121results about How to "Efficient insertion" patented technology

Disclosed is a system for debugging a computer program. A user indicates a specified breakpoint type, such as a program statement, variable reference, command, etc. The program, including program statements, is then compiled. During compilation, the compiler locates statements in the program corresponding to the breakpoint types and generates a function call into the program at instances in the program of statements corresponding to the user specified breakpoint types. During a debugging phase, a debugger may execute an executable version of the program, including the function calls. Upon processing the function calls, the debugger may stop execution of the program and pass control to the user to perform debugging operations.

A feedthrough terminal assembly for an active implantable medical device includes a conductive ferrule conductively coupled to a housing of the medical device, a feedthrough capacitor conductively coupled to the ferrule, an inductor closely associated with the capacitor in non-conductive relation, and a conductive terminal pin extending through the capacitor and the inductor. The terminal pin extends through the inductor in non-conductive relation and is conductively coupled to active electrode plates of the capacitor. In one preferred form, the terminal pin is wound about the inductor. Additionally, the inductor may be maintained in close association with the capacitor without forming a direct physical attachment therebetween.

A method of generating a product recipe for execution by a batch process in an automated manufacturing environment, such the product recipe is associated with a plurality of actions, a set of transitions, and a set of parameters, and such that the plurality of actions define a plurality of logical levels including a phase level at which the batch process interacts with equipment, includes receiving a procedure definition specifying the plurality of actions, receiving a transaction definition specifying the set of transitions so that each one in the set of transitions is associated with two or more of the plurality of actions, and receiving the set of parameters. Receiving the set of parameters includes receiving at least one dynamic input parameter that resolves to a value without obtaining the value from the recipe or an operator prompt associated at the phase level of the recipe.

An endoscope-like image taking method includes providing at least one peculiar index, which can be discriminated from other portions on an MR image, at the tip of a catheter, previously inserting a metal guide wire for guiding the catheter into a body cavity of a patient inserting the catheter into the body cavity along the guide wire, executing an MR imaging sequence of a plurality of sliced images intersecting the guide wire, reconstructing three-dimensional image data based upon the nuclear magnetic resonance signals, which are received by the guide wire, and determining the tip position and the inserting direction of the catheter by detecting the peculiar index provided at the tip of the catheter based upon the three-dimensional image data, and reconstructing the center projected image using the three-dimensional image data and setting the tip position and the inserting direction of the catheter as a view point and a line-of-sight direction and displaying the center projected image on a display means.

A system for enabling the insertion and removal of an embolic protection device, for capturing and retaining embolic debris which may be created during the performance of a therapeutic interventional procedure in a stenosed or occluded region of a blood vessel. The system, in an embodiment thereof, enables the device to be snap-fitted so as to engage the distal end of a guide wire, to be pre-formed for expansion thereof so as to seal off the inner surface of a blood vessel, to inhibit the forming of a gap therein, for inhibiting embolic material from passing therethrough, and to be foreshortened to enable insertion thereof through confined spaces. The system, in another embodiment thereof, enables expandable material to be formed into an expandable configuration of an embolic protection device for capturing embolic material, which is capable of sealing off the inner surface of the blood vessel.

Various devices and methods are provided for dilating tissue. In one embodiment, a trocar cannula is provided and includes an elongate tubular member defining an inner lumen extending therethrough and configured to receive a surgical instrument therethrough. The tubular member is configured to radially expand to increase an inner diameter of the inner lumen and thereby dilate tissue. In one embodiment, the tubular member has an expansion element incorporated therein and the expansion element is configured to maintain the tubular member in a radially expanded position when no instrument is disposed within the inner lumen.

Disclosed herein is a genetically-modified cell comprising in its genome a modified human T cell receptor alpha constant region gene, wherein the cell has reduced cell-surface expression of the endogenous T cell receptor. The present disclosure further relates to methods for producing such a genetically-modified cell, and to methods of using such a cell for treating a disease in a subject.

The method and apparatus for drilling holes and optionally inserting fasteners of the present invention provide for efficiently drilling holes through a multiple-layer structure because the layers are securely held together during the drilling by an electromagnet and a clamp, each on opposite sides of the structure. The electromagnet and clamp hold the layers together so tightly that burrs do not form within the holes and debris does not accumulate between the layers and, therefore the layers do not have to be disassembled after drilling. In addition, the apparatus and method of the present invention provide for initially drilling the hole with a countersink and for inserting a fastener into the hole, through the electromagnet, immediately after drilling the hole, such that the hole does not have to be revisited after reassembly and drying of the sealant in order to drill a countersink and / or insert a fastener.

