This invention belongs to the field of
nuclear medicine imaging technology, specifically relating to a PET myocardial
blood flow quantitative optimization method, including the following steps: determining the shortest effective
acquisition time: for specific types of research subjects and pathophysiological states, the injection time is determined through experimental analysis. 18 After F-Flurpiridaz, the shortest effective
acquisition time required to achieve stable myocardial
blood flow (MBF) quantification is achieved; an optimized
acquisition protocol is implemented; image reconstruction and MBF quantification are performed based on the optimized
acquisition time; results are verified and reported. This invention significantly improves scanning and quantification efficiency: by shortening the effective acquisition time by 2-7 minutes, the occupancy time of the
PET scanner can be substantially reduced while ensuring
data quality, increasing equipment turnover and enabling more subjects to be examined within the same time period.