Biological information measuring device

Abstract

A biological information measuring device includes: a blood pressure measuring section that measures blood pressure of a subject, the blood pressure measuring section having a cuff that compresses a measured site of the subject, a pump that supplies gas into the cuff, an exhaust valve that adjusts discharge of the gas from the cuff, a pressure detecting section that detects a cuff pressure as a pressure in the cuff, a cuff pressure control section that controls the pump and the exhaust valve, and a blood pressure operation section that calculates the blood pressure of the subject; an electrocardiogram measuring section that measures an electrocardiogram waveform by processing an electrical signal acquired by a plurality of electrodes, the plurality of electrodes including an electrode provided on a side of the measured site of the cuff and capable of contacting a skin of the subject; and an electrocardiogram storage section that stores information of the measured electrocardiogram waveform in association with time, the biological information measuring device including an interval specifying section that specifies an interval of the information of the electrocardiogram waveform from the information of the electrocardiogram waveform stored in the electrocardiogram storage section based on a progress of the measurement of the blood pressure of the subject in parallel with the measurement of the electrocardiogram waveform.

Description

Technical Field

[0001] This invention relates to a biological information measuring device. Background Technology

[0002] A device as shown in Patent Document 1 is proposed as an apparatus for measuring electrocardiograms by adding an electrocardiogram measurement function to a conventional cuff compression blood pressure monitor.

[0003] Existing technical documents

[0004] Patent documents

[0005] Patent Document 1: Japanese Patent Application Publication No. 2014-36843 Summary of the Invention

[0006] The problem the invention aims to solve

[0007] However, in conventional configurations where electrocardiogram (ECG) measurements are performed when the cuff pressure is stable, the cuff pressure needs to change during blood pressure measurement, making it impossible to perform ECG and blood pressure measurements simultaneously. In particular, when ECG and blood pressure measurements are performed simultaneously, the following problems arise: initially, when the cuff pressure is insufficient, the contact between the body and electrodes—whether not in contact or suddenly transitioning from a very small portion of the electrode surface to full contact—is highly unstable. This results in significant noise in the electronic circuitry that acquires and amplifies the electrode signals, making it impossible to obtain the stable ECG waveform required for accurate diagnosis.

[0008] In view of the aforementioned problems, the object of the present invention is to provide a technique for measuring stable electrocardiogram waveforms in a biological information measuring device that simultaneously measures blood pressure and electrocardiogram waveforms.

[0009] Solution for solving the problem

[0010] To address the aforementioned problems, the present invention provides a biological information measuring device, which comprises:

[0011] A blood pressure measuring unit includes a cuff that compresses the measurement site of a subject, a pump that supplies gas into the cuff, an exhaust valve that adjusts the gas discharge from the cuff, a pressure detection unit that detects cuff pressure as the pressure inside the cuff, a cuff pressure control unit that controls the pump and the exhaust valve, and a blood pressure calculation unit that calculates the blood pressure of the subject.

[0012] An electrocardiogram (ECG) measurement unit processes electrical signals acquired through multiple electrodes to measure ECG waveforms; these electrodes are in contact with the skin of the subject.

[0013] An electrocardiogram (ECG) storage unit stores information about the measured ECG waveforms in a time-dependent manner.

[0014] The biological information measuring device is characterized in that...

[0015] The device includes an interval designation unit that, based on the measurement of the subject's blood pressure in parallel with the measurement of the electrocardiogram waveform, designates an interval of the electrocardiogram information from the information of the electrocardiogram stored in the electrocardiogram storage unit.

[0016] In a biometric device for measuring electrocardiogram (ECG) waveforms by processing electrical signals acquired from multiple electrodes, including electrodes located at the measurement site on the cuff, in parallel with blood pressure measurement (which involves controlling the pressure within the cuff at the measurement site), the contact state between the electrodes at the measurement site and the subject's skin may change due to variations in cuff pressure caused by the blood pressure measurement. In this invention, by providing an interval designation unit, it is possible to designate ECG waveforms acquired over time that are measured under conditions where the contact state between the subject's skin and the electrodes is consistent. This interval designation unit designates intervals of ECG waveform information based on the blood pressure measurement performed concurrently with the ECG waveform measurement, using ECG waveform information stored in the ECG storage unit in a time-dependent manner. Furthermore, by designating intervals where the contact state between the subject's skin and the electrodes is stable, it is also possible to designate intervals of ECG waveform information with low noise and high quality. By designating intervals of ECG waveform information in this way, stable ECG waveform information can be extracted, thus enabling stable ECG waveform measurements. Furthermore, the extracted electrocardiogram waveform information can be effectively used for various purposes such as disease diagnosis.

