Composition containing benzylamine acaricide and use thereof

Abstract

A composition comprising active ingredient a and active ingredient b, wherein active ingredient a is a compound of the general formula A, and active ingredient b is at least one compound having insecticidal, acaricidal or fungicidal activity which is different from the compound of the general formula A. The composition has the advantages of synergism, broadened spectrum of control, etc. and can be used for controlling various pests (especially mites) and plant diseases caused by various fungi, bacteria, nematodes, viruses.

Description

[0001] Cross-references to related applications

[0002] This application claims the benefit of Chinese Patent Application No. 202110169118.7, filed on February 7, 2021, the contents of which are incorporated herein by reference. Technical Field

[0003] This invention relates to the field of pesticides, and more specifically to a composition containing a benzylamine acaricide and its application. Background Technology

[0004] Throughout the history of pesticide development, the mixed use of pesticides has always been an integral part of pesticide development. Typically, a highly effective commercial pesticide is accompanied by many related mixtures, and the market value created by mixtures often exceeds that of single-agent pesticides.

[0005] Insecticides containing a single active ingredient, when used continuously for pest control, easily lead to the development of pesticide resistance. Mixing insecticides with two active ingredients in a specific ratio often improves efficacy, reduces the amount of active ingredient needed, saves costs, and delays the development of pesticide resistance. Therefore, pesticide compositions that simultaneously control one or more common plant pests and diseases, such as insects, mites, fungal diseases, nematode diseases, bacterial diseases, and viral diseases, can more effectively save agricultural costs, improve efficiency, and have excellent market application prospects. Thus, compositions possessing the above-mentioned effects have always been a sought-after goal. Summary of the Invention

[0006] The purpose of this invention is to overcome the technical problem of low pest control efficiency in the prior art and to provide a composition containing benzylamine acaricides, which has the advantages of synergistic effect and broadened control spectrum.

[0007] The compound represented by general formula A (active component a) can be used to control a variety of pests, especially agricultural mites, exhibiting outstanding control effects. In particular, this type of compound shows good control effects against various mites and pests such as the carmine spider mite, the two-spotted spider mite, the citrus psyllid, the apple psyllid, the broad mite, and nematodes. Through research on the mixing of the compound of general formula A with existing insecticides, acaricides, or fungicides, the inventors of this invention unexpectedly discovered that when active component a and active component b are used in combination, especially at a certain ratio, they exhibit even better effects in controlling insect pests, mites, or diseases, thus leading to this invention.

[0008] A first aspect of the present invention provides a composition comprising an active component a and an active component b, wherein the active component a is a compound represented by general formula A.

[0009]

[0010] Where n is 0 or 1;

[0011] R1 is methyl or chlorine;

[0012] R2 can be methyl, ethyl, propyl, butyl, isopropyl, cyclopropyl, cyclopropylmethyl, allyl, propargyl, fluoroethyl, difluoroethyl, trifluoroethyl, chloroethyl, trichloroethyl, or cyanoethyl.

[0013] R3 is either hydrogen or fluorine;

[0014] Active component b is at least one of the compounds with insecticidal, acaricidal, or bactericidal activities, different from the compound represented by general formula A; said active component b is selected from the following categories: acetylcholinesterase inhibitor insecticide b1, sodium ion channel regulator insecticide b2, nicotinic acetylcholine receptor agonist insecticide b3, chloride channel agonist insecticide b4, biomimetic juvenile hormone insecticide b5, mite growth inhibitor insecticide and acaricide b6, plant-derived and bio-derived insecticide b7, ATP synthase inhibitor insecticide and acaricide b8, oxidative phosphorylation uncoupling agent insecticide and acaricide b9, nicotinic acetylcholine receptor blocker insecticide (b10), insect growth inhibitor insecticide b11, mitochondrial electron transport complex III inhibitor insecticide and acaricide b12, mitochondrial electron transport complex I inhibitor insecticide and acaricide b13, voltage-dependent sodium ion channel blocker insecticide b14, acetylcholine... Coenzyme A carboxylase inhibitors (b15), mitochondrial electron transport complex II inhibitors (b16), ryanodine receptor modulators (b17), GABA-gated chloride channel allosteric modulators (b18), other insecticides (b19), amide fungicides (b20), dicarboxyimide fungicides (b21), triazole fungicides (b22), imidazole fungicides (b23), oxazole fungicides (b24), thiazole fungicides. Fungicides of the following types: b25, b26, b27, b28, b29, b30, b31, b32, b33, b34, b35, b36, b37, b38, b39, b39.

[0015] The second aspect of the present invention provides the use of the composition described in the first aspect for the prevention and control of pests or diseases, particularly for the prevention and control of mites. Detailed Implementation

[0016] The endpoints and any values ​​of the ranges disclosed herein are not limited to the precise ranges or values, and these ranges or values ​​should be understood to include values ​​close to these ranges or values. For numerical ranges, the endpoint values ​​of the various ranges, the endpoint values ​​of the various ranges and individual point values, and individual point values ​​can be combined with each other to obtain one or more new numerical ranges, which should be considered as specifically disclosed herein.

[0017] A first aspect of the present invention provides a composition comprising an active component a and an active component b, wherein the active component a is a compound represented by general formula A.

[0018]

[0019] Where n is 0 or 1;

[0020] R1 is methyl or chlorine;

[0021] R2 can be methyl, ethyl, propyl, butyl, isopropyl, cyclopropyl, cyclopropylmethyl, allyl, propargyl, fluoroethyl, difluoroethyl, trifluoroethyl, chloroethyl, trichloroethyl, or cyanoethyl.

[0022] R3 is either hydrogen or fluorine;

[0023] Active component b is at least one (two, three, four, five, six...) of compounds with insecticidal, acaricidal, or bactericidal activity, different from the compound represented by general formula A; said active component b is selected from insecticides b1 (acetylcholinesterase inhibitors), b2 (sodium ion channel regulators), b3 (nicotinic acetylcholine receptor agonists), b4 (chloride channel agonists), b5 (biomimetic juvenile hormones), b6 (mite growth inhibitors), b7 (plant-derived and bio-derived insecticides), b8 (ATP synthase inhibitors), b9 (oxidative phosphorylation uncoupling agents), b10 (nicotinic acetylcholine receptor blockers), b11 (insect growth inhibitors), b12 (mitochondrial electron transport complex III inhibitors), b13 (mitochondrial electron transport complex I inhibitors), and b14 (voltage-dependent sodium ion channel blockers). Insecticides b14, Acetyl-CoA carboxylase inhibitors, acaricides b15, Mitochondrial electron transport complex II inhibitors, acaricides b16, Ryeidine receptor modulators, insecticides b17, GABA-gated chloride channel allosteric modulators, insecticides b18, Other insecticides b19, Amide fungicides b20, Dicarboxylimide fungicides b21, Triazole fungicides b22, Imidazole fungicides b23, Oxazole fungicides b2 4. Thiazole fungicides (b25), Morpholine fungicides (b26), Pyrrole fungicides (b27), Pyridine fungicides (b28), Pyrimidine fungicides (b29), Quinazoline fungicides (b30), Carbamate fungicides (b31), Organophosphorus fungicides (b32), Thiocarbamate fungicides (b33), Plant growth regulators (b34), Copper preparations (b35), Mercury fungicides (b36), Nematicides (b37), Bactericides (b38), or other fungicides (b39).

[0024] According to some embodiments of the present invention, the weight ratio of active component a to active component b can be 150:1 to 1:150, such as 150:1, 125:1, 105:1, 99:1, 90:1, 85:1, 80:1, 70:1, 60:1, 50:1, 40:1, 30:1, 20:1, 10:1, 8:1, 6:1, 4:1, 2.5:1, 2:1, 1:1, 1:2, 1:2.5, 1:4, 1:6, 1:8, 1:10, 1:20, 1:30, 1:40, 1:50, 1:60, 1:70, 1:80, 1:90, 1:99, 1:105, 1:125, 1:150, or any value between the above values.

