65results about How to "With controlled release" patented technology

The invention discloses a crease resistance and moisture retention liposome. The crease resistance and moisture retention liposome comprises, by mass, 1-3% of phosphatide, 0.5-1.5% of cholesterol, 0.05-0.15% of an antioxidant, 0.5-1.5% of Tween-80, 2-6% of a cryoprotectant, 84-94% of a phosphate buffering solution with the pH value of 6.5-7, 0.4-1.5% of an aqueous solution of superoxide dismutase, 0.4-1.5% of an aqueous solution of hyaluronic acid and 0.4-1.5% of an aqueous solution of ceramide, and the sum of the mass percentages of above components is 100%. The invention discloses a preparation method of the crease resistance and moisture retention liposome. The method comprises the following steps: preparing a blank liposome, wrapping active components by the blank liposome, and carrying out freeze-thawing and freeze-drying to prepare the crease resistance and moisture retention liposome. The crease resistance and moisture retention liposome can be added to cosmetics in order to prepare cosmetics with crease resistance and moisture retention efficacies.

The invention provides a core-shell type pre-charged chemotherapy medicine embolization microsphere and a preparation method thereof. The method comprises the following steps of using water/oil/water(W/O/W) complex emulsion type or oil/water/oil (O/W/O) complex emulsion type emulsified micro liquid drips as templates; coating tiny liquid drips containing medicine into outer layer liquid drips; high molecular polymers in the inner and outer layer liquid drips are converted through measures such as physical measures and chemical measures to form an inner layer core and an outer layer shell. Theformed core-shell structure medicine microsphere is formed by polymers of two-layer structures; the inner core contains medicine; the outer shell is favorable for maintaining the activity of the inner core medicine; the stable medicine release is realized; the sudden release is prevented; the safety is enhanced. The medicine carried microsphere prepared by the method has the advantages that the particle diameter range is 10 to 1000 micrometers; the sphere degree is good; the particle diameter is uniform; (the dimension deviation is 5 percent); the medicine encapsulation rate is high; the structure/carried medicine is controllable; meanwhile, the preparation method of the pre-charged chemotherapy medicine embolization microsphere can provide a novel idea for the clinic application study ofthe transcatheter arterial embolization.

The invention belongs to the field of fertilizer production and particularly relates to a soil conditioning organic fertilizer for preventing plant diseases and a preparation method thereof.The organic fertilizer is prepared from, by weight, 25-30 parts of zeolite, 35-45 parts of animal manure, 5-8 parts of plant ash, 7-10 parts of urea, 3-5 parts of humic acid, 1-3 parts of bacillus subtilis prepration, 8-10 parts of chitin powder, 8-10 parts of alginate and 1-2 parts of trace elements.The organic fertilizer is wide in raw material source, low in cost and capable of effectively preventing plant diseases and insect pests, reducing soil pollution, making soil matrix conditioning easier, fully releasing organic nutrients and making plants fully absorb various nutrients, can increase the survival rate of plants and make branches and leaves of the plants luxuriant, can improve disease resistance and pest resistance of the plants, and makes the yield of the plants higher.

The invention provides a paclobutrazol micro-capsule suspension preparation provided with sustained-release function, which includes the following components according to 100 parts by weight: 10 to 30 parts of film-forming materials, 5 to 40 parts of paclobutrazol, 5 to 10 parts of emulsifying agent and the rest parts of water. The potency of the suspension preparation is more moderate, the potency releases slower and lasts long, thus ensuring the adjustment of steady growth of plants and having the sustained-release function. The invention also provides a preparation method of the paclobutrazol micro-capsule suspension preparation.

The invention discloses a preparation method for microecologics for laying hen feeds and application of the microecologics. The microecologics is prepared by uniformly mixing living microcapsules bacterium powder with selenium carrageenan, zinc methionine and auxiliary materials through a spray drying technology, wherein living microcapsules bacterium powder is obtained by uniformly mixing lactobacillus plantarum and bacillus subtilis strains with an aqueous solution containing pectin, tween-80, glycerinum, mannitol, trehalose and sodium bicarbonate after the lactobacillus plantarum and the bacillus subtilis strains are subjected to enrichment culture. The microecologics can be stored under a normal-temperature condition and is high in enteric solubility and biological adhesive. On the basis of normal daily ration, the laying hens are also fed with the microecologics, so that the anti-oxidization capability of organ bodies of laying hens can be improved; therefore, the damage degree of fallopian tubes of the laying hens in the later period of laying is reduced, excessive release of inflammatory factors in tissues can be suppressed, and the injury caused by inflammatory reaction can be alleviated; the activity and the completeness of organ tissues and cells can be guaranteed, the organ health is retained, and the productivity is improved.

