Use of a substituted benzamide isoxazoline compound for the control of lepidopteran pests

Abstract

This invention relates to the use of a substituted benzamide isoxazoline compound for the control of Thysanoptera pests, wherein the substituted benzamide isoxazoline compound is of formula (I): The compound of formula (I) has excellent control effect on thymidopterygian pests and can effectively reduce the occurrence of viral diseases in host plants, and is safe for host plants.

Description

Use of a substituted benzamide isoxazoline compound for the control of thaliana pests Technical Field

[0001] This invention belongs to the field of pesticide technology, specifically relating to the use of a substituted benzamide isoxazoline compound for the control of tsioptera pests. Background Technology

[0002] Thysanoptera pests are characterized by short developmental periods, significant generational overlap, high reproductive rates, and parthenogenesis, making them typical pests susceptible to outbreaks and widespread damage. Although research on the biological control of thysanoptera pests has a history of over a century, no breakthroughs have been achieved in field applications. Thysanoptera pests have a wide host range, causing direct damage to host plants through feeding. Mild damage includes leaf spots, yellowing and curling, or scarring on fruit; severe damage leads to flower and fruit drop or even the death of the entire plant. Some species can also transmit plant viruses, resulting in even more serious economic losses.

[0003] Common methods for controlling tsioptera pests include physical control, biological control, control based on host plant resistance, and chemical control. Chemical control is currently the primary method for controlling tsioptera pests; however, with the widespread use of insecticides, tsioptera pests have developed resistance to many of them. This resistance inevitably forces farmers to increase pesticide application rates to achieve the same control effect, leading to increased pesticide residues and environmental pollution. Given the severe losses to agricultural production caused by tsioptera pests and the rapid development of their resistance, it is essential to screen for highly effective, low-toxicity pesticides that can delay the development of resistance in tsioptera pests.

[0004] The applicant discovered in its research on compounds of formula I that compounds of formula I, or combinations thereof, or mixtures thereof, can effectively control thymidopterygian pests and effectively reduce the occurrence of plant viral diseases, thus having unexpected application value. Summary of the Invention

[0005] Based on the above, the purpose of this invention is to provide a substituted benzamide isoxazoline compound for the control of tsioptera pests, especially for the nymphs and adults of tsioptera pests, which has a significant control effect.

[0006] To achieve the above objectives, the present invention adopts the following technical solution: the use of a substituted benzamide isoxazoline compound for the control of tsioptera pests, wherein the substituted benzamide isoxazoline compound is a compound of formula (I):

[0007]

[0008] Furthermore, the order Thysanoptera is further divided into the suborders Tubulifera Haliday and Terebrantia Haliday;

[0009] Furthermore, the suborder Phlaeothripidae includes Phlaeothripidae Uzel, dolothripinae Bagnall, and Phlaeothripinae Uzel.

[0010] Furthermore, the suborder Conodontia includes the families Aeolothripidae Uzel, Fauriellidae Priesner, Hemithripidae Bagnall, Heterothripidae Bagnall, Kerataothripidae Sharov, Liassothripidae Priesner, Melanthripidae Bagnall, Merothripidae Hood, Moundthripidae Nel, Stenurothripidae Bagnall, and Thripidae Stevens.

[0011] Furthermore, the aforementioned Thysanoptera pests include: palm thrips, tobacco thrips, tobacco brown thrips, alfalfa flower thrips, western flower thrips, cereal thrips, greenhouse thrips, hooked thrips, hard thrips species, citrus hard thrips, citrus thrips, tea yellow thrips, flower thrips, and rice thrips.

[0012] Furthermore, the Thripidae family includes tobacco thrips, rice thrips, greenhouse thrips, western flower thrips, tea yellow thrips, and palm thrips;

[0013] Furthermore, the host plant of the Thysanoptera pests is a crop, which includes one or more of the following: grains, vegetables, fruits, nuts, sugar crops, oil crops, beverage crops, seasoning crops, forage crops, and medicinal plants.

[0014] Furthermore, the crops mentioned include Solanaceae, Cucurbitaceae, Fabaceae, Brassicaceae, etc.

[0015] A method for controlling tsioptera pests, comprising applying an effective amount of a substituted benzamide isoxazoline compound or a combination thereof or a mixture thereof to the tsioptera pests to be controlled or to the medium in which they grow.

[0016] Furthermore, the composition containing formula (I) comprises a compound of formula (I) and an agriculturally permitted pesticide adjuvant;

[0017] Furthermore, the mixture containing formula (I) includes formula (I) compound, additional active ingredients, and agriculturally permitted pesticide adjuvants;

[0018] Furthermore, the other active ingredient is selected from one or more of the following: insecticides, acaricides, fungicides, nematicides, herbicides, and plant growth regulators.

