A strain of Bacillus albus GXU-2 and a method for producing γ-polyglutamic acid using the same

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By optimizing the seed culture and fermentation culture conditions of Bacillus albicans GXU-2, the problem of low γ-polyglutamate fermentation yield was solved, high yield and simplified process were achieved, and industrial production potential was achieved.

CN116064315BActive Publication Date: 2025-03-28GUANGXI UNIV +1

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Patent Information

Application Number: CN202211367797.X
Authority / Receiving Office: CN · China
Patent Type: Patents(China)
Current Assignee / Owner
Filing Date: 2022-11-03
Publication Date: 2025-03-28
Estimated Expiration: 2042-11-03

Application Information

Patent Timeline

03 Nov 2022

Application

CN202211367797.X

28 Mar 2025

Publication

CN116064315B

IPC: C12N1/20; C12P13/02; C12R1/07

CPC: C12N1/205; C12N1/20; C12P13/02; C12R2001/07

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Application Domain

Bacteria Microorganism based processes

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AI Technical Summary

Technical Problem

In the prior art, the fermentation yield of γ-polyglutamic acid is relatively low and it is difficult to meet the demand for large-scale production.

Method used

Bacillus albicans GXU-2 was used to optimize seed culture and fermentation culture conditions, including appropriate temperature, pH, ventilation volume and stirring speed, to achieve high yield of γ-polyglutamic acid.

Benefits of technology

The production of γ-polyglutamic acid has been achieved above 70g/L, simplified the fermentation process, reduced costs, and has the potential for large-scale industrial production.

✦ Generated by Eureka AI based on patent content.

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Abstract

The present invention belongs to the technical field of microbial fermentation, and specifically relates to a strain of Bacillus albus GXU-2 and a method for producing γ-polyglutamic acid using the strain. The present invention provides a strain of Bacillus albus GXU-2 (Bacillus albus) GXU-2, which has been biologically preserved and has a preservation number of CGMCC No. 24579. The Bacillus albus GXU-2 provided by the present invention can be fermented to produce high γ-polyglutamic acid, with an output of more than 70 g / L, thereby providing a new method for the biosynthesis of γ-polyglutamic acid.

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