Ablation control methods, systems, devices, computer devices, storage media

Abstract

The application relates to an ablation control method, system, device, computer equipment, computer readable storage medium and computer program product. The method comprises: acquiring an ablation input power corresponding to a region to be ablated; providing an ablation signal to a target electrode to apply ablation energy to the region to be ablated, wherein the initial power of the ablation signal is less than the ablation input power; acquiring a physiological parameter during the application of the ablation energy to the region to be ablated. According to the physiological parameter, the ablation input power and the ablation progress, the target output power of the ablation energy corresponding to the ablation signal is determined, wherein the influence degree of the physiological parameter on the target output power is negatively correlated with the ablation progress, and the influence degree of the ablation input power on the target output power is positively correlated with the ablation progress. The power of the ablation signal is adjusted. By using the method, sympathetic nerves of the region to be ablated can be ablated without causing irreversible damage to nerve fibers during the ablation.

Description

Technical Field

[0001] This application relates to the field of medical technology, and in particular to an ablation control method, system, device, computer equipment, computer-readable storage medium, and computer program product. Background Technology

[0002] With the development of medical technology, minimally invasive ablation techniques have emerged. These techniques involve making small incisions in the skin, inserting electrode needles to the affected tissue, and then using high-voltage pulses generated between the electrodes to ablate the lesions, thus removing them. Overactive nerves can adversely affect human organs and tissues, leading to a series of cardiovascular diseases. For example, chronic overactivation of the sympathetic nervous system can cause excessive renin secretion, increased sodium reabsorption in the kidneys, increased cardiac output, and ultimately elevated blood pressure. If left uncontrolled, this vicious cycle can lead to high-risk cardiovascular events such as heart failure and stroke. Although various treatment methods exist for hypertension, less than 15% of patients in my country receive long-term, systematic treatment, and only 5% have their blood pressure controlled. Therefore, a long-term, effective treatment plan to help hypertensive patients control their blood pressure remains needed.

[0003] Currently, a method has been proposed to treat pulmonary hypertension by performing radiofrequency ablation of the pulmonary artery using a radiofrequency ablation catheter, namely renal sympathetic denervation (RDN). This procedure uses radiofrequency heating to block the autonomic nervous system surrounding the pulmonary artery, reducing sympathetic nerve tone and thus achieving a long-term therapeutic effect of lowering blood pressure. The principle is to ablate the sympathetic nerve fibers around the renal artery, reducing sympathetic nerve tone around the kidney, thereby increasing the glomerular filtration rate, reducing the kidney's reabsorption capacity, and decreasing the reabsorption of sodium ions and water, thus lowering blood pressure.

[0004] Known renal dendritic resection (RDN) procedures involve using a catheter to reach both renal arteries via the femoral artery. Electrodes on the catheter are controlled to release radiofrequency, ultrasound, or radiation energy in selected areas, causing localized high temperatures in the renal artery intima to block the conduction function of some sympathetic nerve fibers in the renal artery wall. RDN strategies based on renal artery anatomy have been proposed, using specialized catheter designs and increased treatment of distal branches of the renal artery to improve surgical outcomes. However, this method still has the following problems: (i) Clinical studies show that increasing the number of ablation sessions is insufficient to establish a clear relationship with the renal norepinephrine content, and the relationship between the selection of ablation segments and the antihypertensive effect remains unclear; (ii) Basic research has demonstrated that while the kidneys are innervated by sympathetic and sensory nerves, there are also nerve fibers that inhibit sympathetic nerve activity, such as parasympathetic nerves. Differential treatment targeting these nerve fibers cannot be achieved solely through segment selection.

[0005] Therefore, traditional ablation surgery techniques cannot provide differentiated treatment based on the state and distribution of nerve fibers, resulting in insufficient safety and a high risk of causing unnecessary damage to the patient. Summary of the Invention

[0006] Therefore, it is necessary to provide an ablation control method, system, device, computer equipment, computer-readable storage medium, or computer program product that is safer and can adaptively adjust the ablation power according to the physiological parameters of the object, in order to address the above-mentioned technical problems.

[0007] An ablation control method includes: acquiring an ablation input power corresponding to a region to be ablated; providing an ablation signal to a target electrode to control the target electrode to apply ablation energy to the region to be ablated, wherein the initial power of the ablation energy is less than the ablation input power; acquiring physiological parameters during the application of ablation energy to the region to be ablated, wherein the physiological parameters are physiological parameters of the target electrode's target object; determining a target output power of the ablation energy corresponding to the ablation signal based on the physiological parameters, the ablation input power, and the ablation progress, wherein the influence of the physiological parameters on the target output power decreases as the ablation progresses, and the influence of the ablation input power on the target output power increases as the ablation progresses.

[0008] In one embodiment, determining the target output power of the ablation energy corresponding to the ablation signal based on the physiological parameters, the ablation input power, and the ablation progress includes: acquiring the actual physiological parameters of the target electrode's target object and the corresponding target physiological parameters; determining the error amount of the physiological parameters during the ablation process based on the actual physiological parameters and the target physiological parameters; acquiring a first influence factor of the physiological parameters affecting the target output power and a second influence factor of the ablation input power affecting the target output power; wherein the magnitude of the first influence factor is negatively correlated with the ablation progress, and the magnitude of the second influence factor is positively correlated with the ablation progress; and determining the target output power of the ablation energy corresponding to the ablation signal based on the error amount, the first influence factor, the ablation input power, and the second influence factor.

[0009] In one embodiment, determining the target output power of the ablation energy corresponding to the ablation signal based on the error amount, the first influence factor, the ablation input power, and the second influence factor includes: determining a first power based on the product of the error amount and the first influence factor; determining a second power based on the product of the ablation input power and the second influence factor; and determining the target output power of the ablation energy corresponding to the ablation signal based on the sum of the first power and the second power.

[0010] In one embodiment, the ablation control method further includes: acquiring the changing trend of the physiological parameters during the ablation process; and determining whether to stop providing ablation signals to the target electrode based on the changing trend of the physiological parameters, the target output power, and the ablation duration corresponding to the current ablation progress.

[0011] In one embodiment, determining whether to stop providing ablation signals to the target electrode based on the changing trend of the physiological parameters, the target output power, and the ablation duration corresponding to the current ablation progress includes: determining the total ablation energy applied to the area to be ablated based on the target output power and the ablation duration; stopping the provision of ablation signals to the target electrode when the total ablation energy reaches a first threshold and the physiological parameters do not show an upward trend; and / or stopping the provision of ablation signals to the target electrode when the changing trend of the physiological parameters conforms to a preset changing trend and the total ablation energy reaches a second threshold.

[0012] In one embodiment, the ablation control method further includes: stopping the supply of ablation signals to the target electrode when the ablation time corresponding to the current ablation progress reaches a set time.

[0013] In one embodiment, adjusting the power of the ablation energy corresponding to the ablation signal according to the determined target output power includes: obtaining the actual power of the ablation signal output by the target electrode during the process of providing the ablation signal to the target electrode; and adjusting the power of the ablation energy corresponding to the ablation signal provided to the target electrode based on the difference between the actual power and the target output power, so that the actual power reaches the target output power.

[0014] In one embodiment, the ablation control method further includes: acquiring the actual temperature of the region to be ablated during the process of providing an ablation signal to the target electrode; and stopping the provision of the ablation signal to the target electrode when the actual temperature is greater than a third threshold.

[0015] In one embodiment, adjusting the power of the ablation energy corresponding to the ablation signal according to the determined target output power includes: acquiring the actual temperature of the region to be ablated during the process of providing the ablation signal to the target electrode; and adjusting the power of the ablation energy corresponding to the ablation signal provided to the target electrode based on the difference between the actual temperature and the target temperature, so that the actual temperature reaches the target temperature, wherein the target temperature corresponds to the target output power.

[0016] In one embodiment, the ablation control method further includes: during the process of adjusting the power of the ablation energy corresponding to the ablation signal provided to the target electrode based on the difference between the actual temperature and the target temperature, if the power of the ablation energy corresponding to the adjusted ablation signal is greater than the power limit when the target output power is greater than the power limit, then setting the power of the ablation energy corresponding to the ablation signal provided to the target electrode to the power limit.

[0017] An ablation control system, comprising:

[0018] An electrode assembly includes a conduit and at least one electrode spaced apart on the conduit;

[0019] An ablation module, connected to the at least one electrode, is used to provide an ablation signal to a target electrode, wherein the target electrode is one of the at least one electrodes;

[0020] The detection module is used to acquire the physiological parameters of the target electrode's target object;

[0021] A control module, connected to both the ablation module and the detection module, is used to acquire the ablation input power corresponding to the area to be ablated, control the ablation module to provide an ablation signal to the target electrode, and control the target electrode to apply ablation energy to the area to be ablated. During the process of providing the ablation signal to the target electrode, physiological parameters are acquired. Based on the physiological parameters, the ablation input power, and the ablation progress, the target output power of the ablation energy corresponding to the ablation signal is determined. Based on the determined target output power, the ablation module is controlled to adjust the power of the ablation energy corresponding to the ablation signal provided to the target electrode. The initial power of the ablation energy is less than the ablation input power. The influence of the physiological parameters on the target output power decreases as the ablation progresses, while the influence of the ablation input power on the target output power increases as the ablation progresses.

[0022] In one embodiment, the ablation control system further includes: a temperature sensor disposed on the catheter for collecting the temperature of the area to be ablated; a data acquisition module connected to the temperature sensor and the control module respectively for acquiring the temperature of the area to be ablated and transmitting it to the control module; the control module is further configured to control the ablation module to stop providing ablation signals to the target electrode when the temperature of the area to be ablated is greater than a set temperature.