[0025] Acetylcholinesterase inhibitor insecticide B1 is selected from isoprocarb, carbofuran, thiamethoxam, carbofuran, methomyl, sec-butylcarbide, succinate, propoxur, phenoxycarb, oxadiazon, carbaryl, furazolidone, pirimicarb, oxadiazon, aldicarb, methyl ethyl ketone, methyl ethyl ketone sulfonate, nematicide, thiamethoxam, ethyl thiocarb, methyl thiocarb, chlorpyrifos, fenvalerate, fenpyroxenon, fenpyroxenon, phosmet, dimethoate, dioxin, pyrazophos, aldicarb, pyrimiphos, pyrazophos, thiamethoxam, fenpyroxenon, fenpyroxenon, fenpyroxenon, fenpyroxenon, fenpyroxenon, fenpyroxenon, dimethoate, dioxin, zicrolimus, pyridaben, fenpyroxenon ... iocarboxime), dicresyl, hyquincarb or carbanolate, chlorpyrifos, methyl chlorpyrifos, triazophos, phoxim, profenofos, profenofos, thiophanate-methyl, chlorpyrifos, fenitrothion, malathion, fenpyrophos, diazinon, fenthion, pyrazophos, pyrazophos, acephate, isofenphos, oxazolium, pyrazophos, butylpyrimidine phosphate, pyrimethanil, terbufos, terbufos, phosmet, dimethoate, omethoate, chlorpyrifos, phosmet, dibromophos, phosmet, trichlorfon, dichlorvos, acetamiprid, chlorpyrifos, thion, chlorpyrifos, methyl chlorpyrifos, acetamiprid, pyridaben, thion, chlorpyrifos, methyl chlorpyrifos, acetamiprid, pyridaben, phosmet ... Phosphorus, housefly phosphorus, fly venom phosphorus, ethion, methyl ethion, ethion, chlorpyrifos, phosmet, phosmet, phosmet, phosmet, phosmet, phosmet, methyl parathion, methamidophos, phosphonothion, phosmet, phosmet, dichlorvos, phosmet, monocrotophos, dibromophos, terbufos, floccopyr, phosmet, phosmet, phosmet, phosmet, ethion, phosmet oxychloride, phosmet ... Phosphorus, monothionylphosphonate, dithionylphosphonate, demeton-methyl demeton-methyl, sulfone phosphonate, propargite, isopyrphosphonate, chlorfenapyr, methyl ethyl phosphate, isosulfonate, sulfone phosphate, phosmet, cypermethrin, phosmet, phosmet, phosmet, methamidophos, methamidophos, methamidophos, phosmet, thiophanate-methyl, methyl pyrazophos, thiamethoxam, phosmet, dioxin, phosmet, aphid control Phosphorus, pyraclostrobin, pyrazophos, pyrazophos, pyridazin, chlorimide, oxazol, zolaprofos, pyraclostrobin, ethirimethonium, lirimfos, pyrimidine oxyphos, pyrimidine phosphorus, methyl pyrimidine phosphorus, thiazophos, bromoxynil, ethyl bromoxynil, trithion, chlorpyrifos, pyridaben, isochlorpyrifos, nephrine, phosmet, fenthion, phosphonophosphorus, phosphonophosphorus sulfoxide, fenthion, butylphosphine, tetramethylphosphine, terfenoxamylphosphine, phosphonophosphorus sulfoxide, benzoylphosphine, bromophenylphosphine, phosphonophosphorus sulfoxide, terfenoxamylphosphine ...Pyrazolium phosphate, quintiofos, bromfenvinfos, mazidox, pirimetaphos, prothidathion, azothoate, O-{2-[acetyl(ethyl)amino]-6-methyl-4-pyrimidinyl}O,O-diethyl thiophosphate, pyrimitate, quinalphos-methyl, athidathion, phosnichlor, trichlorfon (The list of phosphorus compounds is incomplete and cannot be translated.)

[0026] Sodium ion channel modulator insecticide B2 is selected from cypermethrin, lambda-cyhalothrin, cypermethrin, fenvalerate, flufenoxuron, cyhalofop-p-ethyl, lambda-cyhalothrin, bifenthrin, deltamethrin, flufenacet, cis-cypermethrin, bio-benzalofop-p-ethyl, trifluralin, permethrin, flufenacet, allethrin, bio-allethrin, cypermethrin, high-efficiency cypermethrin, high-efficiency trans-cypermethrin, zeta-cypermethrin, fenflurfen, and dextromethorphan. Ester, high-purity cypermethrin, acephate, chlorpyrifos, methoxybenzylflumethrin, tetrafluoromethrin, acephate, phenoxy ... Pentafluthrin, pyrethrin, S-cypermethrin, propargyl, propargyl, fenvalerate, thiamethoxam, methoxyfenozide, permethrin, bio-permethrin, propargyl, benzalkonium chloride, cyclopentylpyrethrin, bromocypermethrin, fenvalerate, trifluralin, benzylpyrethrin, fentanyl propionate, silafluofen, thiooxime, thiofluoxime, cypermethrin, barthrin, bioethanomethrin, fluvalinate, furthrin, heptafluthrin, momfluorothrin, transpermethrin, profluthrin, pyresmethrin, DDT, methoxydichlorophenoxy ...

[0027] Nicotinic acetylcholine receptor agonist insecticide B3 is selected from imidacloprid, thiamethoxam, acetamiprid, dinotefuran, thiamethoxam, acetamiprid, thiamethoxam, chlorpyrifos, flupyradifurone, piperazine, sulfadiazine, flupyradifurone, trifluralin, and flupyradifurone.

[0028] Chloride channel agonist insecticide B4 is selected from abamectin, methyl abamectin benzoate, rapamycin, and milbemycin.

[0029] The biomimetic juvenile hormone insecticide B5 is selected from acetamiprid, acetamiprid, pyriproxyfen, and phenoxycarb.

[0030] The mite growth inhibitor acaricide b6 is selected from tetradifon, flufenoxuron, thiamethoxam, and etoxazole.

[0031] Plant-derived and bio-derived insecticide B7 is selected from matrine, azadirachtin, Bacillus thuringiensis, Beauveria bassiana, allicin, neonicotinoid, carvacrol, d-limonene, nicotine, protonicotinoid, oxymatrine, pyrethrin, cinerins I, cinerin I, cinerin II, jasminoid I, jasminoid II, pyrethrin I, pyrethrin II, quassia, rhododendron-III, rotenone, ryania, selenorrhiza, resveratrol, Bacillus thuringiensis, Bacillus spheroides, sanguisorbin, or triptolide.

[0032] ATP synthase inhibitor insecticide and acaricide b8 is selected from diethyl ether, triazole tin, tricyclic tin, phenylbutazone, propargite, and trichlorfon.

[0033] Oxidized phosphoric acid uncoupling agent b9 is selected from chlorfenapyr, dinitrophenol, and fipronil.

[0034] Nicotinic acetylcholine receptor blocker insecticides B10 include sulfadiazine, fenitrothion, cypermethrin, and dichlorvos.

[0035] Insect growth inhibitors B11 are selected from diflubenzuron, lufenuron, flufenoxuron, diflubenzuron, chlorfenapyr, flufenoxuron, polyfluorourea, flufenoxuron, flufenoxuron, flufenoxuron, thiamethoxam, cyromazine, diflubenzuron, flufenoxuron, diflubenzuron, flufenoxuron, pyridabenone, epofenonane, tebufenozide, tebufenozide, pyriproxyfenozide, tebufenozide, furazolidone, chlorfenapyr, methoxyfenozide, tebufenozide, cyclofenozide, α-ecdysone, ecdysterone, bensulfuron, precocious hormone I, precocious hormone II, juvenile hormone I, juvenile hormone II, and juvenile hormone III.

[0036] The mitochondrial electron transport complex III inhibitor insecticide and acaricide b12 is selected from flufenoxuron, cypermethrin, pyrimethanil, and bifenazate.

[0037] Mitochondrial electron transport complex I inhibitor insecticide and acaricide b13 is selected from abamectin, abamectin, pyrimethanil, pyridaben, acetamiprid, rotenone.

[0038] Voltage-dependent sodium ion channel blocker insecticide B14 is selected from indoxacarb and cyfluthrin.

[0039] Acetyl-CoA carboxylase inhibitor b15 is an insecticide and acaricide selected from spirodiclofen, spirodiclofen, spirodiclofen diester, and methoxypiperidine ethyl ester.

[0040] The mitochondrial electron transport complex II inhibitor insecticide and acaricide b16 is selected from etoxazole, cyprodinil, diflubenzuron, and pyflubumide.

[0041] The ryanodine receptor modulator insecticide B17 is selected from chlorantraniliprole, flubendiamide, cyanantraniliprole, cyclobrombutanil, tetrachlorantraniliprole, and flubendiamide.

[0042] GABA-gated chloride channel allosteric modulator insecticide and acaricide b18 is selected from broflanilide, fluxametamide, and cyprofen.

