particles. The coated cerium hydroxide particles do not change the intrinsic electrical properties thereof, and can greatly reduce defects caused by mechanical forces during polishing, such as particle adhesion, thereby improving the product yield.

This invention relates to a monovalent selective anion exchange membrane, its preparation method, and its application. The preparation method includes the following steps: placing the anion exchange base membrane in an electrodeposition solution for electrodeposition; the electrodeposition solution includes a negatively charged polymer and a neutral salt; then placing it in an oxidant solution for a chelation reaction; and finally placing it in a polymer monomer solution for polymerization to obtain the monovalent selective anion exchange membrane. This invention, through sequential electrodeposition, chelation, and polymerization reactions, utilizes the active sites formed by the chelation reaction between the negatively charged layer and the oxidant to regulate the directional polymerization of the polymer, forming a dense polymer-modified layer. This avoids polymer clogging of the anion exchange base membrane pores, achieving high ion selectivity, effectively weakening the trade-off effect between flux and selectivity of the monovalent selective anion exchange membrane, and exhibiting good antifouling performance.

A biologic composition for promoting wound healing includes: a human mesenchymal stem cell (MSC)-derived extracellular matrix (ECM) biologic component, and a negatively charged polymer, combined with the biologic component to form the biologic composition. A method of preparing the biologic composition thereof includes: (i) isolating human mesenchymal stem cells (MSC) and subjecting the MSC to hypoxia-priming in a xeno- and / or serum-free, or chemically defined medium to stimulate the production of an MSC-derived biologic component with pro-angiogenic factors; (ii) aggregating and co-precipitating the MSC-derived biologic component with a negatively charged polymer into a pericellular space of the MSC to produce an aggregated biologic component; (iii) assembling the aggregated biologic component and the negatively charged polymer into an insoluble extracellular matrix (ECM) by the MSC; and (iv) decellularizing the insoluble ECM to obtain the biologic composition comprising MicroParticles of Solidified Secretome (MIPSOS).

The invention discloses a negative plate with a directional gradient pore structure, a composite pore-forming agent for preparing the negative plate, a preparation method and a lithium ion battery, the composite pore-forming agent has a core-shell coating structure and a surface functionalization modification layer, the core-shell coating structure comprises an inner core and an outer shell coating the outer surface of the inner core; wherein the inner core is a thermal decomposition type pore-forming material, and the thermal decomposition type pore-forming material can be subjected to thermal decomposition in a temperature range of 80-120 DEG C and release gas; the shell is a thermal dissolution type polymer coating layer, and the surface functionalization modification layer is a charged polymer layer and uniformly coats the outer surface of the shell, so that the composite pore-forming agent is endowed with surface charge characteristics. According to the invention, the composite pore-forming agent combining core-shell coating and surface functional modification is designed and is matched with an electric field-assisted gradient sedimentation and segmented heating pore-forming process, so that directional gradient regulation and control of a pore structure in the thickness direction of the pole piece are realized in a single pore-forming agent system.

This application discloses a method and apparatus for preparing formaldehyde-free decorative paper impregnated with aqueous polyacrylate, belonging to the field of decorative paper production technology. The method includes: providing continuously running formaldehyde-free decorative paper; establishing an asymmetric pulsed electric field within a reactor impregnated with an aqueous polyacrylate emulsion along the path of the formaldehyde-free decorative paper; and controlling the formaldehyde-free decorative paper to pass through the reactor, so that negatively charged polymer micelles in the aqueous polyacrylate emulsion, under the action of the asymmetric pulsed electric field, overcome electrostatic repulsion and surface tension, and are forcibly and rapidly penetrate and fill the internal fiber network of the formaldehyde-free decorative paper. This application fundamentally solves the technical problem of the difficulty in deeply and uniformly impregnating the base paper with environmentally friendly aqueous resin under high-speed production conditions by introducing an electrodynamic forced penetration mechanism.

