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32 results about "Decreased Concentration" patented technology

Impaired ability to sustain attention.

DECREASING GENE EXPRESSION IN A MAMMALIAN SUBJECT IN VIVO VIA AAV-MEDIATED RNAi EXPRESSION CASSETTE TRANSFER

Decreasing the expression of genes in a mammalian subject has multiple applications ranging from cancer therapy to anti-infective therapy or treatment of autosomal dominant genetic disorders. Yet, there is still a lack of efficient technologies to achieve that goal in mammalian subjects in vivo. The present invention relates to methods for decreasing gene expression by administering to a mammalian subject a recombinant adeno-associated viral vector in vivo with said vector comprising an RNA interference (RNAi) expression cassette whose RNA expression products directly or indirectly lead to a decrease in expression of the corresponding RNAi target gene. Upon successful transduction with the recombinant adeno-associated viral vector, the RNA expression products of the RNAi expression cassette will decrease the cellular concentration of the mRNA transcripts of the RNAi target gene, thus resulting in decreased concentration of the protein encoded by the RNAi target gene.
Owner:HILDINGER MARKUS +1

Subterranean Treatment Methods using Methanol Containing Foams

Methods using foamed fluids to perform subterranean formation treatments, the fluid containing methanol having a decreased concentration of gelling agent, while retaining excellent rheological properties in the foamed state, and processes for preparing foamed fluid for use in treating subterranean formations.
Owner:SCHLUMBERGER TECH CORP

Compound semiconductor epitaxial structure and method for fabricating the same

A method for fabricating a compound semiconductor epitaxial structure includes the following steps. Firstly, a first compound epitaxial layer is formed on a substrate. Then, a continuous epitaxial deposition process is performed to form a second compound epitaxial layer on the first compound epitaxial layer, so that the second compound epitaxial layer has a linearly-decreased concentration gradient of metal. Afterwards, a semiconductor material layer is formed on the second compound epitaxial layer.
Owner:UNITED MICROELECTRONICS CORP

Porous Hybrid Monolith Materials With Organic Groups Removed From the Surface

A material for chromatographic separations, processes for its preparation, and separation devices containing the chromatographic material. In particular, porous inorganic / organic hybrid monoliths are provided with a decreased concentration of surface organic groups, and have improved pH stability, improved chromatographic separation performance, and improved packed bed stability. These monoliths may be surface modified resulting in higher bonded phase surface concentrations and have enhanced stability at low pH.
Owner:WATERS TECH CORP

Method for sustaining Microorganism culture in Syngas fermentation process in decreased concentration or absence of various substrates

ActiveUS20100227377A1Preventing rapid lossDecreased absenceBacteriaUnicellular algaeMicroorganismAlcohol
The present invention relates to methods for sustaining microorganism culture in a syngas fermentation reactor in decreased concentration or absence of various substrates comprising: adding carbon dioxide and optionally alcohol; maintaining free acetic acid concentrations; and performing the above mentioned steps within specified time.
Owner:JUPENG BIO HK LTD

Medicinal product and method for treatment of conditions affecting neural stem cells or progenitor cells

InactiveUS20050032702A1Modulate proliferationModulate differentiationNervous disorderPeptide/protein ingredientsOligodendrocytePharmacy medicine
Use of a substance that upon administration will lead to increased concentrations of growth hormone, such as growth hormone, a functionally equivalent analogue thereof or a substance that will increase the release of endogenous growth hormone, for the production of a medicinal product for treatment of abnormal conditions affecting neural stem cells, progenitor cells and / or cells derived from neural stem cells or progenitor cells, especially conditions affecting the oligodendroglia, astroglia, and / or neuronal cells. In vitro and in vivo methods for inducing lineage determination, propagating and / or inducing or maintaining the genesis of neurons, oligodendrocytes, astroglial cells from progenitor cells, stem cells and / or cells derived from said cells by administrating to the cells a substance that increases the concentration of growth hormone. Also a method of reducing the genesis of oligodendrocytes, neurons, astroglial cells from progenitor cells or stem cells, wherein a pharmaceutically effective amount of a substance that will lead to a decreased concentration of growth hormone or a functionally equivalent analogue thereof is administered to said patient.
Owner:ERIKSSON PETER

Electronic device, manufacturing method of electronic device, and sputtering target

A film formation is performed using a target in which a material which is volatilized more easily than gallium when heated at 400° C. to 700° C., such as zinc, is added to gallium oxide by a sputtering method with high mass-productivity which can be applied to a large-area substrate, such as a DC sputtering method or a pulsed DC sputtering method. This film is heated at 400° C. to 700° C., whereby the added material is segregated in the vicinity of a surface of the film. Another portion of the film has a decreased concentration of the added material and a sufficiently high insulating property; therefore, it can be used for a gate insulator of a semiconductor device, or the like.
Owner:SEMICON ENERGY LAB CO LTD