[0017] Furthermore, in this invention, the interval designation unit can employ various indicators as indicators representing the progress of blood pressure measurement of the subject, which is performed concurrently with the measurement of the electrocardiogram (ECG) waveform. That is, it can be configured to designate the interval of the ECG waveform information based on the cuff pressure during the blood pressure measurement. Alternatively, the interval designation unit can be configured to designate the interval of the ECG waveform information based on the time taken during the blood pressure measurement. Furthermore, it can be configured to include a pulse wave amplitude calculation unit that calculates the pulse wave amplitude based on the cuff pressure detected by the pressure detection unit, and the interval designation unit designates the interval of the ECG waveform information based on the pulse wave amplitude. In this way, stable ECG waveform measurement can be performed in a bio-information measuring device that calculates pulse wave amplitude to measure blood pressure information such as minimum and maximum blood pressure, as in the oscillometric method. Alternatively, the interval designation unit can be configured to designate the interval of the ECG waveform information based on the blood pressure of the subject calculated by the blood pressure calculation unit. It should be noted that, preferably, the calculated blood pressure includes at least one of the lowest blood pressure and the highest blood pressure.

[0018] Furthermore, in this invention, it can also be set as follows:

[0019] The blood pressure measuring unit measures the subject's blood pressure during at least one of the processes of increasing the pressure of the cuff and decreasing the pressure of the cuff.

[0020] In this way, stable electrocardiogram waveforms can be measured in both the bio-information measuring device with a blood pressure measuring unit that measures the subject's blood pressure during the pressurization process of increasing cuff pressure and the bio-information measuring device with a blood pressure measuring unit that measures the subject's blood pressure during the depressurization process of decreasing cuff pressure.

[0021] Invention Effects

[0022] According to the present invention, a technique is provided that enables stable measurement of electrocardiogram waveforms in a measuring device that simultaneously measures blood pressure and electrocardiogram waveforms. Attached Figure Description

[0023] Figure 1 This is a block diagram illustrating the general configuration of the biological information measuring device of Example 1.

[0024] Figure 2 This is a graph showing the progress of blood pressure and electrocardiogram measurements in Example 1, as well as the time-varying cuff pressure.

[0025] Figure 3 This is a graph showing the progress of blood pressure and electrocardiogram measurements in Example 2, as well as the time-varying changes in cuff pressure.

[0026] Figure 4 This is a graph showing the progress of blood pressure and electrocardiogram measurements in Example 3, as well as the time changes in cuff pressure and pulse wave amplitude.

[0027] Figure 5 This is a graph showing the progress of blood pressure and electrocardiogram measurements in Example 4, as well as the time changes in cuff pressure and pulse wave amplitude.

[0028] Figure 6 This is a graph showing the progress of blood pressure and electrocardiogram measurements in Example 5, as well as the time-varying changes in cuff pressure.

[0029] Figure 7 This is a graph showing the progress of blood pressure and electrocardiogram measurements in Example 6, as well as the time changes in cuff pressure and pulse wave amplitude.

[0030] Figure 8 This is a graph showing the progress of blood pressure and electrocardiogram measurements in Example 7, as well as the time-varying changes in cuff pressure.

[0031] Figure 9 This is a graph showing the progress of blood pressure and electrocardiogram measurements in Example 8, as well as the time-varying changes in cuff pressure.

[0032] Figure 10 This is a graph showing the progress of blood pressure and electrocardiogram measurements in Example 9, as well as the time changes in cuff pressure and pulse wave amplitude.

