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Medicinal balloon catheter and preparation method thereof

A balloon catheter and drug technology, applied in balloon catheters, drug devices, other medical devices, etc., can solve the problems of expensive drug-plated stents, thrombosis in patients, adverse reactions, etc., and improve and reduce drug adsorption capacity. The effect of increasing the amount of lost and adsorbed drug

Inactive Publication Date: 2010-07-28
成都维德医疗器械有限责任公司
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, compared with ordinary bare stents that are not coated with drugs, drug-coated stents are very expensive and due to the influence of polymer materials on the coating, some patients will have thrombosis and cause serious adverse reactions
Drug-coated balloon revascularization is an improved balloon revascularization. This technique is to coat a layer of drugs on the outer surface of the balloon, send the balloon into the lesion through a catheter, expand the balloon, and make the coated drug It stays at the lesion to dilate blood vessels to keep them open. In this way, even if the patient’s blood vessels become narrowed and blocked again, the drug-coated balloon catheter can be used for secondary treatment. However, how to use the medicine as much as possible Many of the drugs coated on the outer surface of the balloon and how to keep the drug from being washed out by the blood in the blood vessel during the process of sending the balloon into the lesion through the catheter have become a difficult problem in this technology. There is no better solution

Method used

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  • Medicinal balloon catheter and preparation method thereof
  • Medicinal balloon catheter and preparation method thereof
  • Medicinal balloon catheter and preparation method thereof

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Embodiment Construction

[0022] The present invention will be further described in detail below with reference to the embodiments and accompanying drawings, but the embodiments of the present invention are not limited thereto.

[0023] see Figure 1 to Figure 2 As shown, the outer surface of the balloon of the drug balloon catheter of the present invention is a non-planar structure with concavities and convexities, and the non-planar structure is formed by grinding the surface of the balloon with an ultraviolet laser in a direction parallel to the axial direction of the drug balloon catheter. Wherein, the thickness of the wall of the balloon is 12-25 microns, and the thickness of the non-planar structure is 8-12 microns.

[0024] A method for preparing the above-mentioned drug balloon catheter, which uses a pulse scanning method to grind the outer surface of the balloon with a 10-400nm ultraviolet laser, so that the outer surface of the balloon forms a non-planar structure with unevenness, and the out...

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Abstract

The invention discloses a medicinal balloon catheter and a preparation method thereof. The balloon outside surface of the medicinal balloon catheter is grinded and processed through ultraviolet laser to form the concave-convex non-planar structure on the balloon outside surface. The gaps within the non-planar structure form a drug storage layer. The wavelength of the ultraviolet laser is within the range of 10-400nm. The wall thickness of the medicinal balloon catheter is 15-25 microns. The thickness of the non-planar structure is 8-12 microns. Owning to the concave-convex non-planar structure of the balloon outside surface of the medicinal balloon catheter in the invention, the medicinal adsorption storage capacity is fundamentally improved, namely firstly, the amount of the adsorbed medicine is greatly increased, secondly when medicine adsorbed on balloon passes through blood vessels to reach the site of lesion, the medicine adsorbed on the outer wall of the balloon can be maintained as much as possible and cannot be washed off by blood in the blood vessels and cause loss, and can be effectively transferred to the site of lesion by the balloon so as to have effectively therapeutic action. The medicinal balloon catheter of the invention can be used in not only coronary heart disease, but also various diseases caused by other narrow vessels such as lower extremity arterial stenos is or occlusion caused by diabetes.

Description

technical field [0001] The invention relates to a drug balloon catheter and a preparation method thereof. Background technique [0002] Coronary heart disease (coronary Atherosclerotic heart disease, CAHD) referred to as coronary heart disease, is the most common heart disease, refers to myocardial dysfunction and (or) organic disease caused by coronary artery stenosis and insufficient blood supply, Therefore, it is also called ischemic cardiomyopathy (IHD). The etiology is due to the formation of atherosclerotic plaques on the walls of the coronary arteries that supply the heart itself, resulting in narrowing of the lumen of the blood vessels and causing heart disease. Due to the location, length and degree of coronary artery stenosis, the clinical symptoms are also different. [0003] The treatment of coronary heart disease includes three treatment options, namely drug therapy, interventional therapy and cardiac surgery bypass surgery. Drug therapy is the most basic tre...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M25/10A61M31/00A61F2/958
Inventor 何福桂
Owner 成都维德医疗器械有限责任公司
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