The invention discloses a method for site-specific integration of a large DNA fragment in a mammalian cell through CRISPR / Cas9. The method comprises the following steps: (1) constructing a CRISPR / Cas9 targeting system of a target CCR5 gene, wherein the targeting system comprises a Cas9 / sgRNA expression vector and a targeting donor, the targeting donor comprises a promotor, a fluorescence labelling gene and a design, and the design of the targeting donor comprises a gRNA target sequence at the middle part and shares a homologous sequence with a target gene; (2) enabling the CRISPR / Cas9 targeting system to cotransfer the mammalian cell, separating the cell stably expressing fluorescence after cotransfecting, and conducting single cell clone culture; (3) detecting the site-specific integration efficiency through single cell clone PCR, and acquiring the efficient site-specific site-detected integration mammalian cell. The method can realize the site-specific site-detected integration of the large DNA fragment more than 6 kb in the mammalian cell.

This invention introduces a new concept called virtual construct intervals (VCI), where each predicate interval is decomposed into one or more of these construct intervals. These VCIs strictly cover the predicate interval. Namely, every attribute value covered by the predicate interval is also covered by at least one of the decomposed VCIs, and vice versa. Each construct interval has a unique ID or interval coordinate and a set of endpoints. A construct interval is considered activated when a predicate interval using it in its decomposition is added to the system. The predicate ID is then inserted into the ID lists associated with the decomposed VCIs. To facilitate fast search, a bitmap vector is used to indicate the activation of VCIs that cover an event value. The challenge is to find an appropriate set of construct intervals to make predicate decomposition simple and, more importantly, to build efficient bitmap indexes. Because each construct interval covers only a small range of attribute values, the invention also uses bitmap clipping to cut unnecessary bitmap storage. To facilitate bitmap clipping, the invention introduce the covering segment concept. Bit positions outside a covering segment are pruned.

An endoscope-like image taking method of the present invention includes a preparation step of providing at least one peculiar index, which can be discriminated from other portions on an MR image, at the tip of a catheter, a first step (S1) of previously inserting a metal guide wire for guiding the catheter into a body cavity of a patient into which the catheter is inserted, a second step (S2) of inserting the catheter into the body cavity along the guide wire, a third step (S3) of executing an MR imaging sequence of a plurality of sliced images intersecting the guide wire, a fourth step (S4) of reconstructing three-dimensional image data based upon the nuclear magnetic resonance signals, which are generated from the patient when the sequence is executed and are received by the guide wire, and determining the tip position and the inserting direction of the catheter by detecting the peculiar index provided at the tip of the catheter based upon the three-dimensional image data, and a fifth step (S5) of reconstructing the center projected image using the three-dimensional image data and setting the tip position and the inserting direction of the catheter as a view point and a line-of-sight direction and displaying the center projected image on a display means, thereby an endoscope-like image, which is observed from the catheter in the body cavity of the patient, is taken and displayed in real time or semi-real time so that the insertion of the catheter is supported.

A method and system for segmenting wires in the design stage of a integrated circuit to allow for the efficient insertion of an optimum quantity of buffers. The method begins by locating wires in the integrated circuit which interconnect transistors and then determining the characteristics of the transistor and the characteristics of the interconnecting wires. Next, the method computes a first upper limit for an optimum quantity of buffers utilizing total capacitive load wire and transistor characteristics, then the method computes a second upper limit for an optimum quantity of buffers assuming buffer insertion has decoupled the capacitive load. Finally, the method segments the wires by inserting nodes utilizing the greater of the first computation or the second computation. A determined upper limit on buffer quantity allows wires to be segmented such that the number of candidate buffer insertion topologies is manageable. Therefore, an optimum number of buffers can be efficiently inserted by buffer insertion method which utilize the segmented wires.

Apparatus and method offloads processing from a networking processor operating in a storage environment. Three main functions are offloaded: semaphore processing, frame order processing, and timer processing. Offloading of semaphore processing enables ordered access to semaphores. Offloading of frame order processing enables the network processor to quickly transmit an incoming frame if the incoming frame is the next one in the frame order. Offloading of timer processing enables background checking of the timer list.

The invention provides a column-based storage and research method and equipment based on a hard disk and the internal storage. A data sheet structure on data source is created in the internal storage through creating metainformation of the data sheet corresponding to the data source, and a column-based data block is generated on the current data according to the metainformation and is stored into the hard disk; the internal storage can be used more effectively, the following query data performance in the hard disk reaching the similar performance with the query data in the internal storage is realized, and the strong data analysis ability based on high-speed query efficiency can be further supported in following; moreover, when the column is an index column, the following data query efficiency can be improved by establishing a reverse index for each index column and storing the index column to the document at corresponding position in a solid state disk with the adoption of RadixTree structure.