[0033] Figure 11 This is a graph showing the progress of blood pressure and electrocardiogram measurements in Example 10, as well as the time changes in cuff pressure and pulse wave amplitude.

[0034] Figure 12 This is a graph showing the progress of blood pressure and electrocardiogram measurements in Example 11, as well as the time-varying changes in cuff pressure.

[0035] Figure 13 This is a graph showing the progress of blood pressure and electrocardiogram measurements in Example 12, as well as the time changes in cuff pressure and pulse wave amplitude. Detailed Implementation

[0036] Hereinafter, specific embodiments of the present invention will be described based on the accompanying drawings. Unless otherwise specified, the dimensions, materials, shapes, and relative arrangements of the constituent components described in this embodiment are not intended to limit the scope of the invention to these specific details.

[0037] <Example 1>

[0038] Hereinafter, Embodiment 1 of the present invention will be described.

[0039] (Composition of a biological information measuring device)

[0040] Figure 1 This is a block diagram showing the general configuration of the biological information measuring device 100 of this embodiment. The biological information measuring device 100 mainly consists of an electrocardiogram detection unit 110, a blood pressure measuring mechanism unit 120, a control unit 130, an operation unit 140, and a display unit 150.

[0041] The electrocardiogram (ECG) detection unit 110 includes electrodes 111 and 112, and an ECG measurement circuit 113. Electrodes 111 and 112 are in contact with the subject's skin to detect electrical signals. The ECG measurement circuit 113 includes an amplifier that amplifies the electrical signals detected by electrodes 111 and 112, and an analog-to-digital conversion circuit (AD converter) that converts analog signals into digital signals. Here, regarding the electrodes used to detect ECG waveforms in contact with the subject's skin, an appropriate number of electrodes can be provided, not limited to electrodes 111 and 112. Here, at least one of electrodes 111 and 112 is provided on the measurement site side of the cuff 121 described later. Here, electrodes 111 and 112 correspond to the plurality of electrodes of the present invention that can contact the subject's skin. Furthermore, the ECG measurement circuit 113 and the ECG control unit 131 described later constitute the ECG measurement unit of the present invention.

[0042] The blood pressure measuring mechanism 120 includes a cuff 121, a pressure sensor 122, a pressurizing pump 123, a drive circuit 124, and an exhaust valve 125. The cuff 121 is a strip-shaped component with an internal pouch. The pressure sensor 122 measures the cuff pressure, which is the pressure within the cuff 121, and its output is sent to the blood pressure measuring control unit 134 (described later). The pressurizing pump 123 pressurizes the cuff 121 by supplying air into it. The drive circuit 124 drives the pressurizing pump 123 based on instructions from the blood pressure measuring control unit 134. The exhaust valve 125 adjusts the amount of air expelled from the cuff 121 based on instructions from the blood pressure measuring control unit 134. The cuff 121 is wrapped around the subject's wrist, upper arm, or other measurement area. Air is supplied to the cuff 121, with the exhaust valve 125 closed, from the pressurization pump 123, thereby pressurizing the cuff 121 and compressing the measurement area. After pressurizing to a predetermined pressure, the exhaust valve 125 is opened to expel the air from the cuff 121, thus depressurizing it. Here, the cuff 121, pressure sensor 122, pressurization pump 123, and exhaust valve 125 correspond to the cuff, pressure detection unit, pump, and exhaust valve of the present invention, respectively. Furthermore, air has been described as an example of the gas supplied to the cuff 121, but the method is not limited to this.

[0043] The control unit 130 may be configured, for example, as a microcontroller unit (MCU) having a CPU (Central Processing Unit) and a memory including main memory and auxiliary memory. The functions described later are implemented by reading the program stored in the auxiliary memory into the main memory and executing it in the CPU. The control unit 130 may also be configured as an application-specific integrated circuit (ASIC), a field-programmable gate array (FPGA), or the like.

[0044] The control unit 130 includes an electrocardiogram control unit 131, a storage unit 132, a symptom determination interval determination unit 133, a blood pressure measurement control unit 134, a pulse wave amplitude calculation unit 135, a blood pressure calculation unit 136, and a display control unit 137.

