33 results about "P-hydroxybenzaldehyde" patented technology

The invention discloses a flame-retardant corrosion-resistant coating and a preparation method thereof, and relates to the technical field of fluorocarbon resin powder coatings. The flame-retardant corrosion-resistant coating comprises the following raw materials in parts by weight: 15-25 parts of fluorocarbon resin, 40-50 parts of epoxy resin, 3-5 parts of a curing agent, 5-7 parts of a reinforcing agent, 4-6 parts of a corrosion inhibitor, 6-8 parts of filler, 1-2 parts of a flatting agent and 0.5-1 part of benzoin. The preparation method comprises the following steps: reacting phosphonitrilic chloride trimer with p-hydroxybenzaldehyde to generate an intermediate 1, reacting the intermediate 1 with p-aminobenzoic acid to generate an intermediate 2, and reacting the intermediate 2 with 2-heptyl ethylene oxide to generate the reinforcing agent. The flame-retardant corrosion-resistant coating prepared by the invention has excellent mechanical properties, corrosion resistance, aging resistance and flame retardance.

The invention relates to the field of pipes, and discloses a heat-resistant high-strength MPP cable protection pipe and a preparation method thereof.The cable protection pipe comprises polypropylene resin, composite filler, modified layered lanthanum phenylphosphonate and auxiliaries; the composite filler is prepared by carrying out amino functional covalent modification on halloysite nanotubes by using a modified silane coupling agent, then carrying out protonation treatment and carrying out cation exchange on nano montmorillonite grafted with the modified silane coupling agent, and the modified silane coupling agent is prepared by reacting gamma-methacryloxypropyltrimethoxysilane with polyether amine; the modified layered lanthanum phenylphosphonate is prepared by grafting and modifying the surface of the layered lanthanum phenylphosphonate by using a cyclotriphosphazene substitute, the cyclotriphosphazene substitute is prepared by reacting 4-amino-1, 2, 4-triazole with p-hydroxybenzaldehyde and then substituting with phosphonitrilic chloride trimer, and the prepared MPP cable protection tube has the advantages of good tensile property, high impact resistance, high heat resistance, good flame retardancy, good flame retardancy and good flame retardancy. Meanwhile, excellent flame retardance and antibacterial effect are achieved.

The present application relates to the technical field of pesticides, and discloses a chromene aryl hydrazide derivative, a preparation method and application thereof, a structural general formula of the chromene aryl hyydrazide derivative is as formula (I); the preparation method is as follows: taking p-hydroxybenzaldehyde as raw material, and obtaining the chromene aryl hydrazide compound through substitution reaction, cyclization reaction, oxidation reaction, acylation reaction and hydrazinolysis reaction. The chromene aryl hydrazide compound is used for preparing an agricultural bacteriostatic agent. The present application combines aryl hydrazine and chromene skeleton by using the pharmacophore splicing principle in medicinal chemistry, and designs and synthesizes a series of chromene aryl hydrazide compounds. The bacteriostatic activity test result shows that the compounds have excellent bacteriostatic activity, and can be used as active ingredients for preparing a plant pathogenic fungus fungicide.

The application relates to the field of biological medicine, and discloses an active oxygen response thione aldehyde linker as well as a preparation method and application thereof. The thione aldehyde linker structure is a thione aldehyde structure with a p-hydroxyphenyl as a center. The thione aldehyde carbon atom is connected with two -CH2CH2COOH groups through a sulfur atom. The preparation method of the active oxygen response thione aldehyde linker comprises the following steps: dissolving 3-mercapto propionic acid and p-hydroxybenzaldehyde in ethyl acetate, adding trifluoroacetic acid as a catalyst, stirring and reacting at room temperature, and after the reaction is completed, the thione aldehyde linker is obtained through separation and purification. The thione aldehyde linker can respond to the increased ROS level in a tumor microenvironment, is broken under a high ROS condition, and thus realizes the release of a drug molecule connected therewith, which is beneficial to realizing the specific release of the drug at a tumor site.

The invention provides a method for preparing p-hydroxystyrene, which comprises the following steps: reacting a raw material p-hydroxybenzaldehyde with a raw material dimethylacetamide in an organic solvent in a reactor under the catalysis of a basic catalyst to generate p-hydroxystyrene, wherein the method does not include reacting p-hydroxybenzaldehyde with malonic acid to produce p-hydroxystyrene.