Method for extracting carrageenan

The invention discloses a method for extracting carrageenan, which comprises the following steps: washing a raw material with water, performing combined alkali treatment on the raw material, wherein the concentration of alkali is decreased gradually, washing the raw material to enable the pH to be 7-8; carrying out composite enzyme treatment, removing heavy metals by using a metal chelating agent, boiling carrageenan, filtering coarsely, filtering finely, reducing temperature, gelling, dewatering, cutting into strips, drying, crushing and screening so as to obtain the carrageenan. According to the invention, a mixed solution of NaOH, KOH and LCI with gradually decreased concentration in three grades is adopted in an alkali treatment process, the loss of carrageenan is reduced effectively while the alkali treatment time is reduced; cellulase and protease combined treatment is adopted, and the yield of the carrageenan is improved while the high gel strength of the carrageenan is ensured; ethylene diamine tetraacetic acid and nopotassium phosphate are adopted for further treatment for the raw material, and the heavy metals in the raw materials are removed effectively. The gel strength of the carrageenan prepared by the method is greater than or equal to 2139.2 g / cm<2>, the extraction rate is greater than or equal to 23.9 percent, Pb is less than or equal to 2.5 mg / kg, As is less than or equal to 1.0 mg / kg, Hg is less than or equal to 0.5 mg / kg, and the Cd is less than or equal to 1.0 mg / kg.
Owner:GREENFRESH FUJIAN FOODSTRUFF

Method of treating a hydrocarbon stream comprising cyclopentadiene and one or more diolefins

A method of treating a hydrocarbon stream comprising cyclopentadiene (CPD) and one or more diolefins, the method comprising: providing a hydrocarbon stream comprising an initial CPD concentration, an initial target diolefin concentration, and an initial secondary diolefin concentration; subjecting the hydrocarbon stream to preseparation conditions effective to separate (a) a crude target diolefin feedstock having a decreased concentration of CPD and an increased target diolefin concentration, and (b) a CPD dimerization feedstock having a decreased target diolefin concentration and an increased CPD concentration that is 1.5 or more times the initial CPD concentration; subjecting the CPD dimerization feedstock to CPD dimerization conditions effective to produce a raw DCPD stream comprising 20 wt. % or more DCPD; and, separating a high purity DCPD product stream comprising 90 wt. % or more DCPD from the raw DCPD stream.
Owner:SHELL OIL CO

Methods, apparatuses and systems for processing fluid streams having multiple constituents

Methods, apparatuses and systems for processing fluid streams having multiple constituents are provided including embodiments utilizing ascending temperature separation processes as well as combined ascending and descending temperature separation processes. For example, in one embodiment, a mixed gas stream may be processed by flowing the stream through multiple heat exchangers, expanding the stream, and then separating the stream into a liquid portion and a vapor portion. The vapor portion, having an increased or decreased concentration of an identified constituent may then pass through the heat exchangers again in reverse order and collected. The liquid portion may then be subjected to further, sequential separation acts which each take place at increasing temperatures. In another embodiment, numerous, sequential separation acts take place in, for example, at decreasing temperatures and, subsequently, at increasing temperatures. Such a mixed fluid stream, for example, may include constituents such as hydrogen, carbon monoxide and methane.
Owner:BATTELLE ENERGY ALLIANCE LLC

System and method for treating infectious waste matter

A system and method is provided for producing a safely disposable end product from waste matter containing undesirable materials, such as infectious, biohazardous, hazardous, or radioactive elements. The method comprises the steps of providing a highly alkaline solvent, immersing the waste matter containing the undesirable materials within the highly alkaline solvent, and heating the solvent. The waste matter containing the undesirable materials is allowed to remain within the solvent until digested, thereby forming a solution void of any infectious or biohazardous elements and / or containing a decreased concentration of radioisotope.
Owner:DIGESTOR LLC

Method of fabricating a semiconductor device having a decreased concentration of phosphorus impurities in polysilicon

In a method for manufacturing a semiconductor device having a laminated gate electrode, a phosphorus-doped polysilicon is formed on a gate oxide film. A high-melting metal or a compound of a high-melting metal and silicon is formed on the polysilicon. Phosphorus is doped into the polysilicon so that a concentration of the phosphorus in the polysilicon at an interface between the polysilicon and the gate oxide film is 2×1020(1 / cm3) or less. Then, thermal oxidation is carried out in a wet-hydrogen atmosphere containing water vapor.
Owner:PS4 LUXCO SARL