[0023] An ablation control device, comprising:

[0024] The power acquisition module is used to acquire the ablation input power corresponding to the area to be ablated;

[0025] An output module is used to provide an ablation signal to the target electrode to control the target electrode to apply ablation energy to the area to be ablated, wherein the initial power of the ablation energy is less than the ablation input power;

[0026] The parameter acquisition module is used to acquire physiological parameters during the process of applying ablation energy to the area to be ablated, wherein the physiological parameters are the physiological parameters of the target electrode's target object;

[0027] A power determination module is used to determine the target output power of the ablation energy corresponding to the ablation signal based on the physiological parameters, the ablation input power, and the ablation progress. The influence of the physiological parameters on the target output power decreases as the ablation progresses, while the influence of the ablation input power on the target output power increases as the ablation progresses.

[0028] The adjustment module is used to adjust the power of the ablation energy corresponding to the ablation signal according to the determined target output power.

[0029] In one embodiment, a computer device is provided, including a memory and a processor, the memory storing a computer program, the processor executing the computer program to implement the aforementioned ablation control method.

[0030] In one embodiment, a computer-readable storage medium is provided having a computer program stored thereon, which, when executed by a processor, implements the aforementioned ablation control method.

[0031] In one embodiment, a computer program product is provided, the computer program product including a computer program that, when executed by a processor, implements the aforementioned ablation control method.

[0032] The aforementioned ablation control method, system, device, computer equipment, computer-readable storage medium, and computer program product. This method first obtains the ablation input power corresponding to the area to be ablated, i.e., obtains the reference rated power required for ablation of the area. This ablation input power can be directly input by the physician. Then, an ablation signal is provided to the target electrode, thereby applying ablation energy to the area to be ablated through the target electrode. This achieves ablation and removal of the area to be ablated. The initial power of the ablation signal is less than the ablation input power; that is, the power of the ablation energy corresponding to the initial ablation signal is very small, insufficient to achieve ablation and removal, but the damage to the area to be ablated is also very small. This is to facilitate subsequent gradual adjustment of the power of the ablation energy corresponding to the ablation signal based on physiological parameters, avoiding irreversible damage to the target due to excessively high initial ablation energy power. Then, during the application of ablation energy to the area to be ablated, physiological parameters are acquired. Then, based on physiological parameters, ablation input power, and ablation progress, the target output power of the ablation energy corresponding to the ablation signal is comprehensively determined. In determining the target output power, the influence of physiological parameters on the target output power is negatively correlated with the ablation progress, while the influence of the ablation input power on the target output power is positively correlated with the ablation progress. Therefore, in the initial stage of applying ablation energy to the area to be ablated, the target output power of the ablation energy corresponding to the ablation signal is mainly determined by physiological parameters. This allows the target output power of the ablation energy corresponding to the ablation signal to be adjusted according to physiological parameters, thus corresponding to the current state of the area to be ablated. In other words, the target output power is matched with the patient's real-time physiological parameters, ensuring that the power of the ablation energy corresponding to the ablation signal achieves the desired ablation and clearance effect while avoiding irreversible nerve damage due to excessive power. As the ablation progresses, the target output power converges towards the ablation input power input by the doctor, eventually converging to near the ablation input power to ensure the ablation effect. In summary, the method of this application can adaptively adjust the power of the ablation energy corresponding to the ablation signal according to the patient's physiological parameters during the ablation process, and ablate the sympathetic nerves in the area to be ablated while avoiding irreversible damage to nerve fibers during the ablation process. Attached Figure Description

[0033] To more clearly illustrate the technical solutions in the embodiments of this application or the conventional technology, the drawings used in the description of the embodiments or the conventional technology will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this application. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0034] Figure 1 Here is a flowchart of an ablation control method in one embodiment;

[0035] Figure 2 A flowchart of a method for determining the target output power of ablation energy corresponding to an ablation signal in one embodiment;

[0036] Figure 3 This is a schematic diagram of a blood pressure curve in one embodiment;

[0037] Figure 4 This is a flowchart illustrating a method for calculating the target output power in one embodiment;

[0038] Figure 5 This is a schematic diagram of the ablation power curve in one embodiment;

[0039] Figure 6 This is a schematic diagram of the ablation power curve in one embodiment;

[0040] Figure 7 This is a schematic diagram of the ablation power curve in one embodiment;

[0041] Figure 8 This is a flowchart illustrating a method for stopping ablation in one embodiment;

[0042] Figure 9 This is a flowchart illustrating a method for determining when to stop ablation in one embodiment;

[0043] Figure 10 This is a flowchart illustrating a method for adjusting power in one embodiment;

[0044] Figure 11 This is a flowchart illustrating the method for determining when to stop ablation in another embodiment;

[0045] Figure 12 This is a flowchart illustrating a method for adjusting power in another embodiment;

[0046] Figure 13 This is a flowchart illustrating the power regulation process in one embodiment;

[0047] Figure 14 This is a schematic diagram of the ablation control system in one embodiment;

[0048] Figure 15 This is a schematic diagram of the ablation control system in another embodiment;

[0049] Figure 16 This is a schematic diagram of the ablation control device in one embodiment;

[0050] Figure 17 This is an internal structural diagram of a computer device in one embodiment.

[0051] Explanation of reference numerals in the attached figures:

[0052] 11-Electrode, 12-Catheter, 20-Ablation module, 30-Detection module, 40-Control module, 50-Temperature sensor, 60-Acquisition module. Detailed Implementation

[0053] To facilitate understanding of this application, a more complete description will be provided below with reference to the accompanying drawings, which illustrate embodiments of the present application. However, the present application can be implemented in many different forms and is not limited to the embodiments described herein. Rather, these embodiments are provided so that the disclosure of this application will be thorough and complete.

[0054] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs. The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the application.

[0055] It is understood that the terms “first,” “second,” etc., used in this application may be used herein to describe various elements, but these elements are not limited by these terms. These terms are only used to distinguish one element from another.

[0056] It should be noted that when one element is considered to be "connected" to another element, it can be directly connected to the other element or connected to the other element through an intermediary element. Furthermore, in the following embodiments, "connection" should be understood as "electrical connection," "communication connection," etc., if there is transmission of electrical signals or data between the connected objects.

[0057] When used herein, the singular forms of “a,” “an,” and “the” may also include the plural forms unless the context clearly indicates otherwise. It should also be understood that the terms “comprising / including” or “having,” etc., specify the presence of the stated features, wholes, steps, operations, components, parts, or combinations thereof, but do not preclude the possibility of the presence or addition of one or more other features, wholes, steps, operations, components, parts, or combinations thereof. Meanwhile, the term “and / or” as used in this specification includes any and all combinations of the associated listed items.

[0058] In one embodiment, such as Figure 1 As shown, an ablation control method is provided, which includes steps S100-S140.

[0059] Step S100: Obtain the ablation input power corresponding to the area to be ablated.

[0060] Specifically, the ablation input power can be a power directly input by the doctor, that is, a power that can achieve a better ablation effect based on accumulated experience or surgical requirements.

[0061] Step S110: Provide an ablation signal to the target electrode to control the target electrode to apply ablation energy to the area to be ablated.

[0062] Specifically, the area to be ablated is a region located within the patient's body. Typically, a catheter with electrodes is inserted into the patient's body, allowing the electrodes to reach the area to be ablated. The target electrode is the electrode that releases ablation energy. An electrode is a device capable of outputting energy. When an ablation signal is provided to the electrode, it can release ablation energy in the vicinity of its location, achieving the ablation effect. By releasing ablation energy at the location of the target electrode, the nerves within the area to be ablated can be ablated.

[0063] In this application, the initial power of the ablation energy corresponding to the ablation signal is less than the ablation input power. The ablation signal can be high-power ablation energy, measured in watts. High-power ablation energy refers to energy that, when applied to a specific site, can cause destructive damage to cells in that site, leading to cell death. For example, the output power of the ablation energy can be 0-40W, adjustable as needed. In this application, the power of the ablation energy corresponding to the ablation signal gradually increases with the ablation progress. The initial ablation power can be 0-5W, which is very low and will not damage nerve fibers. This avoids using excessively high ablation power initially, as such high power is not necessary to ablate the sympathetic nerves in the area to be ablated, and excessive ablation power would damage nerve fibers. For example, to ablate the sympathetic nerves in the area to be ablated, only an ablation signal with an ablation power of 10W is needed. Using the method described in this application, the initial ablation power can be adjusted from 0-5W and gradually increased to 10W to ablate the sympathetic nerves. Simultaneously, the ablation power is not excessive, thus minimizing damage to nerve fibers. If a traditional method is used, such as directly employing an ablation signal with an ablation power of 30W, although the ablation effect can be achieved, it will cause irreversible damage to the nerve fibers.

[0064] Step S120: During the process of applying ablation energy to the area to be ablated, physiological parameters are obtained.

[0065] Among them, physiological parameters refer to the physiological parameters of the target electrode's target object.

[0066] Specifically, during the application of ablation energy to the area to be ablated, the physiological parameters of the target body will change. This is because the area to be ablated is stimulated by the ablation energy, and the stimulation received by the area can be reflected in the physiological parameters. Therefore, the physiological parameters of the target body can, to some extent, reflect the ablation effect and the ablation power. For example, the ablation energy generates heat, which increases the tension of nerves in the area to be ablated, activates endocrine changes, and thus affects blood pressure.

[0067] Step S130: Determine the target output power of the ablation energy corresponding to the ablation signal based on physiological parameters, ablation input power, and ablation progress.

[0068] Among them, the influence of physiological parameters on the target output power is negatively correlated with the ablation progress, while the influence of ablation input power on the target output power is positively correlated with the ablation progress. That is, the influence of physiological parameters on the target output power decreases as the ablation progresses, while the influence of ablation input power on the target output power increases as the ablation progresses.