The invention discloses a high-strength modified polypropylene composite material and a preparation process thereof, and relates to the technical field of polypropylene composite materials. The high-strength modified polypropylene composite material comprises the following raw materials in parts by weight: 60-70 parts of polypropylene, 15-18 parts of modified glass fibers and 5-6 parts of a thiazolyl phosphorus-containing flame retardant. The preparation method comprises the following steps: sequentially reacting phosphorus oxychloride with p-hydroxybenzaldehyde and 2-aminothiazole to obtain a thiazolyl phosphorus-containing flame retardant; the preparation method comprises the following steps: sequentially reacting glass fibers with 3-chloropropyltriethoxysilane and tetraethylenepentamine to prepare aminated glass fibers; and carrying out a reaction on the aminated glass fiber, acrylate-based hindered phenol and 2-[3-(2H-benzotriazole-2-yl)-4-hydroxyphenyl] ethyl 2-methacrylate to prepare the modified glass fiber. The modified glass fiber and the thiazolyl phosphorus-containing flame retardant are added into polypropylene, so that the polypropylene composite material is endowed with excellent flame retardance, weather resistance and mechanical properties.

The invention provides a halogen-free phosphorus flame retardant as well as a preparation method and application thereof, and belongs to the technical field of flame retardants. The preparation method comprises the following steps: mixing a hydroxyl-containing compound, an acid-binding agent and an organic solvent to obtain a mixed solution; dropwise adding pyrophosphoryl chloride into the mixed solution, and reacting to obtain a reaction product; and carrying out post-treatment on the reaction product to obtain the halogen-free phosphorus flame retardant. The hydroxyl-containing compound comprises one or more of epoxy butanol, glycidol, syringaldehyde, vanillin and p-hydroxybenzaldehyde. The halogen-free phosphorus-based flame retardant disclosed by the invention is a flame retardant with a new structure and has an epoxy group capable of participating in a co-curing reaction of epoxy resin; the preparation method of the flame retardant is simple, the flame retardant is prepared from hydroxyl-containing compounds such as glycidol and pyrophosphoryl chloride under the action of an organic solvent and an acid-binding agent through a one-step synthesis method, and a target object can be conveniently and rapidly prepared.

The application discloses a kind of fire-retardant corrosion-resistant coating and preparation method thereof, it is related to fluorocarbon resin powder coating technical field.The fire-retardant corrosion-resistant coating includes the following weight parts of raw materials: fluorocarbon resin 15-25 parts, epoxy resin 40-50 parts, curing agent 3-5 parts, reinforcing agent 5-7 parts, corrosion inhibitor 4-6 parts, filler 6-8 parts, leveling agent 1-2 parts, benzoin 0.5-1 part.The application is generated by the reaction of hexachlorocyclotriphosphazene and p-hydroxybenzaldehyde intermediate 1, intermediate 1 is generated by the reaction of p-aminobenzoic acid and intermediate 2, and intermediate 2 is generated by the reaction of 2-heptyl oxirane and reinforcing agent.The fire-retardant corrosion-resistant coating prepared by the application has excellent mechanical properties, corrosion resistance, aging resistance and fire-retardant performance.

The application belongs to the technical field of polyurethane elastomer preparation, and discloses a water-resistant and self-repairing polyurethane elastomer, a preparation method thereof and application of the polyurethane elastomer in a humidity sensor. The method comprises the following steps: S1, dissolving 4,4'-diaminodiphenyl methane and p-hydroxybenzaldehyde in anhydrous ethanol to generate a small molecule MDOH with an imine bond structure through Schiff base reaction, and the small molecule MDOH is used as a chain extender of polyurethane; S2, reacting hydroxyl-terminated polybutadiene and isophorone diisocyanate at 60 DEG C to generate a prepolymer, and adding MDOH and glycerol monostearate into the obtained prepolymer to extend the chain; the introduction of MDOH can make the material have excellent self-repairing capability, and the glycerol monostearate is beneficial to further improve the self-repairing capability and water resistance. In addition, the humidity sensor based on the polyurethane elastomer can exhibit good sensing performance.