[0045] The electrocardiogram (ECG) control unit 131 performs prescribed calculations on the data acquired through electrodes 111 and 112 and processed by the ECG measurement circuit 113, thereby measuring the ECG waveform. The ECG waveform information measured by the ECG control unit 131 is stored in the storage unit 132 in a time-dependent manner. The symptom determination interval determination unit 133, based on information from the pulse wave amplitude calculation unit 135 or the blood pressure calculation unit 136 (described later), determines the symptom determination interval for extracting the portion of the ECG waveform information stored in the storage unit 132 that is used in symptom determination. Here, the storage unit 132 corresponds to the ECG storage unit of the present invention. Furthermore, the symptom determination interval determination unit corresponds to the interval designation unit of the present invention.

[0046] The blood pressure measurement and control unit 134 acquires cuff pressure information measured by the pressure sensor 122 and controls the drive circuit 124 and the exhaust valve 125. Based on the cuff pressure information acquired by the blood pressure measurement and control unit 134, the pulse wave amplitude calculation unit 135 calculates the pulse wave amplitude, and the blood pressure calculation unit 136 calculates the blood pressure, including the highest blood pressure (systolic blood pressure) and the lowest blood pressure (diastolic blood pressure). Here, blood pressure is measured using the oscillometric method. That is, during pressurization control (increasing cuff pressure) or depressurization control (decreasing cuff pressure), the pulse wave amplitude calculation unit 135 calculates the pulse wave amplitude obtained from the cuff pressure, and the blood pressure calculation unit 136 calculates the highest and lowest blood pressure based on the changes in the pulse wave amplitude calculated in this way. Information related to the blood pressure calculated by the blood pressure calculation unit 136 is sent to the display control unit 137 of the control display unit 150. In the display control unit 137, image information including blood pressure-related information is generated and displayed on the display unit 150. Here, the blood pressure measurement control unit 134, the pulse wave amplitude calculation unit 135, and the blood pressure calculation unit 136 correspond to the cuff pressure control unit, the pulse wave amplitude calculation unit, and the blood pressure calculation unit of the present invention, respectively. Furthermore, the blood pressure measurement unit of the present invention is configured to include a cuff 121, a pressure sensor 122, a pressure pump 123, an exhaust valve 125, a blood pressure measurement control unit 134, a pulse wave amplitude calculation unit 135, and a blood pressure calculation unit 136.

[0047] The operation unit 140 includes operation indicator units such as buttons and switches, and accepts instructions to start blood pressure and electrocardiogram measurements, as well as various setting inputs. The display unit 150 includes, for example, an image display unit such as an LCD screen, displaying measurement information such as maximum blood pressure, minimum blood pressure, pulse, and electrocardiogram waveform, operation instructions, and notifications indicating abnormalities, among other information. It can be configured to display the information needed to determine the symptom assessment range on the display unit 150, allowing the subject to select and set it via the operation unit 140, or it can be configured to have default values ​​set by the operator at the factory.

[0048] Figure 2 This graph illustrates the progress of blood pressure and electrocardiogram (ECG) measurements and the change in cuff pressure over time when ECG and blood pressure measurements are performed simultaneously. Here, blood pressure is measured during the inflation process (inflation process). Starting from the measurement start time T0, the exhaust valve 125 is closed, and the pressurization pump 123 is activated, gradually increasing the cuff pressure. At the time Tp when the cuff pressure reaches the specified pressure, the pressurization pump 123 stops, and the blood pressure measurement ends. Then, the exhaust valve 125 opens, rapidly expelling air from the cuff 121, and the cuff pressure decreases sharply.

[0049] Here, blood pressure and electrocardiogram (ECG) waveforms are measured simultaneously. Therefore, blood pressure measurement and ECG waveform measurement are performed in parallel. From the measurement start time T0, the ECG waveform is continuously measured while the cuff 121 is inflated. However, based on various indicators representing the progress of blood pressure measurement, the symptom determination interval 133 determines the symptom determination interval from the ECG waveform information measured over time, thereby specifying a certain interval (time range). By specifying a certain interval of ECG waveform information based on indicators representing the progress of blood pressure measurement, the ECG waveform can be extracted when the subject's skin is in a certain contact state with electrodes 111 and 112, thus enabling stable ECG waveform measurement. Examples of such a fixed interval include those suitable for symptom determination that allow for stable ECG waveform measurement, but appropriate intervals can also be specified according to the purpose of ECG waveform processing and utilization.

