97 results about "Charged polymers" patented technology

The invention provides a composition for grinding and a method for carrying out chemical mechanical grinding on a base material, and relates to the technical field of chemical reagents for semiconductor manufacturing. The composition for grinding comprises aluminum oxide abrasive particles with the average primary particle size of 80-140 nm, a first polymer, a second polymer and a pH regulator, the first polymer is a negatively charged polymer or copolymer, and the pH value of the composition for grinding is 8-10. By adding the first polymer and the second polymer, the first polymer coats the surfaces of the aluminum oxide abrasive particles to improve the stability of the composition for grinding, and the second polymer generates weak adsorption on the surfaces of coating layers of the aluminum oxide abrasive particles to prevent agglomeration of various abrasive particles and further stabilize the system. Under the combined action of the first polymer and the second polymer, the aluminum oxide abrasive particles can be stably dispersed in the grinding composition with the pH value of 8-10, and the storage time of the grinding composition can be prolonged under the condition of ensuring that the grinding composition has better grinding performance.

The invention discloses a flexible anti-fouling and anti-drag composite coating with temperature responsiveness and a preparation method and application of the flexible anti-fouling and anti-drag composite coating. The flexible antifouling anti-drag composite coating comprises a substrate layer, a flexible buffer layer, an antifouling response layer and a hydrophobic surface layer which are sequentially formed on the surface of a base material, wherein the substrate layer comprises adhesive resin, a positively charged polymer and a particle filler; the flexible buffer layer comprises flexible polymer resin, a negatively charged polymer, a polymer drag reducer and an anti-ultraviolet additive; the hydrophobic surface layer comprises flexible polymer resin, a temperature-responsive polymer microcapsule encapsulated with an antifouling agent, a pore-foaming agent, an anti-ultraviolet additive and super-hydrophobic micro-nano particles. The flexible anti-fouling and anti-drag composite coating with temperature responsiveness provided by the invention has strong binding force with a base material, and also has anti-fouling property, corrosion protection property and anti-drag property; meanwhile, the preparation method provided by the invention has the advantages of wide application range, large-area coating and the like.

The present invention belongs to the technical field of sewage treatment. Disclosed are a biological carrier for enhancing enrichment and activity of anaerobic ammonium oxidation bacteria, a preparation method therefor, and a use thereof. In the present invention, a functional biological carrier suitable for anaerobic ammonium oxidation is prepared by blending polyethylene or polypropylene as a basic raw material, a positively charged polymer such as a polyquaternary ammonium salt or a cationic polyacrylamide as a modifying material, and zero-valent iron and a carbon-based material containing C=O and -COOH functional groups as functional materials. The biological carrier of the present invention can enhance the enrichment and metabolic activity of the anaerobic ammonium oxidation bacteria, thereby improving the nitrogen removal efficiency.

The invention discloses a multifunctional coating with a compact-porous double-layer structure on the surface of magnesium alloy and a preparation method, and belongs to the technical field of biological materials. According to the multifunctional coating, magnesium alloy serves as a substrate, a compact layer and a porous layer are sequentially stacked from the substrate to the outside, and the compact layer is composed of two-dimensional transition metal carbide / nitride, calcium silicate nanowires and a positively charged polymer. The porous layer is composed of copper-containing complex / biopolymer composite fibers, mineralized silk fibers loaded with bioactive metal ions and astragalus polysaccharide on the surface, and natural polymers. According to the multifunctional coating with the compact-porous double-layer structure prepared on the surface of the magnesium alloy, the porous layer on the surface layer has a unique porous structure, growth and proliferation of osteoblasts can be well promoted, meanwhile, the multifunctional coating has the characteristics of pressure resistance, bacteria resistance and oxidation resistance, the compact layer on the bottom layer can improve the corrosion resistance of the magnesium alloy, and the service life of the magnesium alloy is prolonged. The coating is particularly suitable for surface coating of magnesium alloy implant materials and can be used in the field of medical instruments.