NRF2 Deficiency Influences Susceptibility to Steroid Resistance via HDAC2 Reduction

InactiveUS20140080795A1BiocideHydroxy compound active ingredientsDiseaseHistone deacetylase 2
Methods for the treatment or prevention of diseases which are caused by the decreased concentrations of histone deacetylase 2 (HDAC2) in cells are described. The diseases which may be treated by the methods of the invention include chronic obstructive pulmonary disease (COPD) and asthma, including steroid resistant COPD and asthma. The invention provides methods for treating or preventing of diseases caused by the degradation of HDAC2 by providing to the subject in need of treatment or prevention a molecular compound capable of preventing the degradation of HDAC2. Such molecular compounds include Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) activators. Methods are further provided for the treatment and prevention of COPD and asthma by providing to a subject in need of such treatment and prevention a nucleic acid which causes expression of HDAC2 in lung cells and / or a nucleic acid which causes expression of Nrf2 in lung cells.
Owner:UNIVERSITY OF ROCHESTER

Ceramides and their use in diagnosing cvd

The present invention inter alia provides a method, and use thereof, of predicting CV complications such as AMI, ACS, stroke, and CV death by determining the concentrations of at least one ceramide of Group A and at least one ceramide of Group B in a biological sample and comparing those concentrations to a control. Finding a decreased concentration of at least one Group A ceramide and an increased concentration of at least one Group B ceramide indicates that the subject has an increased risk of developing one or more CV complications. Also provided area newly identified subset of ceramide molecules, labelled versions thereof, and kits and compositions comprising the same for use in predicting and / or diagnosing CV complications.
Owner:ZORA BIOSCIENCES OY

Semiconductor device and manufacturing method of the same

In J-FET, since the impurity concentration of a channel region is lower than that of a gate region and a back gate region, p type impurity form the gate region and the back gate region diffuses such that n type impurity from the channel region below a gate region has a decreased concentration, thus resulting in the problems of deterioration of the forward transfer admittance gm and increase of the voltage gain Gv, and increase of the noise voltage Vno, which are caused by the IDSS variation and increase of the resistant of the current path. An n type impurity region is continuously formed on the bottom portion of a channel region below a source region, a gate region and a drain region. The n type impurity region has an impurity concentration higher than the channel region and a back gate region, and is less influenced by the diffusion of p type impurities from the gate region and the back gate region. Moreover, by continuously forming the impurity region from a portion below the source region to a portion below the drain region, the resistance value of a current path in the impurity region is substantially uniformed. Therefore, the IDSS is stabilized, the forward transfer admittance gm and the voltage gain Gv are improved, and the noise voltage Vno is decreased. Furthermore, the IDSS variation within a single wafer is suppressed.
Owner:SANYO ELECTRIC CO LTD +1

Ethanol yield and reduction of biomass accumulation in the recombinant strain of Saccharomyces cerevisiae overexpressing atpase

A new approach for increase of ethanol yield during alcoholic fermentation via decrease of biomass accumulation by using ATP degrading enzymes is described. The part of the Saccharomyces cerevisiae SSB1 gene coding for cytosolic ATPase domain of ribosome associated chaperon cloned into expression cassette under control of the glycerol-3-phosphate dehydrogenase gene (GPD1) promoter was introduced into the S. cerevisiae BY4742 strain. The recombinant strains were tested for their ability to grow and produce ethanol during glucose anaerobic and aerobic cultivations. Strains overexpressing ATPase domain of SSB1 possessed decreased concentration of intracellular ATP. They accumulated elevated amounts of ethanol and were characterized by decreased biomass accumulation as compared to the wild-type strain under both anaerobic and aerobic conditions. Similarly, the apyrase gene apy from E. coli encoding ATP / ADP hydrolyzing phosphatase and ATPase domain of SSB1 gene of S. cerevisiae were co-expressed under the control of galactose-inducible GAL1 promoter. The recombinant S. cerevisiae strains revealed slight reduction of biomass accumulation, while specific ATPase activity, ethanol accumulation and yield during alcoholic galactose fermentation under semi anaerobic conditions were increased.
Owner:ARCHER DANIELS MIDLAND CO

Electronic device, manufacturing method of electronic device, and sputtering target