[0043] Other insecticides, such as B19, are selected from pymetrozine, indoxacarb, cyfluthrin, chlorfenapyr, afidopyropen, allosamidin, chlorfenapyr, copper naphthenate, clomiphene, dichloroisocyanuric acid, fenoxacrim, fometoquin, flupyradifurone, flufenoxuron, mefenoxuron, tebufenozide, trichlorfon, pyridaben, trifluralin, pyrifluquinazon, ralfenoxuron, bromoxynil, benzoyl permethrin, pyridaben, fenpyroximate, fenpyroximate, fenpyroximate, fenpyroximate, fenpyroximate, fenpyroximate, fenpyroximate, copper sulfate, and ferric phosphate. Phosphate), metaldehyde, molluscicide, sodium pentachlorophenate, tralopyril, tributyltin oxide, spiromorph, dinoprop, pentamnitol, dinitrophenol, oxadiazon, chlorimide, phosmet, flufenerim, pyrimethanil, chlorfenapyr, sanguisorbin, spirotetramat, spiromesifen, thiamethoxam, thiamethoxam, diflubenzuron, triflumezopyrim, flucofuron, sulcofuron, maltodextrin, boric acid, diatomaceous earth, silica gel, triphenyltin, borax, lime sulfur, copper oleate, mercurous chloride, potassium thiocyanate or sodium thiocyanate. thiocyanate); chlordane, thiophanate-methyl, acetamiprid, fipronil, spinosad, ethyl spinosad, pymetrozine, pyrifluquinazon, bispyrimethanil, amitraz, flunitrazepam, acetamiprid, flupentiofenox, isoxazolamide, flupyrimin, nicofluprole, cyclobutrifluram, dimpropyridaz, oxazosulfyl, tyclopyrazoflor, spiropidion, benzpyrimoxan, dichloromezotiaz.

[0044] Dicarboxyimide fungicide B21 is selected from iprodione, isopropargyl, vinclozolin, fluchlorofluorocarbons, cymoxanil, thiophanate-methyl, acetamiprid, captan, captan, succinate, oxadiazon, isoprene, phosmet, or thiochlorfenphim.

[0045] Triazole fungicide B22 is selected from flutriafol, triadimefon, oxadiazon, tebuconazole, cyazofamid, propiconazole, thiophanate-methyl, tebuconazole, tetraflufenazole, oxytetracycline, fenbendazole, tebuconazole, cyproconazole, difenoconazole, tebuconazole, cyazofamid, flusilazole, triazole, hexaconazole, imidacloprid, tebuconazole, silflufenazole, triadimefon, bifenthrin, tricyclazole, fluquinazole, or oxadiazon.

[0046] The imidazole fungicide B23 is selected from carbendazim, imazalil, thiophanate-methyl, thiabendazole, carbendazim, cymoxanil, imazalil, thiophanate-methyl, benomyl, fluopyram, cyazofamid, imazalil, oxadixyl, isoprothiolane, albendazole, 2-(2-chlorophenyl)-1H-benzimidazole, cymoxanil, imazalil, mecarbinzid, or rabenzazole.

[0047] The oxazole fungicide B24 is selected from oxadiazon, pyridaben, oxamyl, oxamyl, hydrazine, metronidazole, or oxathiapiprolin.

[0048] Thiazole fungicide B25 is selected from thiamethoxam, tebuconazole, octothiazoline, benzothiazoline, flutianil, or thiadifluor.

[0049] Morpholine fungicide B26 is selected from aldimorph, benzamorf, dodecyl morpholine, butyl morpholine, morpholine, dimethomorph, flumorpholine, or tridemorpholine.

[0050] Pyrrole fungicide B27 is selected from seed dressing pyrrole or pyrrofenamic acid nitrile.

[0051] The pyridine fungicide b28 is selected from fluazinam, pyridaben, cyclopyridam, cyprodinil, bixafen, fluazinam, fluopyram, thiodiazole, pyraclostrobin, pyroxychlor, or pyroxyfur.

[0052] The pyrimidine fungicide b29 is selected from azoxystrobin, fluazinam, azoxystrobin, pyrimethanil, chlorpyrifos, fluazinam, ethirimol sulfonate, dimethylpyrimethanil, ethirimol, azoxystrobin, or triarimol.

[0053] Quinazolinone fungicide B30 is selected from acaricides such as miticide, anthraquinone, ethoxyquinoline, 8-hydroxyquinoline, propoxyquinoline, phenoxyquinoline, quinoline acrylate, quinacetol, or tebufloquin.

[0054] The carbamate fungicide b31 is selected from acetamiprid, isopropiconazole, benzimidazole, valiphenal (IR5885), cymoxanil, sulfadiazine, pyribencarb, meptyldinocap, iodocarb, picarbutrazox, or N-[(1S)-2-methyl-1-[[(4-methylbenzoyl)amino]methyl]propyl]carbamate-2,2,2-trifluoroethoxylate (tolprocarb).

[0055] Organophosphorus fungicide B32 is selected from dichlorvos, isoprothiolane, pyraclostrobin, methyl thiophanate, ampropylfos, isoprothiolane, ethionol, O-cyclohexyl O,S-diethylthiophosphate, benzyl isoprothiolane, seed phosphonophosphate, chlorpyrifos, or phosphonophosphorus.

[0056] Thiocarbamate fungicide B33 is selected from mancozeb, mancozeb, zinc thiocyanate, propineb, mancozeb, thiram, thiram, azithiram oxide, ferrous thiram, sodium thiocyanate, tecoram, mancozeb, mancozeb, mancozeb, or mancozeb.

[0057] Plant growth regulator B34 is selected from acibenzolar, 2-(acetoxy)benzoic acid, chitosan, clofibrate, triiodobenzoic acid, chlorophenoxyacetic acid, 2,4-D, 2,4-D butyric acid, phosmet, 2,4-D propionic acid, 2,4,5-tetrapropionic acid, indoleacetic acid, indolebutyric acid, naphthylacetamide, naphthaleneacetic acid, 1-naphthol, 1-naphthoxyacetic acid, potassium naphthenate, and sodium naphthenate. Naphthenate), 2,4,5-Tetramine, Cytokinin, Calcium Cyanamide, Thiamethoxam, Indomethacin, Ethephon, Merphos, Methoxyfenozide, Thiidin, Aviglycine, 1-Methylcyclopropene, ACC, Vinylsilane, Ethylenedioxime, Fenridazon, Spinosad, Gibberellins, Gibberic acid, Inducer, Cyproterinol, Butylmethionine, Phosphorus Chloride orphonium), chloranilide, furfural, glyphosate, flubendiamide, phosphonium oxychloride, glyphosate, isopyrimol, jasmonic acid, mepiquat, piperazine, prohydrojasmon, aniline, chlorfluren, chlorflurenol, dichlorflurenol, fluorene butyl ester, chlormequat chloride, butyrylhydrazine, furazolidone, flusulfanilamide, paclobutrazol, tetracycline Cycloazole, uniconazole, brassinolide, ethyl brassinolide, chlorpyrifos, chlorpyrifos, psoralen, pyridinol, triacontanol, cypermethrin, benzofluor, buminafos, carvone, choline chloride, ciobutide, clofencet, salicylic acid, cyanamide, cyclanilide, actinomycete, cyprosulfonamide de), propionyl brassinolide, indole, ethylene, furfural, paclobutrazol, oxime, holosulf, anti-dampness, karetazan, sulfonamide, cyclophosphamide, pydanon, cyhalothrin, pyrazol, anti-dampness ester, synergist, synergist phosphorus, methyl synergist phosphorus, octafluorodipropyl ether, synergist ether, synergist ring, synergist aldehyde, synergist ester, synergist powder, sesamin or synergist sulfone.

[0058] Copper preparation B35 is selected from acypetacs-copper, Bordeaux mixture, sodium carbonate Bordeaux mixture, Cheshinte mixture, copper acetate, copper carbonate, copper oxychloride, copper silicate, basic copper sulfate, copper zinc chromate, cufraneb, cuprobam, cuprous oxide, mancozeb, or quinoline copper.

[0059] Mercury-based bactericide B36 is selected from mercuric chloride, mercuric oxide, mercuric bromide, ethyl acetate chloride, ethylmercury bromide, ethyl mercuric chloride, ethyl 2,3-dihydroxypropyl alkoxide, ethyl mercuric phosphate, sulfamethoxymercury, 2,3,7-triphenyltetrazole chloride, methylmercury benzoate, methylmercury dicyandiamide, pentachlorophenol mercury, 8-phenylmercurioxyquinoline, phenylmercuriurea, phenylmercuric acetate, phenylmercuric chloride, phenylmercury derivative of pyrocatechol, phenylmercuric nitrate, phenethyl salicylate, or tolylmercury acetate.