The invention discloses an anti-corrosion, anti-fouling and anti-drag composite coating as well as a preparation method and application thereof. The anti-corrosion, anti-fouling and anti-drag composite coating comprises a substrate layer, a corrosion blocking layer, a connecting layer and a flexible anti-fouling layer which are sequentially formed on the surface of a base material. Wherein the substrate layer comprises adhesive resin, a positively charged polymer, a filler and a diluent; the corrosion barrier layer comprises flexible polymer resin, a negatively charged polymer and a two-dimensional nanosheet; the connecting layer comprises adhesive resin, a positively charged polymer, a filler and a connecting agent; the flexible anti-fouling layer comprises flexible polymer resin and a temperature-responsive polymer microcapsule encapsulated with an anti-fouling agent. The anti-corrosion, anti-fouling and anti-drag composite coating disclosed by the invention is high in binding force with a base material and also has anti-corrosion, anti-fouling and anti-drag properties; meanwhile, the preparation method provided by the invention has the advantages of wide application range, large-area coating and the like.

The invention discloses a preparation method of a layer-by-layer casting ultrathin asymmetric bipolar membrane, and belongs to the technical field of membrane separation. The invention aims to solve the problems that the total thickness of the traditional bipolar membrane is small, the water decomposition rate is low, and the conversion efficiency of different salts is obviously different. The asymmetric bipolar membrane is prepared by using a layer-by-layer casting method, and the thickness of the anion exchange layer and the cation exchange layer of the membrane is regulated, so that ion leakage is avoided, and the product purity is remarkably improved; the anion-cation exchange layer is prepared from a polymer with charge, and the adhesion capacity of the membrane is greatly improved by virtue of electrostatic attraction through the characteristic of opposite charge of the anion-cation exchange layer, so that the membrane is prevented from swelling in water. According to the invention, the anion and cation exchange membranes are adhered together through electrostatic adsorption force by virtue of the characteristic of opposite charges, the adhesion strength of the membrane is enhanced by virtue of the chemical compatibility of SPPSU and QPPO, the membrane has good mechanical property, and the service time and frequency of the membrane are improved.

The invention discloses a functionalized nano magnetic iron-based material as well as a preparation method and application thereof. The functionalized nano magnetic iron-based material comprises a magnetic Fe3O4 core, a SiO2 isolating layer, a polydopamine electron transfer strengthening layer and a positively charged polymer three-dimensional microspace conducting layer, the magnetic Fe3O4 core, the SiO2 isolating layer, the polydopamine electron transfer strengthening layer and the positively charged polymer three-dimensional microspace conducting layer are sequentially arranged from inside to outside. According to the invention, rapid recovery of materials is realized through design of magnetic components (sedimentation time lt; 5 min) and cyclic utilization (more than or equal to 10 times); the dispersibility of the material and the affinity of microorganisms are improved through surface functionalization design; and the starting period is shortened by more than 50% through an electron transfer process strengthening and directional microorganism enrichment synergistic interaction mechanism.

A method for treating a pathogen is described, comprising the steps of: (1) spraying a formulation onto a substrate, the formulation comprising: a charged polymer comprising charged monomers, counterions to the charged monomers; and, an adhesion promoter; (2) drying the formulation to yield a film comprising a critical load of adhesion in a range of 10 to 600 μN; (3) contacting the pathogen with the film; and (4) inactivating, with the film, at least fifty percent of the pathogen within thirty minutes of the step of contacting, where the adhesion promoter is optionally an antipathogen, such as a polydiallyldimethylammonium salt.

The invention discloses a gamma-glutamyl transpeptidase catalytic hydrolysis induced charge upset polymer, which contains a gamma-glutamyl transpeptidase response element part and a fluorescent probe corresponding fragment part, the invention also discloses a preparation method of the polymer for turning charge by catalytic hydrolysis of gamma-glutamyltranspeptidase and an application method of the polymer in the field of tumor imaging. According to the present invention, the gamma-glutamyltranspeptidase catalytic hydrolysis electric charge overturning polymer is adopted as the response type tumor imaging probe, such that the electric charge can be converted from the negative or neutral state to the positive state so as to achieve the rapid uptake of the positively charged polymer by the tumor cells so as to achieve the rapid spraying imaging, and the probe response after the uptake is adopted so as to achieve the rapid spraying imaging; the imaging effect of the probe on the tumor is greatly improved, and the probe has important significance in solid tumor imaging for assisting a doctor in surgical resection.

