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Medicinal composition for treating gynecological inflammation and application thereof

A technology of gynecological inflammation and composition, applied in the field of traditional Chinese medicine, can solve problems such as no precedent for the combined application of traditional Chinese medicine, and achieve the effects of good hemostasis, strong coordination ability, and good physical and mechanical properties

Inactive Publication Date: 2010-02-17
BEIJING HERUN INNOVATION PHARMA TECH DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

As an ideal tissue engineering biomaterial, collagen has been used in cosmetics and hemostatic medical devices, and there is no precedent for its combined application with traditional Chinese medicine

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0075] Prescription: Sophora flavescens 80g Phellodendron 50g Curcuma 70g Paeoniae Alba 80g

[0076] Collagen 5g Collagen 2g

[0077]Preparation method: crush the above four flavors, add 5 times the amount of 70% ethanol to reflux and extract twice, filter, combine, recover ethanol under reduced pressure, concentrate, dry, crush, and set aside; take 5g of carbomer, add water to swell for 24 hours , add triethanolamine to adjust the pH to 8, stir well, add the above-mentioned dry cream powder and collagen fine powder 5g, and add water to 500g, stir well, remove air bubbles, and make a gel.

[0078] Note: Collagen is made from pigskin by enzymatic hydrolysis with neutral pepsin, and its relative molecular weight is below 8kD.

Embodiment 2

[0080] Prescription: Sophora flavescens 100g, herb 50g, pepper 50g, borneol 2g

[0081] Motherwort 65g White moss bark 30g Collagen 15g

[0082] Preparation method: the above-mentioned Qiwei, Atractylodes atractylodes, and Zanthoxylum bungeanum are used to obtain volatile oil by steam distillation; Sophora flavescens, motherwort, and white moss bark are decocted twice with 8 times the amount of water, filtered, combined, concentrated, dried, crushed, and set aside; Heat 400g of Vaseline, 100g of lanolin and an appropriate amount of liquid paraffin at 150°C for 1 hour, filter, let cool to 50°C, add volatile oil, stir well, then add the above dry paste fine powder, borneol and collagen fine powder 15g, and vibrate Ultrafine pulverization for 15 minutes in a type ultrafine pulverizer, fully mixed evenly, and made into an ointment.

[0083] Note: Collagen is made from cowhide by biomimetic enzymatic hydrolysis, and its relative molecular weight is below 5kD.

Embodiment 3

[0085] Prescription: Sanbaicao 70g, Smilax tuckahoe 50g, mountain bean root 65g, mountain silver flower 80g

[0086] Qianjin pull 60g, single-sided needle 70g, golden cherry root 80g, collagen 25g

[0087] Preparation method: the above-mentioned Bawei, Shandougen, Qianjinba, and Jinyinggen add 5 times the amount of 50% ethanol to reflux and extract 3 times, merge, filter, recover ethanol under reduced pressure, concentrate, dry, pulverize, and set aside; the obtained medicinal residues are mixed with three Add 8 times the amount of water to decoct Baicao baicao, Smilax smilax, and Duanmianzhen together twice, 2 hours each time, combine the decoction, filter, concentrate under reduced pressure, dry, pulverize, and set aside. Separately take 200 g of polyethylene glycol-4000, heat and melt, add the above-mentioned dry paste fine powder and collagen fine powder, stir well, put it in a mold, cool down, and make a suppository.

[0088] Note: Collagen is prepared from pigskin...

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PUM

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Abstract

The invention discloses a medicinal composition for treating gynecological inflammation, and belongs to the field of Chinese medicament. The medicinal composition consists of collagen and / or Chinese medicaments for releasing toxin and sterilizing such as collagen and lizardtail, glabrous greenbrier rhizome, Vietnamese sophora root and the like which are prepared into a plurality of dosage forms bycombining the prior art, and is mainly used for treating vaginitis, pelvic inflammation, urethritis and cervicitis diseases. The technical scheme overcomes the defects that the prior externally-applied preparations such as lotion, gel, suppository, ointment and the like have extremely slow response, longer disease course, repeated outbreak and the like, and creatively combines and applies the collagen and the Chinese medicament, can accelerate the healing of ulcer and erosion faces caused by the inflammation, and can greatly shorten the required time for tissue repair.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating various gynecological inflammations, which is composed of collagen and / or collagen and traditional Chinese medicine, and belongs to the field of traditional Chinese medicine. Background technique [0002] Inflammation of female reproductive organs is collectively referred to as gynecological inflammation, which is one of the most common diseases in women, roughly including vulvitis, vaginitis, pelvic inflammatory disease, cervicitis, urethritis, etc. More than 70% of women in our country suffer from gynecological diseases to varying degrees, and the knowledge of gynecological health care is extremely scarce. It is understood that 39% of young women suffer from gynecological inflammation; among middle-aged women, 69% suffer from or have suffered from gynecological inflammation. It can be seen that the incidence rate of gynecological inflammation in my country is relatively high, and ther...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/39A61K38/17A61P15/00A61P15/02A61P13/02A61K36/906A61K36/904A61K36/896A61K36/804A61K36/78A61K36/75A61K36/758A61K36/756A61K36/736A61K36/71A61K36/708A61K36/58A61K36/532A61K36/534A61K36/539A61K36/489A61K36/48A61K36/35A61K36/31A61K36/296A61K36/28A61K36/23A61K36/185A61K33/06A61K31/045
Inventor 武建卓柴金苗
Owner BEIJING HERUN INNOVATION PHARMA TECH DEV
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