124 results about "Therapeutic Technique" patented technology

Disclosed are compositions, systems and methods for treating a subject's body, body part, tissue, body fluid cells, pathogens, or other undesirable matter involving the administration of a targeted thermotherapy that comprises a bioprobe (energy susceptive materials that are attached to a target-specific ligand). Such targeted therapy methods can be combined with at least one other therapy technique. Other therapies include hyperthermia, direct antibody therapy, radiation, chemo- or pharmaceutical therapy, photodynamic therapy, surgical or interventional therapy, bone marrow or stem cell transplantation, and medical imaging, such as MRI, PET, SPECT, and bioimpedance. The disclosed therapies may be useful in the treatment of a variety of indications, including but not limited to, cancer of any type, such as bone marrow, lung, vascular, neuro, colon, ovarian, breast and prostate cancer, epitheleoid sarcomas, AIDS, adverse angiogenesis, restenosis, amyloidosis, tuberculosis, cardiovascular plaque, vascular plaque, obesity, malaria, and illnesses due to viruses, such as HIV.

Embodiments of the invention disclosed herein generally include methods and / or devices for increasing blood flow, controlling the vasodilatation of a patient's vascular structure, regulating the temperature of a portion of a mammal, and for improving various interventional procedures and / or therapeutic techniques. The device may also include one or more access ports, or apertures, that allow access to portions of the mammal's extremity to allow interventional type medical devices, therapeutic devices, surgical support equipment or patient monitoring devices to have access to the extremity on which a body element is disposed. The device may also be configured to allow other supporting components, which may include IV or other catheters, a means of accessing to a portion of the extremity positioned inside the temperature regulating device. In one configuration the device comprises flexible materials that are adapted to conform to the surface of the extremity disposed in the device when a vacuum pressure is applied to an internal region of the device.

A method for direct therapeutic treatment of myocardial tissue in a localized region of a heart having a pathological condition. The method includes identifying a target region of the myocardium and applying material directly and substantially only to at least a portion of the myocardial tissue of the target region through transseptal delivery. The material applied results in a physically modification the mechanical properties, including stiffness, of said tissue. Various devices and modes of practicing the method are disclosed for stiffening, restraining and constraining myocardial tissue for the treatment of conditions including myocardial infarction or mitral valve regurgitation. The novel treatment may be combined with prior art diagnostic and therapeutic techniques employing transseptal delivery methods.

A user directed interactive method and system for implementing customized therapy routines. The method and system obtains relevant information from a user via an interactive questionnaire and via digital therapeutic techniques to evaluate the user's pain and provide a customized treatment regimen. The user then implements the custom treatment regimen in order to return their body to proper alignment thereby bringing about a state of muscular and internal balance to the individual naturally. In this manner, the method and system of the present invention replicates the process of in-clinic and video therapy programs while delivering customized therapy sessions and long-term therapy programs based on the user's individual needs via an electronic medium that is completely automated without the need for professional intervention, evaluation, or correspondence of any kind.

The present invention provides a coating that emits magnetic resonance signals and a method for coating medical devices therewith. The coating includes a paramagnetic metal ion-containing polymer complex that facilitates diagnostic and therapeutic techniques by readily visualizing medical devices coated with the complex. The present invention also provides methods by which pre-existing polymers and medical devices may be made MR-imageable. The invention also provides methods of improving MR-imageability of polymers and medical devices by encapsulating the polymers and medical devices with hydrogels.

A patient support system to be used in conjunction with a standard linear accelerator, and other sources, is described that allows access of the treatment beam to the breast from up to 360 degrees. This support system places the patient in a prone position with the breast going through an aperture. The prone position increases the separation of the breast from the chest wall and other critical organs and reduces motion of the target tissue due to breathing. This invention offers up to 360 degree radiation beam access to the breast. This helps in skin sparing, better dose conformity, and allows one to use modern treatment techniques such as IMRT and IGRT. It also includes a provision for an imaging system. This invention can also be used with CT and MR imaging modalities.

Brachytherapy radioisotope carrier systems and methodology for providing real-time customized brachytherapy treatment to subjects with tumors difficult to control using conventional radiation therapy techniques. The invention generally relates to devices, methods and kits for providing customized radionuclide treatments, to help cure, slow progression or regrowth, or ameliorate the symptoms associated with tumors.