The invention discloses a two-dimensional heterogeneous self-assembled film and a preparation method thereof. The preparation method comprises the following steps: successfully synthesizing Fe3O4-COOH nanoparticles which are uniform in morphology and stable in size and have carboxyl modified surfaces by adopting an improved solvothermal method; then, the surface of the Fe3O4-COOH is modified with a layer of positively charged polymer BPEI through the electrostatic adsorption effect, and Fe3O4 (at) BPEI is formed; the preparation method comprises the following steps: preparing Fe3O4 (at) BPEI (at) Au, further uniformly adsorbing (12nm) gold nanoparticles on the surface of the Fe3O4 (at) BPEI (at) Au through electrostatic adsorption, finally forming a stable gold shell structure, constructing Fe3O4 (at) BPEI (at) Au with a magnetic core gold shell structure, modifying sulfydryl polystyrene (SH-PS) on the surface of the Fe3O4 (at) BPEI (at) Au, successfully preparing a two-dimensional heterogeneous self-assembled film by taking the Fe3O4 (at) BPEI (at) Au as a construction unit, and constructing the two-dimensional heterogeneous self-assembled film by taking the Fe3O4 (at) BPEI (at) Au as the construction unit. The two-dimensional heterogeneous self-assembled thin film shows good SERS enhancement performance and uniformity, and shows SERS signal sensitization capacity under the action of an external magnetic field.

The present disclosure provides analyte sensors comprising a sensing layer disposed upon a surface of a first working electrode, wherein the sensing layer comprises an NAD(P)-dependent enzyme and a supply of NAD(P); and a multilayered membrane that overcoats at least a part of the sensing layer and is permeable to an analyte, wherein the membrane comprises at least one layer of negatively charged polymer. The present disclosure also provides methods of using such analyte sensors for detecting one or more analytes preset in a biological sample and methods of manufacturing the analyte sensors.

The present invention discloses a super-slippery anti-fouling and drag-reducing composite coating with photothermal responsiveness, its preparation method and applications. The super-slippery anti-fouling and drag-reducing composite coating includes: a base layer, a homogeneous heat-absorbing layer, a porous heat-absorbing layer and a thermoresponsive super-slippery layer formed in sequence on the surface of a substrate; wherein, the base layer includes a positively charged polymer, an adhesive and a filler; the homogeneous heat-absorbing layer includes a hydrophobic resin, a negatively charged polymer and light-absorbing particles; the porous heat-absorbing layer includes a hydrophobic resin and light-absorbing particles, and the porous heat-absorbing layer has a porous structure; the thermoresponsive super-slippery layer includes paraffin and temperature-responsive polymer microcapsules encapsulating an anti-fouling agent. The super-slippery anti-fouling and drag-reducing composite coating with photothermal responsiveness provided by the present invention has a strong bonding force with the substrate, and also has the functions of storing a thermoresponsive phase change material, anti-fouling property and super-slippery property; at the same time, the preparation method provided by the present invention has the advantages of wide application range and large-area coating.

The invention discloses a charged hollow fiber loose nanofiltration membrane as well as a preparation method and application thereof. The hollow fiber nanofiltration membrane comprises a supporting layer and a charged separation layer, and the charged separation layer is attached to the inner surface of the hollow fiber supporting layer and is co-extruded and molded by adopting a double-layer spinneret plate; the charge separation layer comprises a charge polymer and a matrix polymer, and a positively charged polymer or a negatively charged polymer is selected according to an entrapment dye; the negatively charged separation layer further comprises hydroxylated polyether sulfone; the charged hollow fiber loose nanofiltration membrane is prepared by preparing an inner-layer membrane casting solution and an outer-layer membrane casting solution, carrying out co-extrusion molding through a double-layer spinneret plate, carrying out phase inversion membrane formation and then carrying out post-treatment. During application, corresponding charged nanofiltration membranes can be selected according to the electrical properties of dyes in sewage, efficient selective interception of different charged dyes is achieved, meanwhile, high transmittance is achieved for inorganic salt, the technological process of a one-step continuous forming process is simplified, the production efficiency is high, the method can be compatible with an existing hollow fiber membrane production line, and industrialization is easy to achieve.

