89 results about "P-hydroxybenzaldehyde" patented technology

The invention belongs to the technical field of preparation of polyurethane elastomers, and discloses a water-resistant self-repairing polyurethane elastomer, a preparation method thereof and application of the water-resistant self-repairing polyurethane elastomer in a humidity sensor. The method comprises the following steps: S1, dissolving 4, 4 '-diaminodiphenylmethane and p-hydroxybenzaldehyde in absolute ethyl alcohol, and carrying out a Schiff base reaction to generate micromolecular MDOH with an imine bond structure, which is used as a chain extender of polyurethane; s2, reacting hydroxyl-terminated polybutadiene with isophorone diisocyanate at 60 DEG C to generate a prepolymer, and adding MDOH and glyceryl monostearate into the obtained prepolymer for chain extension; mDOH is introduced, so that the material has excellent self-repairing capability, and glyceryl monostearate is beneficial to further improving the self-repairing capability and water resistance. In addition, the humidity sensor based on the polyurethane elastomer can show good sensing performance.

The invention discloses a washable anti-wrinkle fabric and a preparation method thereof, and relates to the technical field of fabrics. When the washable anti-wrinkle fabric is prepared, a pretreated cotton fabric, triethyl phosphite and 4-amino-3-nitrobenzyl alcohol react to prepare a modified cotton fabric; enabling the nano titanium dioxide wrapped by the chitosan to react with p-hydroxybenzaldehyde to prepare modified nano titanium dioxide; reacting the modified cotton fabric with the modified nano titanium dioxide to obtain a modified cotton gray fabric; and finally, carrying out after-finishing by using 1-chloromethyl-3-trifluoromethyl benzene to obtain the washable anti-wrinkle fabric. The washing-resistant and crease-resistant fabric prepared by the invention has excellent washing resistance, crease resistance, flame retardance and ultraviolet resistance.

The invention discloses a Schiff base epoxy oligomer chain extender as well as a preparation method and application thereof. The preparation method of the Schiff base epoxy oligomer chain extender comprises the following steps: adding p-hydroxybenzaldehyde and p-hydroxyaniline into ethanol, reacting at 30-70 DEG C for 2-5 hours, and performing suction filtration to obtain a 4-((4-hydroxybenzylidene) amino) phenol intermediate; and mixing the 4-((4-hydroxybenzylidene) amino) phenol intermediate, epoxy chloropropane and a catalyst, reacting at 80-100 DEG C for 3-7 hours, cooling to 50-70 DEG C, dropwise adding a strong alkali solution, reacting for 4-8 hours after dropwise adding, washing with deionized water, retaining an organic layer, and carrying out rotary evaporation on the organic layer to obtain the product. The rigidity, toughness and heat resistance of the modified nylon 6 prepared by applying the Schiff base epoxy oligomer chain extender are improved, and the modified nylon 6 still has processability similar to that of nylon 6.

The invention discloses a nerve cell senescence resisting medicine containing p-hydroxybenzaldehyde and application thereof.The p-hydroxybenzaldehyde is adopted as the only active substance, and the p-hydroxybenzaldehyde can reduce accumulation of DNA damage in cells, reduce activity of beta-galactosidase in the cells and slow down reduction of cell metabolic capacity, so that the nerve cell senescence resisting medicine is obtained. Therefore, the senescence of nerve cells is effectively slowed down, the cognitive function is improved, and a potential treatment effect is achieved in neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease.

