A fermented medicine prepared by lactobacillus fermentation of traditional Chinese medicine, and its preparation method and application

Through the method of Lactobacillus fermenting snake beds and squids, a new therapeutic drug was developed, which solved the problem of poor drug resistance and mucosal repair effects in long-term use of existing drugs, and achieved strong antibacterial, mucosal repair and microenvironment improvement effects.

CN116509912BActive Publication Date: 2025-03-25WEIFANG MEDICAL UNIV
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Patent Information

Application Number
CN202211703013.6
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2022-12-29
Publication Date
2025-03-25
Estimated Expiration
2042-12-29

AI Technical Summary

Technical Problem

The long-term use of existing drugs for treating candidiasis vulvaginal diseases will increase drug resistance and will not be effective in repairing vaginal mucosal damage and improving the vaginal microenvironment.

Method used

Using a method based on fermentation of Lactobacillus, two Chinese medicines, snake bed and fermented, were fermented to form a new therapeutic drug. This drug achieves the effect of antibacterial, repairing mucosa and maintaining the vaginal ecological microenvironment through the anti-inflammatory and antibacterial effects of snake beds, mucosal repair and anti-inflammatory effects of phytosaccharides, and the microecological regulation of Lactobacillus.

Benefits of technology

This drug significantly inhibits the growth of Candida white, repairs vaginal mucosal damage, improves vaginal microenvironment, reduces inflammatory responses, and reduces drug resistance risks.

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Abstract

The present invention provides a fermented medicine prepared based on lactobacillus fermented Chinese medicine, and its preparation method and application. The present invention first uses a bacterial resuscitation method to realize the recovery and passage of lactobacillus, then prepares the medicine, and finally mixes the lactobacillus that grows well after passage with the medicine through a Chinese medicine fermentation method, and ferments to obtain a fermented medicine using lactobacillus fermented Chinese medicine. On the one hand, the fermented medicine of the present invention can play the anti-inflammatory and antibacterial effect of Cnidium monnieri, and on the other hand, Cuttlebone has the effect of repairing vaginal mucosa and maintaining vaginal microenvironment, and Cuttlebone has antibacterial and anti-inflammatory effects, which can assist Cnidium monnieri in antibacterial and anti-inflammatory effects, and the two have a synergistic effect. The medicine of the present invention has a strong effect of antibacterial and anti-inflammatory, repairing vaginal mucosa and maintaining vaginal ecological microenvironment. The preparation method of the present invention is simple and easy to promote, and can be applied to the preparation of anti-inflammatory and antibacterial infection, repairing vaginal mucosal damage, and promoting the growth of vaginal lactic acid bacteria.
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