116 results about "Aniline hydrochloride" patented technology

The invention discloses a method for synthesizing a 4-chloro-2-(trifluoroacetyl)aniline hydrochloride hydrate intermediate, which belongs to the technical field of compound preparation methods. The method comprises the following steps of: 1) reacting parachloroaniline with acyl chloride in the presence of a methylbenzene solvent to obtain an intermediate (II); 2) dissolving the intermediate (II) in organic solvent to obtain solution, introducing trifluoro-acetyl chloride into a flask which is filled with the mixed liquor of the organic solvent and lewis acid and slowly filling the solution ofthe intermediate (II) into the flask dropwise to perform a Friedel-Crafts reaction to obtain an acylate intermediate (III), wherein a charging molar ratio of the trifluoro-acetyl chloride to the intermediate (II) is 1: 1; and 3) hydrolyzing the intermediate (II) to remove protective groups to form a salt under acid condition to obtain the 4-chloro-2-(trifluoroacetyl)aniline hydrochloride hydrate intermediate(IV). The method has the advantages of high safety, low cost, simple operation, less pollution, total yield of over 78.1 percent and content of more than or equal to 99.0 percent.

The present invention relates to process of preparing 4, 4'-diamido-4''-hydroxy triphenyl methane. The process includes the following steps: 1. reaction of aniline and hydrochloric acid solution in the molar ratio of 1.0 to 1.0-1.5 at room temperature for 0.1-4 hr, adding water insoluble organic solvent, heating reflux to separate out water, cooling, filtering and drying to obtain aniline hydrochloride; and 2. reaction of p-hydroxybenzaldehyde and aniline in the molar ratio of 1.0 to 2.0-4.0 in nitrogen with aniline hydrochloride as catalyst at 80-120 for 1-8 hr, cooling, vacuumizing, eliminating excessive aniline, adding alcohol solvent, heating to dissolve, cooling to crystallize, filtering and drying to obtain purple needle-shaped 4, 4'-diamido-4''-hydroxy triphenyl methane crystal. The present invention has simple operation, low cost and high product purity, and is suitable for industrial production.

The present invention relates to chemical and metallurgical technology, and is especially process of preparing anhydrous magnesium chloride through dewatering bischofite. The process includes the first reaction of aniline hydrochloride and bischofite to produce aniline hydrochloride-magnesium chloride hexahydrate complex salt, the subsequent spray drying and pelletizing the complex salt, and final eliminating crystallized water and aniline hydrochloride in a fluidized bed to obtain the anhydrous magnesium chloride product. The present invention has the advantages of low power consumption, simple technological process, easy industrial amplification, environment friendship, stable product quality, etc.

The invention relates to a preparation method of diphenylmethane series diamine and polyamine with low macromolecular impurity content. According to the method, the content ratio of monomer formaldehyde in formaldehyde is controlled in 40-60wt% before aniline and the formaldehyde are reacted under the condition of an acid catalyst. Before the formaldehyde and the aniline or aniline hydrochloride are mixed, a state of formaldehyde water solution is changed, low-polymerized formaldehyde in water solution is depolymerized, the content of the monomer formaldehyde in the water solution is controlled to reach a more favorable range, macromolecular resin solid impurities generated in condensation reaction are decreased, blocking caused by aggregation of macromolecular polymers in a device and a pipeline is remarkable relieved in medium and long term continuous production processes of DAM is obviously relieved, and the content of macromolecular impurities in the DAM is decreased.

The inventiondiscloses a preparation method of ticagrelor. The method comprises the following steps: (1) reducing a compound shown in a formula III in the presence of a proton source provided by sodium borohydride or potassium borohydride and diethyl aniline hydrochloride to obtain a compound shown in a formula IV; (2) reacting the compound IV in the presence of alkali to generate a compound VI; (3) hydrolyzing the compound VI without purification to generate a compound VII; (4) reacting the compound VII to generate acyl chloride, reacting the acyl chloride to generate formamide, thus obtaining a compound shown in a formula IX; and (5) carrying out Hofmann rearrangement on the compound IX to obtain a compound shown in a formula II. Regents used in the method are nontoxic, harmless, environmentally friendly and low in price; the used key reagents can be recycled. Therefore, the method is applicable to industrial production.