The invention relates to the technical field of high-performance coatings, and discloses a wear-resistant coating, a preparation method and application of the wear-resistant coating to an alumite color layer. The preparation method of the wear-resistant coating comprises the following steps: reacting 1, 6-dibromohexane with p-hydroxybenzaldehyde to obtain an intermediate product A; reacting the intermediate product A with p-phenylenediamine to obtain an intermediate product B; modifying the surface modified silicon carbide / silicon dioxide composite material with the intermediate product B to obtain an organic-inorganic hybrid filler; treating the organic-inorganic hybrid filler with N-methyldiethanolamine to obtain a modified organic-inorganic hybrid filler; the preparation method comprises the following steps: preparing a waterborne polyurethane acrylate emulsion by taking a multifunctional modifier, a modified organic-inorganic hybrid filler and tetrakis (3-mercaptopropionic acid) pentaerythritol ester as raw materials; and mixing the waterborne polyurethane acrylate emulsion with other auxiliaries to obtain the wear-resistant coating. The wear-resistant coating provided by the invention has good mechanical properties, wear resistance, heat resistance and antibacterial properties, and can be used in an alumite color layer.

The invention discloses a 2-hydroxy-3-pinonyl difluoro borane complex ratio type fluorescent probe for detecting H2O2 as well as a preparation method and application of the 2-hydroxy-3-pinonyl difluoro borane complex ratio type fluorescent probe. The preparation method comprises the following steps: by taking 2-hydroxy-3-pinone as a raw material, carrying out aldol condensation reaction on the 2-hydroxy-3-pinone and p-hydroxybenzaldehyde to prepare a compound DP; the compound DP and boron trifluoride diethyl etherate are subjected to a complexation reaction, and a compound DPO is prepared; the compound DPO and 4-bromomethyl phenylboronic acid pinacol ester are subjected to an etherification reaction, and the fluorescent probe DPBO is prepared. The probe DPBO can specifically recognize H2O2, under irradiation of 385nm ultraviolet light, after H2O2 is added into a DMSO / PBS solution of the probe DPBO, the fluorescence color of the solution gradually changes from blue-green to yellow, and the lowest detection limit is 0.09 [mu] M. The probe has the advantages of being simple and convenient to synthesize, good in selectivity, high in sensitivity, good in biocompatibility, low in toxicity and the like, and has a good application prospect.

The invention relates to the technical field of industrial wastewater treatment, and discloses a modified attapulgite adsorbent for treating p-hydroxybenzaldehyde wastewater and a use method thereof.The adsorbent is prepared by treating an attapulgite raw material with a modifier, the modifier is a surfactant or a silane coupling agent, and the modifier is a modified attapulgite adsorbent. The attapulgite raw material is selected from at least one of attapulgite activated clay, attapulgite filter cakes, attapulgite raw ore and attapulgite extraction leftover materials, the surfactant is a quaternary ammonium salt type cationic surfactant, specifically, hexadecyl trimethyl ammonium bromide, and the concentration of a surfactant aqueous solution used in the modification process is 0.05-0.2 mol / L. The attapulgite raw material is modified by adopting a single surfactant or a silane coupling agent, a complex multi-step composite modification route in the prior art is abandoned, and the modification process is simplified and easy to operate; the attapulgite raw material is wide in selectable range, and related byproducts or leftover materials of mineral resources can be fully utilized, so that comprehensive utilization of the resources is realized, and the cost of the raw materials is reduced.

This invention relates to a strain of *Pseudomonas proteus* PHBA133 and its applications, belonging to the field of bioengineering. The strain, classified as *Pseudomonas proteus* coglossicida PHBA133, was deposited at the China General Microbiological Culture Collection Center on December 26, 2022, with accession number CGMCC No. 26275. The *Pseudomonas proteus* PHBA133 provided by this invention exhibits strong genetic stability and a broad substrate spectrum. It can ferment and convert p-hydroxycinnamic acid and its derivatives into corresponding aldehydes, with a conversion concentration of p-hydroxybenzaldehyde as high as 3.4 g / L, demonstrating potential for industrial application. The production process is simple, mild, green, and safe, avoiding the problems of long reaction times, high energy consumption, and environmental pollution faced by traditional chemical methods. Furthermore, it produces fewer byproducts, facilitating extraction and separation operations.