The invention discloses a nano antibacterial agent and a preparation method thereof and relates to an antibacterial agent and a preparation method thereof. The invention aims to solve the problems that the conventional nanometer material modified antibiotics applied to the antibacterial field have poor biocompatibility and do not have targeting property and the utilization rate of the antibioticsis low. The nano antibacterial agent is prepared by performing surface modification on a synergetic system of MOF and antibiotics with sodium hyaluronate, wherein the synergetic system of the MOF andantibiotics with sodium hyaluronate is formed by encapsulating the antibiotics in a zeolite imidazate framework structure material ZIF-8. The method comprises the following steps: 1, preparing the synergetic system of the MOF and antibiotics; 2, performing surface modification on the prepared synergetic system of the MOF and antibiotics with a sodium hyaluronate solution, and performing vacuum drying, thereby obtaining the nano antibacterial agent. According to the preparation method disclosed by the invention, the nano antibacterial agent can be obtained.

Provided is a method for feeding myxocyprinus asiaticus by the adoption of nano controlled-release feed. A cultivating pool is a circular or square cement pool, the area of the cultivating pool is 12-20m<2>, and the depth of the cultivating pool is 0.7-1m; the method needs to meet the requirements for good water circulation and pollution discharge functions; water is transparent and clear and does not contain harmful heavy metal ions, water of 70-100cm depth flows into the pool for the first time, dbdmh of 0.3mg/L is used for disinfecting the water, and healthy individuals without disease are chosen to be placed in the cultivating pool. By the adoption of the method, scientific and refined feeding is carried out, the yield-increasing effect is obvious and survival rate is high within a short time, and the method is suitable for industrialized and large-scale development.

The invention discloses a method for breeding finless eel by nano feeds. The method comprises the following steps: selecting a pond which is in east and west directions, has a length-to-width ratio of 3 to 2, an area of 2000-10000m<2>, a pond ridge height of 1.8-2.0m and a stable water level of 1.4-1.5m, and is provided with perfect water drainage facilities as a breeding pond; disinfecting the pond in 10-15 days before finless eel fries are put into the pond, draining off water in the pond, checking whether holes are formed, cleaning the pond by unslaked lime, and feeding the finless eel fries with multifunctional microorganism feeds. Through comparison, and by adding a compound microorganism fertilizer, the finless eel can be promoted to grow quickly, the EPA (eicosapentaenoic acid) content can be increased, the finless eel diseases are reduced, the fatality rate is reduced, meanwhile beneficial microorganisms in a water body are added, and the final quality is improved.

The invention discloses a cultivation method capable of reducing stichopus japonicus disease and pest injuries with corrosion inhibition nanometer materials. The method includes the following steps that a stichopus japonicus cultivation pool and an adhesion base are constructed; according to the requirement for habits of the stichopus japonicus biology, the pool suitable for growth of stichopus japonicus is built up by combining with real conditions and stichopus japonicus offspring seeds are put; normally, large seeds with the density of more than 600 per kilogram are put according to the density of 10 per m<2> to 20 per m<2>, the larger the specifications are, the less the put amount per unit area is; a formula of the cast feed comprises, by weight, 20-25 parts of animal proteolysis article dry powder, 15-20 parts of meat and bone meal, 20-22 parts of soybean meal, 4-6 parts of honeysuckle, 2-3 parts of medicated leaven, 3-5 parts of angelica sinensis, 2-3 parts of soya bean lecithin, 1-2 parts of alginate-derived oligosaccharide, 1-2 parts of vitamin C, 1-2 parts of spiral seaweed, 2-3 parts of hunmulus lupulus, 3-5 parts of tea saponin, 2-3 parts of common cnidium fruit, 3-4 parts of fructus ulmi and 1-2 parts of cortex pseudolaricis. The stichopus japonicus offspring seeds are managed. In winter, the depth of water in the pool is increased, changes of dissolved oxygen and a base material must be paid attention to and sea grass is prevented and controlled; in spring, when the temperature of the water in the pool goes up, firstly, the water goes rich, the transparency of the water is reduced and cultivation of the sea grass is controlled.

The invention discloses a microbial nano sustained-release fish feed and a preparation method thereof. The microbial fish guano comprises the following components in parts by weight: 2-4 parts of bacillus subtilis powder, 1-4 parts of ferment bacteria, 0.5-0.9 parts of solid photosynthetic bacteria, 0.8-1.2 parts of bdellovibrio bacteriovorus, 0.2-0.6 parts of vitamin additive, 10-16 parts of mineral additive, 0.2-0.4 parts of chelating agent, 60-80 parts of water hyacinth and the like. The microbial fertilizer added with the microbial fish guano disclosed by the invention can be used for promoting quick growth of fish and improving the quality and mass of the fish; moreover, beneficial microorganisms in water are increased, and the fish disease can be effectively prevented, so that the farming method adopting the microbial fish guano is economical and effective.