The invention provides a preparation method of a cross-linking agent, the cross-linking agent and application of the cross-linking agent, a precursor HAPCP is prepared from phosphonitrilic chloride trimer and p-hydroxybenzaldehyde, then chain extension is performed on the precursor HAPCP and aminoethyl acrylate hydrochloride to obtain a solid substance D, and finally, the target cross-linking agent is prepared from the solid substance D and DOPO. The molecular formula of the target cross-linking agent is C150H138N9O24P9, the cross-linking agent prepared by the process contains two flame-retardant groups, namely cyclotriphosphazene and DOPO, and also contains a large amount of acrylate groups, and in the production process of the flame-retardant unsaturated polyester resin, the flame-retardant unsaturated polyester resin has excellent flame-retardant property and flame-retardant property. Two non-halogen flame-retardant groups, namely cyclotriphosphazene and DOPO, can be simultaneously introduced into an unsaturated polyester resin matrix through the cross-linking agent, the flame retardance of the flame-retardant unsaturated polyester resin can be remarkably improved under the synergism of the two flame-retardant groups, the cross-linking requirement of unsaturated polyester can be met, the flame-retardant property requirement can also be met, and the cross-linking agent has the advantages of being high in applicability, low in cost and the like. The method conforms to the green chemistry concept and is convenient to popularize and implement.

The invention discloses a flame-retardant corrosion-resistant coating and a preparation method thereof, and relates to the technical field of fluorocarbon resin powder coatings. The flame-retardant corrosion-resistant coating comprises the following raw materials in parts by weight: 15-25 parts of fluorocarbon resin, 40-50 parts of epoxy resin, 3-5 parts of a curing agent, 5-7 parts of a reinforcing agent, 4-6 parts of a corrosion inhibitor, 6-8 parts of filler, 1-2 parts of a flatting agent and 0.5-1 part of benzoin. The preparation method comprises the following steps: reacting phosphonitrilic chloride trimer with p-hydroxybenzaldehyde to generate an intermediate 1, reacting the intermediate 1 with p-aminobenzoic acid to generate an intermediate 2, and reacting the intermediate 2 with 2-heptyl ethylene oxide to generate the reinforcing agent. The flame-retardant corrosion-resistant coating prepared by the invention has excellent mechanical properties, corrosion resistance, aging resistance and flame retardance.

The invention relates to the technical field of cosmetic raw materials, in particular to a skin care composition based on saccharomycetes fermentation lysate filtrate and a preparation method. The quaternary ammonium salt antibacterial product is obtained by adding potassium carbonate, a 1, 4-dibromobutane solution, a bio-phenol solution and trimethylamine. And taking absolute ethyl alcohol, a paeonol solution, a sodium hydroxide solution, a p-hydroxybenzaldehyde solution, absolute ethyl alcohol and an iodine elementary substance as raw materials to obtain a flavone product. And adding the flavonoid product, the quaternary ammonium salt antibacterial product and the anti-inflammatory chalcone into the embedding liquid to obtain the composite embedding product. And finally, adding the yeast fermentation lysate filtrate, the composite embedding product, hydrolyzed procyanidine, sodium hyaluronate, allantoin, butanediol, a preservative and deionized water to obtain a finished product. The finished product prepared by the invention has good antibacterial performance and anti-inflammatory performance, so that the finished product has a wide application prospect in the field of cosmetic raw materials.

The invention relates to the field of pipes, and discloses a heat-resistant high-strength MPP cable protection pipe and a preparation method thereof.The cable protection pipe comprises polypropylene resin, composite filler, modified layered lanthanum phenylphosphonate and auxiliaries; the composite filler is prepared by carrying out amino functional covalent modification on halloysite nanotubes by using a modified silane coupling agent, then carrying out protonation treatment and carrying out cation exchange on nano montmorillonite grafted with the modified silane coupling agent, and the modified silane coupling agent is prepared by reacting gamma-methacryloxypropyltrimethoxysilane with polyether amine; the modified layered lanthanum phenylphosphonate is prepared by grafting and modifying the surface of the layered lanthanum phenylphosphonate by using a cyclotriphosphazene substitute, the cyclotriphosphazene substitute is prepared by reacting 4-amino-1, 2, 4-triazole with p-hydroxybenzaldehyde and then substituting with phosphonitrilic chloride trimer, and the prepared MPP cable protection tube has the advantages of good tensile property, high impact resistance, high heat resistance, good flame retardancy, good flame retardancy and good flame retardancy. Meanwhile, excellent flame retardance and antibacterial effect are achieved.