[0069] Specifically, based on physiological parameters and ablation input power, combined with the ablation duration corresponding to the ablation progress, the target output power of the ablation energy corresponding to the ablation signal can be determined. In the initial stage of ablation, the target output power is primarily determined by physiological parameters. Therefore, in the initial stage of ablation, the ablation power corresponds to the physiological parameters. This allows the target output power of the ablation energy corresponding to the ablation signal to be adjusted according to the physiological parameters, ensuring that the power of the ablation energy corresponding to the ablation signal precisely achieves the ablation and removal effect, while avoiding irreversible nerve damage in the area to be ablated due to excessive power. As the ablation process progresses, to ensure the ablation effect, the target output power converges towards the ablation input power input by the doctor, eventually converging to near the ablation input power. This is because the ablation input power input by the doctor is usually correct. In this approach, the ablation power gradually increases with the ablation progress to near the ablation input power. Compared to directly using such a large ablation input power signal, this allows for a certain amount of reaction and buffer time. During the process of the ablation power converging to near the ablation input power, the ablation power can be adjusted in a timely manner based on the patient's real-time physiological parameters to ensure that the ablation signal does not cause irreversible damage to tissues that do not need ablation. This improves the safety and accuracy of ablation and reduces harm to the patient.

[0070] Step S140: Adjust the power of the ablation energy corresponding to the ablation signal according to the determined target output power.

[0071] Specifically, after determining the target output power, the power of the ablation energy corresponding to the current ablation signal will be adjusted to the target output power. The target output power is determined in real time based on physiological parameters, so the power of the ablation energy corresponding to the ablation signal will also be adjusted in real time as the ablation progresses.

[0072] In this embodiment, the ablation input power corresponding to the area to be ablated is first obtained, which is the reference rated power required for ablation of the area. This ablation input power can be directly input by the doctor. Then, an ablation signal is provided to the target electrode, thereby applying ablation energy to the area to be ablated through the target electrode. This achieves ablation and removal of the area to be ablated. The initial power of the ablation signal is less than the ablation input power; that is, the power of the ablation energy corresponding to the initial ablation signal is very small, insufficient to achieve ablation and removal, but the damage to the area to be ablated is also very small. This is to facilitate subsequent gradual adjustment of the power of the ablation energy corresponding to the ablation signal based on physiological parameters, avoiding irreversible damage to the target area due to excessively high initial ablation energy power. Then, physiological parameters are obtained during the application of ablation energy to the area to be ablated. Then, based on physiological parameters, ablation input power, and ablation progress, the target output power of the ablation energy corresponding to the ablation signal is comprehensively determined. In determining the target output power, the influence of physiological parameters on the target output power is negatively correlated with the ablation progress, while the influence of the ablation input power on the target output power is positively correlated with the ablation progress. Therefore, in the initial stage of applying ablation energy to the area to be ablated, the target output power of the ablation energy corresponding to the ablation signal is mainly determined by physiological parameters. This allows the target output power of the ablation energy corresponding to the ablation signal to be adjusted according to physiological parameters, thus corresponding to the current state of the area to be ablated. In other words, the target output power is matched with the patient's real-time physiological parameters, ensuring that the power of the ablation energy corresponding to the ablation signal achieves the desired ablation and clearance effect while avoiding irreversible nerve damage due to excessive power. As the ablation progresses, the target output power converges towards the ablation input power input by the doctor, eventually converging to near the ablation input power to ensure the ablation effect. In summary, the method of this application can adaptively adjust the power of the ablation energy corresponding to the ablation signal according to the patient's physiological parameters during the ablation process, and ablate the sympathetic nerves in the area to be ablated while avoiding irreversible damage to nerve fibers during the ablation process.

[0073] In one embodiment, such as Figure 2 As shown, step S130 determines the target output power of the ablation energy corresponding to the ablation signal based on physiological parameters, ablation input power, and ablation progress, including steps S200-S230.

[0074] Step S200: Obtain the actual physiological parameters of the target electrode's target object, as well as the corresponding target physiological parameters.

[0075] Step S210: Determine the error amount of physiological parameters during the ablation process based on the actual physiological parameters and the target physiological parameters.

[0076] Specifically, actual physiological parameters are the physiological parameters actually collected from the target electrode, which can be monitored in real time using monitoring or measuring instruments, such as blood pressure and heart rate. Target physiological parameters, on the other hand, are the ideal physiological parameters of the target object expected during the ablation process. In other words, if the physiological parameters of the target object change in accordance with the target physiological parameters during the ablation process, the ablation effect is considered better. Target physiological parameters are ideal physiological parameters summarized through big data and accumulated experience. Based on the deviation between the actual physiological parameters and the target physiological parameters, the error amount of the physiological parameters can be determined, which facilitates subsequent adjustment of the ablation energy power corresponding to the ablation signal, so that the physiological parameters are close to the target physiological parameters at the corresponding time.

[0077] For example, the trend of the target physiological parameter during the ablation process can be roughly summarized as follows: the physiological parameter slowly rises at the beginning of ablation, then maintains an upward trend for a period of time before turning downward. Taking blood pressure as an example, the patient's blood pressure is monitored in real time by an invasive blood pressure sensor. This invasive blood pressure sensor is a type of pressure sensor that converts pressure levels into electrical signals. The patient's blood pressure is read and fed back to a host computer to plot a blood pressure change curve with time (in seconds) on the x-axis and blood pressure (in mmHg) on ​​the y-axis. Specifically, the invasive blood pressure sensor converts the patient's real-time blood pressure into electrical signals at a certain frequency (e.g., 300Hz). A series of blood pressure data fed back continuously can then be plotted to obtain a curve... Figure 3 The raw blood pressure fluctuations shown are represented by a broken line with a continuous fluctuation at a certain frequency. Each fluctuation represents one of the patient's cardiac cycles, with peaks representing systolic pressure and troughs representing diastolic pressure. After reading the raw blood pressure fluctuations, the host computer automatically identifies the systolic and diastolic pressures within each cardiac cycle. This is done by marking the points where the slope changes from positive to negative as systolic pressure (peaks) and the points where the slope changes from negative to positive as diastolic pressure (troughs). With certain constraints, such as the minimum distance between two peaks and troughs, the minimum absolute value of a peak, and the maximum absolute value of a trough, the computer can automatically identify systolic and diastolic pressures.

[0078] The identified systolic blood pressure can be used to calculate the blood pressure baseline and blood pressure fluctuation line. Specifically, the blood pressure baseline is equal to the average systolic blood pressure in the 10 seconds before ablation. Using the time t = 0s at the start of ablation as the dividing line, the blood pressure to the left of the dividing line (t = -10s) represents the blood pressure in the 10 seconds before ablation, while the blood pressure to the right of the dividing line represents the blood pressure during the ablation process until its completion. Therefore, the blood pressure baseline is equal to the average of all systolic blood pressures to the left of the dividing line, while the blood pressure fluctuation line is calculated from all systolic blood pressures to the right of the dividing line, either by averaging or by using a fitting method.

[0079] Step S220: Obtain the first influencing factor of physiological parameters affecting the target output power, and the second influencing factor of ablation input power affecting the target output power.

[0080] Among them, the magnitude of the first influencing factor is negatively correlated with the ablation progress, thus the influence of physiological parameters on the target output power is negatively correlated with the ablation progress; the magnitude of the second influencing factor is positively correlated with the ablation progress, thus the influence of ablation input power on the target output power is positively correlated with the ablation progress.

[0081] Step S230: Determine the target output power of the ablation energy corresponding to the ablation signal based on the error amount, the first influence factor, the ablation input power, and the second influence factor.

[0082] Specifically, based on the error amount and the first influencing factor, the first power can be obtained, that is, the first power based on physiological parameters. Based on the ablation input power and the second influencing factor, the second power can be obtained, that is, the second power based on the ablation input power.

[0083] In this embodiment, based on the error between the actual physiological parameters and the target physiological parameters, and combined with the first influencing factor, the first power obtained based on the physiological parameters is determined. Based on the ablation input power and combined with the second influencing factor, the second power is determined. By combining the first power and the second power, the target output power of the ablation energy corresponding to the ablation signal can be obtained.

[0084] In one embodiment, such as Figure 4 As shown, step S230 determines the target output power of the ablation energy corresponding to the ablation signal based on the error amount, the first influence factor, the ablation input power, and the second influence factor, including steps S400-S420.

[0085] Step S400: Determine the first power based on the product of the error and the first influence factor.

[0086] For example, based on the deviation between the physiological parameters and the target physiological parameters, a PID (proportion-integral-differential) controller can be used to calculate the power value corresponding to the error. The PID controller can also set the proportional coefficient, integral coefficient, derivative coefficient, and corresponding adjustment amount according to the magnitude of the difference between the physiological parameters and the target physiological parameters, the rate of change, and the voltage limit requirements.

[0087] The power corresponding to the error is determined using the following formula:

[0088]

[0089] Where u(t) is the power corresponding to the error, e(t) is the deviation between the physiological parameter and the target physiological parameter, and K p K is the proportionality coefficient. i K is the integral coefficient. d is the differential coefficient.

[0090] The first power can be obtained by multiplying the power corresponding to the error by the first influence factor.

[0091] Step S410: Determine the second power based on the product of the ablation input power and the second influence factor.

[0092] Step S420: Determine the target output power of the ablation energy corresponding to the ablation signal based on the sum of the first power and the second power.

[0093] For example, the target output power is determined according to the following formula:

[0094]

[0095] Where u(t) is the power corresponding to the error, P input To ablate the input power, As the number one impact factor, is the second influencing factor, e is the natural index, t is the ablation time corresponding to the ablation progress, and a, b, and c are constants.