A film formation is performed using a target in which a material which is volatilized more easily than gallium when heated at 400° C. to 700° C., such as zinc, is added to gallium oxide by a sputtering method with high mass-productivity which can be applied to a large-area substrate, such as a DC sputtering method or a pulsed DC sputtering method. This film is heated at 400° C. to 700° C., whereby the added material is segregated in the vicinity of a surface of the film. Another portion of the film has a decreased concentration of the added material and a sufficiently high insulating property; therefore, it can be used for a gate insulator of a semiconductor device, or the like.
Owner:SEMICON ENERGY LAB CO LTD

Ethanol yield and reduction of biomass accumulation in the recombinant strain of saccharomyces cerevisiae overexpressing atpase

ActiveUS20120088290A1Increased ethanol productionDecreased ATP levelFungiBacteriaAtp degradationGlycerol
A new approach for increase of ethanol yield during alcoholic fermentation via decrease of biomass accumulation by using ATP degrading enzymes is described. The part of the Saccharomyces cerevisiae SSB1 gene coding for cytosolic ATPase domain of ribosome associated chaperon cloned into expression cassette under control of the glycerol-3-phosphate dehydrogenase gene (GPD1) promoter was introduced into the S. cerevisiae BY4742 strain. The recombinant strains were tested for their ability to grow and produce ethanol during glucose anaerobic and aerobic cultivations. Strains overexpressing ATPase domain of SSB1 possessed decreased concentration of intracellular ATP. They accumulated elevated amounts of ethanol and were characterized by decreased biomass accumulation as compared to the wild-type strain under both anaerobic and aerobic conditions. Similarly, the apyrase gene apy from E. coH encoding ATP / ADP hydrolyzing phosphatase and ATPase domain of SSB1 gene of S. cerevisiae were co-expressed under the control of galactose-inducible GAL1 promoter. The recombinant S. cerevisiae strains revealed slight reduction of biomass accumulation, while specific ATPase activity, ethanol accumulation and yield during alcoholic galactose fermentation under semi anaerobic conditions were increased.
Owner:ARCHER DANIELS MIDLAND CO

Agent for preventing or improving decline in brain function

ActiveUS10905705B2Preventing and improving decline in brain functionMemory behavior can be synergistically and effectively improvedOrganic active ingredientsNervous disorderCitrullineExercise performance
An objection of the present invention is to provide an agent for preventing or improving decline in brain function such as decreased perception ability, decreased memory learning ability, decreased thinking ability, decreased concentration, decreased attention, decreased judgment ability, depression, and decreased exercise performance caused thereby. According to the present invention, an agent for protecting brain neuronal cells, comprising citrulline or a salt thereof and citicoline or a salt thereof as active ingredients as well as an agent for preventing or improving decline in brain function, comprising citrulline or a salt thereof and citicoline or a salt thereof as active ingredients is provided.
Owner:KYOWA HAKKO BIO CO LTD

Agent for preventing or improving decline in brain function

ActiveUS20150306125A1Preventing and improving decline in brain functionPreventing and improving in brain functionBiocideNervous disorderExercise performanceDecreased Concentration
An objection of the present invention is to provide an agent for preventing or improving decline in brain function such as decreased perception ability, decreased memory learning ability, decreased thinking ability, decreased concentration, decreased attention, decreased judgment ability, depression, and decreased exercise performance caused thereby. According to the present invention, an agent for protecting brain neuronal cells, comprising citrulline or a salt thereof and citicoline or a salt thereof as active ingredients as well as an agent for preventing or improving decline in brain function, comprising citrulline or a salt thereof and citicoline or a salt thereof as active ingredients is provided.
Owner:KYOWA HAKKO BIO CO LTD

Spectral method for quantifying hemoglobin fragility caused by smoking

The spectral method for quantifying hemoglobin fragility caused by smoking is based on decreased concentration of tryptophan and elevated concentrations of the biomolecules nicotinamide adenine dinucleotide (NADH), flavin adenine dinucleotide (FAD), and porphyrin in the presence of hemoglobin fragility. The method involves the steps of obtaining a blood sample from a patient who is a smoker; separating blood plasma from the samples; obtaining synchronous excitation spectra (SXS) of the blood plasma with a spectrofluorometer at a scan offset of 70 nm and at a scan offset of 10 nm; comparing the patient's SXS with the SXS of normal control samples; and diagnosing hemoglobin fragility when the excitation maxima of NADH, FAD, and porphyrin are between 30% and 70% higher than the maxima for these metabolites in the normal control samples, or when the excitation maximum for tryptophan is 60% of the control sample.
Owner:KING SAUD UNIVERSITY