[0019] Furthermore, the insecticides and acaricides mentioned are selected from alanycarb, aldicarb, aldoxycarb, allyxycarb, aminocarb, bendiocarb, benfuracarb, bufencarb, butacarb, butocarboxim, butoxycarboxim, carbaryl, carbofuran, carbosulfan, and dichlorvos. Cloethocarb, Dimetilan, Ethiofencarb, Fenobucarb, Fenothiocarb, Fenooxycarb, Formetate, Furathiocarb, Isoprocarb, Metam-Sodium, Methiocarb, Methomyl, Metolcarb, Oxamyl, Pirimicarb, and Pyridaben Romecarb, propoxur, thiofanox, trimethacarb, XMC, xylylcarb, triazamate, acephate, azamethiphos, azinphos (-methyl, -ethyl), bromophos-ethyl, bromfenvinfos (-methyl), butathiofos. Cadusafos, carbophenothion, chlorethoxyfos, chlorfenvinphos, chlormephos, coumaphos, cyanofenphos, cyanophos, chlorfenvinphos, demeton-S-methyl, demeton-S-methylsulfone, dialifos, diazinonDichlorvos / DDVP, didrotophos, dimethoate, dimethylvinphos, dioxabenzofos, disulfoton, EPN, ethion, ethoprophos, etrimfos, famphur, fenamiphos, fenitrothion rothion, fensulfothion, fenthion, flupyrazofos, fonofos, formothion, fosmethilan, fosthiazate, heptenophos, iodofenphos, iprobenfos, isazofos, isofenphos, isopropyl salicylate O-salicylate), isoxathion, malathion, mecarbam, methacrifos, methamidophos, methidathion, mevinphos, monocrotophos, naled, omethoate, oxydemeton-methyl, parathion (-methyl / -ethyl), phenthoate, phorate, p-methoxam hosalone, phosmet, phosphamidon, phosphocarb, phoxim, pirimiphos (-methyl / -ethyl), profenofos, propaphos, propetamphos, prothiofos, prothoate, pyraclofos, pyridaphenthion, pyridathion, quinalphos, sebufosThe following pesticides are used to control pyrethroids: sulfotep, sulprofos, tebupirimfos, temephos, terbufos, tetrachlorvinphos, thiometon, triazophos, trichlorfon, vamidothion, acridine lactate, d-cis-trans, d-trans, beta-cyfluthrin, and bifenthrin. Bioallethrin, bioallethrin-S-cyclopentyl isomer, bioethanomethrin, biopermethrin, bioresmethrin, chlovaporthrin, cis-cypermethrin, cis-resmethrin, cis-permethrin, clocythrin, and pyrethrum. Esters (cycloprothrin), cyfluthrin, cyhalothrin, cyphenothrin, eflusilanate, empenthrin (1R-isomer), esfenvalerate, etofenprox, fenfluthrin, fenpropathrin, fenpyrithrin, fenvalerate, flubrocythrinat e) Flucythrinate, flufenprox, flumethrin, fluvalinate, fubfenprox, gamma-cyhalothrin, imiprothrin, kadethrin, lambda-cyhalothrin, metofluthrin, permethrin (cis-, trans-), phenoxy ...Prallethrin, profluthrin, protrifenbute, pyresmethrin, pyrethrin, resmethrin, RU15525, silafluofen, tau-fluvalinate, tefluthrin, terallethrin, pyrethrin (1R isomer), tralomethrin, transfluthrin, ZXI 8901, pyrethrins (pyrethrum), b) DDT, c) oxadiazines, indoxacarb, metaflumizone, acetamiprid, AKD 1022. Dinotefuran, Imidaclothiz, Nitenpyram, Nithiazine, Thiacloprid, Nicotine, Bensultap, Cartap, Spinosyns, Camphechlor, Chlordane, Endosulfan, γ-HCH, HCH, Heptachlor, Lindane, Methoxychlor, Acetonitrile, Pyrafluprole, Pyriprole, Vaniliprole, Emamectin Ivermectin, lepimectin, milkemycin, diofenolan, epofenonane, fenoxycarb, hydroprene, kinoprene, methoprene, pyriproxifen, triprene, chromafenozide, halofenozide, methoxyfenozide, tebufenozide, bistrifluron, chlofluazuron, diflubenzuronFluazuron, flucycloxuron, flufenoxuron, hexaflumuron, novaluron, noviflumuron, penfluron, teflubenzuron, buprofezin, cyromazine, diafenthiuron, azocyclotin, cyhexatin, fenbutatin-oxide, chlorofenapyr, binapacyrl, and difenoconazole. (dinobuton), dinocap, DNOC, meptyldinocap, fenazaquin, fenpyroximate, pyrimidifen, pyridaben, tebufenpyrad, tolfenpyrad, or hydramethylnon, dicofol, rotenone, acequinocyl, fluacrypyrim, Bacillus thuringiensis subsp. Israel The following are listed as subspecies: *Bacillus israelensis*, *Bacillus sphaericus*, *Bacillus thuringiensis* subspecies *aizawai*, *Bacillus thuringiensis* subspecies *kurstaki*, *Bacillus thuringiensis* subspecies *tenebrionis*, Cry1Ab, Cry1Ac, Cry1Fa, Cry2Ab, mCry3A, Cry3Ab, Cry3Bb, Cry34 / 35Ab1, spirodiclofen, spiromesifen, spirotetramat, amitraz, propargite, thiocyclam hydrogen oxalate, and thiosultap-sodium.Azadirachtin, Bacillus spec., Beauveria spec., codlemone, Metarrhizium spec., Paecilomyces spec., thuringiensin, Verticillium spec., aluminum phosphide, methyl bromide, sulfuryl fluoride Fluoride, cryolite, flonicamid, pymetrozine, clofentezine, etoxazole, hexythiazox, amidoflumet, benclothiaz, benzoximate, bifenazate, bromopropylate, buprofezin, chinomethionat, chlorodimeform, chlorobenzila te), chloropicrin, clothiazoben, cycloprene, cyflumetofen, dicyclanil, fenoxacrim, fentrifanil, flubenzimine, flufenerim, flutenzin, gossyplure, hydramethylnone, japonicilure, metoxadiazone, petroleum, piperonylbutoxide, potassium oleate oleate), pyridalyl, sulfluramid, tetradifon, tetrasul, triarathene, verbutin, flufenoxuron, pyridaben, etoxazole, abamectin, emamectin benzoate, etoxazole, propargite, lufenuron, lambda-cyhalothrin, spirodiclofen, trifluralin, pyrimethanil, flufenoxuron, spirodiclofen, acetamiprid, fenpyroximate, benzylfenoxuron, mibamectin, fipronil, pyridabenOne or more of the following: flupentiofenox, acynonapyr, pyflubumide, vaniliprole, sulfiflumin, and thiamethoxam;