[0096] For example, during the ablation process, the change in target output power with the progress of ablation can be as follows: Figure 5As shown, in the initial stage of ablation, the ablation power starts from a low value and gradually increases. This is to accumulate heat to increase nerve tension in the ablation area, activating endocrine changes and thus altering physiological parameters. The ablation power increases with these physiological parameters, and both the rate and extent of this increase are related to these changes. If unexpected fluctuations in physiological parameters occur during this process, it indicates that there is no tissue in the current ablation area that needs ablation, or that there is tissue that should not be ablated, and ablation can be stopped promptly. If the changes in physiological parameters are as expected, then... Figure 5 As shown, the ablation power will continue to rise until it converges to near the ablation input power. The rate of increase in ablation power depends on the trend of physiological parameters. For example, if the physiological parameter is blood pressure, and blood pressure continues to rise, the corresponding power increase rate will adaptively maintain a relatively high level; conversely, it will maintain a relatively slow power increase rate. The final stable value of the ablation power is also related to physiological parameters. The final ablation power will adaptively maintain a level slightly higher or slightly lower than the ablation input power. Taking blood pressure as an example, if blood pressure continues to rise during ablation, it indicates that the target nerve fiber is located deep within the blood vessel wall, requiring effective ablation treatment. Therefore, the power output level needs to be adaptively increased based on the ablation input power. To maintain safety during ablation, the actual output power will not exceed the upper limit. If blood pressure has leveled off during ablation, it indicates that the current power output level is sufficient to reach the target nerve location. Continuing to increase the output power is meaningless and may cause damage to deeper, non-target tissues. Therefore, in this case, the power output level will level off before reaching the ablation input power.

[0097] For example, the target output power determined based on physiological parameters can also be discontinuous, meaning that the judgment is only made at the corresponding node based on physiological parameters over a period of time. For example... Figure 6 The diagram shows the analysis of physiological parameters during the 0-30s and 0-60s ablation processes, focusing only on the 30s and 60s intervals after the start of ablation, to determine the target output power. (See diagram for example.) Figure 7As shown, the target output power is determined by analyzing the blood pressure response during the 0-30s period of ablation, starting only 30s after the ablation begins. Because the analysis for determining the target output power is discontinuous, it can only begin at predetermined time points and cannot adaptively adjust the time of each point and the duration of each stage based on real-time blood pressure responses. Furthermore, power control within each stage can only be achieved through a predetermined function. However, the time of each point (which can be any time point within 0-100s, generally preferably 20, 30, 40 and 50, 60, 70) and the function used for power control within each stage (which can be a linear function, quadratic function, polynomial function, etc.) can be manually adjusted.

[0098] In this embodiment, the target output power of the ablation energy corresponding to the ablation signal is calculated based on the error amount, the first influence factor, the ablation input power, and the second influence factor, thus realizing the calculation of the target output power.

[0099] In one embodiment, such as Figure 8 As shown, the ablation control method also includes steps S800-S810.

[0100] Step S800: Obtain the trend of physiological parameters during the ablation process.

[0101] Specifically, physiological parameters are collected at preset intervals during the ablation process. The collected discrete physiological parameters are combined and plotted into a graph to obtain the trend of physiological parameter changes.

[0102] Step S810: Based on the changing trend of physiological parameters, target output power, and ablation duration corresponding to the current ablation progress, determine whether to stop providing ablation signals to the target electrode.

[0103] Specifically, the changing trend of physiological parameters can reflect the state of the area to be ablated after ablation energy is applied. Based on the target output power and the ablation duration corresponding to the current ablation progress, the total amount of ablation energy applied to the area to be ablated can be determined. Thus, based on the state of the area to be ablated and the total amount of ablation energy, it can be determined whether to stop providing ablation signals to the target electrode.

[0104] In this embodiment, based on the changing trend of physiological parameters, the target output power, and the ablation duration corresponding to the current ablation progress, it is determined whether to stop providing ablation signals to the target electrode, thereby enabling timely cessation of ablation energy output and preventing irreversible damage to the tissue in the area to be ablated.

[0105] In one embodiment, such as Figure 9As shown, in step S810, based on the changing trend of physiological parameters, the target output power, and the ablation time corresponding to the current ablation progress, it is determined whether to stop providing ablation signals to the target electrode, including steps S900-S920.

[0106] Step S900: Determine the total ablation energy applied to the area to be ablated based on the target output power and ablation duration.

[0107] Specifically, the total ablation energy applied to the area to be ablated can be obtained by multiplying the target output power by the corresponding ablation duration. For example, if an ablation power of 5W is applied for 5 seconds and then an ablation power of 10W is applied for 10 seconds, the total ablation energy is 5s*5W + 10s*10W. Alternatively, if the target output power is in the form of a function, the total ablation energy applied can be determined by integrating the function curve over time.

[0108] In step S910, when the total ablation energy reaches the first threshold and the physiological parameters do not show an upward trend, the ablation signal is stopped from being supplied to the target electrode.

[0109] Specifically, the first threshold is the energy level that can cause irreversible damage to the tissue within the ablation area. The absence of an upward trend in physiological parameters indicates that there are no nerves requiring ablation within the ablation area. If the total ablation energy reaches the first threshold, it means the ablation energy is sufficient and there are no nerves requiring ablation within the ablation area. However, because the ablation energy is insufficient to cause changes in physiological parameters, the physiological parameters still do not show an upward trend. Therefore, it is determined that there are no nerves requiring ablation within the ablation area, and ablation is stopped.

[0110] In step S920, if the trend of physiological parameter change conforms to the preset trend and the total ablation energy reaches the second threshold, the ablation signal is stopped from being provided to the target electrode.

[0111] Specifically, the second threshold is the energy level sufficient to ablate the nerves within the ablation area. When the total ablation energy reaches the second threshold, the nerves within the ablation area have definitely been ablated. If the trend of physiological parameters matches the preset trend, it indicates that the nerves within the ablation area are present and the ablation location is correct. Therefore, if the ablation location is correct and the ablation energy is sufficient, the nerves have been ablated, and ablation stops.

[0112] For example, when the physiological parameter is blood pressure, the ablation is considered complete when the blood pressure trend is first rising and then falling, and the total ablation energy reaches the second threshold. This is because the heat-activated nerve fibers have been completely blocked, and the blood pressure begins to drop.

[0113] In this embodiment, the decision to stop ablation is made based on the changing trends of total ablation energy and physiological parameters. This allows ablation to be stopped promptly when it is no longer necessary, ensuring that normal nerves are not damaged.

[0114] In one embodiment, the ablation control method further includes: stopping the supply of ablation signals to the target electrode when the ablation time corresponding to the current ablation progress reaches a set time.

[0115] Specifically, if the target nerve within the ablation area is located too deep, the ablation energy released by the electrodes may not reach its location. However, due to heat conduction, the target nerve may still be activated, causing physiological parameters such as blood pressure to remain high without any downward trend. In such cases, it is consistently determined that a target nerve exists within the ablation area, and ablation needs to continue. In this situation, even if the ablation time is increased, the ablation effect is very limited. Increasing the ablation power may cause superficial tissue to vaporize and explode. Therefore, in this case, ablation needs to be terminated, and other methods should be used, such as treating nearby tissues to block the deeply buried nerve fibers upstream and / or downstream of the nerve transmission pathway to remove the target nerve.

[0116] In this embodiment, if the ablation time is too long, the ablation needs to be terminated.

[0117] In one embodiment, such as Figure 10 As shown, step S140 adjusts the power of the ablation energy corresponding to the ablation signal according to the determined target output power, including steps S1000-S1010.

[0118] Step S1000: During the process of providing an ablation signal to the target electrode, the actual power of the ablation signal output by the target electrode is obtained.

[0119] Specifically, after determining the target output power, an ablation signal with the target output power is provided to the target electrode. During this process, the actual power of the ablation signal actually output by the target electrode is collected. Due to signal transmission errors or other factors, the actual power may not be consistent with the target output power.

[0120] Step S1010: Based on the difference between the actual power and the target output power, the power of the ablation energy corresponding to the ablation signal provided to the target electrode is adjusted to ensure that the actual power reaches the target output power.

[0121] Specifically, the difference between the actual power and the target output power is first determined. Then, based on this difference, a PI (proportion-integral) controller is used to calculate the correction power required to bring the actual power to the target output power through geometric and integral operations. The actual power is then adjusted according to this correction power. The geometric operation amplifies the difference, increasing the speed of power adjustment. However, a larger amplification results in faster adjustment but is also prone to over-adjustment or under-adjustment, causing the actual power to oscillate around the target output power. The integral operation accumulates the differences between the actual power and the target output power calculated each time, used to adjust errors in the same direction and for a longer duration. The correction power is obtained by combining the results of the geometric and integral operations. Using a PI controller allows for a relatively fast adjustment speed while minimizing the amplification of the difference to prevent oscillations.

[0122] For example, the correction power is determined by the following formula:

[0123] a(t) = K b b(t)+K a ∫0 t b(t)dt

[0124] Where a(t) is the corrected power, b(t) is the difference between the actual power and the target output power, and K b K is the proportionality coefficient. a is the integral coefficient.

[0125] In this embodiment, the power of the ablation energy corresponding to the ablation signal provided to the target electrode is adjusted based on the difference between the actual power and the target output power, thereby ensuring the accuracy of the power control of the ablation energy corresponding to the ablation signal.

[0126] In one embodiment, such as Figure 11 As shown, the ablation control method further includes steps S1100-S1110.

[0127] Step S1100: During the process of providing an ablation signal to the target electrode, the actual temperature of the area to be ablated is obtained.

[0128] Specifically, in addition to releasing ablation energy, the electrodes can also collect the temperature of the area to be ablated and convert the temperature into an electrical signal for transmission.

[0129] Step S1110: If the actual temperature is greater than the third threshold, stop providing ablation signals to the target electrode.

[0130] Specifically, the actual temperature of the area to be ablated is monitored. If the actual temperature is greater than the third threshold, it means that the actual temperature of the area to be ablated is too high, and continuing ablation will be dangerous. Therefore, the ablation signal is stopped from being provided to the target electrode.

[0131] In this embodiment, by monitoring the actual temperature of the area to be ablated, ablation can be stopped in a timely manner if the temperature is too high, thus ensuring the safety of ablation.

[0132] In one embodiment, such as Figure 12 As shown, step S140 adjusts the power of the ablation energy corresponding to the ablation signal according to the determined target output power, including steps S1200-S1210.

[0133] Step S1200: During the process of providing an ablation signal to the target electrode, the actual temperature of the area to be ablated is obtained.

