A new type of imidazo[2,1-b][1,2,4]triazole-benzene ring tandem fluorescent compound and its application
By developing a new imidazolo[2,1-b][1,2,4] triazole-benzene ring tandem fluorescent compound, the problem of limited feasibility of existing fluorescence technologies in specific applications is solved, and efficient bioimaging and cell imaging is achieved, which has important diagnostic and therapeutic significance.
Patent Information
- Application Number
- CN202310009258.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2023-01-04
- Publication Date
- 2025-04-04
- Estimated Expiration
- 2043-01-04
AI Technical Summary
The feasibility of existing fluorescence technologies in specific applications is limited by the availability of fluorescent molecules, making it difficult to quickly track targets in complex biological systems, affecting the efficiency of disease diagnosis and treatment.
A new class of imidazolo[2,1-b][1,2,4] triazole-benzene ring tandem fluorescent compounds were developed and applied to the development of fluorescent probes and bioimaging technologies. This compound has good fluorescence function and active group salicylic acid structure, and can have certain applications in the biological field.
This fluorescent compound has excellent fluorescence performance, with a maximum excitation wavelength range of 306-350nm, a maximum absorption wavelength range of 386-566nm, a fluorescent quantum yield of up to 0.86, and is basically non-cytotoxic. It is suitable for cell imaging and the diagnosis and treatment of malignant diseases.