[0020] Furthermore, the bactericide is selected from the following: benalaxyl, benalaxyl-M, metalaxyl, metalaxyl-M, oxadixyl, furaxyl, furaxyl-M, 4-dodecyl-2,6-dimethylmorpholine, dodine, guazatine, iminoctadine, dodemorph, fenpropimorph, tridemorpholine. demorph, fenpropidin, buthiuron, spiroxamine, cyprodinil, pyrimethanil, mepanipyrim, benomyl, carbendazim, thiabendazole, fuberidazole, bitertanol, bromuconazole, cyproconazole, difenoconazole (d ifenoconazole, dinitroconazole, fenbuconazole, fluquinconazole, flusilazole, hexaconazole, myclobutanil, penconazole, propiconazole, prothioconazole, tebuconazole, triadimefon, epoxiconazole, fluconazole Triafol, imibenconazole, ipconazole, metconazole, simeconazole, tetraconazole, triadimenol, triticonazole, azaconazole, tricyclazole, imazalil, pefurazoate, prochloraz, triflumizole, ferbamSodium mancozeb, mancozeb, metiram, thiram, zineb, propineb, polycarbamate, ziram, metam, Bordeaux mixture, copper acetate, copper oxychloride, basic copper sulfate Basic, Captafol, Captan, Folpet, Iprodione, Procymidone, Vinclozolin, Dichlofluanid, Ametoctradin, Azoxystrobin, Coumoxystrobin, Famoxadone, Dimoxystrobin, Kresoximmethyl, Metominostrobin, Orysastrobin, Picoxystrobin, Trifloxystrobin, Pyracostrobin, Pyrametostrobin, Pyraoxystrobin, Pyribencarb, Benthiavalicarb, Propamocarb Hydrochloride, boscalid, isopyrazam, bixafen, penflufen, sedaxane, fluopyram, flunindapyr, bupirimate, carboxin, oxycarboxin, chloromethoxybenzene, chloronitrobenzene, tetrachloronitrobenzene, tolclofosmethyl, carpropamid, chlorothalonil, cyflufenamid, cymoxanil, fluopyram, zoxamid, flutolanilIsotianil, silthiopham, tiadinil, fluoxastrobin, triazoxide, dimethomorph, flumetover, flumorph, dithianon, edifenphos, iprobenfos, iprovalicarb, valifenalate, thifluzamide, ethab oxam), fenarimol, ethirimol, fluxapyroxad, furametpyr, penthiopyrad, flubeneteram, benzovindiflupyr, pydiflumetofen, diethofencarb, diclocymet, mepronil, fenfurame, fenamid One), fenhexamid, fluazinam, fludioxonil, feniclonil, fludioxonil, flusulfamide, triforne, cycloheximide, griseofulvin, kasugamycin, natamycin, polyoxin, streptomycin, validamycin, midomycin diomycin, polyoxin, azadirachtin, tetramycin, kasugamycin, ningnanmycin, tolylfluanid, mandipropamid, fenoxanil, metrafenone, fenpyrazamine, ferimzone, flutianil, fosetylaluminum, fosthiazate, pyrazophosOne or more of the following fungicides: hymexazol, oxolini cacid, phthalide, pencycuron, proquinazid, metrafenone, pyroquilon, quinoxyfen, amisulbrom, acibenzolar Smethyl, isoprothiolane, terbufos, octothiazolinone, cyazofamid, dazomet, silthiofam, thiophanate-methyl, myclozolin, anilazine, nuarimol, pyrifenox, probenazole, and diclomezine;