[0134] Specifically, the actual temperature of the area to be ablated can be obtained through the target electrode.

[0135] Step S1210: Based on the difference between the actual temperature and the target temperature, the power of the ablation energy corresponding to the ablation signal provided to the target electrode is adjusted to ensure that the actual temperature reaches the target temperature.

[0136] The target temperature corresponds to the target output power.

[0137] Specifically, after determining the target output power, an ablation signal with the target output power is provided to the target electrode. The temperature corresponding to the target output power is taken as the target temperature. That is, after the ablation signal with the target output power is applied to the area to be ablated, its temperature should be the target temperature. However, due to signal transmission errors or other factors, the actual power of the ablation signal actually output by the target electrode may not be consistent with the target output power, resulting in a deviation between the actual temperature of the area to be ablated and the target temperature. Based on this deviation, a correction power is obtained after performing geometric and differential operations. The correction power is used to adjust the current actual power, so that the actual temperature of the area to be ablated reaches the target temperature. The geometric operation amplifies the difference, increasing the speed of power adjustment, while the differential operation calculates the rate of temperature change by comparing each measured actual temperature with the target temperature. If the temperature rises, the differential operation result is positive; if the temperature falls, the differential operation result is negative. By subtracting the result of the differential operation from the result of the geometric progression, and with a larger amplification factor to ensure a faster response, the rate of change of the differential operation can be used to control and prevent repeated temperature oscillations or rapid changes. Specifically, when the actual temperature rises too quickly, the result of the differential operation will be rapidly amplified to correct for the geometric progression under a high amplification factor, ensuring that the actual temperature does not exceed the target temperature and preventing the actual temperature from repeatedly oscillating around the target temperature.

[0138] For example, the correction power is determined by the following formula:

[0139]

[0140] Where c(t) is the determined correction power, h(t) is the deviation between the actual temperature and the target temperature, and K c K is the proportionality coefficient. d is the differential coefficient.

[0141] In this embodiment, the power of the ablation energy corresponding to the ablation signal provided to the target electrode is adjusted based on the difference between the actual temperature and the target temperature, thereby ensuring the accuracy of the power control of the ablation energy corresponding to the ablation signal.

[0142] In one embodiment, the ablation control method further includes: during the process of adjusting the power of the ablation energy corresponding to the ablation signal provided to the target electrode based on the difference between the actual temperature and the target temperature, if the power of the ablation energy corresponding to the adjusted ablation signal is greater than the power limit when the target output power is greater than the power limit, then setting the power of the ablation energy corresponding to the ablation signal provided to the target electrode as the power limit.

[0143] Specifically, during the ablation process, if the target output power is greater than the power limit, the power of the ablation energy corresponding to the adjusted ablation signal will be greater than the power limit during the adjustment of the actual power. To ensure safety, even if the actual temperature cannot reach the target temperature, the power of the ablation energy corresponding to the ablation signal provided to the target electrode can only be set to the power limit.

[0144] In this embodiment, by setting a power limit, the power of the ablation energy corresponding to the ablation signal is ensured to be not too high, thus ensuring the safety of ablation.

[0145] In one embodiment, such as Figure 13 As shown, a complete flowchart of an ablation process is provided, which includes steps S1300-S1430.

[0146] Step S1300: Obtain target blood pressure, actual blood pressure, and ablation input power.

[0147] In step S1310, the difference between the target blood pressure and the actual blood pressure is substituted into the PID controller to obtain the first power.

[0148] Step S1320: Based on the first power, ablate the input power to obtain the target output power.

[0149] Step S1330: Adjust the power of the ablation energy corresponding to the ablation signal according to the determined target output power.

[0150] In step S1340, if the power of the ablation energy corresponding to the adjusted ablation signal is greater than the power limit when the target output power is greater than the power limit, the power of the ablation energy corresponding to the ablation signal provided to the target electrode is set as the power limit.

[0151] Step S1350: Obtain the actual power of the ablation signal output by the target electrode.

[0152] Step S1360: Based on the difference between the actual power and the target output power, the power of the ablation energy corresponding to the ablation signal provided to the target electrode is adjusted according to feedback.

[0153] Step S1370: Obtain the actual temperature of the area to be ablated.

[0154] Step S1380: Based on the difference between the actual temperature and the target temperature, the power of the ablation energy corresponding to the ablation signal provided to the target electrode is adjusted according to feedback.

[0155] Step S1390: Determine whether the total ablation energy has reached the first threshold and whether the physiological parameters show an upward trend. If the total ablation energy reaches the first threshold and the physiological parameters show no upward trend, proceed to step S1430 to stop providing ablation signals to the target electrode; if the total ablation energy has not reached the first threshold or the physiological parameters show no upward trend, proceed to step S1400.

[0156] Step S1400: Determine whether the trend of physiological parameter changes conforms to the preset trend and whether the total ablation energy reaches the second threshold. If the trend of physiological parameter changes conforms to the preset trend and the total ablation energy reaches the second threshold, proceed to step S1430; if the trend of physiological parameter changes does not conform to the preset trend, or the total ablation energy reaches the second threshold, proceed to step S1410.

[0157] Step S1410: Determine whether the ablation time corresponding to the current ablation progress has reached the set time. If the ablation time corresponding to the current ablation progress has reached the set time, proceed to step S1430; otherwise, proceed to step S1420.

[0158] Step S1420: Determine whether the actual temperature is greater than the third threshold. If the actual temperature is greater than the third threshold, proceed to step S1430; if the actual temperature is less than or equal to the third threshold, return to step S1300.

[0159] Step S1430: Stop providing ablation signals to the target electrode.

[0160] In this embodiment, a complete process of ablation is provided, the contents of which have been described in the above embodiments and will not be repeated here.

[0161] It should be understood that, although Figure 1 , 2 The steps in flowcharts 4.8-13 are shown sequentially as indicated by the arrows; however, these steps are not necessarily executed in the exact order indicated by the arrows. Unless otherwise explicitly stated herein, there is no strict order in which these steps are performed; they can be executed in other orders. Furthermore, Figure 1 , 2 At least some of the steps in 4, 8-13 may include multiple steps or multiple stages. These steps or stages are not necessarily completed at the same time, but may be executed at different times. The execution order of these steps or stages is not necessarily sequential, but may be executed in turn or alternately with other steps or at least some of the steps or stages in other steps.

[0162] In one embodiment, such as Figure 14As shown, an ablation control system is provided, including: an electrode assembly, an ablation module 20, a detection module 30, and a control module 40, wherein:

[0163] The electrode assembly includes a conduit 12 and at least one electrode 11 spaced apart on the conduit 12.

[0164] Specifically, the catheter 12 carries the electrode 11 and enters the body of the target patient, thereby delivering the electrode 11 to the location where ablation is required. For example, the catheter 12 is inserted into the body via a unilateral femoral artery puncture, so that the electrode 11 can deliver radiofrequency ablation energy to the renal artery intima. The electrode 11 is a component capable of releasing energy, which can release ablation energy to achieve the ablation effect.

[0165] The ablation module 20 is connected to at least one electrode 11 and is used to provide an ablation signal to the target electrode 11, wherein the target electrode 11 is one of the at least one electrode 11.

[0166] Specifically, the ablation module 20 can output an ablation signal, which can be high-power ablation energy, measured in watts. High-power ablation energy refers to the energy that, when applied to a specific site, can cause destructive damage to cells in that site, leading to their death. For example, the output power of the ablation energy can be 0-40W, adjustable as needed.

[0167] The detection module 30 is used to acquire the physiological parameters of the target electrode 11.

[0168] Specifically, the detection module 30 can be an invasive blood pressure sensor or a heart rate monitor, etc. It can collect and acquire the physiological parameters of the target body in a conventional manner. The puncture sheath connecting the invasive blood pressure sensor and the catheter 12 enter the body from the left and right femoral arteries respectively, so as to avoid the blood pressure reading being affected by the movement of the catheter 12 during the operation.

[0169] The control module 40 is connected to both the ablation module 20 and the detection module 30. It acquires the ablation input power corresponding to the area to be ablated, controls the ablation module 20 to provide an ablation signal to the target electrode 11, and controls the target electrode 11 to apply ablation energy to the area to be ablated. During the process of providing the ablation signal to the target electrode 11, physiological parameters are acquired. Based on the physiological parameters, the ablation input power, and the ablation progress, the target output power of the ablation energy corresponding to the ablation signal is determined. Based on the determined target output power, the ablation module 20 adjusts the power of the ablation energy corresponding to the ablation signal provided to the target electrode 11.

[0170] Specifically, the initial power of the ablation signal is less than the ablation input power. The influence of physiological parameters on the target output power is negatively correlated with the ablation progress, while the influence of the ablation input power on the target output power is positively correlated with the ablation progress. In other words, the influence of physiological parameters on the target output power decreases as the ablation progresses, while the influence of the ablation input power on the target output power increases as the ablation progresses.