The invention discloses a preparation method of a cyclotriphosphazene Schiff base carboxylic acid rare earth complex and application of the cyclotriphosphazene Schiff base carboxylic acid rare earth complex in preparation of a flame-retardant high polymer material. The cyclotriphosphazene Schiff base carboxylic acid rare earth complex is prepared by reacting raw materials including p-hydroxybenzaldehyde, anhydrous potassium carbonate, phosphonitrilic chloride trimer, p-aminobenzoic acid and rare earth chloride heptahydrate. The cyclotriphosphazene Schiff base carboxylic acid rare earth complex prepared by the invention has the effects of catalyzing char formation and capturing free radicals based on the combined action of rare earth elements and phosphorus elements, has an efficient flame retardant effect, is small in addition amount, and can effectively reduce the total addition amount of the flame retardant when being compounded with other halogen-free flame retardants.

A preparation method of the bio-based degradable high-temperature-resistant benzoxazine resin comprises the following steps: firstly, mixing a primary amine compound and an aldehyde compound A, and stirring and reacting for 10-60 minutes at the temperature of 90-120 DEG C to generate a triazine compound; then adding a triazine compound, a bisphenol compound containing a hydroxymethyl diacetal structure synthesized from a bio-based raw material, and an aldehyde compound B into an organic solvent, and carrying out a stirring reaction at 60-90 DEG C for 1-15 h; after the reaction is finished, separating, purifying and drying a reaction product to obtain a benzoxazine monomer; the bisphenol compound containing the hydroxymethyl diacetal structure is selected from xylitol dicondensation p-hydroxy benzaldehyde or xylitol dicondensation m-hydroxy benzaldehyde; and finally, heating and curing the obtained benzoxazine monomer to obtain the benzoxazine resin. The benzoxazine resin prepared by the invention not only has excellent chemical degradability, but also has good high temperature resistance, and the highest glass transition temperature can reach 305 DEG C.

The invention relates to the technical field of water treatment, and discloses a scale inhibition and dispersion agent for treating industrial circulating water and a preparation method thereof.The scale inhibition and dispersion agent is prepared from 2-[(2-aminoethyl) amino] sodium ethanesulfonate, p-hydroxybenzaldehyde, methoxy polyethylene glycol acrylate and beta-cyclodextrin as raw materials. Sodium alkenyl sulfonate long-chain cyclodextrin is obtained through reductive amination, addition and esterification and initiates copolymerization with acrylic acid and itaconic acid to obtain the scale inhibition and dispersion agent of a comb-type structure, and a chelate is dissolved or suspended in a solution through carboxyl, sulfo group and ether group in the structure of the scale inhibition and dispersion agent, so that the effect of effectively dispersing ferric oxide is achieved; polyethylene glycol long chains and beta-cyclodextrin have large steric hindrance and can be stretched, the probability that CaCO3 and BaSO4 crystals collide with each other can be reduced, salt ions and other molecules causing corrosion in a solution are difficult to get close to the metal surface, and the corrosion inhibitor has a good corrosion inhibition effect, is free of phosphorus and environmentally friendly and can be widely applied to an industrial circulating water treatment system.

The invention discloses a method for preparing a wear-resistant high-strength plastic, and relates to the field of plastic technology. The present invention first prepares a matting agent from 1H-pyrrole-3,4-dicarboxylic acid, 1,2,3-tribromopropane, and p-hydroxybenzaldehyde, and constructs a micro-nano rough plane on the plastic surface through a surface containing a cone-shaped protrusion and a porous microsphere fibrous structure, enhances the multiple reflections of light, and synergizes with the light-absorbing structure to make the plastic have a matting effect; after preparing elastic polystyrene from N-allylmaleimide, styrene, and 1,5-hexadiene, the matting agent is reacted to prepare an impact-resistant base material, and the plastic has an impact-resistant effect through the yield deformation effect of the soft phase of the elastic polystyrene and the rigid support effect of the hard phase, the dispersion effect of the matting agent, and the common force effect; the impact-resistant base material is mixed with other additives to prepare a wear-resistant high-strength plastic. The plastic prepared by the present invention has a matting and impact-resistant effect.

