Systems, methods, and devices provide data correction for
positron emission
tomography (PET) examinations using an external, supplemental
radioactive source. The supplemental
radioactive source is formed of a uniformly distributed
radionuclide. The uniformly distributed
radionuclide is positioned in a support structure which is positioned into an inner bore of a
PET scanner and secured in place by a friction fit, or directly integrated into the PET
system. A transmission source
control system moves the one or more 2024 / 059537 transmission sources into the support structure for performing the PET examination (e.g., using a hydraulic
system). The transmission source
control system also retracts the one or more transmission sources back into a source storage device upon completing the PET examination. Various data correction algorithms use the first PET
signal data, originating from a radiotracer injected in the patient, and second PET
signal data, originating from the uniformly distributed
radionuclide.