The invention belongs to the technical field of oil water separation, and provides a PMIA super-hydrophobic nano-fiber membrane for oil water separation and a preparation method thereof. The method comprises the following steps: pretreating a PMIA nano-fiber membrane prepared by electrostatic spinning; spraying and depositing aniline hydrochloride and titanium dioxide mixed solution to the surfaceof the fiber membrane; performing ultraviolet radiation, and polymerizing to generate polyaniline nano-particles; loading to the surface of the fiber membrane, and further performing surface etchingto prepare the PMIA super-hydrophobic nano-fiber membrane for oil water separation. Compared with the prior art, the PMIA super-hydrophobic nano-fiber membrane has excellent super-hydrophobic performance and high oil-water separation efficiency, has good mechanical performance, heat resistance and corrosion resistance, and good durability; and the preparation process is simple and environment-friendly, and can be widely applied to the field of oil water separation.

The invention discloses a preparation method of polyaniline composite long-acting conductive polyester fiber, and belongs to the technical field of textile materials. The method comprises the following steps of: firstly, carrying out ultrasonic impregnation on the polyester fiber by using alkali liquor, and then carrying out oxygen plasma treatment to obtain pretreated polyester fiber; dispersingnano graphene oxide in water, and modifying the nano graphene oxide under the action of sodium polystyrene sulfonate to prepare modified graphene oxide dispersion liquid; dispersing aniline hydrochloride and the pretreated polyester fiber in modified graphene oxide dispersion liquid, performing ultrasonic impregnation, adding an initiator under a constant-temperature stirring state, performing polymerization reaction, filtering, washing and drying to obtain composite fibers, sequentially washing the composite fibers with hydrochloric acid, acetone and deionized water, mixing with a dehydratingagent, performing reduced-pressure heating reaction, washing with water, and performing vacuum drying to obtain the polyaniline composite long-acting conductive fiber. The polyaniline composite long-acting conductive polyester fiber has excellent conductive performance and conductive long-acting performance.

The invention discloses a preparation method of a 4-chloro-2-(trifluoroacetyl) aniline hydrochloride hydrate and belongs to the field of compound synthesis. The method adopts parachloroaniline as a raw material and comprises steps as follows: 1, parachloroaniline is subjected to a reaction with pivaloyl chloride, and 4-chloro-N-pivaloyl aniline is obtained; 2, 4-chloro-N-pivaloyl aniline is subjected to a reaction with ethyl trifluoroacetate under the action of n-butyllithium, and N-(4-chloro-2-trifluoroacetyl phenyl) pivaloyl amide is obtained; 3, N-(4-chloro-2-trifluoroacetyl phenyl) pivaloyl amide is subjected to a reaction with acid, pivaloyl is removed, and meanwhile, the 4-chloro-2-(trifluoroacetyl) aniline hydrochloride hydrate is obtained. The operation is simple, discharge of three wastes is greatly reduced, the treatment difficulty of the three wastes is reduced, the cost is low, the total recovery is up to 86.7%, and the preparation method of the 4-chloro-2-(trifluoroacetyl) aniline hydrochloride hydrate is suitable for industrial production.

The invention discloses high-activity rosin soldering flux. The high-activity rosin soldering flux is prepared from the following raw materials in parts by weight: 20-30 parts of rosin, 10-15 parts of phenolic resin, 5-10 parts of lactic acid, 5-10 parts of salicylic acid, 2-5 parts of citric acid, 2-3 parts of malonic acid, 10-15 parts of stearic acid, 5-10 parts of octaphenyl polyoxyethyiene, 2-5 parts of lauryl sodium sulfate, 0.5-1 part of aniline hydrochloride, 0.5-1.5 parts of zinc chloride, 1-1.5 parts of tin chloride, 0.2-0.5 part of aluminum chloride, 0.5-1 part of catechol, 1-3 parts of mercaptobenzothiazole, 5-10 parts of water, 2-5 parts of alcohol and 3-4 parts of acetone. The high-activity rosin soldering flux disclosed by the invention is not only environment-friendly in a using process, but also capable of improving the welding effect to the greatest extent.