A polymeric delivery system delivers a biologic to cells. In some embodiments, the polymeric delivery system includes polyplexes. Each polyplex includes at least one charged polymer and at least one biologic. The at least one charged polymer includes a polyester copolymer of a polyol and a polycarboxylic acid modified with at least one charged moiety having an opposite charge from a net charge of the at least one biologic. In other embodiments, the polymeric delivery system includes self-assembled particles including a block copolymer and a biologic associated with the block copolymer. The block copolymer includes a first block of a polyester copolymer of a polyol and a polycarboxylic acid and a second block of a second monomer or a second polymer.

A nucleic acid detection method comprises the steps of: inputting a sample containing nucleic acids into a vessel coated with a thin film comprising a cationic polymer having a hydrolyzable side chain; forming a polymer-nucleic acid complex by binding the nucleic acids to the cationic polymer which has been dissolved from the thin film; releasing the nucleic acids from the polymer-nucleic acid complex by hydrolyzing the cationic polymer; and amplifying the nucleic acids or other nucleic acids synthesized from said nucleic acids. The nucleic acid detection method may be carried out in a single pot, may reduce the detection time, and may improve detection accuracy.

The invention provides an oral drug delivery system and application thereof in the field of PAL delivery. According to the invention, DMSN-loaded PAL is taken as a core and is self-assembled with different charged polymers layer by layer through electrostatic interaction, the surface of the core is coated with a multi-layer polymer coating, and then nano-particles are encapsulated by adopting enteric capsules, so that the nano-particles can pass through the stomach to reach the small intestine absorption part in a complete particle form. An oral PAL delivery system which is stable in structure and synergetic in function is constructed. According to the PAL oral delivery system provided by the invention, the resistance of the PAL oral delivery system in intestinal tracts is enhanced, the penetrability of a mucous layer loaded with the PAL is improved, the complex environment in gastrointestinal tracts can be overcome, the PAL oral delivery system is transferred to blood through intestinal epithelial cells to play a role, and good bioavailability and biocompatibility are shown. The method is free of chemical modification, the preparation method is simple, reaction conditions are mild, use of toxic chemical reagents and potential damage to PAL enzyme activity are avoided, and a new PAL administration mode is provided.

This application provides surface-charged polymer nanoparticles, their synthesis method, and applications. The synthesis method for the charged polymer nanoparticles includes: adding a thiocarbonate chain transfer agent, a charged monomer, an aromatic monomer containing at least two benzene rings, and an initiator to a mixture of water and an organic solvent to obtain a mixture; heating the mixture in a vacuum-sealed environment, and obtaining surface-charged polymer nanoparticles through a polymerization reaction and self-assembly process, wherein the charged monomer is a monomer with a single charge type.

The application discloses a composite sodium-ion positive electrode material and a preparation method thereof; in the preparation, iron-based Prussian blue FeHCF is prepared through co-precipitation, and then a polyanion shell is coated through hydrothermal reaction; the inner core of the prepared Prussian blue is surface-modified, the surface modification comprises the following steps: using a positively charged polymer to make the surface of the Prussian blue positively charged through electrostatic adsorption, or using a coupling agent to introduce functional groups such as amino groups, so that the adsorption capacity of the surface of the Prussian blue to polyanion precursor ions is enhanced, and the growth of a uniform and dense shell is promoted. In the composite structure positive electrode material with the core of Prussian blue and the shell of polyanion provided by the application, the inner core Prussian blue plays a role in high capacity and excellent rate performance; the outer shell polyanion mainly plays a role in physical barrier and stable interface, the stable structure and excellent cycle performance of the polyanion material are used to provide a solid 'protective shell' for the whole particle, reduce the structural damage in the cycle process, and improve the overall cycle life.

Electrochemical biosensors are described, such as inverted molecular pendulums (iMP) comprising a charged polymer bound to a receptor and to a redox reporter, wherein the iMP is operationally affixed to an electrode. The electrochemical biosensors are configured to detect analytes, such as analytes present in biological or other fluids. Also described are biosensor devices comprising such biosensors, and methods of using the biosensors and devices to detect the analytes.