Compositions including fusion proteins, viruses, and a synthetic charged polymer are provided. The composition includes a fusion protein reagent, one or more viral particles, and synthetic charged polymer, where the fusion protein reagent includes an affinity domain and a polypeptide with phase behavior, and where a molar ratio of the synthetic charged polymer to the fusion protein reagent is 400: 1 to 4: 1. The compositions may be used to control viral transduction. The compositions may be used to improve viral transduction. Methods of using the compositions to control of viral transduction and improve viral transduction are described.

Charged polymeric webs, such as electret webs, include a thermoplastic resin and a charge-enhancing additive. The additives are substituted heterocyclic thiolate salts. The heterocyclic thiolate salt has 2 nitrogen groups and a third group that may be an NH, N—NH2, O, or S group. The substituent group is an aromatic or heterocyclic aromatic group. The electret webs may be a non-woven fibrous web or a film. The electret webs are suitable for use as filter media.

The present disclosure provides analyte sensors comprising a sensing layer disposed upon a surface of a first working electrode, wherein the sensing layer comprises an NAD(P)-dependent enzyme and a supply of NAD(P); and a multilayered membrane that overcoats at least a part of the sensing layer and is permeable to an analyte, wherein the membrane comprises at least one layer of negatively charged polymer. The present disclosure also provides methods of using such analyte sensors for detecting one or more analytes preset in a biological sample and methods of manufacturing the analyte sensors.

The invention discloses a modified non-woven fabric, a filter element containing the modified non-woven fabric, a preparation method of the filter element and a water purifier. The modified non-woven fabric is characterized in that a modified layer is arranged on the non-woven fabric, and the modified layer is formed by first molecular chains and second molecular chains which are alternated; the first molecular chain comprises a structure formed by combining an amine monomer, a cross-linking agent and a charged polymer through chemical bonds; the second molecular chain comprises a structure formed by combining an amine monomer, a cross-linking agent and an uncharged polymer through chemical bonds; the ratio of the molecular weight of the charged polymer to the molecular weight of the non-charged polymer is 1: (1-1.5). The modified non-woven fabric can continuously and efficiently remove heavy metal, retain mineral substances and inhibit bacterial breeding, when the modified non-woven fabric is used in a filter element, the size of the filter element cannot be too large, the water flux of the filter element cannot be affected, on the contrary, structural parts of a filter element combination part can be reduced, and the cost of the filter element is reduced.

A multi-layer (multi-lamellar) coated nanoparticle is provided wherein the nanoparticle comprises a first coat comprising a positively charged polymer or a positively charged lipd bilayer and a second coat comprising an anionic bilayer and optionally one or more distinct cargo molecules, one or more distinct targeting moieties, or any combination thereof, as well as methods of making and using the nanoparticle.

Hollow glass microspheres (HGMS) with a controlled nanotopographical surface structure (NSHGMS) demonstrate improved isolation and recovery of cells and other biological particles such as bacteria from biological fluid. Such functionalized HGMS are formed by exposing a plurality of hollow glass microspheres to a layer by layer deposition cycle of charged polymeric nanofilms to form a plurality of coated hollow glass microspheres and functionally binding a plurality of biotinylated antibodies to the plurality of coated hollow glass microspheres. Application of these HGMS in related biological particle isolation methods does not require specialized lab equipment or an external power source, and thus, can be used for separation of targeted cells from blood or other fluid in a resource-limited environment.