[0060] Nematicide B37 is selected from benclothiaz, methyl bromide, iodomethyl, methyl thiophanate, dimethoate, dazomet, dichloroisopropyl ether, thiamethoxam, thionyl phosphate, fensodium, chlorpyrifos, fenpropathrin, chlorpyrifos, chlorpyrifos, thiamethoxam, aldicarb, carbofuran, thiodimethyl fluoride, dichloropropene, fluensulfone, furfural, tioxazafen, or xylenols.

[0061] Bactericide B38 is selected from the following: kasugamycin, myxothiazol, polyoxin, polyoxin, pseudomycin, PSF-D, effectivemycin, jinggangmycin, streptomycin, seed dressing agent, tebuconazole, bromonitrile glycol, tebuconazole, chloramphenicol, copper hydroxide, guaiacol, dichlorophenol, dipyrithione, doxycycline, allicin, sodium dichloroisocyanurate, formaldehyde, hexachlorophenol, mercurochrome, 8-hydroxyquinoline, trichloromethylpyridine, octahedrone, quinacrine, oxytetracycline, tebuconazole, allylbenzylthiazide, thiamethoxam, tebuconazole copper, tebuconazole, thiamethoxam copper, thimerosal, octahedrone, or thiamethoxam zinc.

[0062] Other fungicides, such as B39, are selected from a variety of fungicides including isoprothiolane, pentachloronitrobenzene, aluminum fosetyl-aluminum, sulfur, copper oxychloride, cuprous oxide, activated ester, benomyl, bethoxazin, pyridaben, benzyl benzoate, tetrachlorophthalide, spirocycline, pyrazosulfanilamide, GY-81, NKI-42650, chlorpyrifos, indolesulfonamide, zopfiellin, cyazofamid, acypetacs, allyl alcohol, bromochlorophenazine, dehydroacetic acid, and diethyl pyrocarbonate. pyrocarbonate), seed coating ester, hexachlorobutadiene, nitrostyrene, phthalimide, OCH, pentachlorophenyl dodecanoate, o-phenylphenol, piperazine, proparamid, quinolones, sodium orthophenylphenoxide, sulfone, thiamethoxam, acypetacs-zinc, polyoxorim-zinc, zinc naphthenate, trichlorophenoxide, ametoctradin, triflufenazole, cyproconazole, chlorothalonil, dichloronaphthoquinone, thiophanate-methyl, tetrachloroquine, tetrachlorop-quinoline, dichloronaphthoquinone, fenpyrazamine, barium polysulfide, potassium polysulfide, sodium polysulfide, decafentin, potassium azide. (azide), sodium azide, benzamacril, thiochlorophenol, diphenylamine, chlorophenpyridine, berberine, osthol, artemisinin, bentaluron, chlobenthiazone, thiophanate-methyl, pyriofenone, thiram, thiram, biphenyl, chlorodinitronaphthalenes, chlorobenzene, phenazine, hexachlorobenzene, tetrachloronitrobenzene, trichlorotrinitrobenzenes, 2-aminobutane, cypermethrin, flufenoxuron, ribavirin, toluenesulfonamide, doxycycline, biguanide octyl salt, biguanide octylamine, cymoxanil or pendimethalin.

[0063] In some embodiments of the present invention, the active component a is selected from compounds with the following structures:

[0064]

[0065] And / or, the active component b is selected from profenofos, triazophos, malathion, phoxim, chlorpyrifos, acetamiprid, fipronil, bromfenoxam, bifenthrin, cypermethrin, lambda-cyhalothrin, lambda-cyhalothrin, imidacloprid, acetamiprid, thiamethoxam, thiamethoxam, dinotefuran, acetamiprid, flupyrflufenoxam, flupyridine, abamectin, methyl abamectin, pyriproxyfen, pymetrozine, difenoconazole, buprofen, triazophos, spirotetramat, acetamiprid, rotenone, indoxacarb, chlorantraniliprole, flubendiamide, cyantraniliprole, cyclobromiprid, tetrachlorantraniliprole, flupyrraniliprole, tetrazole, flupyridine, broflanilide, fluxametamide, isocycloseram, and cycloprofen.

[0066] According to some embodiments of the present invention, the active component a is selected from compounds with the following structures:

[0067]

[0068]

[0069] According to some embodiments of the present invention, the active component b is selected from tetradifon, flufenoxam, thiamethoxam, etoxazole, propargite, spirodiclofen, spirodiclofen, methoxyfenozide, pyridaben, bifenazate, pyridaben, cyprodinil, etoxazole, diflubenzuron, acyclovir, acetonitrile, and flupentiofenox.

[0070] According to some embodiments of the present invention, the active component a is selected from compounds with the following structures:

[0071]

[0072] According to some embodiments of the present invention, the active component b is selected from propiconazole, flutriafol, tebuconazole, prothioconazole, difenoconazole, hexaconazole, tebuconazole, fenpyroxen, triadimefon, flusilazole, carbendazim, prochloraz, cyazofamid, pyraclostrobin, dimethomorph, flumorph, fludioxonil, fluazinam, cyproconazole, ethirimol, ethoxysulfuron, mancozeb, thiram, metalaxyl, mancozeb, Bordeaux mixture, thiamethoxam, thiazoxone, chlorfluazuron, fluopyram, fluopyram, thifluzamide, fluopyram, fluopyram, fluopyram, fluopyram, azoxystrobin, pyraclostrobin, pyraclostrobin, pyridaben, and oxadiazon.

