The invention discloses a medicine for treating mental disease. Gentian, aloe, Chinese angelica, goldthread, golden cypress, scutellaria root, cape jasmine fruit, rheum officinale, costustoot, indigo naturalis, musk and chordiazepoxide are mixed uniformly, and crushed into 200-mesh fine powder, and the fine powder is filled into capsules to prepare a capsule preparation. The medicine has the effects of clearing heat and releasing toxin, cooling liver and arresting convulsion, relaxing bowel, and causing resuscitation and restoring consciousness, and is mainly used for treating mania, namely dementia praecox. The medicine has the quick and effective effect of antipsychotic western medicines, also achieves the curing effect of traditional Chinese medicines, does not need to be taken for a long time after the mental disease is cured, reduces harmful side effects on heart, liver, spleen, lung and kidney due to long-term administration of western medicines, and radically solves the problems of mental pressure of psychopaths and troubles for long-term administration of the antipsychotic western medicines. Through clinical curative effect observation, the total effective rate is 88.0 percent.