The invention discloses a one-step synthetic process of a rubber antioxidant RD. The process is as below: using aniline and acetone as raw materials for reaction and hydrochloric acid as a catalyst; reacting aniline with hydrochloric acid in a reaction kettle with a stirrer for synthesis of aniline hydrochloride; conducting condensation reaction on the aniline hydrochloride with an excessive amount of acetone in the reaction kettle with stirrer to generate a polymer; neutralizing hydrochloric acid in the reaction process with sodium hydroxide; recovering acetone and aniline from the water phase in a waste water tower; clarifying the oil phase, conducting continuous dehydration in a flash tank, and steaming to remove aniline; and sending the condensation polymer with aniline removed into a finished product distillation tower for removing a front cut fraction, so as to finally obtain the product of antioxidant RD. Compared with a traditional one-step method, the improved one-step method can timely deprive unreacted raw materials, so that the content of active ingredients (dimer, trimer and tetramer) substantially increases.

The invention relates to a preparation method of 3-(phenyl amino) propyl alkoxy silane, and recycling technology of a by-product, belonging to the technical field of organic chemistry. The preparation method comprises the steps of: using aniline and 3-chlorine propyl alkoxy silane for carrying out ammonolysis reaction to generate the solid of 3-(phenyl amino) propyl alkoxy silane and aniline hydrochloride; filtering the aniline hydrochloride; and distilling filtrate to obtain the 3-(phenyl amino) propyl alkoxy silane product, wherein the 3-(phenyl amino) propyl alkoxy silane product contains phenyl, amino, alkoxy or methyl, can provide and improve special functional properties for polyurethane material, adhesive, and reinforced phenolic composite material. The invention can be used for neutralizing treatment of the by-product aniline hydrochloride, so that the environmental pollution can be avoided, and the industrial wastewater directly enters a sewage treatment system; furthermore, aniline can be recovered and recycled, so that the production cost is reduced.

The preparation process of 4, 4'-methylene-bis-(3-chloro-2, 6-diehtyl aniline) (MCDEA) belongs to the field of polymer synthesis technology. Under the protection of inert gas, material 3-chloro-2, 6-diehtyl aniline is reacted with hydrochloric acid in water solution to produce 3-chloro-2, 6-diehtyl aniline hydrochloride. Then, water solution of formaldehyde is dropped while heating to produce condensation; and through maintaining the temperature for finishing the reaction and neutralization with alkali, coarse MCDEA product is separated. Through further decolorizing, dewatering, crystallizing and pelletizing, MCDEA product is obtained. The preparation process is simple and has mild reaction condition, low production cost and high yield, and MCDEA has micro toxicity and may be used to replace MOCA as chain expander for PU material.

The invention discloses a graphene oxide hybrid polyaniline-based flexible electrode material and a preparation method and application thereof, and relates to the field of flexible electronic materials. The preparation method comprises the following main preparation steps: (1) preparing a graphene oxide (GO) dispersion liquid; (2) preparing graphene oxide/polyacrylamide matrix hydrogel (GMH); (3)soaking the hydrogel obtained in the step (2) in an aniline hydrochloride solution; and (4) sequentially adding phytic acid and ammonium persulfate into the solution to carry out in-situ polymerization, and performing washing to remove impurities, thereby obtaining the graphene oxide hybrid polyaniline-based flexible electrode material. According to the preparation method disclosed by the invention, the mechanical property of the material is effectively improved, a polyaniline conductive network is perfected, and the prepared flexible electrode material has high stretchability and excellent electrochemical performance, can be widely applied to energy storage devices such as supercapacitors and the like, and has a wide application prospect in the field of flexible electronics.

The invention discloses an aniline black pigment producing method. The aniline black pigment producing method comprises the following steps of: taking aniline as a raw material, and adding hydrochloric acid to synthesize an aniline hydrochloride solution; adding a hydroxyl copper phosphate catalyst, and dripping hydrogen peroxide; and after reaction, filtering, cleaning, drying and grinding to obtain aniline black pigment. In the aniline black pigment producing method, dichromate is not taken as an oxidant, thus avoiding chromium pollution; the hydroxyl copper phosphate catalyst coordinates with the hydrogen peroxide oxidant, thus improving the yield of the aniline black pigment; the produced obtained aniline black pigment is pure in color and luster and is blue phase black; and the production is simple and convenient.