[0073] The composition provided by this invention has advantages such as synergistic effect and broadening of the prevention and treatment spectrum. The composition provided by this invention is suitable for controlling a variety of important agricultural and forestry pests, storage pests, and urban sanitation pests, including *Citrus parvum*, *Citrus citrus leafhopper*, *Citrus citrus var. citrus*, *Citrus citrus gall mite*, *Citrus haematomarginatus*, *Citrus cinnabarinus*, *Citrus two-spotted*, *Citrus apple*, *Citrus truncatula*, *Citrus pulcherrima*, *Citrus pulcherrima*, *Citrus pulcherrima*, *Citrus oviductus*, *Citrus jujube*, *Citrus datura*, *Citrus thunbergii*, *Citrus thunbergii*, *Citrus pulcherrima ... Corn yellow thrips, rice weevil, rice water weevil, rice stem borer, large stem borer, sorghum stripe borer, Taiwan leaf borer, rice mud beetle, rice root leaf beetle, rice root weevil, millet scale leaf beetle, bean turnip, hemp flea beetle, rice leaf roller, straight-striped rice skipper, brown planthopper, white-backed planthopper, gray planthopper, rice leafhopper, Chinese rice grasshopper, rice gall midge, rice black bug, rice stem borer, black-tailed leafhopper, white-winged leafhopper, large Green leafhopper, grape two-spotted leafhopper, peach one-spotted leafhopper, two-spotted black-tailed leafhopper, cotton leafhopper, electric leafhopper, spotted leafhopper, black grasshopper, rice midge, rice stem fly, rice leaf miner, rice water maggot, wheat long-tubed aphid, wheat two-forked aphid, cereal constrictor aphid, corn aphid, wheat mite, armyworm, wheat red midge, sunflower leaf borer, millet borer, wheat stem fly, wheat leaf beetle, East Asian migratory locust, Asian migratory locust, western Tibetan migratory locust, small rice locust, clumsy locust, large-cushioned pointed-winged locust, long-winged plain wood locust, short-star-winged locust, broad-winged curved-backed locust, Asian small car locust, yellow-legged small car locust, Chinese sword-horned locust, short-fronted carrying locust, shank green-striped locust, broad-bearded ant locust, white-edged scab locust, corn borer, grain flea beetle, striped stem borer, sorghum aphid, chestnut gall wasp, sweet potato hawk moth, sweet potato wheat moth, grassland moth, millet gray moth, sweet potato weevil, potato tuber moth, Soybean pod borer, soybean leafminer, soybean pod borer, soybean stem leafminer, soybean hawk moth, soybean root leafminer, gray barnacle snail, homotypic barnacle snail, slug, cotton aphid, carmine spider mite, green blind stink bug, medium black blind stink bug, alfalfa mirid bug, three-spotted blind stink bug, spotted stink bug, tea-winged stink bug, pear lace bug, cotton red bollworm, cotton leafroller, walnut leaf-bearing moth, cotton bollworm, cotton bridge-building insect, cotton leafroller, cotton leafhopper, cotton thistle Horse, Green-striped Diamond Aphid, Dingdian Diamond Aphid, Egyptian Diamond Aphid, Peach Aphid, Radish Aphid, Cabbage Aphid, Soybean Aphid, Peanut Aphid, Peanut Aphid, Lettuce Fingernail Aphid, Cabbage White Butterfly, Spotted Bean White Butterfly, Citrus Swallowtail, Jade-banded Swallowtail, Diamondback Moth, Beetroot Moth, Spodoptera litura, Cabbage Moth, Silver-striped Moth, Soybean Small Moth, Cabbage Moth, Yellow-striped Flea Beetle, Potato Ladybug, Eggplant Twenty-eight-spotted Ladybug, Indian Cucumber Beetle, Wheat Leaf Beetle, American Serpentine Leafminer, Tomato Serpentine Leafminer, South American Serpentine Leafminer, Clover Serpentine Leafminer, Tobacco Hawk Moth, Spiral Leafminer, Golden-striped Fine Moth, Peach Leafminer, Pear Leafminer, Pear Tiger, Yellow Cucumber Beetle, Tobacco Whitefly, Greenhouse Whitefly, Lateral Multiphasic Tarsus Mite, Ape Leaf Beetle, Palm Thrips, Melon Moth, Green Planthopper, Large Bag Moth, Yellow-tailed Tussanthus Moth, Brown-edged Green Tussanthus Moth, Stealing MothAmerican white moth, red-bellied white-light moth, apple boat moth, cotton geometrid moth, woodlouse geometrid moth, jujube geometrid moth, persimmon geometrid moth, cotton bead scale, grass scale, oriental helmet scale, wrinkled large ball scale, Japanese wax scale, Comstock mealybug, persimmon mealybug, soybean root mealybug, persimmon mealybug, pile wax mealybug, grape mealybug, pear white shield scale, mulberry white scale, elm shield scale, arrowhead scale, chrysanthemum scale, rose white-wheel shield scale, mulberry shield scale, arrowhead shield scale, cottony cushion scale, Korean ball scale, star longhorn beetle, peach longhorn moth, mulberry longhorn beetle, spherical star longhorn beetle, peach red-necked longhorn beetle, cloud-spotted longhorn beetle, pear-eyed longhorn beetle, grape spine longhorn beetle, hemp longhorn beetle, apple branch longhorn beetle, chrysanthemum small Longhorn beetle, walnut gall moth, grape tiger moth, grape hawk moth, grape clearwing moth, grape root phylloxera aphid, spirea aphid, apple woolly aphid, rose long-tubed aphid, pear two-forked aphid, pear yellow powdery aphid, chestnut aphid, edged chestnut aphid, citrus aphid, pear fruit moth, peach fruit moth, pear stem sawfly, pear gall moth, aromatic wood-boring moth, coffee wood-boring moth, apple clearwing moth, golden-edged jewel beetle, apple small jewel beetle, plum small fruit moth, white small fruit moth, apple leafroller, yellow-spotted longwing leafroller, citrus yellow leafroller, black-spotted wheat moth, apple nest moth, pear star-shaped caterpillar, jujube gall midge, top shoot leafroller, peach fruit borer, peach fruit borer, Chinese pear Psyllids, black spiny whiteflies, spiny root mites, wheat leaf claw mites, citrus leafminers, citrus fruit flies, citrus psyllids, lychee fruit borers, lychee stink bugs, lychee gall mites, lychee longhorn beetles, mango weevils, banana weevils, persimmon moths, walnut leafminers, walnut weevils, chestnut weevils, sugarcane two-spotted stem borers, sugarcane yellow stem borers, sugarcane white stem borers, sugarcane beetles, sugarcane aphids, sugarcane thrips, sugarcane mealybugs, corn weevils, grain borers, grain beetles, saw-toothed grain beetles, rice weevils, coffee bean weevils, four-striped bean weevils, tobacco leafminers, Mediterranean mealybugs, black rice weevils, one-spotted grain borers, purple-spotted grain borers, long-horned flat grain beetles, red-spotted grain beetles, large grain beetles The following species are listed: Rice weevil, sawtooth rice weevil, flat rice weevil, dwarf rice weevil, Turkish flat rice weevil, rusty red flat rice weevil, black fungus weevil, black mealworm, yellow mealworm, green bean weevil, pea weevil, broad bean weevil, Indian meal borer, wheat moth, Indian meal borer, powdery moth, booklice, carrion mite, back-breasted exposed tail beetle, yellow-spotted exposed tail beetle, tobacco beetle, medicinal herb beetle, spotted carpet beetle, black-spotted carpet beetle, Japanese spider beetle, pseudo-naked spider beetle, housefly, goldfly, green fly, blowfly, flesh fly, burrowing fly, German cockroach, American cockroach, Japanese cockroach and Australian cockroach, black-breasted cockroach, brown-spotted cockroach, sugarcane cockroach, red ant, small yellow house ant, flower house ant, Anopheles mosquito, Culex mosquito, Aedes mosquito.

[0074] The composition provided by this invention can also control plant diseases caused by various fungi, bacteria, and nematodes, including wheat stripe rust, wheat leaf rust, wheat stem rust, wheat scab, wheat yellow dwarf virus, wheat dwarf virus, wheat soil-borne mosaic virus, wheat stripe mosaic virus, wheat linear mosaic virus, wheat loose smut, wheat stem smut, wheat flat smut, wheat powdery mildew, wheat take-all, wheat sheath blight, wheat downy mildew, wheat nematode disease, barley stripe disease, barley net blight, wheat snow mold leaf blight, wheat helical root rot leaf spot, rice blast, rice false smut, rice sheath blight, rice bacterial leaf blight, rice bacterial stripe, rice sesame leaf spot, rice bakanae disease, rice dry tip nematode disease, rice seedling rot, rice sclerotium rot, rice stripe leaf blight, rice common dwarf virus, and rice Corn wilt, corn large and small leaf spot, corn round leaf spot, corn smut, corn smut, corn bacterial wilt, corn dwarf mosaic virus, corn rough dwarf virus, corn bacterial wilt, corn downy mildew, corn curvularia leaf spot, corn gray leaf spot, corn anthracnose, corn take-all, sorghum smut, sorghum loose smut, sorghum firm smut, sorghum long-grain smut, sorghum anthracnose, sorghum blue mold glume blight, sorghum black tuft, sorghum top rot, sorghum flower smut, millet white spot disease, millet smut, millet red leaf disease, sweet potato black spot, garlic sprout root rot, garlic sprout root-knot nematode disease, sweet potato virus disease, sweet potato storage diseases, potato virus disease, potato ring rot, potato late blight, potato early blight, potato canker, soybean herbicide leaf disease, soybean top rot Soybean wilt, soybean sclerotinia rot, soybean root rot, soybean cyst nematode disease, soybean gray spot, soybean downy mildew, soybean bacterial blight, soybean bacterial spot, soybean purple blotch, soybean brown spot, soybean rust, peanut root-knot nematode disease, peanut stem rot, peanut black spot, peanut brown spot, peanut net blotch, peanut rust, peanut virus disease, cotton wilt, cotton verticillium wilt, cotton seedling diseases, cotton angular leaf spot, cotton boll diseases, flax rust, flax wilt, tobacco black shank, tobacco anthracnose, tobacco red spot, tobacco virus disease, tobacco root-knot nematode disease, beet brown spot, beet powdery mildew, beet root rot, beet root rot, pear scab, pear rust, pear ring rot, pear black spot, pear brown rot, pear blight, apple tree rot, apple rust Apple leaf diseases, apple rust, apple mosaic virus, apple orchard root rot, apple root rot, apple purple root rot, apple white root rot, apple anthracnose, apple ring rot, apple blue mold, apple heart rot, apple tiger skin disease, apple bitter pit, apple scab, apple blight, apple core rot, apple moldy heart disease, grape white rot, grape black rot, grape downy mildew, grape anthracnose, grape brown spot, grape rachis brown blight, grape gray mold, jujube witches' broom, jujube rust, jujube fruit shrinkage, fruit tree crown cancer, seedling diseases of solanaceous vegetables, tomato virus diseases, tomato leaf mold, tomato canker, tomato wilt, tomato verticillium wilt, tomato early blight, tomato leaf spot, tomato leaf mold, tomato gray mold, tomato powdery mildew, tomato brown spot, tomato downy mildew.Anthracnose of peppers, blight of peppers, scab of peppers, downy mildew of cucumbers, anthracnose of cucurbits, wilt of cucurbits, powdery mildew of cucurbits, viral diseases of cucurbits, gray mold of cucurbits, black spot of cucumbers, blight of cucumbers, sclerotinia rot of cucumbers, bacterial angular leaf spot of cucumbers, viral diseases of cruciferous vegetables, soft rot of cruciferous vegetables, downy mildew of cruciferous vegetables, black spot of cruciferous vegetables, clubroot of cruciferous vegetables, sclerotinia rot of cruciferous vegetables, black rot of cruciferous vegetables, leaf spot of peanuts, powdery mildew of strawberries, leaf spot of bananas, wilt of bananas, bunchy top of bananas, heart rot of bananas, anthracnose of bananas, black spot of bananas, sclerotinia rot of rapeseed. Downy mildew of rapeseed, rapeseed wilt and infertility, sesame wilt, sesame stem blight, sunflower sclerotinia rot, sunflower black spot, brown rot of peach, apricot and plum, peach root cancer, peach anthracnose, peach shot-hole disease, peach leaf curl, peach tree rot, peach and apricot black spot, peach tree gummosis, persimmon angular leaf spot, persimmon round spot, persimmon anthracnose, gray mold of strawberry, chestnut wilt, walnut black spot, walnut anthracnose, hawthorn flower rot, kiwifruit canker, bacterial blight of beans, rust of beans, anthracnose of beans, wilt of beans, leaf spot of celery, early blight of celery, purple spot of onion, root-knot nematode disease of vegetables, ginger wilt.