The present invention discloses an anti-corrosion, anti-fouling and drag-reducing composite coating, a preparation method thereof and an application. The anti-corrosion, anti-fouling and drag-reducing composite coating comprises a base layer, a corrosion barrier layer, a connection layer and a flexible anti-fouling layer which are sequentially formed on the surface of a substrate; wherein, the base layer comprises an adhesive resin, a positively charged polymer, a filler and a diluent; the corrosion barrier layer comprises a flexible polymer resin, a negatively charged polymer and two-dimensional nanosheets; the connection layer comprises an adhesive resin, a positively charged polymer, a filler and a connecting agent; the flexible anti-fouling layer comprises a flexible polymer resin and temperature-responsive polymer microcapsules encapsulating an anti-fouling agent. The anti-corrosion, anti-fouling and drag-reducing composite coating in the present invention has a strong bonding force with the substrate and also has anti-corrosion, anti-fouling and drag-reducing properties; meanwhile, the preparation method provided by the present invention has the advantages of wide application range, large-area coating, etc.

The invention discloses a soybean protein-phospholipid biomimetic membrane as well as a preparation method and application thereof. The biomimetic membrane is formed by three raw materials of soybean protein, soybean lecithin and a charged polymer through electrostatic interaction and a physical blending method. The soybean 11s protein solution, the lipidosome dispersion liquid and the charged polymer solution are mixed to obtain the mosaic structure biomimetic membrane which is formed by combining various chemical bond crosslinking and electrostatic interaction, and the process conditions are simple, efficient, convenient and environmentally friendly. The biomimetic membrane provided by the invention has a mosaic structure and the characteristics of the raw materials, so that the biomimetic membrane has high ion passing rate, strong ion selection capability, excellent monovalent cation and divalent cation separation capability and certain biodegradability. When the biomimetic membrane is applied to ion separation, the separation capacity of ions with different valence states can be effectively improved, the separation effect of sodium ions and magnesium ions is optimal, and the separation factor is as high as 21.28 and is 54.6 times that of a biomimetic membrane without charges.

The present invention discloses a moisturizing composition and its preparation method and application. In terms of weight percentage, the moisturizing composition of the present invention includes the following components: 5% to 40% other alcohol moisturizers, 0.1% to 5% panthenol, 0.1% to 8% grease, 0.01% to 2% emulsifier, 0.001% to 0.05% polyquaternium-61, 0.1% to 1% other cationic conditioning agents, and the remainder is water. The moisturizing composition of the present invention can form a kind of outer layer positively charged polymer inclusion body that wraps grease, panthenol, etc., which can be combined with the negative charge of the skin during the cleaning process, so that some water-soluble moisturizers are not easily washed away by water during the flushing process, thereby adhering to the skin surface, providing a sense of not being tight and moisturizing after cleaning. The moisturizing composition of the present invention can be widely used in cosmetics to play a role in moisturizing, and is particularly applied to wash-off cosmetics.

The present invention relates to the technical field of mixed matrix membranes, and in particular to a crown ether-loaded UiO-66-NH2 mixed matrix membrane and its preparation method and application. The preparation method comprises: adding glacial acetic acid to a zirconium tetrachloride solution to obtain solution one; adding a crown ether to a 2,5-diaminoterephthalic acid solution to obtain solution two; mixing solution one and solution two and performing a hydrothermal reaction to obtain crown ether-loaded UiO-66-NH2; dispersing a positively charged polymer and crown ether-loaded UiO-66-NH2 in an organic solvent, mixing and forming a liquid film, and obtaining a crown ether-loaded UiO-66-NH2 mixed matrix membrane. The crown ether-loaded UiO-66-NH2 mixed matrix membrane of the present invention has good ion recognition ability, overcomes the defect of low selectivity of traditional polymer membranes; and overcomes the shortcomings of the existing chemical reaction grafting method, such as complex reaction process and high raw material cost, through in-situ coating technology.

A polymeric delivery system delivers a biologic to cells. In some embodiments, the polymeric delivery system includes polyplexes. Each polyplex includes at least one charged polymer and at least one biologic. The at least one charged polymer includes a polyester copolymer of a polyol and a polycarboxylic acid modified with at least one charged moiety having an opposite charge from a net charge of the at least one biologic. In other embodiments, the polymeric delivery system includes self-assembled particles including a block copolymer and a biologic associated with the block copolymer. The block copolymer includes a first block of a polyester copolymer of a polyol and a polycarboxylic acid and a second block of a second monomer or a second polymer.