The invention provides a method for reducing arc defects in a high aspect ratio process. The method is applied to wet cleaning of a wafer subjected to dry etching, and comprises the following steps: carrying out first cleaning treatment on the wafer by adopting a first cleaning solution with low conductivity, forming a thick liquid film by reducing the rotating speed to physically disperse an electrified polymer, and throwing pollutants away from the wafer by increasing the rotating speed; and carrying out second cleaning treatment on the wafer by adopting second cleaning liquid with the conductivity higher than that of the first cleaning liquid so as to guide away residual charges on the surface. According to the method, through a two-step charge release strategy of'physical stripping first and then electrical neutralization ', surface charges are mildly and gradually removed, the charge release rate is effectively controlled, arc defects caused by instantaneous discharge are avoided, the defect rate is reduced, the product yield is improved, the process compatibility is good, and additional hardware cost does not need to be increased.

The invention relates to a method for powder coating a component, comprising: a providing step in which the component and a coating powder having polymer particles and an additive are provided; an electrical loading step in which the coating powder particles are provided with an electrical charge; a dispersion step in which the electrically loaded polymer particles are mixed with a dispersion liquid to form a dispersion; an application step in which the dispersion is in contact with a surface of the component, with evaporation of the dispersion liquid and deposition of polymer particles on the surface, the surface being electrically loaded and / or negatively charged and / or grounded in contrast to the electrically loaded polymer particles, and wherein the surface has a surface temperature higher than the boiling point of the dispersion liquid; and a fusion step in which the component and / or the polymer particles deposited on the surface are heated by means of a heat source such that the polymer particles are fused and / or foamed and / or expanded with each other, forming a polymer coating arranged on the surface of the component.

A high-efficiency, humidity-stable perovskite solar cell that synergistically improves defects and ion migration, comprising a perovskite active layer, wherein the chemical formula of the perovskite material is FA. x MA y Cs z PbX3, x+y+z=1, where X is selected from one, two, or three elements from I, Br, and Cl; the perovskite active layer also contains a variable-valence material. This invention uses a variable-valence material as an additive in the perovskite precursor solution, utilizing cation passivation of Pb. 0 I 0 Defects, anions and uncoordinated Pb 2+ Defects can improve the phase stability of perovskite crystals; further, positive / negative charged polymers can be used for double-sided passivation on both sides of the perovskite film, utilizing the positive / negative charged polymers to passivate oxygen vacancies and Pb. 2+ Defects such as these are eliminated, and ion migration at the interface is also blocked; the perovskite solar cell device of the present invention has both high photoelectric conversion efficiency and high humidity stability.

The application discloses a kind of nano-carrier based on charge crosslinking and its preparation method and as the application of tumor chemotherapy drug.Therein, nano-carrier is assembled by the electrostatic interaction of two polymer chains with positive and negative charges, and the organic ligand is released under exogenous or endogenous stimulation by the pre-ligand on polymer chain B, and metal ions on positive charge polymer chain A are competed, and metal complex is generated in situ, while the electrostatic interaction of nano-carrier is weakened, leading to the dissociation of nano-carrier, and the release of polymer chain B containing organic ligand, playing the role of tumor chemotherapy or immunoregulation.The method is simple in operation, short in time consumption and mild in reaction conditions;The material has good biocompatibility and high safety.In some embodiments, pharmacodynamic experiments show that the nano-carrier can effectively kill breast cancer and induce cell immunogenic death, while inhibiting the metastasis of tumor cells, providing a new idea and means for the current urgent clinical problem of breast cancer lung metastasis.

The invention relates to a method for powder coating a component, comprising a provision step in which the component and a coating powder comprising polymer particles and additives are provided, an electrical charging step in which the coating powder particles are provided with electrical charges, a dispersion step in which the electrically charged polymer particles are mixed with a dispersing liquid to form a dispersion, and an application step in which the dispersion is brought into contact with the surface of the component by evaporating the dispersing liquid and depositing the polymer particles, wherein the surface is electrically oppositely and / or negatively charged and / or grounded compared to the electrically charged polymer particles, and wherein the surface has a surface temperature that is above the boiling point of the dispersing liquid.as well as a fusion step in which the component and / or the polymer particles deposited on the surface are heated by means of a heat source, so that the polymer particles fuse together and / or foam up and / or expand, forming a polymer coating arranged on the surface of the component.