[0075] The inventors of this invention have discovered through research that indoor bioactivity tests show that the insecticidal, acaricidal, or bactericidal compositions of this invention have a synergistic effect.

[0076] Therefore, a second aspect of the present invention provides the use of the composition described in the first aspect for the control of pests (especially mites) or diseases. The pests and diseases are as described above.

[0077] According to some embodiments of the present invention, the composition is used to control pests, mites or diseases by applying it directly or indirectly to the pests, mites or fungi or their growth medium at an effective dose of 10 to 5000 grams per hectare.

[0078] In this invention, there is no particular limitation on whether the method is direct or indirect, as long as it can achieve the purpose of preventing and controlling pests, mites, or diseases. For example, the direct method may include directly contacting the composition of this invention with insects, mites, or fungi; the indirect method may include treating the place where insects, mites, or fungi grow or appear with the composition of this invention or treating their food chain containing the composition of this invention.

[0079] The compositions of the present invention can be provided in the form of finished formulations. For example, they can be formulated as emulsifiable concentrates, suspensions, water-dispersible granules, water emulsions, microemulsions, soluble liquids, wettable powders, oil suspensions, etc., as needed.

[0080] In the compositions of the present invention, the cumulative weight percentage content of active components a and b is between 0.5% and 95%, preferably between 1% and 85%.

[0081] The content of the active ingredient in the composition of the present invention depends on the dosage when used alone, as well as on the mixing ratio and the degree of synergistic effect. The optimal range of the active ingredient content may vary depending on the formulation type of the composition.

[0082] The formulations of the present invention can be prepared by conventional processing methods, such as mixing the active substance with a liquid carrier (solvent) or a solid carrier, and then adding one or more adjuvants (e.g., emulsifiers, dispersants, wetting agents, binders, stabilizers, and defoamers). Preferably, in the present invention, the composition contains at least one carrier and at least one surfactant. Preferably, in all the foregoing cases, it should be ensured that the active components in the compositions of the present invention are uniformly distributed.

[0083] In this invention, the emulsifiable concentrate typically contains 10-75% active ingredient, 2-20% emulsifier, 0-20% other additives (e.g., stabilizers, penetrants, corrosion inhibitors, etc.) and solvent by weight percentage, and may also contain co-solvent if necessary.

[0084] In this invention, the suspending agent is typically milled to obtain a stable, non-depositing, flowable product. By weight percentage, the suspending agent typically contains 5-50% active ingredient, 5-15% dispersant, 0.1-10% wetting agent, 4-10% antifreeze, 0-10% other additives (e.g., defoamers, preservatives, stabilizers, penetrants, and thickeners), and the balance being a liquid carrier.

[0085] In this invention, the water-dispersible granules are typically formulated as 10-100 international standard sieve mesh (1.676-0.152 mm) particles, which can be prepared by extrusion, impregnation, or spray granulation methods. By weight percentage, the water-dispersible granules typically contain 0.5-80% active ingredient and 5-20% adjuvants (e.g., dispersants, wetting agents, disintegrants, and binders), with the balance being an inert carrier.

[0086] In this invention, the wettable powder typically contains 10-85% active ingredient by weight, 3-10% dispersant in addition to a solid inert carrier, and may also contain 0-10% wetting agent and / or other additives (e.g., penetrants or stabilizers).

[0087] In this invention, the water-in-oil emulsion is formed by mixing the active ingredient, organic solvent, and surfactant to form an oil phase; water and antifreeze are then mixed together to form a homogeneous and transparent aqueous phase. The oil phase is sheared at high speed using a high-shear emulsifier, while the aqueous phase is slowly added to the oil phase simultaneously. By weight percentage, the water-in-oil emulsion typically contains 1-60% active ingredient, 5-20% surfactant, 2-10% antifreeze, and the balance being water.

[0088] In this invention, the microemulsion is a homogeneous, transparent liquid formed by mixing the active ingredient, organic solvent, emulsifier, and water together. By weight percentage, the microemulsion typically contains 1-50% active ingredient, 10-40% emulsifier, 40-60% organic solvent, and the balance being water.

[0089] In this invention, the soluble liquid is a homogeneous, transparent liquid formed by mixing the active ingredient, organic solvent, and surfactant together. By weight percentage, the soluble liquid typically contains 1-50% active ingredient, 6-20% surfactant, and the balance being organic solvent.

[0090] In this invention, the oil suspension is produced by adding the active component, surfactant, and oil-based carrier to a sand mill and milling until the particle size meets the requirements. By weight percentage, the oil suspension typically contains 2-60% active component, 6-20% surfactant, and the remainder oil-based carrier.

[0091] In this invention, aqueous dispersions and emulsions (e.g., compositions obtained by diluting the emulsifiable concentrate, wettable powder, or concentrate of this invention with water) are also within the scope of this invention. The emulsions described above (including the aforementioned forms) may be water-in-oil or oil-in-water, and may have a thick, paste-like consistency.

[0092] The formulations of the present invention can be prepared using (liquid or solid) carriers and various adjuvants known to those skilled in the art. These include, but are not limited to, the following substances:

[0093] Suitable liquid carriers or solvents can be water, various aromatic hydrocarbons, aliphatic hydrocarbons, ketones, ethers, etc., such as toluene, xylene, acetone, cyclohexanone, xylene, benzene, cyclohexane, isopropanol, ethylene glycol, sorbitol, methanol, ethanol, butanol, dimethylformamide, naphthalene, machine oil, petroleum ether, cyclohexanone, methyl oleate, methyl soybean oil, etc., one or more of these.

[0094] Suitable solid carriers include natural or synthetic clays and silicates. Solid carriers suitable for powders include naturally formed rock powders, chalk, quartz, clay, montmorillonite, silica, diatomaceous earth, pumice, gypsum, talc, bentonite, kaolin, clay, and synthetic ground minerals (such as micro-dispersed silica or alumina). Suitable particulate carriers include crushed and graded natural rocks such as calcite, marble, pumice, sepiolite, and dolomite, as well as synthetic particles made from organic and inorganic powders.

[0095] Suitable co-solvents can be one or more of methanol, phenol, isoamyl alcohol, dimethyl sulfoxide, ethyl acetate, butanone, dimethylformamide, tetradecyl alcohol, etc.

[0096] Suitable emulsifiers can be one or more of the following: ethoxylated castor oil, polyoxyethylene (n20) phenylethyl phenol ether oleate, alkyl aryl polyoxyethylene polyoxypropylene ether, alkyl aryl formaldehyde resin polyoxyethylene ether, diphenylphenol polyoxyethylene (n18) ether formaldehyde condensate, sodium dodecyl sulfate, agricultural emulsion 0201B, agricultural emulsion 0203B, agricultural emulsion T-20, agricultural emulsion S-80, agricultural emulsion 507#, agricultural emulsion 100#, agricultural emulsion 36#, agricultural emulsion 600#, agricultural emulsion 1601#, agricultural emulsion 2201#, agricultural emulsion 700#, agricultural emulsion NP-7, and agricultural emulsion NP-15.