[0050] In the method for determining the symptom assessment interval in Example 1, such as Figure 2 As shown, the time point Ds1 when the cuff pressure reaches or exceeds the specified pressure Ps1 is set as the starting point of the symptom assessment interval. For the symptom assessment interval, only the starting point needs to be determined. In this case, for example, the end time Tp of the pressurization process can also be set as the end point of the symptom assessment interval. Alternatively, the time point De1 when the cuff pressure reaches or exceeds the specified pressure Pe1 can also be set as the end point of the symptom assessment interval.

[0051] <Example 2>

[0052] Hereinafter, Example 2 will be described. Since the method for determining the symptom determination interval is the same as in Example 1, the description of the structure of the biological information measuring device, etc., will be omitted.

[0053] Figure 3 This is a graph showing the progress of blood pressure and electrocardiogram measurements and the time-varying changes in cuff pressure when electrocardiogram and blood pressure measurements are performed simultaneously.

[0054] Here, the starting point of the symptom assessment interval is set as Ds2, which is the time point elapsed from the start time T0 of the blood pressure and electrocardiogram measurements over a specified time T21. For the symptom assessment interval, only the starting point needs to be determined. For example, the end time Tp of the pressurization process can also be determined as the end point. Alternatively, the end point of the symptom assessment interval can be set as De2, which is the time point elapsed from the time point Ds2 (the time point elapsed from the start of the measurement over time T21) over a further specified time T22.

[0055] By determining the symptom range in this way, stable electrocardiogram measurements can be performed.

[0056] <Example 3>

[0057] Hereinafter, Example 3 will be described. Since the method for determining the symptom determination interval is the same as in Example 1, the description of the structure of the biological information measuring device, etc., will be omitted.

[0058] Figure 4 This is a graph showing the progress of blood pressure and electrocardiogram measurements when electrocardiogram and blood pressure measurements are performed simultaneously, as well as the time changes in cuff pressure and pulse wave amplitude.

[0059] Here, the time point Ds3 when the pulse wave amplitude reaches or exceeds the specified value As3 is set as the starting point of the symptom assessment interval. For the symptom assessment interval, only the starting point needs to be determined. In this case, for example, the end time Tp of the compression process can also be set as the ending point. Alternatively, the time point De3 when the cuff pressure is higher than the pressure Ps3 when the pulse wave amplitude reaches or exceeds the specified value As3 and the pulse wave amplitude falls below the specified value Ae3 can also be set as the ending point of the symptom assessment interval.

[0060] By determining the symptom range in this way, stable electrocardiogram measurements can be performed.

[0061] <Example 4>

[0062] Hereinafter, Example 4 will be described. Since the method for determining the symptom determination interval is the same as in Example 1, the description of the structure of the biological information measuring device, etc., will be omitted.

[0063] Figure 5 This is a graph showing the progress of blood pressure and electrocardiogram measurements when electrocardiogram and blood pressure measurements are performed simultaneously, as well as the time changes in cuff pressure and pulse wave amplitude.

[0064] Here, the starting point of the symptom assessment interval is defined as the time point Ds4 where the pulse wave amplitude is above and continues to be above the specified value As4. For the symptom assessment interval, only the starting point needs to be determined. For example, the end time point Tp of the compression process can also be defined as the end point. Alternatively, the end point of the symptom assessment interval can be defined as the time point De4 where the cuff pressure is higher than the pressure Ps4 at the time point Ds4 where the pulse wave amplitude is above and continues to be above the specified value As4, and the pulse wave amplitude is below the specified value Ae4 where the pulse wave amplitude continues to be below the specified value Ae4.

[0065] By determining the symptom range in this way, stable electrocardiogram measurements can be performed.

[0066] <Example 5>

[0067] Hereinafter, Example 5 will be described. Since the method for determining the symptom determination interval is the same as in Example 1, the description of the structure of the biological information measuring device, etc., will be omitted.