The invention discloses a special controlled-release fertilizer for lotus roots and a preparation method thereof. The preparation method comprises the following steps of preparing a fertilizer core by urea, potassium chloride, calcium phosphate, a trace element fertilizer, an inhibitor and a dispersant; performing inner coating treatment on the fertilizer core by an inner coating film agent which is prepared from polylactic acid, polyethylene glycol and ethyl alcohol; performing outer coating treatment on the fertilizer core by an outer coating film agent which is prepared from polyacrylate, ethylene propylene diene monomer, modified starch, acetone and water, so as to obtain the special controlled-release fertilizer for the lotus roots. Compared with the prior art, the special controlled-release fertilizer has the advantages that the nutrient elements in the fertilizer are rich, the utilization rate of a nitrogen fertilizer is high, the controlled-release property is good, and the nutrient requirement of the lotus root in each growth period is met; the outer coating can be recycled, so that the environment-friendly effect is realized; the inner coating can be completely degraded, so that the danger to surrounding environment is avoided.

The invention discloses a wormwood pig feed which comprises the following raw materials in parts by weight: 6-8 parts of wormwood, 1-5 parts of honeysuckle leaves, 0.1-0.3 part of RADIX ASTRAGALI, 5-9parts of fine powder of mineral substances, 0.5-1.5 parts of composite vitamins, 10-18 parts of wheat bran, 15-20 parts of rice chaff, 1-2 parts of a plant extract, 4-10 parts of starch, 0.1-0.2 partof a composite enzyme preparation, 7-9 parts of rapeseed bran, 2-4 parts of fish flour, 5-7 parts of carrots, 5-10 parts of corn, 1-3 parts of a composite acidification agent and 0.1-0.2 part of an antioxidant. By adopting the pig feed disclosed by the invention, not only are nutrition requirements of pigs to growth met, but also pig feed digestion intestinal tracts can be improved, digestion andabsorption of nutrition substances can be improved, the disease infection rate can be reduced, and particularly African swine fever can be reduced; and meanwhile, the preparation method disclosed bythe invention is low in material cost, easy in raw material obtaining, clear and simple in process, high in practical value and good in application prospect.

The invention belongs to the field of Chinese pharmaceutics, and discloses a psoralen-quercetin composite solid lipid nanoparticle preparation and a preparation method thereof. The preparation comprises psoralen, quercetin, solid lipid, a fat soluble emulsifier, a water soluble emulsifier, an organic solvent, water for injection and ice water, wherein the weight ratio of the five materials is (1-4): (1-5): (60-200): (100-300): (200-800). By means of the prepared preparation, the solubility of psoralen and quercetin is improved, the physical and chemical stability and bioavailability of medicine are improved, the anti-tumor and reverse activity of multidrug resistance of the medicine are enhanced, and meanwhile, the preparation has sustained release, controlled release and targeting functions, and can improve the treatment effect of the medicine remarkably. Besides, the preparation process is simple, industrial production is facilitated, and innovativeness and practicability are achieved.

The invention discloses a method for breeding bluefin tuna by nano slow-release carrier feeds. The method comprises the following steps: putting adult bluefin tuna into a pond with fresh water, the depth of 2.0-2.5m and the pH value of 7.0-8.5 in the morning from the middle of March to the middle of April under the condition that the water temperature is 15-20 DEG C, and breeding 2250-3000 silver carp fries being 10-12cm per hm<2> and 375 spotted silver carp fries per hm<2> in the pond at the same time, wherein a net box is made of polyethylene net pieces. By adding a compound microorganism fertilizer, the bluefin tuna can be promoted to grow quickly, the EPA (eicosapentaenoic acid) content can be increased, the diseases of the bluefin tuna are reduced, the fatality rate is reduced, beneficial microorganisms in a water body are added, and the final quality is improved.

The invention discloses a method for breeding artificial aeguidens rivulatus fries by nano feeds. The method comprises the following steps: selecting a breeding facility, namely a square pond with the characteristics of flat bottom, less sludge, convenience in irrigation and drainage and average water depth of 0.8m; disinfecting the pond by 10mg/L of trichloroisocyanuric acid in 10 days before aeguidens rivulatus is put into the pond; keeping clear water and the pH value to be 7.8, wherein aeguidens rivulatus fries are hatched out by fertilized ova after 2-3 days and can freely move for finding foods in another 5-6 days; feeding the aeguidens rivulatus fries with fairy shrimps or small water fleas for four times each day in the beginning; after half a month, feeding the aeguidens rivulatus fries with blood worms (cladocerans); after a month, feeding the aeguidens rivulatus fries with artificial compound feeds, optimally selecting and using feeds with high protein content such as fresh fish meat, shrimp meat and snail meat, also selecting and using compound feeds, and generally feeding the aeguidens rivulatus fries with animal feeds for improving the nutrition and promoting the gonad development of parent fishes in a breeding season.