[0097] Suitable dispersants can be one or more of the following: sodium lignosulfonate, calcium lignosulfonate, methylnaphthalenesulfonate formaldehyde condensate, sodium methylnaphthalenesulfonate formaldehyde condensate, sodium methylenenaphthalenesulfonate, sodium oleate methylaminoethyl sulfonate, epoxy polyether, p-tert-butyl ether, piperyl butyl ether, alkylamide taurate, dibutylnaphthalenesulfonate formaldehyde condensate, alkylphenol polyoxyethylene phosphate, methylcellulose, sodium salt of naphthol sulfonate formaldehyde condensate, etc.

[0098] Suitable wetting agents can be one or more of sodium sulfate, sodium lauryl sulfate, sodium methylene naphthalene sulfonate, sodium dodecylbenzene sulfonate, calcium dodecylbenzene sulfonate, sodium alkyl naphthalene sulfonate, fatty alcohol polyoxyethylene ether, alkylphenol polyoxyethylene ether, etc.

[0099] Suitable thickeners can be synthetic (such as carbonyl methyl alcohol, polyvinyl alcohol, polyvinyl acetate) or natural water-soluble polymers (such as xanthan gum, gelatin, gum arabic, polyvinylpyrrolidone, magnesium aluminum silicate, polyvinyl alcohol, polyethylene glycol, phenolic resin, shellac, carboxymethyl cellulose, and sodium alginate, etc.), added to the formulation in powder, granule or latex form.

[0100] Suitable defoamers can include defoaming agents, silicones, C8-10 fatty alcohols, phosphate esters, C10-20 saturated fatty acids (such as decanoic acid), and amides.

[0101] Suitable oxidants can be potassium chlorate, sodium chlorate, potassium perchlorate, sodium nitrate, potassium nitrate, potassium permanganate, etc.

[0102] Suitable adhesives can include polyvinyl alcohol, polyvinyl acetate, xanthan gum, gelatin, carboxymethyl cellulose, soluble starch, polyethylene glycol 8000, and sodium alginate, etc.

[0103] In this invention, preferably, when used to control urban pests, it can be formulated as an aerosol containing a propellant, or as a bait composition containing, in addition to the active ingredient, one or more food materials suitable for insect feeding, optional attractant, and optional wetting agent.

[0104] In this invention, the combination of active component a and the compounds listed in (b1)-(b19) of active component b in the composition is suitable for the prevention and control of a variety of important agricultural and forestry pests and mites; the combination of active component a and the compounds listed in (b20)-(b39) of active component b in the composition is suitable for the prevention and control of a variety of harmful bacteria, especially a variety of fungal diseases, bacterial diseases, nematode diseases, viral diseases, and a variety of storage diseases of cereals, vegetables, fruit trees, ornamental plants, lawns and tropical crops.

[0105] According to a preferred embodiment of the present invention, the present invention provides the application of a composition in the control of mites, the composition comprising active component a and active component b, wherein active component a comprises a compound having the structure shown in formula I-53 and / or formula I-1202; and active component b is selected from tetradifon and / or thiamethoxam.

[0106]

[0107] The weight ratio of active component a to active component b is 1:(5-30).

[0108] According to a preferred embodiment of the present invention, the above composition includes active component a and active component b, wherein active component a is a compound having the structure shown in Formula I-1202; and active component b is selected from tetradifon.

[0109]

[0110] The weight ratio of active component a to active component b is 1:(20-30).

[0111] The following specific embodiments are provided to further illustrate the present invention, but the invention is by no means limited to these examples. All percentages or proportions of components in the embodiments are by weight. The active ingredients in each formulation are calculated based on their effective content.

[0112] In the following examples, compounds A1, A2, A3, A4, A5, A6, A7, A8, A9, A10, A11, and A12 correspond to compounds I-53, I-54, I-55, I-57, I-69, I-71, I-303, I-305, I-1202, I-1204, I-1206, and I-1218 in List I of CN111825585A, respectively.

[0113] Formulation Examples

[0114] Formulation Example 1

[0115] Preparation of 25% etoxazole compound A5 emulsifiable concentrate

[0116] According to the formula requirements, add 5 parts etoxazole, 20 parts compound A5, 7 parts agricultural emulsion 0201B, 3 parts agricultural emulsion NP-15, 2 parts agricultural emulsion 700#, 12 parts dimethylformamide, and 51 parts xylene by weight, respectively, mix well, and if necessary, heat in a hot water bath to dissolve, thus obtaining 25% etoxazole·compound A5 emulsifiable concentrate.

[0117] Formulation Example 2

[0118] Preparation of 35% diflubenzuron compound A2 oil suspension

[0119] According to the formula requirements, by weight, 20 parts of dicofol, 15 parts of compound A2, 6 parts of agricultural emulsion 0201B, 2 parts of agricultural emulsion 700#, 5 parts of agricultural emulsion S-80, 10 parts of methyl oleate, 3 parts of silica, 1 part of agricultural emulsion T-20, and 33 parts of methylated soybean oil are added to a sand mill and ground into a fine powder to prepare a 35% dicofol·compound A2 oil suspension.

[0120] Formulation Example 3

[0121] Preparation of 30% propargite compound A3 water emulsion

[0122] According to the formulation requirements, by weight, 20 parts of propargite, 10 parts of compound A3, 8 parts of alkyl aryl polyoxyethylene polyoxypropylene ether, 5 parts of agricultural emulsion 2201#, 15 parts of dimethylformamide, and 0.5 parts of tetradecanol are added together to dissolve into a homogeneous oil phase. Under high-speed stirring, 41.5 parts of water are added to form a well-dispersible 30% propargite·compound A3 water emulsion.

[0123] Formulation Example 4

[0124] Preparation of 35% Butyl ether urea compound A4 water emulsion

[0125] According to the formulation requirements, by weight, 15 parts of butyl ether urea, 20 parts of compound A4, 8 parts of polyoxyethylene (n20) phenylethyl phenol oleate, 3 parts of calcium dodecylbenzene sulfonate, 2 parts of agricultural emulsion 507#, 5 parts of dimethylformamide, and 3 parts of tetradecyl alcohol are added together to dissolve into a homogeneous oil phase. Under high-speed stirring, 44 parts of water are added to form a well-dispersible 35% butyl ether urea·compound A4 water emulsion.

[0126] Formulation Example 5

[0127] Preparation of 30% Pyridaben Compound A6 Wettable Powder

[0128] According to the formula requirements, by weight, 20 parts of pyridaben, 10 parts of compound A6, 2 parts of sodium dodecyl sulfate, 6 parts of sodium naphthol sulfonate formaldehyde condensate, 4 parts of sodium lignosulfonate, 5 parts of silica, and 53 parts of bentonite are thoroughly mixed and then pulverized by an ultrafine pulverizer to obtain 30% pyridaben·compound A6 wettable powder.

[0129] Formulation Example 6

[0130] Preparation of 30% Cyclopyralid·Compound A1 Water Dispersible Granules

[0131] According to the formula requirements, by weight, 25 parts of cypermethrin, 5 parts of compound A1, 15 parts of sodium methylnaphthalenesulfonate formaldehyde condensate, 5 parts of sodium alginate, 5 parts of polyethylene glycol 8000, 15 parts of sodium sulfate, and 30 parts of bentonite are mixed and pulverized. Water is then added and kneaded, and the mixture is granulated in a granulator equipped with a sieve of a specific size. After drying and sieving (according to the sieve size range), 30% cypermethrin·compound A1 water-dispersible granules are obtained.

[0132] Formulation Example 7

[0133] Preparation of 35% chlorantraniliprole compound A4 microemulsion

[0134] According to the formulation requirements, by weight, 30 parts of chlorantraniliprole, 5 parts of compound A4, 10 parts of diphenylphenol polyoxyethylene (n18) ether formaldehyde condensate, 10 parts of agricultural emulsion 2201#, 5 parts of agricultural emulsion 700#, and 15 parts of cyclohexanone are added together to dissolve into a homogeneous oil phase. Then, 25 parts of water are added, and under high-speed stirring, the aqueous phase is added to the oil phase or the oil phase is added to the aqueous phase to form a well-dispersible 35% chlorantraniliprole·compound A4 microemulsion.