[0021] Furthermore, the herbicide is selected from acetochlor, acifluorfen, acifluorfen-sodium, aclonifen, alachlor, allidochlor, alloxydim, alloxydim-sodium, ametryn, amicabazone, amidochlor, amidosulfuron, aminocyclopyrachlor, aminocyclopyrachlor-potassium, aminocyclopyrachlor-methyl, aminopyralid, amitrol, and ammonium sulfate. Sulfamate, Ailofos, Asulam, Atrazine, Azafenidin, Azimsulfuron, Beflubutamid, Benazolin, Benazolin-ethyl, Benfluralin, Benfuresate, Bensulfuron-methyl, Bensulide, Bentazone, Benbicyclon, Benfenap, Bicyclopyrone Bifenox, bilanafos, bilanafos-sodium, bispyribac, bispyribac-sodium, bromacil, bromobutide, bromofenoxim, bromoxynil, bromoxynil-potassium, bromoxynil-heptanoate, bromoxynil-octanoate, bromoxynil-butyrate, busoxinone, butachlorButafenacil, butamifos, butenachlor, butralin, butroxydim, butylate, cafenstrole, carbetamide, carfentrazone-ethyl, chloramben, chlorbromuron, chlorfenac, chlorfenac-sodi um), oat ester (chlorfenprop), chlorflurenol, chlorflurenol-methyl, chloridazon, chlorimuron, chlorimuron-ethyl, chlorophthalim, chlorotoluron, chlorthal-dimethyl, chlorsulfuron, cinidon, cinidon-ethyl, cyclohexane (cinm) ethylin, cinosulfuron, clethodim, clodinafop, clodinafop-propargyl, cromazine, clonylid, cloransulam, cloransulam-methyl, cumyluron, cyanamide, cyanazine, cycloate, cyclosulfuron ron), cycloxydim, cyhalofop, cyhalofop-butyl, cyprazine, 2,4-D, 2,4-D-butoxyethyl ester, 2,4-D-butyl ester, 2,4-D-dimethylammonium, 2,4-D-diolamine (diolamin), 2,4-D-ethyl ester, 2,4-D-2-ethylhexyl ester, 2,4-D-isobutyl ester, 2,4-D-isooctyl ester, 2,4-D-isopropylammonium, 2,4-D-potassium, 2,4-D-triisopropanolammonium, 2,4-D-triolamine (trolamine), 2,4-DB, 2,4-DB-butyl ester, 2,4-DB-dimethylammonium,2,4-DB-isooctyl ester, 2,4-DB-potassium, 2,4-DB-sodium, daimuron (dymron), dalapon, dazomet, n-decanol, desmedipham, detosyl-pyrazolate (DTP), dicamba, dichlobenil, dichlorprop, dichlorprop-P, diclofop, diclofop-methyl, dic... lofop-P-methyl, diclosulam, difenzoquat, diflufenican, diflufenzopyr, diflufenzopyr-sodium, dimefuron, dimepiperate, dimethachlor, dimethametryn, dimethenamid, dimethenamid-P, dimetrasu lfuron, dinitramine, dinoterb, diphenamid, diquat, diquat-dibromid, dithiopyr, diuron, DNOC, endothal, EPTC, esprocarb, ethanalfluralin, ethametsulfuron, ethametsulfuron-methyl, ethiozidim n), ethofumesate, ethoxyfen, ethoxyfen-ethyl, ethoxysulfuron, etobenzanid, fenoxaprop, fenoxaprop-P, fenoxaprop-ethyl, fenoxaprop-P-ethyl, fenoxasulfone, fentrazamide, flampropHigh-efficiency dicofol flamprop-M-isopropyl, high-efficiency dicofol flamprop-M-methyl, flazasulfuron, floraulam, fluazifop, fluazifop-P, fluazifop-butyl, fluazifop-P-butyl, flucarbazone, flucarbazone-sodium, flucetosulfuron On, fluchloralin, flufenacet, flufenpyr, flufenpyr-ethyl, flumetsulam, flumiclorac, flumiclorac-pentyl, flumioxazin, fluometuron, fluoroglycofen, fluoroglycofen-ethyl, flupropanate, flupyrsulfuron pyrsulfuron, flupyrsulfuron-methyl-sodium, flurenol, flurenol-butyl, fluridone, flurochloridone, fluroxypyr, fluroxypyr-meptyl, flurtamone, fluthiacet, fluthiacet-methyl, fluthiamide, flusulfanilamide (fomesafen), flumethrin-sodium, foramsulfuron, fosamine, glufosinate, glufosinate-ammonium, glufosinate-P, glufosinate-P-ammonium, glufosinate-P-sodium, glyphosate, glyphosate-isopropylammoniumGlyphosate ammonium salt, glyphosate diammonium salt, glyphosate dimethyl ammonium salt, glyphosate potassium salt, glyphosate sodium salt, glyphosate trimethyl sulfide salt, halosulfuron, halosulfuron-methyl, haloxyfop, haloxyfop-P, haloxyfop-ethoxyethyl, haloxyfop-P-ethoxyethyl, haloxyfop-methyl, haloxyfop-P- methyl), hexazinone, imidacloprid, methyl imidacloprid, imidacloprid, imidacloprid ammonium, imidacloprid nicotinic acid, imidacloprid ammonium, imidacloprid nicotinic acid, imidacloprid ammonium, imidacloprid pyr, imidacloprid isopropylammonium, imidazoquinic acid, imidazoquinic acid ammonium. m), imazethapyr, imazethapyr-ammonium, imazosulfuron, indanofan, indaziflam, iodosulfuron, iodosulfuron-methyl-sodium, ioxynil, ioxynil-sodium, ioxynil-potassium, ioxynil-octanoate, ipfencarbaz One, isoproturon, isouron, isoxaben, isoxaflutole, karbutilate, ketospiradox, lactoferrin, lenacil, linuron, MCPA (salt, ester), MCPB (salt, ester), MCPB methyl ester, MCPB ethyl ester, MCPB sodium salt, 2-methyl-4-chloropropionic acid (mecoprop), sodium 2-methyl-4-chloropropionate, 2-methyl-4-chloropropionate butoxyethyl ester, homo-2-methyl-4-chloropropionic acid (mecoprop-P)Mecoprop-P-butotyl, mefenacet, mefluidide, mesosulfuron, mesosulfuron-methyl, mesotrione, metam, metamifop, metamitron, metazachlor, metazosulfuron, methabenzthiazuron, methiopyrisulfuron, methiozolin, methyl isothiocyanate, metobromuron, metolachlor, S-metolachlor, metosulam, metoxuron, metazanol Ribazin, Metsulfuron, Metsulfuron-methyl, Molinate, Monolinuron, Monosulfuron-ester, Napropamide, Neburon, Nicosulfuron, Nonanoic acid, Norflurazon, Oleic acid (fatty acid), Orbencarb, Orthosulfamuron, Oryzalin, Oxadiargyl, Oxadiazon, Oxasulfuron, Oxaziclomefon, Oxyfluorfen, Paraquat, Paraquat dichlorvos dichloride, pebulate, pendimethalin, penoxsulam, pentachlorphenol, pentoxazone, pethoxamid, petroleum oils, phenmedipham, phenmedipham-ethyl, picloram, picolinafen, pinoxadenPiperophos, pretilachlor, primisulfuron, primisulfuron-methyl, prodiamine, prifluraline, profoxydim, prometon, prometryn, propachlor, propanil, propaquizafop, propazine, propham, and isoprochlor opisochlor, propoxycarbazone, propoxycarbazone-sodium, propyrisulfuron, propyzamide, prosulfocarb, prosulfuron, pyraclonil, pyraflufen, pyraflufen-ethyl, pyrasulfotole, pyrazolynate, pyrazolate, pyrasulfuron zosulfuron, pyrazosulfuron-ethyl, pyrazoxyfen, pyribambenz, pyribambenz-isopropyl, pyribambenz-propyl, pyribenzoxim, pyributicarb, pyridafol, pyridate, pyriftalid, pyriminobac, pyriminobac-methyl, pyrimi Sulfan, pyrithiobac, pyrithiobac-sodium, pyroxasulfone, pyroxsulam, quinclorac, quinmerac, quinoclamine, quizalofop, quizalofop-ethyl, quizalofop-P, quizalofop-P-ethyl, quizalofop-P-tefurylRimsulfuron, saflufenacil, sethoxydim, siduron, simazine, simetryn, sulcotrione, sulfentrazone, sulfometuron, sulfometuron-methyl, sulfosate, and sulfosulfuron. Tebuthiuron, tefuryltrione, tembotrione, tepraloxydim, terbacil, terbucarb, terbumeton, terbuthylazin, terbutryn, thenylchlor, thiazopyr, thiencarbazone, thiencarbazone One or more of the following: carbazone-methyl, thifensulfuron, thifensulfuron-methyl, thiobencarb, toramezone, tralkoxydim, triafamone, triallate, triasulfuron, triaziflam, tribensulfuron-methyl, trifloxysulfuron, trifloxysulfuron-sodium, trifluralin, triflusulfuron, triflusulfuron-methyl, tritosulfuron, urea sulfate, and vernolate;