The present application relates to the technical field of pesticides, and discloses a chromene aryl hydrazide derivative, a preparation method and application thereof, a structural general formula of the chromene aryl hyydrazide derivative is as formula (I); the preparation method is as follows: taking p-hydroxybenzaldehyde as raw material, and obtaining the chromene aryl hydrazide compound through substitution reaction, cyclization reaction, oxidation reaction, acylation reaction and hydrazinolysis reaction. The chromene aryl hydrazide compound is used for preparing an agricultural bacteriostatic agent. The present application combines aryl hydrazine and chromene skeleton by using the pharmacophore splicing principle in medicinal chemistry, and designs and synthesizes a series of chromene aryl hydrazide compounds. The bacteriostatic activity test result shows that the compounds have excellent bacteriostatic activity, and can be used as active ingredients for preparing a plant pathogenic fungus fungicide.

The invention discloses a low-temperature dew point neutralizing corrosion inhibitor and a preparation method thereof, belonging to the technical field of corrosion protection in a petroleum processing process, comprising a Mannich base derivative, an organic amine compound and a solvent, wherein the Mannich base derivative uses 2,4-dihydroxy-6-methoxy-3-methylacetophenone as a raw material, undergoes Claisen-Schmidt condensation with p-hydroxybenzaldehyde under alkaline conditions to obtain an intermediate, and then undergoes a Mannich reaction with N-ethylpiperazine to obtain the intermediate; the invention performs modification and adjustment on the basis of the existing Mannich base to obtain a neutralizing corrosion inhibitor having both good corrosion protection performance and anti-emulsification performance.

The application relates to the field of biological medicine, and discloses an active oxygen response thione aldehyde linker as well as a preparation method and application thereof. The thione aldehyde linker structure is a thione aldehyde structure with a p-hydroxyphenyl as a center. The thione aldehyde carbon atom is connected with two -CH2CH2COOH groups through a sulfur atom. The preparation method of the active oxygen response thione aldehyde linker comprises the following steps: dissolving 3-mercapto propionic acid and p-hydroxybenzaldehyde in ethyl acetate, adding trifluoroacetic acid as a catalyst, stirring and reacting at room temperature, and after the reaction is completed, the thione aldehyde linker is obtained through separation and purification. The thione aldehyde linker can respond to the increased ROS level in a tumor microenvironment, is broken under a high ROS condition, and thus realizes the release of a drug molecule connected therewith, which is beneficial to realizing the specific release of the drug at a tumor site.

The invention discloses a semi-prefabricated plastic runway foaming coiled material, and relates to the technical field of plastic runways. According to the preparation method, hindered amine 4-amino-2, 2, 6, 6-tetramethylpiperidine reacts with aldehyde groups of p-hydroxybenzaldehyde to generate piperidine ring-containing Schiff base, the piperidine ring-containing Schiff base is grafted with 9, 10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide, and then hindered phenol 3, 5-bis (tert-butyl)-4-hydroxybenzene propionyl chloride reacts with hydroxyl groups of p-hydroxybenzaldehyde to obtain the 9, 10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide grafted 9, 10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide grafted 9, 10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide grafted 9, 10-dihydro-9-oxa-10- The flame retardant containing hindered phenol and hindered amine at the same time is generated, and by adding the flame retardant into polyurethane, on one hand, the flame retardant property of the plastic track is improved, and on the other hand, the anti-aging property of the plastic track is also improved.

The invention relates to an organic silicon heat conduction material, in particular to a repairable liquid crystal type organic silicon heat conduction material and a preparation method and application thereof. P-hydroxybenzaldehyde, potassium carbonate, potassium iodide and halogenated olefin are used for preparing a monomer M1; then reacting the monomer M1 with aromatic diamine to prepare a diene liquid crystal monomer M2; and finally, reacting the diene liquid crystal monomer M2 with hydrogen-containing silicone oil to prepare the organic silicon heat-conducting material. The repairable liquid crystal type organic silicon heat conduction material has excellent heat conduction performance and electrical performance, can repair damaged materials in a proper temperature range through an exchange reaction of imine bonds, and is suitable for preparation of heat conduction components and / or heat conduction packaging of circuit boards.