[0171] In this embodiment, by setting up an electrode assembly, ablation energy can be applied to the area to be ablated. By setting up an ablation module 20, an ablation signal can be provided to the electrode 11. By setting up a detection module 30, physiological parameters of the target area can be acquired. By setting up a control module 40, the ablation input power corresponding to the area to be ablated is first acquired, that is, the reference rated power for ablation of the area to be ablated is obtained. This ablation input power can be directly input by the doctor. Then, an ablation signal is provided to the target electrode 11, thereby applying ablation energy to the area to be ablated through the target electrode 11. This can achieve ablation and removal of the area to be ablated. The initial power of the ablation signal is less than the ablation input power, that is, the power of the ablation energy corresponding to the initial ablation signal is very small, which cannot achieve the ablation and removal effect, but the damage to the area to be ablated is also very small. This is to facilitate the gradual adjustment of the power of the ablation energy corresponding to the ablation signal according to the physiological parameters, and to avoid the initial ablation energy corresponding to the ablation signal being too large and causing irreversible damage to the target area. Then, during the process of applying ablation energy to the area to be ablated, physiological parameters are acquired. Then, based on physiological parameters, ablation input power, and ablation progress, the target output power of the ablation energy corresponding to the ablation signal is comprehensively determined. In determining the target output power, the influence of physiological parameters on the target output power is negatively correlated with the ablation progress, while the influence of the ablation input power on the target output power is positively correlated with the ablation progress. Therefore, in the initial stage of applying ablation energy to the area to be ablated, the target output power of the ablation energy corresponding to the ablation signal is mainly determined by physiological parameters. This allows the target output power of the ablation energy corresponding to the ablation signal to be adjusted according to physiological parameters, thus corresponding to the current state of the area to be ablated. In other words, the target output power is matched with the patient's real-time physiological parameters, ensuring that the power of the ablation energy corresponding to the ablation signal achieves the desired ablation and clearance effect while avoiding irreversible nerve damage due to excessive power. As the ablation progresses, the target output power converges towards the ablation input power input by the doctor, eventually converging to near the ablation input power to ensure the ablation effect. In summary, the method of this application can adaptively adjust the power of the ablation energy corresponding to the ablation signal according to the patient's physiological parameters during the ablation process, and ablate the sympathetic nerves in the area to be ablated while avoiding irreversible damage to nerve fibers during the ablation process.

[0172] In one embodiment, such as Figure 15 As shown, the ablation control system also includes: a temperature sensor 50 and a data acquisition module 60, wherein:

[0173] Temperature sensor 50 is installed on catheter 12 to collect the temperature of the area to be ablated.

[0174] The acquisition module 60 is connected to the temperature sensor 50 and the control module 40 respectively, and is used to acquire the temperature of the area to be ablated and transmit it to the control module 40.

[0175] The control module 40 is also used to control the ablation module 20 to stop providing ablation signals to the target electrode 11 when the temperature of the area to be ablated is greater than the set temperature.

[0176] In this embodiment, by setting a temperature sensor 50, the temperature of the area to be ablated is monitored. When the temperature of the area to be ablated is greater than the set temperature, the control module 40 can control the ablation module 20 to stop providing ablation signals to the target electrode 11, thereby ensuring the safety of the area to be ablated.

[0177] In one embodiment, such as Figure 16 As shown, an ablation control device is provided, comprising: a power acquisition module 1601, an output module 1602, a parameter acquisition module 1603, a power determination module 1604, and an adjustment module 1605, wherein:

[0178] The power acquisition module 1601 is used to acquire the ablation input power corresponding to the area to be ablated.

[0179] The output module 1602 is used to provide an ablation signal to the target electrode to control the target electrode to apply ablation energy to the area to be ablated, wherein the initial power of the ablation signal is less than the ablation input power.

[0180] The parameter acquisition module 1603 is used to acquire physiological parameters during the process of applying ablation energy to the area to be ablated, wherein the physiological parameters are the physiological parameters of the target electrode's target object.

[0181] The power determination module 1604 is used to determine the target output power of the ablation energy corresponding to the ablation signal based on physiological parameters, ablation input power and ablation progress. The influence of physiological parameters on the target output power decreases as the ablation progresses, while the influence of ablation input power on the target output power increases as the ablation progresses.

[0182] The adjustment module 1605 is used to adjust the power of the ablation energy corresponding to the ablation signal according to the determined target output power.

[0183] In one embodiment, the power determination module 1604 further includes: an error determination unit, a parameter determination unit, and a power determination unit, wherein:

[0184] The error determination unit is used to determine the amount of error in the physiological parameters during the ablation process based on the physiological parameters and the target physiological parameters.

[0185] The parameter determination unit is used to obtain the first influencing factor of physiological parameters affecting the target output power, and the second influencing factor of ablation input power affecting the target output power. The first influencing factor is negatively correlated with ablation progress, and the second influencing factor is positively correlated with ablation progress.

[0186] The power determination unit is used to determine the target output power of the ablation energy corresponding to the ablation signal based on the error amount, the first influence factor, the ablation input power, and the second influence factor.

[0187] In one embodiment, the power determination unit includes: a first calculation subunit, a second calculation subunit, and a third calculation subunit, wherein:

[0188] The first calculation subunit is used to determine the first power based on the product of the error and the first influence factor.

[0189] The second calculation subunit is used to determine the second power based on the product of the ablation input power and the second influence factor.

[0190] The third calculation subunit is used to determine the target output power of the ablation energy corresponding to the ablation signal based on the sum of the first power and the second power.

[0191] In one embodiment, the ablation control device further includes: a trend acquisition unit and a stop determination unit, wherein:

[0192] The trend acquisition unit is used to acquire the changing trends of physiological parameters during the ablation process.

[0193] The stop judgment unit is used to determine whether to stop providing ablation signals to the target electrode based on the changing trend of physiological parameters, target output power, and ablation duration corresponding to the current ablation progress.

[0194] In one embodiment, the stop determination unit includes: an energy determination subunit, a first stop subunit, and a second stop subunit, wherein:

[0195] The energy determination subunit is used to determine the total ablation energy applied to the region to be ablated based on the target output power and ablation duration.

[0196] The first stop subunit is used to stop providing ablation signals to the target electrode when the total ablation energy reaches a first threshold and the physiological parameters do not show an upward trend.

[0197] The second stop subunit is used to stop providing ablation signals to the target electrode when the trend of physiological parameter change conforms to the preset trend and the total ablation energy reaches the second threshold.

[0198] In one embodiment, the ablation control device further includes a stop module. The stop module is used to stop providing ablation signals to the target electrode when the ablation time corresponding to the current ablation progress reaches a set time.

[0199] In one embodiment, the adjustment module 1605 includes: a power acquisition unit and a first adjustment unit, wherein:

[0200] The power acquisition unit is used to acquire the actual power of the ablation signal output by the target electrode during the process of providing the ablation signal to the target electrode.

[0201] The first adjustment unit is used to adjust the power of the ablation energy corresponding to the ablation signal provided to the target electrode based on the difference between the actual power and the target output power, so that the actual power reaches the target output power.

[0202] In one embodiment, the adjustment module 1605 includes: a temperature acquisition unit and a second adjustment unit, wherein:

[0203] The temperature acquisition unit is used to acquire the actual temperature of the area to be ablated during the process of providing an ablation signal to the target electrode.

[0204] The second adjustment unit is used to adjust the power of the ablation energy corresponding to the ablation signal provided to the target electrode based on the difference between the actual temperature and the target temperature, so that the actual temperature reaches the target temperature, wherein the target temperature corresponds to the target output power.

[0205] In one embodiment, the ablation control device further includes: a temperature acquisition module and a stop output module, wherein:

[0206] The temperature acquisition module is used to acquire the actual temperature of the area to be ablated during the process of providing ablation signals to the target electrode.

[0207] The stop output module is used to stop providing ablation signals to the target electrode when the actual temperature exceeds the third threshold.

[0208] In one embodiment, the ablation control device further includes a limiting module. The limiting module is configured to, during the process of adjusting the power of the ablation energy corresponding to the ablation signal supplied to the target electrode based on the difference between the actual temperature and the target temperature, if the power of the adjusted ablation energy corresponding to the ablation signal is greater than the power limit when the target output power is greater than the power limit, set the power of the ablation energy corresponding to the ablation signal supplied to the target electrode as the power limit.

[0209] Specific limitations regarding the ablation control device can be found in the limitations of the ablation control method described above, and will not be repeated here. Each module in the aforementioned ablation control device can be implemented entirely or partially through software, hardware, or a combination thereof. These modules can be embedded in or independent of the processor in a computer device in hardware form, or stored in the memory of a computer device in software form, so that the processor can call and execute the operations corresponding to each module. It should be noted that the module division in this embodiment is illustrative and only represents a logical functional division; other division methods may be used in actual implementation.

[0210] In one embodiment, a computer device is provided, the internal structure of which can be shown in the following diagram. Figure 17 As shown, the computer device includes a processor, memory, and a network interface connected via a system bus. The processor provides computing and control capabilities. The memory includes non-volatile storage media and internal memory. The non-volatile storage media stores the operating system, computer programs, and a database. The internal memory provides an environment for the operation of the operating system and computer programs stored in the non-volatile storage media. The network interface is used to communicate with external terminals via a network connection. When the computer program is executed by the processor, it implements an ablation control method.

[0211] Those skilled in the art will understand that Figure 17 The structure shown is merely a block diagram of a portion of the structure related to the present application and does not constitute a limitation on the computer device to which the present application is applied. Specific computer devices may include more or fewer components than those shown in the figure, or combine certain components, or have different component arrangements.

[0212] In one embodiment, a computer device is provided, including a memory and a processor, wherein the memory stores a computer program, and the processor executes the computer program to implement the steps in the above-described method embodiments.

[0213] In one embodiment, a computer-readable storage medium is provided having a computer program stored thereon, which, when executed by a processor, implements the steps in the above method embodiments.

[0214] In one embodiment, a computer program product is provided, including a computer program that, when executed by a processor, implements the steps in the above method embodiments.

[0215] Those skilled in the art will understand that all or part of the processes in the methods of the above embodiments can be implemented by a computer program instructing related hardware. The computer program can be stored in a non-volatile computer-readable storage medium. When executed, the computer program can include the processes of the embodiments of the methods described above. Any references to memory, storage, databases, or other media used in the embodiments provided in this application can include at least one of non-volatile and volatile memory. Non-volatile memory can include read-only memory (ROM), magnetic tape, floppy disk, flash memory, or optical storage, etc. Volatile memory can include random access memory (RAM) or external cache memory. By way of illustration and not limitation, RAM can be in various forms, such as static random access memory (SRAM) or dynamic random access memory (DRAM), etc.

[0216] In the description of this specification, references to terms such as "some embodiments," "other embodiments," and "ideal embodiments" indicate that a specific feature, structure, material, or characteristic described in connection with that embodiment or example is included in at least one embodiment or example of the invention. In this specification, the illustrative descriptions of the above terms do not necessarily refer to the same embodiments or examples.

