A threaded fastener has a substantially single helical thread formed upon a shank portion thereof, and a plurality of substantially saw-blade type or serrated teeth are formed upon crest portions of leading ones of individual thread portions of the helical thread. The threads of the threaded screw fastener are also characterized by means of predetermined flank angles, and such flank angles, in conjunction with the saw-blade type or serrated teeth, permit the threaded screw fastener of the present invention to be utilized within any one of a multiplicity of substrates, such as, for example, wood, metal, thermoplastics, composite materials, concrete, hard aggregate, or the like.