3 results about "Benzbromarone" patented technology

The invention discloses a pharmaceutical composition of benzbromarone and a preparation method thereof, and by optimizing prescription components and a process of a benzbromarone pharmaceutical oral preparation, the provided pharmaceutical composition of benzbromarone or salts thereof is pure white in color, complete and bright in surface and good in dissolution performance. The preparation method of the pharmaceutical composition of the benzbromarone or the salt thereof is simple and convenient, an organic solution containing the benzbromarone or the salt thereof does not need to be prepared, the risk of organic solvent residue does not exist, the granulation process window is large, and industrial production is easy; the particles obtained by the process are uniform, compact and good in flowability; the tablets obtained by the process are pure white in color, complete and bright in surface, small in weight difference and good in dissolution performance.

Described herein are methods for treating or preventing gout or hyperuricemia comprising the administration (3,5-dibromo-4-hydroxyphenyl)(2-(1-hydroxyethyl)benzofuran-3-yl-4,5,6,7-d 4)methanone, and solvates thereof.

To provide an ATP production promoter useful for preventing or treating diseases associated with decreased ATP production, particularly renal impairment. [Solution] The present invention comprises an ATP production promoter containing a component having URAT1 inhibitory activity. Preferably, the component having URAT1 inhibitory activity is at least one selected from the group consisting of benzbromarone, probenecid, dotinurad, recinurad, and berinurad. The present invention is expected to be useful as a preventive and therapeutic agent for diseases of decreased ATP production, and is particularly useful as a therapeutic and / or preventive agent for nephrotic syndrome, chronic glomerulonephritis, chronic tubulointerstitial nephritis, chronic pyelonephritis, amyloid kidney, familial juvenile hyperuricemia nephropathy, autosomal dominant tubulointerstitial kidney disease, nephronoplasia, renovascular hypertension, renal vein thrombosis, renal arteriovenous fistula, renal tubular acidosis, Gitelman syndrome, Bartter syndrome, Fanconi syndrome, Lowe syndrome, Alport syndrome, kidney and ureteral stones, and chronic renal failure.