A PC card slot device for an ExpressCard affords a smooth insertion of the ExpressCard into a slot for the PC card slot device, without the height of the slot being increased. A lower chassis ceiling wall defines the lower face side of a card storage space, and also includes a slot side edge that is formed of a rear-side inclined line portion and a slot-side inclined line portion. The rear-side inclined line portion and the slot-side inclined line portion are respectively inclined at angles α1 and α2, relative to a reference cross section. To insert the ExpressCard into the slot of the card storage space, the right corner of the right upper level lower face portion of the card is inserted into the card storage space and the front end of the right stepped portion of the card is guided along the inclined line portions.

A power of a square matrix is determined in a time approximately proportional to the upper integer of the base-2 logarithm of the order of the matrix. A preferred embodiment uses two types of look-up tables and two multipliers for a matrix of 15×15, and is applied to a pseudorandom noise (PN) sequence phase correlation or state jumping circuit. An exact state of a PN code can be determined or calculated from applying an appropriate offset value into a control circuit. The control circuit can produce a PN sequence state from the offset value and typically does so within one system clock period regardless of the amount of the offset. Once the exact state is determined, it is loaded into a state generator or linear sequence shift register (LSSR) for generating a subsequent stream of bits or symbols of the PN code. The PN generator system may include state computing logic, a maximum length PN generator, a zero insertion circuit and a zero insertion skipping circuit.

The invention provides a method and a device for data storage so as to solve the problem of low memory utilization rate. The method includes that if requested data can be stored in a paging allocation memory block, an idle memory block is selected to store the requested data; and if data size is larger than the paging allocation memory block, a part of data of the requested data is stored in the idle memory block, the other part of surplus data is stored in one or a plurality of available memory blocks, and all the memory blocks storing the requested data are connected through indicating needles. The available memory blocks are scattered memory blocks, the size of the scattered memory blocks is not necessarily to be the same as that of the paging allocation memory block, and accordingly memory waste can be avoided to the greatest extent, and memory utilization rate can be improved to the maximum limit.

Disclosed herein is a genetically-modified cell comprising in its genome a modified human T cell receptor alpha constant region gene, wherein the cell has reduced cell-surface expression of the endogenous T cell receptor. The present disclosure further relates to methods for producing such a genetically-modified cell, and to methods of using such a cell for treating a disease in a subject.

The invention concerns a piezo insert and a piezo packer for implant surgical operation with a piezoelectric device. The piezo insert according to the invention consists of a piezo insert body one end of which is inserted in and fixed to a hand piece of the piezoelectric main device; an insert pole extending from the other end of the piezo insert body; and an insert tip formed at the end of the insert pole. The piezo packer consists of a piezo packer body one end of which is inserted in and fixed to a hand piece of a piezoelectric main device; a packer pole extending from the other end of the piezo packer body and a packer tip formed at the end of the packer pole. With the piezo insert and the piezo packer according to the invention, forming and expanding a hole in a vertical direction in a residual ridge at a portion for implant placement is facilitated when applying bone grafting in a maxillary sinus, and damages can be avoided in a maxillary sinus membrane, in order to effectively insert graft materials through the formed hole in the residual ridge for bone grafting.

Disclosed herein are recombinant meganucleases engineered to recognize and cleave a recognition sequence present in the human T cell receptor alpha constant region gene. The present disclosure further relates to the use of such recombinant meganucleases in methods for producing genetically-modified eukaryotic cells.

An adhesive composition, an adhesive, and an adhesive sheet are suitable for optical components such as a polarized sheet and have excellent stress relaxation property. The adhesive composition comprises monomer units which form a polymer, a (methyl) acrylate polymer (A) which has carboxyl-contained monomers and has weight-average molecular weight of being 500,000 to 3 million, and a reactive polyrotaxane compound (B) containing cyclic oligosaccharide having polymerized double bonds.

A flame-retardant, characterized in that it comprises a layered titanic acid in the form of a nano sheet which is formed by a method comprising treating a layered titanic acid salt with an acid or warm water and then reacting the resultant mixture with an organic basic compound, or carrying out the step of treating a layered titanic acid salt with an acid or warm water and the step of reacting with an organic basic compound, in one pot, to thereby swell or separate the layers; and a flame-retardant resin composition, characterized in that it comprises 100 parts by weight of a resin and 0.5 to 50 parts by weight of the above layered titanic acid in the form of a nano sheet.

A website construction support system includes: an input section that enables input of a goal page among webpages; an access log acquisition section that acquires access log information; a calculation section that calculates an access frequency and an arrival frequency based on the access log information; a page judgment section that makes a judgment so that a webpage with the access frequency larger than a boundary condition is a customer-collecting page and a webpage with the arrival frequency larger than a boundary condition is a conversion page; a link decision section that generates, based on the judgment result, notice link including a customer-collecting page as a link source and a conversion page as a link target; and a page generation section that inserts the generated notice link in the customer-collecting page as the link source.