Described herein are compositions and methods for the treatment of cancer, and particularly brain cancer (e.g., glioma) in a mammal. In various embodiments of the invention, a combined therapeutic approach including TK with systemic ganciclovir administration and Flt3L are used in connection with gene therapeutic techniques or direct peptide injection for the aforementioned indications. Kits useful in practicing the inventive method are also disclosed, as are animal models useful for studying brain cancer.

Brachytherapy radioisotope carrier systems and methodology for providing real-time customized brachytherapy treatment to subjects with tumors difficult to control using conventional radiation therapy techniques. The invention generally relates to devices, methods and kits for providing customized radionuclide treatments, to help cure, slow progression or regrowth, or ameliorate the symptoms associated with tumors.

Brachytherapy radioisotope carrier systems and methodology for providing real-time customized brachytherapy treatment to subjects with tumors difficult to control using conventional radiation therapy techniques. The invention generally relates to devices, methods and kits for providing customized radionuclide treatments, to help cure, slow progression or regrowth, or ameliorate the symptoms associated with tumors.

A robotic system and a method are provided. The robotic system includes a continuum robot, an actuation unit, and a flexible positioning shaft. The continuum robot is configured to perform minimally invasive diagnostic, surgical or therapeutic techniques, and includes at least one continuum segment including a plurality of backbones. The continuum segment carries at least one diagnostic, surgical or therapeutic instrument in a flexible instrumentation housing that has a plurality of instrumentation channels. The actuation unit is configured to actuate the continuum robot by providing linear actuation to each of the plurality of backbones, and includes force sensors for measuring actuation forces. The flexible positioning shaft is configured to direct a position and orientation of the continuum robot and to couple the actuation unit to the continuum robot.

Methods and compositions for modulating growth of a neuron with a Wnt, a Wnt-like substance, and / or a chemical compound affecting a Wnt signaling pathway are disclosed. Also disclosed are methods for identifying a substance that modulates growth of a neuron by obtaining a candidate substance and contacting the candidate substance with the neuron are disclosed and methods for modulating growth of a neuron in a subject using a Wnt, a Wnt-like substance, and / or a chemical compound affecting a Wnt signaling pathway. The Wnt, Wnt-like substance, and / or chemical compounds affecting a Wnt signaling pathway can be delivered to the subject using gene therapy techniques. Also disclosed are pharmaceutical compositions for modulating growth of a neuron in a mammal that include a Wnt or a Wnt-like substance. Methods and compositions for inhibiting growth of a neuron are also disclosed.

The present invention provides a coating that emits magnetic resonance signals and a method for coating medical devices therewith. The coating includes a paramagnetic metal ion-containing polymer complex that facilitates diagnostic and therapeutic techniques by readily visualizing medical devices coated with the complex.

An “I” shaped therapeutic neutral spine and exercise device for improving muscle balance and soft-tissue and dural / nerve mobility by encouraging and facilitating proper neutral position of the entire spine is disclosed. The device has three sections of different dimensions; a cervical, thoracic and lumbar section. Each section is placed at a specific area of the spine. Each section can be utilized independently or as a whole by health care providers while administering manual therapy techniques or by users themselves by self-administering stretches. Each section is filled with grain, bean, pea, shell or synthetic substance with optionally attachable tabs to allow the user to utilize each section independently or the device as a whole. The device comes in various sizes to accommodate various lengths of the spine. Methods of administering the therapeutic neutral spine and exercise device on users by health care professionals for enhancing neutral spinal position, improving muscle balance, soft tissue and nerve tissue tension are also disclosed.

A pulsation system and method includes a pulsation device that generates pulsation patterns and ancillary therapeutic techniques, such as music, images, and aromatherapy. A communication device operates the pulsation device. The communication device transmits signals to the pulsation device through cable or wireless connectivity. Pulsation patterns and ancillary therapeutic techniques store in communication device data storage portion. The stored pulsation patterns and ancillary therapeutic techniques can be retrieved by the communication device and used repetitively to generate prerecorded pulsation patterns. The pulsation system coordinates the pulsation signals in chronological pattern to provide different rhythms and intensities of pulsations. The pulsation system also coordinates the playback of audio and images into a chronological pattern, forming an audiovisual story. The remote signal includes a remote user's voice.