[0022] Furthermore, the plant growth regulators mentioned are selected from: abscisic acid, acibenzolar, acibenzolar-S-methyl, 5-aminolevulinic acid, cyclopropionidol, 6-benzylaminopurine, brassinolide, catechin, cloprop, cyclanilide, 3-(cycloprop-1-enyl)propionic acid, 3-(cycloprop-1-enyl)propionic acid, sodium salt, butyrylhydrazine, dazomet, n-decanol, dikegulac, and sodium dikegulac. Endothal, flumetralin, flurenol, flurenol-butyl, flurprimidol, forchlorfenuron, gibberellic acid, inabenfide, indole-3-acetic acid (IAA), 4-indole-3-ylbutyric acid, isoprothiolane, jasmonic acid, methyl jasmonic acid, kinetin, maleic hydrazide, mepiquat chloride Chloride), 1-methylcyclopropene, 2-(1-naphthyl)acetamide, 1-naphthylacetic acid, 2-naphthoxyacetic acid, nitrophenol mixture, 4-oxo-4-[(2-phenylethyl)amino]butyric acid, paclobutrazol, N-phenylphthalic acid, probenazol, prohexadione, calcium prohexadione, prohydrojasmone, propham, salicylic acid, strigolacton, tetrachloronitrobenzene, thidiazuron, triacontanol, trinexapac, tsitodef, uniconazole, uniconazole-P, or one or more of these.

