Analyte sensor

an analyte sensor and sensor technology, applied in the field of analyte sensors, can solve the problems of inability to accurately sensing and reporting back analyte values continuously, unable to provide short-term or less-than-accurate blood glucose sensing, and inability to accurately detect and monitor blood glucos

Inactive Publication Date: 2011-02-03
DEXCOM
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  • Abstract
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AI Technical Summary

Benefits of technology

[0085]In an embodiment of the sixth aspect, at least one of processing the first signal or processing the second signal comprises evaluating an accuracy of the first calibrated signal and an accuracy of the second calibrated signal.
[0086]In an embodiment of the sixth aspect

Problems solved by technology

Many conventional implantable glucose sensors suffer from complications within the body and provide only short-term or less-than-accurate sensing of blood glucose.
Additionally, many conventional transcutaneous and intravasc

Method used

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Embodiment Construction

[0137]In order to facilitate an understanding of the embodiments described herein, a number of terms are defined below.

[0138]The term “analyte,” as used herein, is a broad term, and is to be given its ordinary and customary meaning to a person of ordinary skill in the art (and is not to be limited to a special or customized meaning), and refers without limitation to a substance or chemical constituent in a biological sample (e.g., bodily fluids, including, blood, serum, plasma, interstitial fluid, cerebral spinal fluid, lymph fluid, ocular fluid, saliva, oral fluid, urine, excretions or exudates). Analytes can include naturally occurring substances, artificial substances, metabolites, or reaction products. In some embodiments, the analyte for measurement by the sensing elements, devices, and methods is albumin, alkaline phosphatase, alanine transaminase, aspartate aminotransferase, bilirubin, blood urea nitrogen, calcium, CO2, chloride, creatinine, glucose, gamma-glutamyl transpepti...

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Abstract

Devices and methods are provided for continuous measurement of an analyte concentration. The device can include a sensor having a plurality of sensor elements, each having at least one characteristic that is different from other sensor(s) of the device. In some embodiments, the plurality of sensor elements are each tuned to measure a different range of analyte concentration, thereby providing the device with the capability of achieving a substantially consistent level of measurement accuracy across a physiologically relevant range. In other embodiments, the device includes a plurality of sensor elements each tuned to measure during different time periods after insertion or implantation, thereby providing the sensor with the capability to continuously and accurately measure analyte concentrations across a wide range of time periods. For example, a sensor system 180 is provided having a first working electrode 150 comprising a first sensor element 102 and a second working electrode 160 comprising a second sensor element 104, and a reference electrode 108 for providing a reference value for measuring the working electrode potential of the sensor elements 102, 104.

Description

CROSS-REFERENCE TO RELATED APPLICATION[0001]This application claims the benefit of priority under 35 U.S.C. §119(e) of U.S. Provisional Application No. 61 / 222,716 filed Jul. 2, 2009, U.S. Provisional Application No. 61 / 222,815 filed Jul. 2, 2009, and U.S. Provisional Application No. 61 / 222,751 filed Jul. 2, 2009, the disclosures of which are hereby expressly incorporated by reference in their entirety and are hereby expressly made a portion of this application.FIELD OF THE INVENTION[0002]The embodiments described herein relate generally to devices, systems, and methods for measuring an analyte in a host.BACKGROUND OF THE INVENTION[0003]Electrochemical sensors are useful in chemistry and medicine to determine the presence or concentration of a biological analyte. Such sensors are useful, for example, to monitor glucose in diabetic patients and lactate during critical care events. A variety of intravascular, transcutaneous and implantable sensors have been developed for continuously d...

Claims

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Application Information

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IPC IPC(8): G01N27/26G01N33/50G01N27/416
CPCA61B5/14532A61B5/14865A61B2560/0223A61B2562/0209A61B5/1473A61B2562/125B05C3/10A61B5/1451A61B5/14517A61B2562/043B05C5/0241B05C3/125B05C3/02B05D1/18B05D3/06B23K26/0823B23K26/362B29C2791/009C23C2/00A61B5/14503A61B5/14546
Inventor SIMPSON, PETER C.BOOCK, ROBERTKAMATH, APURV ULLASWIGHTLIN, MATTHEWESTES, MICHAEL J.
Owner DEXCOM
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