The invention relates to a laser and magnetoelectricity comprehensive therapy and a multi-functional therapeutic instrument. The laser and magnetoelectricity comprehensive therapy is a comprehensive physical energy therapy without injecting and taking medicines, that is, the comprehensive energy of laser, a magnetic field, and an electric field acts on a human body to generate photochemical effect, magnetic water effect and electric effect, activate cells for promoting microcirculation, activate blood vessels for improving the activity of erythrocytes, reducing the aggregation of blood platelets and promoting blood circulation with oxygen, purify blood for promoting the metabolism of the human body, and stimulate channels and acupuncture points to ensure that an autonomic nerve is balanced further to resist and remove the damage of free radicals on the human body. The laser and magnetoelectricity comprehensive therapy and the multi-functional therapeutic instrument are used for the treatment of common diseases and frequently encountered diseases, the prevention of subhealthy state, health care, cosmetology, weight losing and so on. The comprehensive therapy is integrated with laser and magnetoelectricity, and the light, the magnetism and the electricity are compatible with one another in principle, so the prior treatment range of the laser, the magnetic field, the electric field and so on, is covered; and the laser and the magnetoelectricity comprehensively act on the human body, and the treatment effects of the laser and the magnetoelectricity are the superposition of various single physical energy therapies due to the all-round three-dimensional treatment.

Methods, systems and computer program products for combining atrial defibrillation treatment techniques include techniques for reducing the discomfort associated with defibrillation and / or reducing the defibrillation threshold. Techniques include timing the defibrillation shock to reduce discomfort based on a sensed signal, giving the shock relatively early during atrial fibrillation, therapeutic drugs, administering more than one shock in succession, pacing the heart before, after, or during the defibrillation shock or shocks, and placing the shock electrodes in locations that may reduce discomfort.

The invention discloses a lower lumbar segment unbalance rehabilitation therapeutic machine which comprises an upper working area supporting plate frame and a lower working area supporting plate frame, wherein the upper working area supporting plate frame is longitudinally arranged on a rack and is used for a region above a human hip joint; the lower working area supporting plate frame is arranged on the rack and is used for a region below the human hip joint; a headrest shoulder chest back backrest, a lumbar segment supporting device and a pelvis fixing device are longitudinally arranged on the upper working area supporting plate frame; a lower limb movement supporting device and an ankle elastic vibrating traction apparatus are longitudinally arranged on the lower working area supporting plate frame. The lower lumbar segment unbalance rehabilitation therapeutic machine has the advantages that the lower lumbar segment unbalance rehabilitation therapeutic machine is obtained based on traditional Chinese and western medicine orthopaedic clinical diagnosis and treatment practices; work doing treatment is carried out by taking the pelvis of a human body as a center point; the lower lumbar segment unbalance rehabilitation therapeutic machine takes in numerous application rehabilitation therapeutic technique modes such as pulling pressing, thrusting, jacking pressing, side-pulling side-rotation, traction vibration, stepped vibrating resetting, ankle traction trunk tendon loosening and the like of auxiliary application; the rehabilitation therapeutic equipment adopting a non-surgical treatment means is provided for patients who suffer from the lower lumbar segment unbalance disease.

The invention relates to the technical field of rehabilitation treatment, and provides a rehabilitation assistive system, a rehabilitation assistive method based on VR technology and a rehabilitationassistive device. The rehabilitation assistive method includes steps of performing early evaluation on a rehabilitation object before rehabilitation; performing virtual and reality multi-level VR experience on the rehabilitation object according to the early evaluation, collecting physiological data of the rehabilitation object according to the multi-level VR experience, and performing the later evaluation on the rehabilitation object when the multi-level VR experience is finished; generating a rehabilitation evaluation report according to the early evaluation, the multi-level VR experience, the physiological data and the later evaluation so as to interpret or promote to carry out rehabilitation assistance on the rehabilitation object. Through the method, the system can fully combine VR, physiological data and rehabilitation treatment technologies together and carry out organic comprehensive use; thus the rehabilitation assistance is more exact; by referring to actual condition of every patient, the rapid and effective rehabilitation treatment can be realized.