The invention relates to composite material and a preparation method of the composite materials, in particular to core-shell nano-copper nickel solid solution/polyaniline composite materials and a preparation method of the core-shell nano-copper nickel solid solution/polyaniline composite materials. The core-shell nano-copper nickel solid solution/polyaniline composite materials and the preparation method mainly solve the problems that an existing preparation process is complex, high in cost, long in preparation time and unstable in chemical property of obtained composite materials. The core-shell nano-copper nickel solid solution/polyaniline composite materials comprise the aqueous solution of aniline hydrochloride, solid solution microemulsion, APS solutions and acetone. The preparation method comprises the first step that copper nickel solid solution powder is prepared, the second step that the solid solution microemulsion is prepared through the prepared copper nickel solid solution powder, methylbenzene and SDBS, the third step that the aqueous solution of the aniline hydrochloride and the solid solution microemulsion are blended, the APS solutions are dropwise added, after stirring and reactions, the acetone is added to be stirred, then standing, suction filtration, washing and vacuum drying are carried out, and then the core-shell nano-copper nickel solid solution/polyaniline composite materials are obtained. The core-shell nano-copper nickel solid solution/polyaniline composite materials and the preparation method of the core-shell nano-copper nickel solid solution/polyaniline composite materials are applied to the field of preparing conducting materials, capacitors and electrochromic materials.

The invention discloses a preparation method of 9,9-bis(4-aminophenyl)fluorene, which comprises the following steps: under the protection of inert gas, adding fluorenone, aniline hydrochloride and aniline used as raw materials, methyl benzene used as a solvent and sodium bisulfite used as a catalyst into a reaction device with a water separator; heating up to 110-130 DEG C while stirring, reacting for 20-40 minutes, and then separating out a liquid generated in the water separator; continuing to react at this temperature for 2-4 hours, and then separating out water generated in the water separator; slowly heating up to 130-140 DEG C, reacting at this temperature for 1-2 hours, and stopping the reaction when no water is generated in the water separator; and carrying out post treatment to obtain the 9,9-bis(4-aminophenyl)fluorene. The method has the advantages of moderate conditions and high yield, and is suitable for industrial large-scale production.

The invention aims to provide a pretreatment reagent for living body transportation of parents of cephalopods. The pretreatment reagent can improve the effect of living body transportation of parents of cephalopods and has the advantages of simple operation method, low cost, good anesthetic effect, low action concentration, controllable resuscitation time, stable performance and low damage to fish body. According to the invention, aniline hydrochloride acetyl propyl aminobenzoate, a derivative of anthranilic acid, is used as main active component of anesthetic used in pretreatment during the process of living body transportation, which has good anesthetic effect on cephalopods, low action concentration, controllable resuscitation time and stable performance. In addition, after combined use with CaCl2, the anesthetic effect of aniline hydrochloride acetyl propyl aminobenzoate at low-temperature is basically not reduced.

The invention provides a synthetic method of an efavirenz key intermediate. The synthetic method comprises the following steps: carrying out reaction on parachloroaniline and pivaloyl chloride to protect amino to obtain N-(4-chlorphenyl)-2,2-dimethyl propanamide; carrying out Friedel-Crafts acylation reaction on the product and Friedel-Crafts acylation under action of aluminum trichloride to hydrolyze to obtain 4-chloro-2-trifluoroacetyl aniline hydrochloride in an acidic condition; and then carrying out alkalization to obtain 4-chloro-2-trifluoroacetyl aniline, carrying out reaction with cyclopropyl acetylene magnesium chloride in a catalytic system formed by a ligand (1R, 2S)-1-phenyl-2-(1-pyrrolidyl)-1-propyl alcohol, and carrying out an asymmetrical self-catalytic reaction to obtain the efavirenz key intermediate. The synthetic method of the efavirenz key intermediate, provided by the invention, is cheap and easily available in raw material, low in toxicity of reagent and mild in reaction condition, amino protection and deprotection are not carried out frequently, the line is concise, the yields of reaction of each step are excellent, and the total yield is high.