The invention provides a method for preparing p-hydroxystyrene, which comprises the following steps: reacting a raw material p-hydroxybenzaldehyde with a raw material dimethylacetamide in an organic solvent in a reactor under the catalysis of a basic catalyst to generate p-hydroxystyrene, wherein the method does not include reacting p-hydroxybenzaldehyde with malonic acid to produce p-hydroxystyrene.

The invention discloses an improved TR beta selective thyroid hormone GC-1 preparation method, and relates to the field of pharmaceuticals, p-hydroxybenzaldehyde and 3, 5-dimethyl-4-bromophenol are used as starting raw materials, and the TR beta selective thyroid hormone GC-1 is obtained through eight-step reactions of Friedel-Crafts alkylation, phenolic hydroxyl group protection, aldehyde addition reaction, alcoholic hydroxyl group protection, selective deprotection, phenol alkylation, acid catalytic hydrogenation and the like. The Sobetirome is synthesized by the method with the total yield of 54%. Compared with the prior art, the method has the advantages that a protecting group is easy to remove, the product stability is improved, and the yield is high.

The invention provides a method for preparing p-hydroxystyrene, which comprises the following steps: reacting a raw material p-hydroxybenzaldehyde with a raw material dimethylacetamide in an organic solvent in a reactor under the catalysis of a basic catalyst to generate p-hydroxystyrene, wherein the method does not include reacting p-hydroxybenzaldehyde with malonic acid to produce p-hydroxystyrene.

The invention relates to the technical field of electronic products, in particular to a prepreg for an electronic product shell and a preparation method of the prepreg. Glass fiber cloth is subjected to plasma treatment and phosphorus-containing polysiloxane precursor liquid treatment; carrying out phenol amine modification on the heat-conducting filler, and then grafting an aldehyde benzophenone derivative to obtain a composite heat-conducting filler; mixing epoxy resin, the composite heat-conducting filler, a curing agent, an auxiliary agent and a solvent to obtain an epoxy dipping solution; coating the modified glass fiber cloth with the epoxy dipping liquid to obtain a prepreg; the preparation method comprises the following steps: by taking titanium dioxide modified hexagonal boron nitride as a heat-conducting filler, co-depositing catechol and polyethyleneimine on the surface of the heat-conducting filler, and then grafting an aldehyde benzophenone derivative prepared from p-hydroxybenzaldehyde, isophorone diisocyanate and 2-aminobenzophenone as raw materials by utilizing a Schiff base reaction, so as to prepare the heat-conducting material. The prepreg is endowed with long-term aging resistance and corrosion resistance, and the service life of the prepreg is prolonged.

The invention provides a method for synthesizing synephrine through multi-enzyme cascade catalysis, and belongs to the technical field of biology. According to the invention, a multi-enzyme cascade production process from p-hydroxybenzaldehyde to synephrine is systematically carried out for the first time. According to the method provided by the invention, cheap raw materials p-hydroxybenzaldehyde and glycine are taken as substrates, and under the action of L-threonine aldolase, tyrosine decarboxylase and methyltransferase, synephrine is generated through condensation reaction, decarboxylation reaction and methylation reaction. The method provided by the invention has the advantages of easily available raw materials, mild reaction conditions, simple and controllable process and excellent industrial production prospect.

The application relates to application of p-hydroxybenzaldehyde A in preparation of blood sugar reducing drugs. The p-hydroxybenzaldehyde A is prepared by adopting the methods of ethanol immersion, organic solvent extraction, chromatography and high performance liquid chromatography and the like with acid fruit as raw material. Further research finds that the compound has the effect of reducing blood sugar and can be used for treating diabetes.

The invention discloses a viscosity fluorescent probe, a synthesis method thereof, a viscosity detection method, application and a viscosity detection reagent, and belongs to the technical field of viscosity detection. The structural formula of the viscosity fluorescent probe is as shown in formula 1. The preparation method comprises the following steps: dissolving 1-ethyl-2-methylquinoline-1-onium iodide and malononitrile in absolute ethyl alcohol, stirring in an ice bath, then adding sodium tert-butoxide for reaction, and carrying out reduced pressure suction filtration to obtain a yellow solid; dissolving the yellow solid and p-hydroxybenzaldehyde in methanol, adding piperidine, stirring and refluxing, and cooling to room temperature after the reaction is finished; finally, the mixture obtained through the reaction is subjected to suction filtration to obtain the viscosity fluorescent probe, the probe can detect the viscosity in a high-selectivity and high-sensitivity mode, the fluorescence probe can avoid biological autofluorescence interference due to the light absorption and fluorescence emission characteristics of the fluorescence probe, and therefore the fluorescence probe can be applied to viscosity detection of food, beverages and the like.