The invention discloses application of a PARP1 inhibitor in the preparation of a medicine for reversing drug resistance of tumor cells to amethopterin and belongs to the technical field of tumour biotherapy. It is found by the inventor through researches that as for malignant cells with MTX resistance and DHFR gene high-amplification, by specifically inhibiting the key protein RARP1 of A-NHEJ pathway, DHFR gene copy number can be reduce and DMs in cells can be decreased so as to reverse drug resistance of tumors and enhance efficiency of tumor therapy. Therefore, on the basis of the above researches, the invention brings forward the application of the PARP1 inhibitor in the preparation of a medicine for reversing the drug resistance of tumor cells to MTX by reducing DHFR gene copy number. The invention provides a new targeting therapeutic scheme for the MTX as the main therapeutic drug and for the biotherapy of malignant tumors which are easy to resist drugs and also provides a scientific basis for effectively fighting against MTX drug resistance. In addition, the invention is also of great positive significance for deeply understanding the nature of chemotherapy resistance and finding resistance target for individualized treatment.

The invention belongs to the field of radiotherapy technology application, and relates to a method for preventing collision between a therapy machine head and a therapy bed in the radiotherapy process. In the method, the point furthest from the equal center point in the therapy bed is used as a reference point by adopting a method of judging the position relation between a point and a circle in a standard equation of the circle, and whether the therapy bed collides with the therapy machine head is prejudged by judging the position relation between the reference point and the circle encircled by the rotating radii of the machine head. Using results show that the method is simple to implement and reliable in precision, facilitates clinical application, and can be integrated in the existing radiotherapy planning system, thereby greatly reducing the workload of technicians, reducing the radiation to the technicians, simultaneously shortening the therapy time and reducing the probability of position movement caused by intolerance of patients.

Provided is a therapeutic technique for treating baldness, using an umbilical cord blood-derived stem cell. Transplantation of a composition for treating baldness into a bald area of a patient can make great contributions to treatment for baldness, wherein the composition comprises stem cells isolated and cultured from umbilical cord blood in which 6 HLA (Human Leukocyte Antigen) are identical with a patient, or one or two HLA are not identical with the patient.

The invention relates to an electrical stimulation treatment instrument for masticatory muscles, which is used for rehabilitation of the masticatory muscles of patients with masticatory muscle atrophy. The electrical stimulation treatment instrument comprises a signal acquisition module, an electric signal processing modules, a control module, a pulse generation module and an electrical stimulation treatment module, and adopts a technology for treatment of the masticatory muscle atrophy through electrical stimulation based on electromyographic feedback, pulse transmission for the electrical stimulation is started by bio-electrical signals from the masticatory muscles, and the electrical stimulation mode is directly related to recovery of the patients, so that the atrophic masticatory muscles can be trained reasonably according to the corresponding extent of recovery and can be restored rapidly. In the electrical stimulation treatment of the masticatory muscle atrophy, the atrophic masticatory muscles are mainly stimulated through current pulses for contraction of the masticatory muscles, obvious treatment effects can be achieved, the instrument can be used conveniently, and the patients can be encouraged to actively participate in treatment.

The invention provides a scalp acupuncture therapeutic apparatus for infantile cerebral palsy. The scalp acupuncture therapeutic apparatus comprises a therapeutic cap which is arranged on the head of a patient and can be subjected to self-adaptive regulation according to the head size of the patient, a player, a five-element music sound wave converter of traditional Chinese medical science, which is electrically connected with the player, and a direct-current power supply which is electrically connected with the five-element music sound wave converter of traditional Chinese medical science, wherein first electrode raised heads which are in one-to-one correspondence to four-shen point regions on the top of head of a human body and second electrode raised heads which are in one-to-one correspondence to five-point regions of foreheads are arranged on the therapeutic cap, and are electrically connected with the five-element music sound wave converter of traditional Chinese medical science; and parts of the therapeutic cap, which are attached to ears of the human body are provided with telephone receivers connected with the player. Due to the adoption of the scheme, the scalp acupuncture therapeutic apparatus can be subjected to self-adaptive regulation according to the head size of the patient and can be positioned to acupuncture points of the head of the patient accurately, and an aim of treating infantile cerebral palsy effectively is fulfilled by the principle of transcranial direct current-five element sound wave stimulation of traditional Chinese medical science, a scalp-acupuncture therapeutic technology and a five-element music therapy of traditional Chinese medical science.

The invention relates to a HIFU cancer fusion system, which comprises at least one HIFU therapeutic-equipment and one open MRI system, wherein the magnetic material of MRI system is vertical to the ground; said therapeutic-equipment is between the magnetic materials. The invention combines MRI technique and HIFU technique, to mount HIFU therapeutic-equipment between magnetic materials easily. The invention has high safety, reliability and low cost.