Traditional Chinese medicine composition for treating atopic dermatitis and preparation method thereof

Abstract

The invention discloses a traditional Chinese medicine composition for treating atopic dermatitis and a preparation method thereof, and relates to the technical field of atopic dermatitis treatment.The traditional Chinese medicine composition is prepared from honey-fried licorice roots, raw rhizoma atractylodis macrocephalae, cassia twigs, radix paeoniae alba, moutan bark, radix polygonati officinalis, red dates and fresh ginger. The traditional Chinese medicine is prepared from the following raw materials by mass: 14-18 g of honey-fried licorice root, 12-16 g of raw bighead atractylodes rhizome, 8-12 g of cassia twig, 12-17 g of radix paeoniae alba, 4-8 g of moutan bark, 4-6 g of radix polygonati officinalis, 25-35 g of red dates and 13-17 g of fresh ginger. The traditional Chinese medicine composition for treating atopic dermatitis has the advantages of definite curative effect, convenience in administration and small toxic and side effects, has the effects of tonifying middle-jiao qi, ridging up and thinning wood, soothing and dispersing evil, astringing and lowering lung gold and nourishing body fluid, is used for treating atopic dermatitis, has definite curative effect, and can achieve the effects of relieving itching, removing rash and moistening skin, so that the living quality of patients is improved, the disease burden is relieved, and the curative effect is obvious. And the preparation method is simple and convenient, easy to manufacture and low in cost.

Description

Technical Field

[0001] The invention relates to the technical field of atopic dermatitis treatment, and in particular to a traditional Chinese medicine composition for treating atopic dermatitis and a preparation method thereof. Background Art

[0002] Atopic dermatitis is a chronic, recurrent, pruritic, inflammatory disease with a high prevalence, and the disease burden ranks first among non-fatal dermatological diseases. The disease is highly heterogeneous and has diverse clinical phenotypes, which poses a challenge to treatment. Traditional treatments are difficult to meet clinical needs. In recent years, biological agents and molecular targeted drugs have significantly improved the treatment level of moderate to severe AD patients, but there is still a lack of sufficient data to evaluate the balance between its benefits and safety, and there are still many problems that need to be solved.

[0003] As an important means of treating AD, TCM internal treatment has accumulated a lot of clinical experience. According to the consensus of relevant experts and literature reports, the basic treatment principles in clinical practice are clearing heat, strengthening the spleen, removing dampness, nourishing blood and removing wind. Through the data platform, the commonly used drugs for the treatment of atopic dermatitis in the national patented Chinese medicine compound are Phellodendron, Sophora flavescens, Kochia scoparia, Dictamni, etc., mainly with clearing heat, removing dampness, removing wind and relieving itching as the basic treatment principles and medication rules. The so-called "differentiation and treatment" and "addition and subtraction according to symptoms" are essentially summaries of clinical experience. The medication is complicated, the principles are not understood, and it is inevitable that it is arbitrary and there is no relative standard, resulting in unstable efficacy. Summary of the invention

[0004] In view of the deficiencies in the prior art, the present invention provides a Chinese medicine composition for treating atopic dermatitis and a preparation method thereof, which solves the problems raised in the above-mentioned background technology.

[0005] To achieve the above objectives, the present invention is implemented through the following technical scheme: a Chinese medicine composition for treating atopic dermatitis and a preparation method thereof, comprising the following specific constituent raw materials:

[0006] Roasted licorice root, raw atractylodes, cinnamon twig, white peony root, peony bark, polygonatum, red dates, ginger;

[0007] The specific proportions according to the quality of raw materials are as follows:

[0008] Roasted licorice root 14-18g, raw white atractylodes 12-16g, cinnamon twig 8-12g, white peony root 12-17g, peony bark 4-8g, polygonatum 4-6g, red dates 25-35g, ginger 13-17g.