[0068] Figure 6 This is a graph showing the progress of blood pressure and electrocardiogram measurements and the time-varying changes in cuff pressure when electrocardiogram and blood pressure measurements are performed simultaneously.

[0069] Here, the interval between the time points at which the lowest blood pressure Dp5 and the highest blood pressure Sp5 are detected in the blood pressure measurement is determined as the symptom judgment interval. Specifically, the interval between the time point Ds5 before TD5 when the lowest blood pressure Dp5 is detected and the time point De5 after TS5 when the highest blood pressure Sp5 is detected is determined as the symptom judgment interval.

[0070] By determining the symptom range in this way, stable electrocardiogram measurements can be performed.

[0071] <Example 6>

[0072] Hereinafter, Example 6 will be described. Since the method for determining the symptom determination interval is the same as in Example 1, the description of the structure of the biological information measuring device, etc., will be omitted.

[0073] Figure 7 This is a graph showing the progress of blood pressure and electrocardiogram measurements when electrocardiogram and blood pressure measurements are performed simultaneously, as well as the time changes in cuff pressure and pulse wave amplitude.

[0074] Here, starting with a specific characteristic of the pulse wave amplitude, the predetermined time or pressure before and after it is defined as the symptom assessment interval. Although various characteristic quantities can be selected as specific characteristics of the pulse wave amplitude, Figure 7 In the example shown, the maximum amplitude is set as the characteristic quantity. Starting from the time point T6 when the pulse wave amplitude reaches its maximum, the time point Ds6 representing the amount of time Tb6 backwards from this point is set as the starting point of the symptom assessment interval, and the time point De6 representing the amount of time Ta6 elapsed from time point T6 is set as the ending point of the symptom assessment interval. Alternatively, starting from the time point T6 when the pulse wave amplitude reaches its maximum, the time point where the cuff pressure becomes a value that is a specified amount lower than the cuff pressure at time point T6 is set as the starting point of the symptom assessment interval, and the time point where the cuff pressure becomes a value that is a specified amount higher than the cuff pressure at time point T6 is set as the ending point of the symptom assessment interval.

[0075] By determining the symptom range in this way, stable electrocardiogram measurements can be performed.

[0076] <Example 7>

[0077] Hereinafter, Example 7 will be described. Since the method for determining the symptom assessment interval is the same as in Example 1, the configuration of the biometric information measuring device will be omitted. In Examples 1 to 6, the method for determining the symptom assessment interval was described in relation to measuring blood pressure during the inflation of the cuff. In the oscillometric method, by closing the exhaust valve 125 and driving the pressurization pump 123 to supply air to the cuff 121 to pressurize it to a predetermined pressure, and by adjusting the opening of the exhaust valve 125 to gradually expel air, blood pressure can also be measured during the decompression process (decompression process). In the following examples, the method for determining the symptom assessment interval will be described in relation to measuring blood pressure during the decompression process of the cuff.

[0078] Figure 8 This graph illustrates the progress of blood pressure and electrocardiogram (ECG) measurements and the time-varying changes in cuff pressure when ECG and blood pressure measurements are performed simultaneously. Here, as described above, blood pressure is measured during the decompression of the cuff. Starting from the measurement start time T0, the exhaust valve 125 is closed, and the pressurization pump 123 is activated, causing the cuff pressure to increase rapidly. At the time Tp0 when the cuff pressure reaches the specified pressure, the pressurization pump 123 is stopped. Then, with the pressurization pump 123 stopped, the opening of the exhaust valve 125 is controlled to gradually expel air from the cuff 121, causing the cuff pressure to gradually decrease.

[0079] The electrocardiogram waveform is continuously measured from the measurement start time point T0, but the symptom determination interval determination unit 133 determines the symptom determination interval as a suitable interval for symptom determination that can measure a stable electrocardiogram waveform.