The invention relates to a method for preparing trilobatin by taking hesperidin as a raw material, which comprises the following steps of: 1, hydrolyzing the hesperidin with the content of more than 90 percent as the raw material to remove rhamnose to obtain an intermediate 1; step 2, reacting the obtained intermediate 1 with p-hydroxybenzaldehyde to obtain an intermediate 2; 3, the obtained intermediate 2 is subjected to a reduction reaction and then purified, and the product trilobatin is obtained. The hesperidin is used as the main raw material to prepare the trilobatin, the hesperidin serving as the raw material is sufficient in source and low in cost and meets market requirements and has competitive advantages, and the preparation method is easy to operate and suitable for industrial production.

The invention relates to the field of chemical synthesis, in particular to a synthetic method and application of vanillin and derivatives thereof. The synthesis method comprises the following synthesis steps: S1, bromination: reacting p-hydroxybenzaldehyde with a brominating agent to obtain a mixture of 3-bromo-4-hydroxybenzaldehyde and 3, 5-dibromo-4-hydroxybenzaldehyde; s2, separation and purification: taking the mixture of the 3-bromo-4-hydroxybenzaldehyde and the 3, 5-dibromo-4-hydroxybenzaldehyde, sequentially carrying out recrystallization and melt crystallization, and separating the 3-bromo-4-hydroxybenzaldehyde and the 3, 5-dibromo-4-hydroxybenzaldehyde; s3, etherification: taking 3-bromo-4-hydroxybenzaldehyde to react with sodium methoxide or sodium ethoxide, so as to obtain an etherified product. According to the method disclosed by the invention, high-purity 3-bromo-4-hydroxybenzaldehyde and 3, 5-dibromo-4-hydroxybenzaldehyde are obtained through recrystallization coupled with melt crystallization separation; the whole process is free of material loss, safe and environment-friendly.

The present invention discloses a method for biocatalytic synthesis of p-hydroxybenzylideneacetone, belonging to the technical field of bioengineering. First, a recombinant Escherichia coli overexpressing deoxyriboaldolase was constructed, and the whole cells and immobilized cells of this recombinant strain were used to catalyze p-hydroxybenzaldehyde to generate p-hydroxybenzylideneacetone with acetone as the reaction medium. When the whole cells of the recombinant Escherichia coli provided by the present invention were used for catalytic preparation of p-hydroxybenzylideneacetone, the yield reached 19 g / L, and the molar conversion rate of p-hydroxybenzaldehyde reached 99.8%. The method for preparing p-hydroxybenzylideneacetone by the biological method provided by the present invention has the advantages of mild reaction conditions, simple process, easy control, etc., and is also beneficial to environmental protection and easy to promote and apply.

The invention discloses asymmetric ester group-containing dicarboxylic acid, polyarylester, a preparation method and application. The asymmetric ester group-containing dicarboxylic acid is prepared from 4-formylbenzoic acid or a derivative thereof and p-hydroxybenzaldehyde or a derivative thereof through an esterification reaction and an aldehyde group oxidation reaction in sequence; the polyarylester is obtained by copolymerizing asymmetric ester group-containing dicarboxylic acid and aromatic amine; the main chain structure of the polyarylester contains heteroaromatic rings, so that the interaction force among polyarylester molecules is remarkably enhanced, the glass transition temperature and the thermal decomposition temperature of the polyarylester are greatly improved, and the polyarylester has excellent thermal stability and high-temperature-resistant application prospects, is remarkably higher than those of existing polyarylester materials, and shows certain toughness; meanwhile, the polyarylester has excellent gas separation performance after film formation, particularly has good selectivity to hydrogen, and is obviously superior to that of traditional polyarylester.