The invention provides a synthesis method of salbutamol, which takes p-hydroxy benzaldehyde as an initial raw material, and salbutamol is obtained through multi-step reaction. The synthesis route is simple, the cost is low, the yield and the purity are high, aftertreatment is simple, and the method is suitable for industrial production.

The application belongs to the technical field of electrocatalysis, and specifically discloses an electrochemical detection method for p-hydroxybenzaldehyde (PHBA), which comprises the following steps: placing a modified manganese tetroxide modified glassy carbon electrode as a working electrode, a calomel electrode as a reference electrode and a platinum sheet electrode as an auxiliary electrode in a to-be-detected solution; obtaining a characteristic peak current value of the to-be-detected solution by using a differential pulse voltammetry method; and obtaining the content of the p-hydroxybenzaldehyde in the to-be-detected solution according to a linear relationship curve through the characteristic peak current value. The method provided by the application can accurately and efficiently detect the content of the p-hydroxybenzaldehyde in various to-be-detected samples, and has a wide linear range, a low detection limit and good anti-interference performance. The method has the advantages of high sensitivity and simple operation, and is suitable for analysis and detection in the fields of chemical industry, medicine and environment.

The invention relates to the technical field of photosensitive polymer synthesis, in particular to a photosensitive polyurethane elastomer based on a [2 + 2] optical cyclization mechanism and a preparation method and application thereof. The preparation method comprises the following steps: reacting p-hydroxybenzaldehyde, a compound M, ammonium acetate and a substance capable of accepting foreign electron pairs in a first polar solvent to obtain a photosensitive monomer PD-DHP; dissolving a polymer, diisocyanate, a chain extender and a catalyst in a second polar solvent, and reacting to obtain an intermediate solution; and adding a photosensitive monomer PD-DHP into the intermediate solution, and reacting to obtain the photosensitive polyurethane elastomer. The photosensitive polyurethane elastomer is based on a chemically crosslinked [2 + 2] optical cyclization reaction mechanism, a cage-shaped three-dimensional structure is photochemically formed by a two-molecule pyridine structure, diffusion of monomers in a polymer can be avoided, and the photosensitive polyurethane elastomer has good film-forming property; and moreover, the crosslinking density of a polymer molecular chain can be enhanced, and the stability of the embossment structure on the surface of the polymer is improved, so that the anti-counterfeiting encryption effect is excellent.

The present invention relates to the technical field of chemical engineering, and particularly relates to a method for preparing p-methoxybenzaldehyde. The method uses p-hydroxybenzaldehyde and dimethyl carbonate as starting materials, and prepares p-methoxybenzaldehyde by means of a methylation reaction using dimethyl carbonate in the presence of a solvent and a basic catalyst. The methylation reaction of dimethyl carbonate is carried out at a temperature of 150 °C to 160 °C in an autoclave. In the present application, the methylation reaction using dimethyl carbonate is controlled at a high temperature (150 °C to 160 °C) and is carried out in an autoclave, such that dimethyl carbonate can be mainly present in a liquid state in the reaction system at a temperature far exceeding the boiling point, thereby promoting the methylation reaction of dimethyl carbonate, and improving the purity of the prepared p-methoxybenzaldehyde final product, the yield, and the energy-efficiency.

The invention provides a method for preparing p-hydroxystyrene, which comprises the following steps: reacting a raw material p-hydroxybenzaldehyde with a raw material dimethylacetamide in an organic solvent in a reactor under the catalysis of a basic catalyst to generate p-hydroxystyrene, wherein the method does not include reacting p-hydroxybenzaldehyde with malonic acid to produce p-hydroxystyrene.