Lithium secondary battery

ActiveUS10270124B2Excellent high-temperature storage and life-span propertyImprove propertiesCell electrodesLi-accumulatorsLithium metalDecreased Concentration
A lithium secondary battery including a cathode, an anode and a non-aqueous electrolyte. The cathode includes a cathode active material containing lithium-metal oxide of which at least one of metals has a concentration gradient region between a core part and a surface part thereof. The lithium-metal oxide includes elements M1, M2, and M3. M3 has a concentration gradient region with increased concentration between the core part and the surface part, M1 has a concentration gradient region with decreased concentration between the core part and the surface part, and M2 has a constant concentration from the core part and the surface part. The anode includes graphite having an average lattice distance d002 of 3.356 to 3.365 Å.
Owner:SK ON CO LTD

Food products with improved taste

The aim of the present invention is to prevent that food products, which have a decreased concentration of salt, which can be considered to be unhealthy when consumed in large amounts, from having negative taste attributes. The present invention provides such food products containing two sections, wherein the two sections are visually the same, and wherein the two sections contain a salty tastant at different concentrations in the two sections.
Owner:CONOPCO INC D B A UNILEVER

Cyclic utilization method of solar silicon wafer texturing solution

The present invention discloses a cyclic utilization method of solar silicon wafer texturing solution. The method comprises the following steps of: (1) performing etching processing of a solar siliconwafer by employing a texturing solution, employing a reverse osmosis membrance circulation separation device to separate fluosilicic acid impurities from the mixed solution after etching on an etching groove; (2) performing quantitative analysis of hydrofluoric acid and nitric acid in the mixed solution after separation of the impurities respectively by employing an automatic measurement potentiometric titrator and a nitrate ion selective electrode automatic measurement potentiostat to obtain component concentration increment or decrement of the mixed solution after etching; and (3) accordingto the component concentration increment or decrement, adding acid with decreased concentration into the etching process or the cyclic utilization to retake as the etching solution of the silicon wafer. The effectively utilization of the mixed waste acid solution discharged in the etching process allows the economical benefit to be remarkable, greatly reduces the discharge of the mixed waste acidsolution with strong acid components and have remarkable environmental benefit.
Owner:SUZHOU CRYSTAL CLEAR CHEMICAL CO LTD

Agent for preventing or improving decline in brain function

ActiveUS20150265670A1Preventing and improving decline in brain functionPreventing and improving in brain functionOrganic active ingredientsNervous disorderExercise performanceDecreased Concentration
An objection of the present invention is to provide an agent for preventing or improving decline in brain function such as decreased perception ability, decreased memory learning ability, decreased thinking ability, decreased concentration, decreased attention, decreased judgment ability, depression, and decreased exercise performance caused thereby. According to the present invention, an agent for protecting brain neuronal cells, comprising citrulline or a salt thereof and glutathione or a salt thereof as active ingredients as well as an agent for preventing or improving decline in brain function, comprising citrulline or a salt thereof and glutathione or a salt thereof as active ingredients is provided.
Owner:KYOWA HAKKO BIO CO LTD

Extractant and method for extracting and separating yttrium

An extractant and a method for the extraction and separation of yttrium are disclosed in the invention. Cations of said extractant are selected from the group of quaternary phosphonium or quaternary ammonium, and the anion is sec-octylphenoxy acetate. The extractant has a simple composition, the formulated organic phase has stable properties and can be recycling used without significantly decreased concentration. The present invention used a mixed organic phase consisting of an extractant and a diluent to extract a rare earth feed liquid containing yttrium, and then washed and back extracted it with deionized water so that the consumption of acid and alkali in all the processes of extraction, washing and back extraction was avoided. Therefore, the extraction is carried out under a low acidity and a high extraction efficiency was ensured. The organic phase can be recycling used without saponification, so that no ammonia wastewater was produced in the processes.
Owner:XIAMEN INST OF RARE EARTH MATERIALS

Method of treating decline in brain function comprising coadministration of citrulline and glutathione

ActiveUS10369186B2Preventing and improving decline in brain functionMemory behavior can be synergistically and effectively improvedOrganic active ingredientsNervous disorderCitrullineExercise performance
An objection of the present invention is to provide an agent for preventing or improving decline in brain function such as decreased perception ability, decreased memory learning ability, decreased thinking ability, decreased concentration, decreased attention, decreased judgment ability, depression, and decreased exercise performance caused thereby. According to the present invention, an agent for protecting brain neuronal cells, comprising citrulline or a salt thereof and glutathione or a salt thereof as active ingredients as well as an agent for preventing or improving decline in brain function, comprising citrulline or a salt thereof and glutathione or a salt thereof as active ingredients is provided.
Owner:KYOWA HAKKO BIO CO LTD
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