The invention provides a method for preparing p-hydroxystyrene, which comprises the following steps: reacting a raw material p-hydroxybenzaldehyde with a raw material dimethylacetamide in an organic solvent in a reactor under the catalysis of a basic catalyst to generate p-hydroxystyrene, wherein the method does not include reacting p-hydroxybenzaldehyde with malonic acid to produce p-hydroxystyrene.

The invention discloses a synthesis method and application of a pesticide and medical intermediate phenolic hydroxyl group-containing alkenyl oxime ether compound, and the synthesis method of the phenolic hydroxyl group-containing alkenyl oxime ether compound comprises the following steps: carrying out aldol condensation on p-hydroxy benzaldehyde and acetone under the action of alkali to obtain a phenolic hydroxyl group-containing alkenyl ketone compound 1; reacting the compound 1 with dimethyl tert-butyl chlorosilane (TBSCl) under the action of imidazole, so as to obtain a phenolic hydroxyl alkenyl ketone compound 2 protected by a silicon group; reacting the compound 2 with hydroxylamine hydrochloride under the action of alkali to obtain a silicon group protected alkenyl ketoxime compound 3; and carrying out nucleophilic substitution reaction on the compound 3 and a substituted benzyl bromide compound 4 under the action of alkali to prepare a phenolic hydroxyl group-containing alkenyl oxime ether compound 5. The phenolic hydroxyl-containing alkenyl oxime ether compound 5 or the preparation thereof can be used for preventing and treating diseases caused by common plant pathogenic fungi such as oomycetes, phycomycetes and ascomycetes on various crops.

The invention discloses a high-strength modified polypropylene composite material and a preparation process thereof, and relates to the technical field of polypropylene composite materials. The high-strength modified polypropylene composite material comprises the following raw materials in parts by weight: 60-70 parts of polypropylene, 15-18 parts of modified glass fibers and 5-6 parts of a thiazolyl phosphorus-containing flame retardant. The preparation method comprises the following steps: sequentially reacting phosphorus oxychloride with p-hydroxybenzaldehyde and 2-aminothiazole to obtain a thiazolyl phosphorus-containing flame retardant; the preparation method comprises the following steps: sequentially reacting glass fibers with 3-chloropropyltriethoxysilane and tetraethylenepentamine to prepare aminated glass fibers; and carrying out a reaction on the aminated glass fiber, acrylate-based hindered phenol and 2-[3-(2H-benzotriazole-2-yl)-4-hydroxyphenyl] ethyl 2-methacrylate to prepare the modified glass fiber. The modified glass fiber and the thiazolyl phosphorus-containing flame retardant are added into polypropylene, so that the polypropylene composite material is endowed with excellent flame retardance, weather resistance and mechanical properties.

The invention provides p-hydroxybenzaldehyde (PHBA) modified macroporous chloromethylated polystyrene (CMPs) as well as a preparation method and application thereof, and belongs to the technical field of adsorbents. The preparation method comprises the following steps: introducing an oxygen-containing aromatic functional compound PHBA to modify CMPs, firstly carrying out a nucleophilic substitution reaction, and then carrying out a Friedel-Crafts alkylation reaction to prepare the super-crosslinked resin PHBA-HCPs. Due to the good specific surface area and the introduction of aromatic hydrocarbon functional groups containing heteroatoms (especially oxygen-enriched groups), the adsorption performance of the polymer on aniline in an aqueous solution is greatly improved.

The invention discloses a synthesis method of an antibody-coupled drug connexon with an aldehyde group, and belongs to the technical field of chemical synthesis of drugs. The preparation method comprises the following steps: synthesizing 4-(4-formylphenoxy) butyric acid by taking p-hydroxybenzaldehyde as an initial raw material, then carrying out amidation reaction on the 4-(4-formylphenoxy) butyric acid and Boc-ethylenediamine to generate 4-(4-formylphenoxy)-N-(2-pivalamidoethyl) butyramide, and carrying out acidic deprotection reaction to remove Boc groups, thereby obtaining the 4-(4-formylphenoxy)-N-(2-pivalamidoethyl) butyramide. According to the present invention, with the method, the basis is provided for the variety expansion of the antibody-coupled drug connexon, and the good application prospect is provided.