[0023] Furthermore, the pesticide adjuvant is selected from one or more of the following: wetting agent, dispersant, emulsifier, thickener, disintegrant, antifreeze, defoamer, solvent, preservative, stabilizer, synergist or carrier;

[0024] Further, the wetting agent is selected from one or more of alkylbenzene sulfonates, alkylnaphthalene sulfonates, lignin sulfonates, sodium dodecyl sulfate, sodium dioctyl succinate sulfonate, α-olefin sulfonates, alkylphenol polyoxyethylene ethers, castor oil polyoxyethylene ethers, alkylphenol ethoxylates, fatty alcohol ethoxylates, sodium fatty alcohol polyoxyethylene ether sulfate, silkworm excrement, soapberry powder, soapberry powder, SOPA, detergents, emulsifiers 2000 series, and wetting and penetrating agents F; and / or

[0025] Further, the dispersant is selected from one or more of the following: lignin sulfonate, alkylnaphthalene sulfonate formaldehyde condensate, naphthalene sulfonate, tristyrylphenol ethoxylate phosphate, fatty alcohol ethoxylate, alkylphenol polyoxyethylene ether, alkylphenol polyoxyethylene ether methyl ether condensate sulfate, fatty amine polyoxyethylene ether, glycerol fatty acid ester polyoxyethylene ether, polycarboxylates, polyacrylic acids, phosphates, EO-PO block copolymers, and EO-PO graft copolymers; and / or

[0026] Further, the emulsifier is selected from one or more of the following: calcium dodecylbenzenesulfonate, alkylphenol formaldehyde resin polyoxyethylene ether, phenethylphenol polyoxyethylene polyoxypropylene ether, fatty alcohol ethylene oxide-propylene oxide copolymer, styrene-phenol polyoxyethylene ether, castor oil polyoxyethylene ether, and alkylphenol ether phosphate; and / or

[0027] Furthermore, the thickener is selected from one or more of xanthan gum, organobentonite, gum arabic, sodium alginate, magnesium aluminum silicate, carboxymethyl cellulose, and silica.

[0028] Furthermore, the disintegrant is selected from one or more of sodium sulfate, ammonium sulfate, aluminum chloride, sodium chloride, ammonium chloride, bentonite, glucose, sucrose, starch, cellulose, urea, sodium carbonate, sodium bicarbonate, citric acid, and tartaric acid.

[0029] Furthermore, the antifreeze is selected from one or more of alcohols, alcohol ethers, chlorinated hydrocarbons, and inorganic salts;

[0030] Furthermore, the defoamer is selected from C 10 -C 20 Saturated fatty acid compounds, silicone oil, silicone compounds, C8-C 10 One or more of the fatty alcohols; and / or

[0031] Furthermore, the solvent is selected from one or more of benzene, toluene, xylene, mesitylene, methanol, ethanol, isopropanol, n-butanol, dimethyl sulfoxide, dimethylformamide, cyclohexanone, hydrocarbon carbonate, diesel, solvent oil, vegetable oil, vegetable oil derivatives, and water;

[0032] Furthermore, the preservative is selected from one or more of propionic acid, sodium propionate, sorbic acid, sodium sorbate, potassium sorbate, benzoic acid, sodium benzoate, sodium p-hydroxybenzoate, methyl p-hydroxybenzoate, Kathon, and 1,2-benzisothiazolin-3-one;

[0033] Further, the stabilizer is selected from one or more of the following: disodium hydrogen phosphate, oxalic acid, succinic acid, adipic acid, borax, 2,6-di-tert-butyl-p-cresol, triethanolamine oleate, epoxidized vegetable oil, kaolin, bentonite, attapulgite, silica, talc, montmorillonite, and starch; and / or

[0034] Furthermore, the synergist is selected from synergistic phosphorus, synergistic ether, alkyl glycoside, etc.;

[0035] Furthermore, the carrier is selected from one or more of the following: ammonium salts, ground natural minerals, ground artificial minerals, silicates, resins, waxes, solid fertilizers, water, organic solvents, mineral oils, vegetable oils, and vegetable oil derivatives.

[0036] Furthermore; applying one or more pesticides selected from spraying, dusting, seed dressing, soil irrigation, granulation, fumigation, poison baiting, and injection.