[0217] The technical features of the above embodiments can be combined in any way. For the sake of brevity, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0218] The embodiments described above are merely illustrative of several implementation methods of this application, and while the descriptions are relatively specific and detailed, they should not be construed as limiting the scope of the invention patent. It should be noted that those skilled in the art can make various modifications and improvements without departing from the concept of this application, and these all fall within the protection scope of this application. Therefore, the protection scope of this patent application should be determined by the appended claims.

Claims

1. An ablation control system, characterized in that, include: An electrode assembly includes a conduit and at least one electrode spaced apart on the conduit; An ablation module, connected to the at least one electrode, is used to provide an ablation signal to a target electrode, wherein the target electrode is one of the at least one electrodes; The detection module is used to acquire the physiological parameters of the target electrode's target object; A control module, connected to both the ablation module and the detection module, is used to acquire the ablation input power corresponding to the area to be ablated, control the ablation module to provide an ablation signal to the target electrode, and control the target electrode to apply ablation energy to the area to be ablated. During the process of providing the ablation signal to the target electrode, physiological parameters are acquired. Based on the physiological parameters, the ablation input power, and the ablation progress, the target output power of the ablation energy corresponding to the ablation signal is determined in real time. Based on the determined target output power, the ablation module is controlled to adjust the power of the ablation energy corresponding to the ablation signal provided to the target electrode. The initial power of the ablation energy is less than the ablation input power. The influence of the physiological parameters on the target output power decreases as the ablation progresses, while the influence of the ablation input power on the target output power increases as the ablation progresses.

2. The ablation control system according to claim 1, characterized in that, The ablation control system further includes: A temperature sensor, mounted on the catheter, is used to collect the temperature of the area to be ablated. The acquisition module is connected to the temperature sensor and the control module respectively, and is used to acquire the temperature of the area to be ablated and transmit it to the control module; The control module is also used to control the ablation module to stop providing ablation signals to the target electrode when the temperature of the area to be ablated is greater than the set temperature.

3. An ablation control device, characterized in that, include: The power acquisition module is used to acquire the ablation input power corresponding to the area to be ablated; An output module is used to provide an ablation signal to the target electrode to control the target electrode to apply ablation energy to the area to be ablated, wherein the initial power of the ablation energy is less than the ablation input power; The parameter acquisition module is used to acquire physiological parameters during the process of applying ablation energy to the area to be ablated, wherein the physiological parameters are the physiological parameters of the target electrode's target object; The power determination module is used to determine the target output power of the ablation energy corresponding to the ablation signal in real time based on the physiological parameters, the ablation input power, and the ablation progress. The influence of the physiological parameters on the target output power decreases as the ablation progresses, while the influence of the ablation input power on the target output power increases as the ablation progresses. The adjustment module is used to adjust the power of the ablation energy corresponding to the ablation signal according to the determined target output power.

4. The apparatus according to claim 3, characterized in that, The power determination module is further configured to acquire the actual physiological parameters of the target electrode's target object, and the corresponding target physiological parameters; and to determine the error amount of the physiological parameters during the ablation process based on the actual physiological parameters and the target physiological parameters. A first influencing factor affecting the target output power of the physiological parameters and a second influencing factor affecting the target output power of the ablation input power are obtained respectively; wherein, the magnitude of the first influencing factor is negatively correlated with the ablation progress, and the magnitude of the second influencing factor is positively correlated with the ablation progress; based on the error amount, the first influencing factor, the ablation input power, and the second influencing factor, the target output power of the ablation energy corresponding to the ablation signal is determined.

5. The apparatus according to claim 4, characterized in that, The power determination module includes: The first calculation subunit is used to determine the first power based on the product of the error amount and the first influence factor; The second calculation subunit is used to determine the second power based on the product of the ablation input power and the second influence factor; The third calculation subunit determines the target output power of the ablation energy corresponding to the ablation signal based on the sum of the first power and the second power.

6. The apparatus according to claim 3, characterized in that, The device further includes: The trend acquisition unit is used to acquire the changing trend of the physiological parameters during the ablation process; The stop determination unit is used to determine whether to stop providing ablation signals to the target electrode based on the changing trend of the physiological parameters, the target output power, and the ablation duration corresponding to the current ablation progress.

7. The apparatus according to claim 6, characterized in that, The stop determination unit includes: An energy determination subunit is used to determine the total ablation energy applied to the region to be ablated based on the target output power and the ablation duration. The first stop subunit is used to stop providing ablation signals to the target electrode when the total ablation energy reaches a first threshold and the physiological parameters do not show an upward trend. The second stop subunit is used to stop providing ablation signals to the target electrode when the trend of change of the physiological parameters conforms to a preset trend and the total ablation energy reaches a second threshold.

8. The apparatus according to claim 4, characterized in that, The device further includes: The stop module is used to stop providing ablation signals to the target electrode when the ablation time corresponding to the current ablation progress reaches the set time.

9. The ablation control device according to claim 4, characterized in that, The adjustment module includes: The power acquisition unit is used to acquire the actual power of the ablation energy corresponding to the ablation signal output by the target electrode during the process of providing an ablation signal to the target electrode. The first adjustment unit is used to adjust the power of the ablation energy corresponding to the ablation signal provided to the target electrode based on the difference between the actual power and the target output power, so that the actual power reaches the target output power.

10. The apparatus according to claim 4, characterized in that, The device further includes: The temperature acquisition module is used to acquire the actual temperature of the area to be ablated during the process of providing an ablation signal to the target electrode; The stop output module is used to stop providing ablation signals to the target electrode when the actual temperature is greater than the third threshold.

11. The apparatus according to claim 4, characterized in that, The adjustment module includes: A temperature acquisition unit is used to acquire the actual temperature of the area to be ablated during the process of providing an ablation signal to the target electrode. The second adjustment unit is used to adjust the power of the ablation energy corresponding to the ablation signal provided to the target electrode based on the difference between the actual temperature and the target temperature, so that the actual temperature reaches the target temperature, wherein the target temperature corresponds to the target output power.

12. The apparatus according to claim 11, characterized in that, The device further includes: The limiting module is used to adjust the power of the ablation energy corresponding to the ablation signal provided to the target electrode based on the difference between the actual temperature and the target temperature. If the power of the ablation energy corresponding to the adjusted ablation signal is greater than the power limit when the target output power is greater than the power limit, the module sets the power of the ablation energy corresponding to the ablation signal provided to the target electrode to the power limit.

13. A computer device comprising a memory and a processor, wherein the memory stores a computer program, characterized in that, When the processor executes the computer program, it performs the following steps: Obtain the ablation input power corresponding to the region to be ablated; An ablation signal is provided to the target electrode to control the target electrode to apply ablation energy to the region to be ablated, wherein the initial power of the ablation energy is less than the ablation input power; During the process of applying ablation energy to the area to be ablated, physiological parameters are acquired, wherein the physiological parameters are the physiological parameters of the target electrode's target object; Based on the physiological parameters, the ablation input power, and the ablation progress, the target output power of the ablation energy corresponding to the ablation signal is determined in real time. The influence of the physiological parameters on the target output power decreases as the ablation progresses, while the influence of the ablation input power on the target output power increases as the ablation progresses. The power of the ablation energy corresponding to the ablation signal is adjusted according to the determined target output power.

14. The computer device according to claim 13, characterized in that, When the processor executes the computer program, it also performs the following steps: Obtain the actual physiological parameters of the target electrode's target object, as well as the corresponding target physiological parameters; Based on the actual physiological parameters and the target physiological parameters, determine the error amount of the physiological parameters during the ablation process; A first influencing factor on the physiological parameters affecting the target output power and a second influencing factor on the ablation input power affecting the target output power are obtained respectively; wherein, the magnitude of the first influencing factor is negatively correlated with the ablation progress, and the magnitude of the second influencing factor is positively correlated with the ablation progress; The target output power of the ablation energy corresponding to the ablation signal is determined based on the error amount, the first influence factor, the ablation input power, and the second influence factor.

15. The computer device according to claim 14, characterized in that, When the processor executes the computer program, it also performs the following steps: The first power is determined by multiplying the error amount by the first influence factor; The second power is determined by multiplying the ablation input power by the second influence factor; The target output power of the ablation energy corresponding to the ablation signal is determined based on the sum of the first power and the second power.

16. The computer device according to claim 13, characterized in that, When the processor executes the computer program, it also performs the following steps: Obtain the trend of the physiological parameters during the ablation process; Based on the changing trend of the physiological parameters, the target output power, and the ablation duration corresponding to the current ablation progress, it is determined whether to stop providing ablation signals to the target electrode.

17. The computer device according to claim 16, characterized in that, When the processor executes the computer program, it also performs the following steps: The total ablation energy applied to the region to be ablated is determined based on the target output power and the ablation duration. When the total ablation energy reaches the first threshold and the physiological parameters do not show an upward trend, the ablation signal is stopped from being supplied to the target electrode. And / or, if the trend of change of the physiological parameters conforms to a preset trend and the total ablation energy reaches a second threshold, the ablation signal is stopped from being provided to the target electrode.

18. The computer device according to claim 13, characterized in that, When the processor executes the computer program, it also performs the following steps: When the ablation time corresponding to the current ablation progress reaches the set time, the supply of ablation signals to the target electrode is stopped.

19. The computer device according to claim 13, characterized in that, When the processor executes the computer program, it also performs the following steps: During the process of providing an ablation signal to the target electrode, the actual power of the ablation energy corresponding to the ablation signal output by the target electrode is obtained; Based on the difference between the actual power and the target output power, the power of the ablation energy corresponding to the ablation signal provided to the target electrode is adjusted to ensure that the actual power reaches the target output power.

20. The computer device according to claim 13, characterized in that, When the processor executes the computer program, it also performs the following steps: During the process of providing an ablation signal to the target electrode, the actual temperature of the area to be ablated is obtained; If the actual temperature exceeds the third threshold, the ablation signal is stopped from being supplied to the target electrode.