The invention relates to the technical field of organic synthesis, and particularly discloses a preparation method of 4-isopropenylphenol, which comprises the following steps: hydroxyl protection: under the action of stirring, adding p-hydroxyacetophenone or p-hydroxybenzaldehyde into a solvent A, then adding a hydroxyl protective agent and alkaline ion exchange resin, carrying out heat preservation reaction at 10-15 DEG C for 3-4 hours, filtering, washing, and drying to obtain 4-isopropenylphenol; filtering, extracting and concentrating to obtain an intermediate 1; grignard reaction: under the stirring action, adding the intermediate 1 into a solvent B, heating to 35-45 DEG C, then dropwise adding a Grignard reagent, continuously carrying out heat preservation reaction for 5-6 hours, after the reaction is finished, adding a hydrochloric acid solution, standing for phase separation, and concentrating to obtain an intermediate 2; the Grignard reagent is isopropyl magnesium chloride or methyl magnesium chloride. According to the preparation method provided by the invention, the 4-isopropenylphenol with the yield being greater than or equal to 60% and the purity being greater than or equal to 98% can be obtained, the reaction operation is simple, and large-scale industrial production is facilitated.

The invention relates to the technical field of manganese oxide catalysts, in particular to a SiO2-loaded rare earth-doped Mn oxide catalyst as well as preparation and application thereof. The SiO2 loaded rare earth doped Mn oxide catalyst provided by the invention has a large number of surface oxygen holes, and can convert herbal lignin into high value-added aromatic aldehydes such as p-hydroxybenzaldehyde, vanillin and the like at high selectivity and high conversion rate under mild conditions; rare earth elements and Mn in the crystal structure of the catalyst interact to improve the activity of the catalyst, and furthermore, insufficient exposure of an active center caused by agglomeration of the catalyst is avoided through loading of SiO2, so that the reaction selectivity is effectively ensured, and the reaction efficiency is improved.

The invention provides a halogen-free phosphorus flame retardant as well as a preparation method and application thereof, and belongs to the technical field of flame retardants. The preparation method comprises the following steps: mixing a hydroxyl-containing compound, an acid-binding agent and an organic solvent to obtain a mixed solution; dropwise adding pyrophosphoryl chloride into the mixed solution, and reacting to obtain a reaction product; and carrying out post-treatment on the reaction product to obtain the halogen-free phosphorus flame retardant. The hydroxyl-containing compound comprises one or more of epoxy butanol, glycidol, syringaldehyde, vanillin and p-hydroxybenzaldehyde. The halogen-free phosphorus-based flame retardant disclosed by the invention is a flame retardant with a new structure and has an epoxy group capable of participating in a co-curing reaction of epoxy resin; the preparation method of the flame retardant is simple, the flame retardant is prepared from hydroxyl-containing compounds such as glycidol and pyrophosphoryl chloride under the action of an organic solvent and an acid-binding agent through a one-step synthesis method, and a target object can be conveniently and rapidly prepared.

The present application relates to a kind of phosphorus of p-hydroxybenzaldehyde PPHBA compound and its auxiliary preparation octreotide method, belong to organic synthesis technical field.The present application also provides a kind of phosphorus of p-hydroxybenzaldehyde PPHBA compound in preparation octreotide application, and a kind of phosphorus of p-hydroxybenzaldehyde compound auxiliary preparation octreotide method.The present application is with diphenylphosphine acyl oxy benzaldehyde DPOBA as carrier auxiliary octreotide phase synthesis method, using the auxiliary precipitation effect of DPOBA carrier, through liquid phase reaction with equivalent amino acid coupling and the strategy of Fmoc protection, optimize and simplify the preparation method of octreotide, verify the recyclability and reusability of DPOBA carrier.