The invention discloses a method for preparing a slow release feed for carps by adopting nano materials. A composite microorganism fish fertilizer specially used for the carps comprises the following components in parts by weight: 2-4 parts of nitrogen-fixing bacteria, 1-3 parts of phosphate solubilizing bacteria, 3-5 parts of enzyme bacteria, 50-60 parts of fish meal, 75-80 parts of bean cakes, 20-30 parts of bran, 70-80 parts of rice bran, 10-14 parts of brown sugar, 8-10 parts of yeast powder, 12-15 parts of edible salt and the like. The composite microorganism fertilizer disclosed by the invention can promote rapid growth of fish and also improve the grade and the quality of the fish, so that diseases of the fish can be reduced; meanwhile, beneficial microorganisms in water can be increased, and the growth of phycophyta in a fishpond is alleviated.

The invention provides a phosphate fertilizer controllably released through a pH-sensitive material. The phosphate fertilizer is characterized by being prepared by coating a water-soluble phosphate fertilizer with the pH-sensitive material, wherein the pH-sensitive material is prepared by crosslinking wheat gluten and zeolite under the action of a crosslinking agent; after a crop is lack of phosphorus, the pH value of the periphery of the root system is reduced because organic acid secreted by the root system of the crop is increased, and the wheat gluten embedded in pores of the zeolite is pored through soluble inflation and hydrolysis under the condition of low pH value, so that a controlled release effect is achieved; and at the moment, water-soluble phosphorus cannot be fixed by soil due to the existence of organic acid, so that the efficient absorption of the crop on phosphorus is increased to the maximum extent, and the fixed and lost phosphorus is reduced. By using the phosphate fertilizer controllably released through the pH-sensitive material, the problems that the absorption and utilization rates of crops on phosphorus are low and phosphorus is easily fixed and lost because phosphorus in the existing controlled-release phosphate fertilizer cannot be controllably released according to the growth demands of the crops are solved.

The invention discloses a preparation method of a special controlled-release fertilizer for sorghum. After a fertilizer core is prepared by urea, monopotassium phosphate, calcium phosphate, a trace element fertilizer, an inhibitor and a dispersing agent, the fertilizer core is subjected to coating processing by using a coating agent prepared from polylactic acid, polyurethane, modified starch, acetylacetone cobalt, ethyl alcohol and water, so as to obtain the special controlled-release fertilizer for the sorghum. According to the preparation method, compared with the prior art, the prepared controlled-release fertilizer is sufficient in nutrient element and high in utilization rate of a nitrogen fertilizer, can be decomposed under the light, has controlled-release performance, and can meet nutrition requirements of the sorghum in each growth period; meanwhile, a coating is environmental-friendly, is completely degradable, and cannot damage the surrounding environment.

The invention belongs to the field of spice preparation, and particularly relates to a preparation method of a rose essence embedded spice and a method for controllably releasing rose essence by carbon dioxide. The method comprises the steps: 1) mixing rose essential oil, N-alkyl imidazole and water to prepare a mixed solution; and 2) mixing the mixed solution with carbon dioxide to form an aggregate solution system. According to the rose essence embedding spice and the preparation method thereof, N-alkyl imidazole reacts with carbon dioxide in a water system to generate N-alkyl imidazole bicarbonate with surface activity, and the N-alkyl imidazole bicarbonate can embed rose essence in an aggregate form and form a stable aggregate solution system, so that the rose essence embedded spice which is stable in a normal state is constructed. By utilizing the sensitivity of the N-alkyl imidazole bicarbonate to CO2 in a water system, the N-alkyl imidazole bicarbonate can be reversely convertedinto the N-alkyl imidazole, and the N-alkyl imidazole has no surface activity, so that the controlled release of an embedding system is realized.

The invention discloses a preparation method of special controlled-release fertilizer for Chinese water chestnuts. After fertilizer core is prepared from urea, potassium chloride, calcium phosphate, microelement fertilizer, an inhibitor and a dispersant, the fertilizer core is subjected to inner coating treatment with an inner coating agent consisting of polylactic acid, polyethylene glycol and ethyl alcohol and then subjected to outer coating treatment with an outer coating agent consisting of polyacrylate, EPDM (ethylene-propylene-diene monomer) rubber, modified starch, acetone and water, and the special controlled-release fertilizer for the Chinese water chestnuts is obtained. Compared with the prior art, the obtained controlled-release fertilizer has sufficient nutrient elements and high nitrogen fertilizer utilization rate, has controlled-release performance and can meet the nutrition requirement of the Chinese water chestnuts in each growth period; meanwhile, outer coats can be recycled and are environment-friendly, inner coats can be completely degraded, and the surroundings are not damaged.