21. The computer device according to claim 13, characterized in that, When the processor executes the computer program, it also performs the following steps: During the process of providing an ablation signal to the target electrode, the actual temperature of the area to be ablated is obtained; Based on the difference between the actual temperature and the target temperature, the power of the ablation energy corresponding to the ablation signal provided to the target electrode is adjusted to make the actual temperature reach the target temperature, wherein the target temperature corresponds to the target output power.

22. The computer device according to claim 21, characterized in that, When the processor executes the computer program, it also performs the following steps: During the process of adjusting the power of the ablation energy corresponding to the ablation signal provided to the target electrode based on the difference between the actual temperature and the target temperature, if the power of the ablation energy corresponding to the adjusted ablation signal is greater than the power limit when the target output power is greater than the power limit, then the power of the ablation energy corresponding to the ablation signal provided to the target electrode is set to the power limit.

23. A computer-readable storage medium having a computer program stored thereon, characterized in that, When the computer program is executed by the processor, it performs the following steps: Obtain the ablation input power corresponding to the region to be ablated; An ablation signal is provided to the target electrode to control the target electrode to apply ablation energy to the region to be ablated, wherein the initial power of the ablation energy is less than the ablation input power; During the process of applying ablation energy to the area to be ablated, physiological parameters are acquired, wherein the physiological parameters are the physiological parameters of the target electrode's target object; Based on the physiological parameters, the ablation input power, and the ablation progress, the target output power of the ablation energy corresponding to the ablation signal is determined in real time. The influence of the physiological parameters on the target output power decreases as the ablation progresses, while the influence of the ablation input power on the target output power increases as the ablation progresses. The power of the ablation energy corresponding to the ablation signal is adjusted according to the determined target output power.

24. The computer-readable storage medium according to claim 23, characterized in that, When the computer program is executed by the processor, it also performs the following steps: Obtain the actual physiological parameters of the target electrode's target object, as well as the corresponding target physiological parameters; Based on the actual physiological parameters and the target physiological parameters, determine the error amount of the physiological parameters during the ablation process; A first influencing factor on the physiological parameters affecting the target output power and a second influencing factor on the ablation input power affecting the target output power are obtained respectively; wherein, the magnitude of the first influencing factor is negatively correlated with the ablation progress, and the magnitude of the second influencing factor is positively correlated with the ablation progress; The target output power of the ablation energy corresponding to the ablation signal is determined based on the error amount, the first influence factor, the ablation input power, and the second influence factor.

25. The computer-readable storage medium according to claim 24, characterized in that, When the computer program is executed by the processor, it also performs the following steps: The first power is determined by multiplying the error amount by the first influence factor; The second power is determined by multiplying the ablation input power by the second influence factor; The target output power of the ablation energy corresponding to the ablation signal is determined based on the sum of the first power and the second power.

26. The computer-readable storage medium according to claim 23, characterized in that, When the computer program is executed by the processor, it also performs the following steps: Obtain the trend of the physiological parameters during the ablation process; Based on the changing trend of the physiological parameters, the target output power, and the ablation duration corresponding to the current ablation progress, it is determined whether to stop providing ablation signals to the target electrode.

27. The computer-readable storage medium according to claim 26, characterized in that, When the computer program is executed by the processor, it also performs the following steps: The total ablation energy applied to the region to be ablated is determined based on the target output power and the ablation duration. When the total ablation energy reaches the first threshold and the physiological parameters do not show an upward trend, the ablation signal is stopped from being supplied to the target electrode. And / or, if the trend of change of the physiological parameters conforms to a preset trend and the total ablation energy reaches a second threshold, the ablation signal is stopped from being provided to the target electrode.

28. The computer-readable storage medium according to claim 23, characterized in that, When the computer program is executed by the processor, it also performs the following steps: When the ablation time corresponding to the current ablation progress reaches the set time, the supply of ablation signals to the target electrode is stopped.

29. The computer-readable storage medium according to claim 23, characterized in that, When the computer program is executed by the processor, it also performs the following steps: During the process of providing an ablation signal to the target electrode, the actual power of the ablation energy corresponding to the ablation signal output by the target electrode is obtained; Based on the difference between the actual power and the target output power, the power of the ablation energy corresponding to the ablation signal provided to the target electrode is adjusted to ensure that the actual power reaches the target output power.

30. The computer-readable storage medium according to claim 23, characterized in that, When the computer program is executed by the processor, it also performs the following steps: During the process of providing an ablation signal to the target electrode, the actual temperature of the area to be ablated is obtained; If the actual temperature exceeds the third threshold, the ablation signal is stopped from being supplied to the target electrode.

31. The computer-readable storage medium according to claim 23, characterized in that, When the computer program is executed by the processor, it also performs the following steps: During the process of providing an ablation signal to the target electrode, the actual temperature of the area to be ablated is obtained; Based on the difference between the actual temperature and the target temperature, the power of the ablation energy corresponding to the ablation signal provided to the target electrode is adjusted to make the actual temperature reach the target temperature, wherein the target temperature corresponds to the target output power.

32. The computer-readable storage medium according to claim 31, characterized in that, When the computer program is executed by the processor, it also performs the following steps: During the process of adjusting the power of the ablation energy corresponding to the ablation signal provided to the target electrode based on the difference between the actual temperature and the target temperature, if the power of the ablation energy corresponding to the adjusted ablation signal is greater than the power limit when the target output power is greater than the power limit, then the power of the ablation energy corresponding to the ablation signal provided to the target electrode is set to the power limit.

33. A computer program product, comprising a computer program, characterized in that, When the computer program is executed by the processor, it performs the following steps: Obtain the ablation input power corresponding to the region to be ablated; An ablation signal is provided to the target electrode to control the target electrode to apply ablation energy to the region to be ablated, wherein the initial power of the ablation energy is less than the ablation input power; During the process of applying ablation energy to the area to be ablated, physiological parameters are acquired, wherein the physiological parameters are the physiological parameters of the target electrode's target object; Based on the physiological parameters, the ablation input power, and the ablation progress, the target output power of the ablation energy corresponding to the ablation signal is determined in real time. The influence of the physiological parameters on the target output power decreases as the ablation progresses, while the influence of the ablation input power on the target output power increases as the ablation progresses. The power of the ablation energy corresponding to the ablation signal is adjusted according to the determined target output power.

34. The computer program product according to claim 33, characterized in that, When a computer program is executed by a processor, it also performs the following steps: Obtain the actual physiological parameters of the target electrode's target object, as well as the corresponding target physiological parameters; Based on the actual physiological parameters and the target physiological parameters, determine the error amount of the physiological parameters during the ablation process; A first influencing factor on the physiological parameters affecting the target output power and a second influencing factor on the ablation input power affecting the target output power are obtained respectively; wherein, the magnitude of the first influencing factor is negatively correlated with the ablation progress, and the magnitude of the second influencing factor is positively correlated with the ablation progress; The target output power of the ablation energy corresponding to the ablation signal is determined based on the error amount, the first influence factor, the ablation input power, and the second influence factor.

35. The computer program product according to claim 34, characterized in that, When a computer program is executed by a processor, it also performs the following steps: The first power is determined by multiplying the error amount by the first influence factor; The second power is determined by multiplying the ablation input power by the second influence factor; The target output power of the ablation energy corresponding to the ablation signal is determined based on the sum of the first power and the second power.

36. The computer program product according to claim 33, characterized in that, When a computer program is executed by a processor, it also performs the following steps: Obtain the trend of the physiological parameters during the ablation process; Based on the changing trend of the physiological parameters, the target output power, and the ablation duration corresponding to the current ablation progress, it is determined whether to stop providing ablation signals to the target electrode.

37. The computer program product according to claim 36, characterized in that, When a computer program is executed by a processor, it also performs the following steps: The total ablation energy applied to the region to be ablated is determined based on the target output power and the ablation duration. When the total ablation energy reaches the first threshold and the physiological parameters do not show an upward trend, the ablation signal is stopped from being supplied to the target electrode. And / or, if the trend of change of the physiological parameters conforms to a preset trend and the total ablation energy reaches a second threshold, the ablation signal is stopped from being provided to the target electrode.

38. The computer program product according to claim 33, characterized in that, When a computer program is executed by a processor, it also performs the following steps: When the ablation time corresponding to the current ablation progress reaches the set time, the supply of ablation signals to the target electrode is stopped.

39. The computer program product according to claim 33, characterized in that, When a computer program is executed by a processor, it also performs the following steps: During the process of providing an ablation signal to the target electrode, the actual power of the ablation energy corresponding to the ablation signal output by the target electrode is obtained; Based on the difference between the actual power and the target output power, the power of the ablation energy corresponding to the ablation signal provided to the target electrode is adjusted to ensure that the actual power reaches the target output power.

40. The computer program product according to claim 33, characterized in that, When a computer program is executed by a processor, it also performs the following steps: During the process of providing an ablation signal to the target electrode, the actual temperature of the area to be ablated is obtained; If the actual temperature exceeds the third threshold, the ablation signal is stopped from being supplied to the target electrode.

41. The computer program product according to claim 33, characterized in that, When a computer program is executed by a processor, it also performs the following steps: During the process of providing an ablation signal to the target electrode, the actual temperature of the area to be ablated is obtained; Based on the difference between the actual temperature and the target temperature, the power of the ablation energy corresponding to the ablation signal provided to the target electrode is adjusted to make the actual temperature reach the target temperature, wherein the target temperature corresponds to the target output power.

42. The computer program product according to claim 41, characterized in that, When a computer program is executed by a processor, it also performs the following steps: During the process of adjusting the power of the ablation energy corresponding to the ablation signal provided to the target electrode based on the difference between the actual temperature and the target temperature, if the power of the ablation energy corresponding to the adjusted ablation signal is greater than the power limit when the target output power is greater than the power limit, then the power of the ablation energy corresponding to the ablation signal provided to the target electrode is set to the power limit.

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