[0080] The method for determining the symptom assessment interval in Example 7 will be explained. For example... Figure 8 As shown, the starting point of the symptom assessment interval is set at the time point Ds7 when the cuff pressure, which is gradually reduced to a predetermined pressure Ps7, falls below that pressure. For the symptom assessment interval, only the starting point needs to be determined. In this case, for example, the ending time point Tp of the blood pressure measurement can also be set as the ending point of the symptom assessment interval. Alternatively, the ending point of the symptom assessment interval can be set at the time point De7 when the cuff pressure falls below the predetermined pressure Pe7.

[0081] By determining the symptom range in this way, stable electrocardiogram measurements can be performed.

[0082] <Example 8>

[0083] Hereinafter, Example 8 will be described. Since the method for determining the symptom determination interval is the same as in Example 1, the description of the structure of the biological information measuring device, etc., will be omitted.

[0084] Figure 9 This is a graph showing the progress of blood pressure and electrocardiogram measurements and the time-varying changes in cuff pressure when electrocardiogram and blood pressure measurements are performed simultaneously.

[0085] Here, the starting point of the symptom assessment interval is set as Ds8, which is the time point elapsed for a predetermined time T81 from the start time T0 of the blood pressure and electrocardiogram measurements. For the symptom assessment interval, only the starting point needs to be determined. For example, the end time Tp of the blood pressure measurement can also be set as the end point of the symptom assessment interval. Alternatively, the end point of the symptom assessment interval can be set as De8, which is the time point further elapsed for a predetermined time T82 from the time point Ds8, which is the time point elapsed for a predetermined time T81 from the start of the measurement.

[0086] By determining the symptom range in this way, stable electrocardiogram measurements can be performed.

[0087] <Example 9>

[0088] Hereinafter, Example 9 will be described. Since the method for determining the symptom determination interval is the same as in Example 1, the description of the structure of the biological information measuring device, etc., will be omitted.

[0089] Figure 10 This is a graph showing the progress of blood pressure and electrocardiogram measurements when electrocardiogram and blood pressure measurements are performed simultaneously, as well as the time changes in cuff pressure and pulse wave amplitude.

[0090] Here, the time point Ds9 when the pulse wave amplitude reaches or exceeds the specified value As9 is set as the starting point of the symptom assessment interval. For the symptom assessment interval, only the starting point needs to be determined. For example, the end time point Tp of the blood pressure measurement can also be set as the end point of the symptom assessment interval. Alternatively, the time point De9 when the cuff pressure is lower than the pressure Ps9 when the pulse wave amplitude reaches or exceeds the specified value As9, and the pulse wave amplitude falls below the specified value Ae9, can also be set as the end point of the symptom assessment interval.

[0091] By determining the symptom range in this way, stable electrocardiogram measurements can be performed.

[0092] <Example 10>

[0093] Hereinafter, Example 10 will be described. Since the method for determining the symptom determination interval is the same as in Example 1, the description of the structure of the biological information measuring device, etc., will be omitted.

[0094] Figure 11 This is a graph showing the progress of blood pressure and electrocardiogram measurements when electrocardiogram and blood pressure measurements are performed simultaneously, as well as the time changes in cuff pressure and pulse wave amplitude.

[0095] Here, the starting point of the symptom assessment interval is defined as the time point Ds10 where the pulse wave amplitude is at or above the specified value As10 and where the pulse wave amplitude is continuously at or above the specified value As10. For the symptom assessment interval, only the starting point needs to be determined. For example, the end time point Tp of the blood pressure measurement can also be defined as the end point of the symptom assessment interval. Alternatively, the end point of the symptom assessment interval can be defined as the time point De10 where, for the time point De10, the cuff pressure is lower than the pressure Ps10 at the time point Ds10 where the pulse wave amplitude is at or above the specified value As10 and where the pulse wave amplitude is continuously at or below the specified value Ae10.

[0096] By determining the symptom range in this way, stable electrocardiogram measurements can be performed.

[0097] <Example 11>

[0098] Hereinafter, Example 11 will be described. Since the method for determining the symptom determination interval is the same as in Example 1, the description of the structure of the biological information measuring device, etc., will be omitted.

[0099] Figure 12 This is a graph showing the progress of blood pressure and electrocardiogram measurements and the time-varying changes in cuff pressure when electrocardiogram and blood pressure measurements are performed simultaneously.