[0037] The beneficial effects of this invention are as follows:

[0038] 1) High safety, safe for both current and subsequent crops;

[0039] 2) It has unique efficacy and significant effects, enabling precise application and reducing the occurrence of viral diseases in host plants;

[0040] 3) Environmentally friendly, low toxicity to humans and animals, and safe for users and environmental microorganisms. Detailed Implementation

[0041] To make the technical solution, objectives and advantages of the present invention clearer, the present invention is described with reference to the following specific embodiments. However, the present invention can be implemented in various forms and should not be limited to the embodiments described herein.

[0042] The technical solutions of the present invention will be clearly and completely described below with reference to the embodiments of the present invention. All other embodiments obtained by those skilled in the art based on the embodiments of the present invention without creative effort are within the scope of protection of the present invention.

[0043] Example 1:

[0044] Indoor toxicity testing

[0045] Test insect: palm thrips, which were raised indoors in an artificial climate chamber using kidney beans at a temperature of 25±1℃ and a humidity of 60±5%.

[0046] Insect stages: egg, 1st instar nymph, 2nd instar nymph, prepupa, pupa, adult;

[0047] Specific morphological classification:

[0048] Egg: Inside the tender tissues of a plant;

[0049] First instar nymph: white, without ocelli, without wing buds, only a pair of red compound eyes;

[0050] Second instar nymphs: pale yellow, relatively active, and crawl quickly;

[0051] Prepupa: Wing buds emerge, reaching the length of the 3rd and 4th abdominal segments, and the antennae extend forward;

[0052] Pupa: It grows 3 simple eyes, wing buds grow to 3 / 5 of the abdomen, and antennae extend backward along the body;

[0053] Adults: Emerge from the soil and move upwards.

[0054] Assay methods: Eggs were tested using the leaf immersion method, while other thrips instars were tested using the modified TIBS method (leaf tube film method) to determine the toxicity of the pesticides to each thrips in each instar. Five series concentrations of each test pesticide were prepared.

[0055] Table 1 Concentration gradients for each treatment

[0056]

[0057] Leaf dipping method - test procedure:

[0058] 1) Dip cabbage leaf discs (no fewer than 15) containing insect eggs into each concentration of the pesticide solution for 15 seconds, then transfer them to a petri dish. Repeat each pesticide concentration 4 times.

[0059] Investigation period: The investigation was conducted based on the hatching rate of the blank control, and the total number of eggs and the number of hatched eggs were recorded respectively, and the hatching rate was calculated.

[0060] TIBS method - test procedure:

[0061] 1) Fill each concentration of the drug solution into a 2mL centrifuge tube, let it stand for 4 hours, then discard the solution and let it air dry at room temperature for later use.

[0062] 2) Rinse the fresh, insect-free cabbage leaves clean, punch them into small leaf discs (1.5cm in diameter) with a hole punch, immerse the leaf discs in each concentration of the solution for 10 seconds, air dry them, and then transfer them to centrifuge tubes with different concentrations.

[0063] 3) Transfer approximately 20 healthy thrips of uniform development into each centrifuge tube, seal the tube with a 200-mesh screen, and repeat 4 times for each drug concentration.

[0064] Investigation period: 48 hours. Check the mortality of test insects, record the total number of insects and the number of dead insects, and calculate the mortality rate.

[0065] The toxicity regression equations for each compound were calculated using the DPS statistical analysis system, and the LC ratio was determined.50 Value (95% confidence interval) and LC 90 Value (95% confidence interval), correlation coefficient r 2 ;

[0066] Experimental results:

[0067] As shown in Table 2, compound (I) can inhibit the hatching of palm thrips eggs, but after treatment with 50, 100, 200, 400 and 800 ppm, its hatching rate reached 100%, indicating that compound (I) does not have ovicidal activity against palm thrips at low concentrations.

[0068] Table 2 shows the results of indoor toxicity tests of compound (I) on palm thrips eggs.

[0069]

[0070] Table 3 shows the results of compound (I) on the LC50 of palm thrips at different instars. 50 The values ​​showed significant differences. Among them, compound (I) had the highest insecticidal activity against 2nd instar nymphs, followed by adults, and poor insecticidal activity against 1st instar nymphs and pupae.

[0071] Table 3 shows the results of indoor toxicity tests of compound (I) against different instars of palm thrips.

[0072]

[0073] Example 2:

[0074] Test insect: Western flower thrips (frankliniella-occidentalis), which was raised indoors in an artificial climate chamber using cabbage at a temperature of 25±1℃ and a humidity of 60±5%.

[0075] Tested insect ages: 2nd instar nymphs and adults;

[0076] Determination method: Modified TIBS method (leaf tube film method), each test reagent was prepared into 5 series concentrations.

[0077] Table 4. Test reagents and treatment concentrations

[0078]

[0079]

[0080] Determination Method: TIBS Method - Test Procedure:

[0081] 1) Fill each concentration of drug solution into a 2mL centrifuge tube, let it stand for 4 hours, then discard the solution and let it air dry at room temperature for later use.

[0082] 2) Rinse the fresh, insect-free cabbage leaves clean, punch small leaf discs (1.5cm in diameter) with a hole punch, immerse the leaf discs in each concentration of the solution for 10 seconds, air dry, and then transfer them to centrifuge tubes with different concentrations.