[0135] Formulation Example 8

[0136] Preparation of 40% Avermectin Compound A1 soluble concentrate

[0137] According to the formula requirements, by weight, 35 parts of abamectin, 5 parts of compound A1, 15 parts of agricultural emulsion 507#, 5 parts of agricultural emulsion 1601#, 6 parts of agricultural emulsion 100#, 12 parts of dimethylformamide, 15 parts of dimethyl sulfoxide, and 7 parts of methanol can be dissolved by heating in a hot water bath if necessary to obtain a 40% abamectin·compound A1 soluble concentrate.

[0138] Formulation Example 9

[0139] Preparation of 60% Carbendazim Compound A2 Wettable Powder

[0140] According to the formula requirements, by weight, 50 parts of carbendazim, 10 parts of compound A2, 2 parts of sodium dodecyl sulfate, 6 parts of sodium naphthol sulfonate formaldehyde condensate, 4 parts of sodium lignosulfonate, 5 parts of white carbon black, and 33 parts of bentonite are thoroughly mixed and then pulverized by an ultrafine pulverizer to obtain 60% carbendazim·compound A2 wettable powder.

[0141] Formulation Example 10

[0142] Preparation of 55% pyraclostrobin compound A3 emulsifiable concentrate

[0143] According to the formula requirements, add 45 parts of pyraclostrobin, 10 parts of compound A3, 7 parts of agricultural emulsion 0201B, 3 parts of agricultural emulsion NP-15, 2 parts of agricultural emulsion 700#, 12 parts of dimethylformamide, and 21 parts of xylene by weight, respectively, mix well, and if necessary, heat in a hot water bath to dissolve, to obtain 55% pyraclostrobin·compound A3 emulsifiable concentrate.

[0144] Formulation Example 11

[0145] Preparation of 35% Mancozeb Compound A4 Wettable Powder

[0146] According to the formula requirements, by weight, 30 parts of mancozeb, 5 parts of compound A4, 2 parts of sodium dodecyl sulfate, 6 parts of sodium naphthol sulfonate formaldehyde condensate, 4 parts of sodium lignosulfonate, 5 parts of white carbon black, and 48 parts of bentonite are thoroughly mixed and then pulverized by an ultrafine pulverizer to obtain 35% mancozeb·compound A4 wettable powder.

[0147] Formulation Example 12

[0148] Preparation of 40% Fluopyram·Compound A1 Wettable Powder

[0149] According to the formula requirements, by weight, 35 parts of fluopyram, 5 parts of compound A1, 2 parts of sodium dodecyl sulfate, 6 parts of sodium naphthol sulfonate formaldehyde condensate, 4 parts of sodium lignosulfonate, 5 parts of white carbon black, and 43 parts of bentonite are thoroughly mixed and then pulverized by an ultrafine pulverizer to obtain 40% fluopyram·compound A1 wettable powder.

[0150] Formulation Example 13

[0151] Preparation of 50% Chlorfluazuron·Compound A2 Suspension Formulation

[0152] According to the formula requirements, by weight, 40 parts of chlorfluazuron, 10 parts of compound A2, 3 parts of sodium lignosulfonate, 5 parts of sodium naphthalenesulfonate formaldehyde condensate, 2 parts of agricultural emulsion 1601#, 3 parts of agricultural emulsion 0201B, 0.1 parts of xanthan gum, 0.2 parts of silica, 5 parts of ethylene glycol, and 31.7 parts of water are added to a sand mill and ground into a fine powder to prepare a 50% chlorfluazuron·compound A2 suspension.

[0153] Example

[0154] Indoor bioactivity assay

[0155] Test subjects: Tetranychus cinnabarinus, adult mites, and sensitive strains kept indoors.

[0156] Test conditions: 25°C constant temperature incubator, relative humidity 60%, light intensity L:D = 14:10

[0157] Preparation of test solution: According to the experimental requirements, accurately weigh more than 50 mg of the test sample using an electronic analytical balance, dilute to the required concentration with acetone, add the acetone solution to a volumetric flask according to the calculation, add 0.1 wt% Tween 80 water to dilute and dilute to the required concentration to obtain the test solution.

[0158] Test method: After cutting the green bean seedlings, remove one true leaf and leave one true leaf. Add the seedlings to a hydroponic glass bottle. Inoculate the leaf with about 50-150 adult spider mites of the same size. Count the number of inoculated mites the next day. Use the Airbrush method to spray the test material with the pesticide solution. Spray 1.5 mL of pesticide solution for each treatment. Set up 3 blank control treatments.

[0159] After spraying and air drying, the treated test materials were placed in a constant-temperature observation room. The number of live mites was counted after 72 hours, and the mortality rate was calculated. The Bliss method was used for evaluation, and the theoretical mortality rate can be calculated using the following formula:

[0160] P = P m +P n (1-P m )

[0161] P m Pm represents the target mortality rate (%) of the first active component (active component a) at a concentration of m; Pn represents the target mortality rate (%) of the second active component (active component b) at a concentration of n.

[0162] In the following embodiments, if the actual mortality rate of the target is greater than the theoretical mortality rate P after the two active components are mixed at a certain concentration, it is determined that the two active components have a synergistic effect when used together at the set concentration; otherwise, they have an antagonistic effect.

[0163] Example 1

[0164] The synergistic effect of compounds A1 (I-53) and A9 (I-1202) on adult Tetranychus cinnabarin was tested when they were used in combination with two agents, spirodiclofen and spirodiclofen. The test results are shown in Table 1.

[0165] Table 1:

[0166]

[0167]

[0168]

[0169] Example 2

[0170] The synergistic effect of compounds A1 and A9 with etoxazole on adult Tetranychus cinnabarinus was tested. The test results are shown in Table 2.

[0171] Table 2:

[0172]

[0173]

[0174] Example 3

[0175] The synergistic effect of compounds A1 and A9 with propargite on adult Tetranychus carmine was tested. The test results are shown in Table 3.

[0176] Table 3:

[0177]

[0178]

[0179] Example 4

[0180] The synergistic effect of compounds A1 and A9 with etoxazole on adult Tetranychus cinnabarinus was tested. The test results are shown in Table 4.

[0181] Table 4:

[0182]

[0183]

[0184] Example 5

[0185] The synergistic effect of compounds A1 and A9 with avermectin on adult Tetranychus carmine was tested. The test results are shown in Table 5.

[0186] Table 5:

[0187]

[0188]

[0189] Example 6

[0190] The synergistic effect of compounds A1 and A9 with tetradifon on adult Tetranychus cinnabarin was tested. The test results are shown in Table 6.

[0191] Table 6:

[0192]

[0193]

[0194] Example 7

[0195] The synergistic effect of compounds A1 and A9 with thiamethoxam on adult Tetranychus cinnabarinus was tested. The test results are shown in Table 7.

[0196] Table 7:

[0197]

[0198]

[0199] The composition provided by this invention has the advantages of synergistic effect and broadened control spectrum, and can be used to control a variety of pests (especially mites) and plant diseases caused by a variety of fungi, bacteria, nematodes and viruses.

[0200] The preferred embodiments of the present invention have been described in detail above; however, the present invention is not limited thereto. Within the scope of the inventive concept, various simple modifications can be made to the technical solutions of the present invention, including combinations of various technical features in any other suitable manner. These simple modifications and combinations should also be considered as the content disclosed in the present invention and are all within the protection scope of the present invention.

Claims

1. A composition characterized in that, The composition comprises active component a and active component b, wherein the weight ratio of active component a to active component b is 150:1 to 1:150; The active component a includes compounds having the structures shown in Formula I-53 and / or Formula I-1202; 、 ； The active component b is selected from spirodiclofen, spirodiclofen, etoxazole, propargite, etoxazole, abamectin, tetradifon, or thiamethoxam.

2. The use of the composition according to claim 1 in the prevention and control of insect pests, mites or diseases.

3. Use according to claim 2, wherein, The composition is used to control insect pests, mites, or diseases by applying it directly or indirectly to the insects, mites, fungi, or their growth medium at an effective dose of 10-5000 grams per hectare.

4. The application of a composition in the control of mites, characterized in that, The composition comprises active component a and active component b, wherein active component a comprises a compound having the structure shown in formula I-53 and / or formula I-1202; and active component b is selected from tetradifon and / or thiamethoxam. 、 ； The weight ratio of active component a to active component b is 1:(5-30).

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