A biological composition for promoting wound healing includes: a human mesenchymal stem cell (MSC)-derived extracellular matrix (ECM) biological component; and a negatively charged sulfated polymer; wherein the negatively charged polymer is combined with the biological component to form the biological composition. A method of preparing a biological composition for promoting wound healing comprises: (i) isolating human mesenchymal stem cells (MSCs) and subjecting the MSCs to hypoxia pretreatment in a culture medium to stimulate secretion of MSC-derived biological components containing pro-angiogenic factors; (ii) aggregating and co-precipitating the MSC-derived biological component with a negatively charged polymer in the pericellular space of the MSC to produce an aggregated biological component; (iii) assembling, by the MSC, the aggregated biological component and the negatively charged polymer into an insoluble ECM; and (iv) subjecting the insoluble ECM to a decellularization treatment to obtain the biological composition comprising solidified secretory group microparticles (MIPSOS). The biological composition exhibits excellent therapeutic efficacy, in particular, faster wound healing speed and stronger angiogenic bioactivity.

This application relates to the field of working reference reagents, specifically disclosing a method for improving the quality of disodium ethylenediaminetetraacetate (EDTA), comprising the following steps: dispersing crude EDTA in water, adjusting the pH of the system, adding sodium carbonate to induce salt precipitation, adding a negatively charged polymer and stirring, allowing it to stand, adding activated carbon for adsorption, filtering to obtain a filtrate, wherein the negatively charged polymer includes one or more of sodium polyacrylate, polyaspartic acid, sodium polystyrene sulfonate, and sodium alginate; ultrafiltration of the filtrate obtained in step I, and adding anhydrous ethanol to the resulting liquid phase, controlling the volume ratio of anhydrous ethanol to filtrate to be 1.5:(2-4.5); stirring and filtering; drying the resulting filter residue to obtain disodium EDTA. The method of this application involves multiple interconnected steps, forming a rigorous and streamlined overall scheme, which improves the purity of disodium EDTA to 99.5% or higher.

The invention discloses a bottle-brush-shaped polymer, anti-adhesion hydrogel and application of the bottle-brush-shaped polymer and the anti-adhesion hydrogel, and belongs to the technical field of polymer chemistry and biomedical materials.The bottle-brush-shaped polymer is prepared from poly (L-glutamic acid) modified by an ATRP initiator and an acrylate monomer, and after the bottle-brush-shaped polymer is further subjected to zwitterionic ionization, the anti-adhesion hydrogel is obtained. The zwitterionic bottle-brush-shaped polymer and the negatively-charged polymer can realize the preparation of the anti-adhesion hydrogel through the ionic interaction, and the anti-adhesion hydrogel has the characteristics of rapid gelation, injectability and self-healing property, is convenient to apply to irregular wounds, has good degradation performance, and has wide application prospects in the field of biomedical materials.

The invention provides a preparation method of a modified polyethylene and aramid fiber composite bonding material, and belongs to the field of high-performance polymer composite materials. Comprising the following steps: preparing a base material A: preparing maleic anhydride grafted modified polyethylene; preparation of a base material B: sequentially cleaning and drying aramid fibers, and immersing the dried aramid fibers in a sodium hydroxide solution for surface activation to obtain surface activated aramid fibers; preparation of a bonding layer C: heating and melting polyether ester, adding a cationic polymer, stirring and dispersing uniformly, sequentially adding a phenolic coupling agent and grafted tackifying resin, and mixing to obtain a composite adhesive; and performing composite molding: melting the composite adhesive, coating the composite adhesive on the surface of a base material A or a base material B, laminating the base material A and the base material B, and performing hot pressing treatment to obtain the modified polyethylene and aramid fiber composite adhesive material. Through the electrostatic adsorption capacity of the charged polymer, the bonding interface is firmer; the peeling strength is obviously improved.