[0083] 3) Transfer approximately 20 healthy thrips of uniform development into each centrifuge tube, seal the tube with a 200-mesh screen, and repeat 4 times for each drug concentration.

[0084] Investigation period: 48 hours. Check the mortality of test insects, record the total number of insects and the number of dead insects, and calculate the mortality rate.

[0085] The toxicity regression equations for each compound were calculated using the DPS statistical analysis system, and the LC ratio was determined. 50 Values ​​(95% confidence interval) and correlation coefficient r 2 .

[0086] Experimental results:

[0087] Table 5 shows the results of indoor toxicity tests of compound (I) against different instars of western flower thrips.

[0088]

[0089]

[0090] Example 3:

[0091] Tomato spotted wilt virus (TSWV);

[0092] Host plant: peanut, variety: Luhua 19;

[0093] Preparation of test materials: Peanut plants infected with tomato spotted wilt virus and healthy peanut plants (growth cycle: initial flowering stage);

[0094] Experimental method: Two hundred newly hatched second-instar nymphs of western flower thrips, all of uniform development, were raised indoors and transferred to infected peanut leaves for 30 minutes to feed on (the whole peanut plant was placed in a 200-mesh rearing cage). They were then transferred to rearing bottles (fresh kidney bean leaves) and reared for 2 days. The sublethal concentration (LC50) of each experimental pesticide was then used. 10 Forty thrips were treated with thrips immersion and then released onto healthy plants. The incidence rate of each treatment was investigated based on the disease incidence rate of the blank control.

[0095] Experimental treatment:

[0096] Table 6. Treatments and Experimental Concentrations

[0097]

[0098]

[0099] Experimental treatments: 20 peanut plants per treatment, with 4 replicates for each treatment;

[0100] Investigation method: 10 plants were investigated for each treatment, and the total number of plants investigated and the number of plants with diseases at each level were recorded on a plant-by-plant basis.

[0101] Grading method:

[0102] Level 0: Asymptomatic;

[0103] Grade 1: Some leaves develop yellow spots and necrosis;

[0104] Grade 3: Most leaves develop yellow spots and necrosis;

[0105] Level 5: Some leaf veins, stems and terminal buds are necrotic, wrinkled or the plant is slightly dwarfed;

[0106] Level 7: Most leaf veins, stems and terminal buds are necrotic, wrinkled or the plant is stunted;

[0107] Level 9: Dark brown stripes appear on the stem and petiole; the plant is severely stunted and may even die.

[0108] The disease index is calculated using the following formula:

[0109] Disease index = [∑(number of diseased plants at each level × relative level value) / (total number of plants surveyed × 9)] × 100

[0110] Results and Analysis:

[0111] The experimental results showed that treatment of thrips with compound (I) effectively controlled their ability to transmit viruses and reduced the incidence of disease in plants. Table 7 shows the results of the sublethal concentration (LC50) of compound (I) (treatment 1). 10 Treatment of western flower thrips can significantly reduce the disease index of tomato spotted wilt virus on peanuts.

[0112] Table 7. Disease incidence in peanuts under different treatments 10 days after application of pesticide.

[0113]

[0114]

[0115] Note: The survival rate (%) above is the average of each replication.

[0116] The above embodiments are merely exemplary implementations used to illustrate the principles of the invention. However, the invention is not limited thereto. Those skilled in the art can make various improvements and modifications without departing from the essence of the invention, and these improvements and modifications also fall within the protection scope of the invention.

Claims

1. The use of a substituted benzamide isoxazoline compound for the control of thalassoptera pests, characterized in that, The substituted benzamide isoxazoline compound is of formula (I): (I); The order Thysanoptera is the suborder Terebrantia Haliday, family Thripidae Stevens, and the pests of the family Thripidae are western flower thrips and palm thrips.

2. The use according to claim 1, characterized in that, The host plants of the aforementioned Thysanoptera pests are crops, including one or more of the following: grains, vegetables, fruits, nuts, sugar crops, oil crops, beverage crops, seasoning crops, forage crops, and medicinal plants.

3. A method for controlling thylacine pests, characterized in that, The compound of formula (I) of claim 1 or a combination thereof or a mixture thereof is applied at an effective dose to the Thysanoptera pests that need to be controlled or to the medium in which they grow, wherein the Thysanoptera is the suborder Terebrantia Haliday and the family Thripidae Stevens, and the Thripidae pests are western flower thrips and palm thrips.

4. The method according to claim 3, characterized in that, The composition containing formula (I) comprises a compound of formula (I) and an agriculturally permitted pesticide adjuvant.

5. The method according to claim 4, characterized in that, The pesticide adjuvant is selected from one or more of the following: wetting agent, dispersant, emulsifier, thickener, disintegrant, antifreeze, defoamer, solvent, preservative, stabilizer, synergist or carrier.

6. The method according to claim 3, characterized in that, The application method is selected from one or more pesticide application methods, including spraying, dusting, seed dressing, soil irrigation, granulation, fumigation, poison baiting, and injection.

Images