The present invention discloses a Pomosomes hollow shell structure and a preparation method thereof. The preparation method comprises the following steps: (1) dissolving a positively charged polymer in an oil phase, and dispersing a polyoxometalate and an inorganic salt in an aqueous phase, wherein the polyoxometalate can form an assembly with the positively charged polymer through electrostatic interaction; the inorganic salt is used to reduce the electrostatic repulsion between polyoxometalates; (2) mixing the oil phase and the aqueous phase and then emulsifying, and standing to obtain an emulsion containing a nanoshell structure. The present invention prepares a stable shell structure by using small-sized nanoparticles as raw materials.

The present invention provides methods for characterizing the composition of polymers. Common to these methods, the subunits of a charged polymer strand are moved by the force of electrophoresis across closely spaced electrodes so as to produce tunneling currents modulated by their passage and indicative of their chemical structure. Comparisons of the electronic signals thus obtained to those of known standards that have undergone similar electrophoresis are made so as to determine the composition of the polymer and the linear sequence of its subunits.The invention described here may be used for: the detection and identification of biological agents that may be pathogenic; the sequencing of small linear RNAs that may be present in cells and those that have been linearized by the methods described herein; and the sequencing of linear genomic DNA, mRNAs, linear non-coding RNAs, and polypeptides.

The utility model relates to a kind of packaging structure of fast-charging polymer lithium ion battery, comprising: battery main body, the upper end of which is equipped with tab;Protection plate, is located in the upper end of the battery main body, the lower end surface of the tab is electrically connected after being bent;Plastic package part, is covered in the outside of the protection plate and tab;And connecting piece, with the upper end surface of the protection plate fixed connection, the connecting piece is bent and extends to the side of the battery main body after extending outwards and passing through the plastic package part, and is connected with the side of the battery main body.The utility model can connect the upper end surface of protection plate with the side of battery main body, form support, guide and disperse the stress on the tab of existing plastic package structure to the side of more stable battery main body, to enhance the overall stability and reliability of plastic package structure.

A polymeric delivery system delivers a biologic to cells. In some embodiments, the polymeric delivery system includes polyplexes. Each polyplex includes at least one charged polymer and at least one biologic. The at least one charged polymer includes a polyester copolymer of a polyol and a polycarboxylic acid modified with at least one charged moiety having an opposite charge from a net charge of the at least one biologic. In other embodiments, the polymeric delivery system includes self-assembled particles including a block copolymer and a biologic associated with the block copolymer. The block copolymer includes a first block of a polyester copolymer of a polyol and a polycarboxylic acid and a second block of a second monomer or a second polymer.

The present invention belongs to the technical field of analytical chemistry, and specifically relates to a mercaptonicotinic acid and gold nanoparticle modified graphene oxide material and its preparation method and application. The present invention obtains a mercaptonicotinic acid and gold nanoparticle modified graphene oxide material with higher selectivity for glycoprotein enrichment by improving the hydrophilicity, ionic interaction force and recognition ability of peptides of the material. The present invention uses graphene oxide as the initial material, and the surface of graphene oxide carries a large number of negatively charged oxygen-containing functional groups (epoxy groups and hydroxyl groups, etc.), so that it is easy to be modified by positively charged polymers through electrostatic interactions, and then the gold nanoparticles are modified by copolymerization, and the mercaptonicotinic acid is modified by gold-sulfur bond reaction. The prepared mercaptonicotinic acid and gold nanoparticle modified graphene oxide material has higher selectivity for glycoprotein enrichment and better hydrophilicity.

In the present invention, positively charged cerium hydroxide particles without undergoing surface charge treatment are subjected to ultrasonic agitation, so that a negatively charged polymer or monomer and the cerium hydroxide particles form a coordination bond, thereby forming a first surface coating layer and reversing the surface charge into a negative charge; and in a second coating step, a weakly positively charged polymer is added, so that by means of charge attraction, a polymeric ion pair is formed, thereby achieving a second charge reversal to a positive charge. Disclosed in the present invention is a method for multiple surface coatings of cerium hydroxide particles. The coated cerium hydroxide particles do not change the intrinsic electrical properties thereof, and can greatly reduce defects caused by mechanical forces during polishing, such as particle adhesion, thereby improving the product yield.