[0100] Here, the interval including the time points at which the highest blood pressure Sp11 and the lowest blood pressure Dp11 are detected in the blood pressure measurement is determined as the symptom judgment interval. That is, the interval is determined as the time point Ds11 before TS11 when the highest blood pressure Sp11 is detected, and the time point De11 after TD11 when the lowest blood pressure Dp11 is detected, which is set as the end point.

[0101] By determining the symptom range in this way, stable electrocardiogram measurements can be performed.

[0102] <Example 12>

[0103] Hereinafter, Example 12 will be described. Since the method for determining the symptom determination interval is the same as in Example 1, the description of the structure of the biological information measuring device, etc., will be omitted.

[0104] Figure 13 This is a graph showing the progress of blood pressure and electrocardiogram measurements when electrocardiogram and blood pressure measurements are performed simultaneously, as well as the time changes in cuff pressure and pulse wave amplitude.

[0105] Here, starting with a specific characteristic of the pulse wave amplitude, the predetermined time or pressure before and after it is defined as the symptom assessment interval. Although various characteristic quantities can be selected as specific characteristics of the pulse wave amplitude, Figure 13 In the example shown, the maximum amplitude is set as the characteristic quantity. Starting from the time point T12 when the pulse wave amplitude reaches its maximum, the time point Ds12 representing a time retracement of Tb12 from this point is set as the starting point of the symptom assessment interval, and the time point De12 representing a time elapsed from time point T12 over time Ta12 is set as the ending point of the symptom assessment interval. Alternatively, starting from the time point T12 when the pulse wave amplitude reaches its maximum, the time point where the cuff pressure is a value lower than the cuff pressure at time point T12 is set as the starting point of the symptom assessment interval, and the time point where the cuff pressure is a value higher than the cuff pressure at time point T12 is set as the ending point of the symptom assessment interval.

[0106] By determining the symptom range in this way, stable electrocardiogram measurements can be performed.

[0107] Explanation of reference numerals in the attached figures

[0108] 100: Organism information measuring device;

[0109] 111, 112: Electrodes;

[0110] 113: Electrocardiogram (ECG) measurement circuit;

[0111] 121: Cuffs;

[0112] 122: Pressure sensor;

[0113] 123: Pressure pump;

[0114] 124: Drive circuit;

[0115] 125: Exhaust valve;

[0116] 131: Electrocardiogram Control Unit;

[0117] 132: Storage Department;

[0118] 133: Disease diagnosis interval determination section;

[0119] 134: Blood Pressure Measurement and Control Unit;

[0120] 135: Pulse wave amplitude calculation unit;

[0121] 136: Blood Pressure Calculation Department.

Claims

1. A biological information measuring device, the biological information measuring device comprising: The blood pressure measuring unit includes a cuff that compresses the measurement site of a subject, a pump that supplies gas into the cuff, an exhaust valve that adjusts the gas discharge from the cuff, a pressure detection unit that detects cuff pressure as the pressure inside the cuff, a cuff pressure control unit that controls the pump and the exhaust valve, and a blood pressure calculation unit that calculates the blood pressure of the subject. The blood pressure measuring unit measures the blood pressure of the subject during at least one of a pressurization process that increases the cuff pressure and a depressurization process that decreases the cuff pressure. An electrocardiogram (ECG) measurement unit processes electrical signals acquired through multiple electrodes to measure ECG waveforms, wherein the multiple electrodes are in contact with the skin of the subject. An electrocardiogram (ECG) storage unit stores information about the measured ECG waveform in a time-dependent manner; as well as The pulse wave amplitude calculation unit calculates the pulse wave amplitude based on the cuff pressure detected by the pressure detection unit. The biological information measuring device is characterized in that... The device includes an interval designation unit that, based on the measurement of the subject's blood pressure in parallel with the measurement of the electrocardiogram waveform, during the inflation or deflation process, designates an interval of information of the electrocardiogram waveform stored in the electrocardiogram storage unit based on the cuff pressure during the blood pressure measurement, the time traveled during the blood pressure measurement, the pulse wave amplitude, or the subject's blood pressure.

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