The application discloses a preparation method of a benzaldehyde modified oligosaccharide self-assembly material. The method is that an oligosaccharide is subjected to etherification reaction with p-hydroxybenzaldehyde to obtain a benzaldehyde modified oligosaccharide etherification product, and then the product is dissolved in an aqueous solution to form a self-assembly system. The self-assembly system formed by the benzaldehyde modified oligosaccharide etherification product in the aqueous solution comprises micelles with a size of 20-100 nm and vesicles with a size of 100-1000 nm. The self-assembly system can be used in the field of drug delivery in the biomedical field.

The invention discloses a high-wear-resistance polyether-ether-ketone composite material and a production process thereof, and relates to the technical field of composite materials. The high-wear-resistance polyether-ether-ketone composite material prepared by the invention is prepared by compounding polyether-ether-ketone, hyperbranched polyimide and modified carbon nanotubes, and the hyperbranched polyimide is prepared by reacting pyromellitic dianhydride, 4, 4 '-diaminodiphenyl ether and a hyperbranched hydroxyl prepolymer. The hyperbranched hydroxyl prepolymer is prepared by reaction of polyhydroxypyridine and hydroxyl-terminated hyperbranched poly (amine-ester), the polyhydroxypyridine is prepared by reaction of p-hydroxyacetophenone and p-hydroxybenzaldehyde, and the modified carbon nanotubes are prepared by reaction of carboxylated carbon nanotubes and pyridine derivatives. The pyridine derivative is prepared from trifluoromethylthio pyridine and 4-piperidine sulfonyl aniline through a reaction, the trifluoromethylthio pyridine is prepared from 2, 6-dichloro-4-trifluoromethylpyridine and 4-(trifluoromethylthio) phenylboronic acid through a reaction, and the prepared composite material has excellent thermal stability, wear resistance and flame retardance.

The invention provides a method for synthesizing p-hydroxybenzaldehyde from p-hydroxybenzoic acid through light-driven enzyme catalysis. A used reaction system comprises carboxylic acid reductase (CAR), a photosynthesis unit, ferredoxin (Fdx) and phosphotransferase (PAP). According to the method, light energy is utilized to drive spinach capsule membranes to co-regenerate NADPH and ATP, and the problem that carboxylic acid reductase needs coenzyme supply of NADPH and ATP at the same time is solved. According to the method, a light energy driven enzyme catalysis method is adopted, a biological photosynthetic reaction is used for replacing a traditional high-energy-consumption and high-pollution chemical process, and green and efficient synthesis of p-hydroxybenzaldehyde is achieved through cooperation of double-coenzyme light regeneration and enzyme specific catalysis.

The invention discloses a method for synthesizing gastrodin by catalyzing phenol through a multi-enzyme cascade system. The multi-enzyme cascade system comprises carboxylase, carboxylic acid reductase, alcohol dehydrogenase, glucose dehydrogenase, phosphokinase and glycosyl transferase. Phenol is used as a starting raw material and is converted into a key intermediate p-hydroxybenzoic acid through catalysis of carboxylase, the p-hydroxybenzoic acid is reduced into p-hydroxybenzaldehyde through carboxylic acid reductase, then the p-hydroxybenzaldehyde is reduced into p-hydroxybenzyl alcohol through alcohol dehydrogenase, and finally gastrodin is synthesized through catalysis of glycosyl transferase. According to the method, one-pot reaction is adopted, in-situ regeneration of coenzyme NAD (P) H and ATP is achieved through glucose dehydrogenase and phosphokinase, reaction conditions are mild, selectivity is high, environment friendliness is achieved, and a new way is provided for sustainable production of phenolic glycoside compounds.

This application discloses a novel organosilicon-polyphosphazene flame retardant with high thermal stability, its preparation method, and its application. The preparation method involves first reacting hexachlorocyclotriphosphazene with p-hydroxybenzaldehyde under catalysis to obtain hexa-p-aldehyde-phenoxycyclotriphosphazene, and then reacting it with poly(dimethylsiloxane), bis(3-aminopropyl)-terminated poly(dimethylsiloxane), under heating conditions to obtain the organosilicon-polyphosphazene flame retardant. This application introduces a siloxane structure into the flame-retardant hexa-p-aldehyde-phenoxycyclotriphosphazene, resulting in a flame retardant with good thermal stability, high flame retardant efficiency, and ease of addition. Furthermore, the preparation method is simple, the conditions are easy to control, and the reproducibility is good. The obtained flame retardant can be applied to epoxy resins.