[0009] Optionally, the ratio of various raw materials in the traditional Chinese medicine composition is as follows:

[0010] 15g of roasted licorice root, 15g of raw white atractylodes, 10g of cinnamon twig, 15g of white peony root, 5g of peony bark, 5g of polygonatum, 30g of red dates, and 15g of ginger.

[0011] Optionally, the ratio of various raw materials in the traditional Chinese medicine composition is as follows:

[0012] Roasted licorice root 16g, raw white atractylodes 16g, cinnamon twig 11g, white peony root 15g, peony bark 6g, polygonatum odoratum 4g, red dates 28g, and ginger 14g.

[0013] A method for preparing a Chinese medicine composition for treating atopic dermatitis as claimed in any one of the above claims, comprising the following specific steps:

[0014] Step 1: Use a dryer to dry all the above raw materials and reduce the humidity of the raw materials to 20-30%;

[0015] Step 2: Use a grinder to process the raw materials into powder, pass through a 150-200 mesh sieve for 30-45 minutes, and set the downward pressure of the grinder to 3-4.5N / cm 2 ;

[0016] Step 3: Grind the unscreened raw materials for a second time until they pass through a 100-mesh sieve;

[0017] Step 4: Add distilled water and mix them evenly with a stirrer. The mass ratio of the raw material to the distilled water is 1-1.3:2, and the stirring speed is 30-45r / min;

[0018] Step 5: After stirring evenly, heat it to 55-70°C and continue stirring for 20-30 minutes;

[0019] Step 6: Heat the mixer evenly to 80-95°C and cook for 30-50 minutes;

[0020] Step 7: Add vegetable oil to the mixture and continue stirring until it becomes viscous;

[0021] Step 8: Continue heating to reduce the water content to 35-48%;

[0022] Step 9: Get the Chinese medicine paste.

[0023] Optionally, the vegetable oil in step seven is tea oil, and the mass ratio of the vegetable oil to the mixed material is 1-1.5:4.

[0024] The present invention provides a Chinese medicine composition for treating atopic dermatitis and a preparation method thereof, which has the following beneficial effects:

[0025] Roasted Licorice: Sweet in taste, mild in nature, slow in nature; enters the Taiyin spleen and Yangming stomach meridians; enters the boundary of metal and wood, returns to the water and fire, cultivates the central region, and nourishes the four sides; when a person is born, the ancestral qi is first formed, the two yin and yang are not distinguished, the four images are not yet manifested, and it is chaotic and inexplicable, which is called the innate; the ancestral qi moves, turns left and turns into Ji earth, turns right and turns into Wu earth, and the spleen and stomach are born; Ji earth rises in the east and turns into Yi wood, rises in the south and turns into Ding fire; Wu earth descends in the west and turns into Xin metal, descends in the north and turns into Gui water, so the four images are complete and The five elements are complete; wood is warm, fire is hot, water is cold, and metal is cool, which are the qi of the four images; wood is sour, metal is pungent, fire is bitter, and water is salty, which are the tastes of the four images; earth is in the middle of the four qi, the correct color of the four colors, and the neutral taste of the four; the qi, color, smell, and taste of licorice are neutral and peaceful, and it has the virtue of earth, so it goes to the center palace and enters the spleen and stomach; the spleen earth warms up and transforms into liver wood, the liver is responsible for storing blood and the spleen is the source of blood production, the stomach earth clears and descends and transforms into lung metal, the lung is responsible for storing qi and the stomach is the source of qi transformation, qi and blood are divided into palaces, and they all have earth qi; licorice has the five virtues, supplemented by blood If it is a medicine, it will go to the left and enter the liver to warm up and transform into liver wood. The liver is responsible for storing blood and the spleen is the source of blood production. The stomach earth is clear and descending and transforms into lung metal. The lung is responsible for storing qi and the stomach is the source of qi transformation. Qi and blood are divided into palaces and all have earth qi. Licorice has five virtues. When it is supplemented with blood medicine, it will go to the left and enter the liver wood. When it is supplemented with qi medicine, it will go to the right and enter the lung metal. The liver blood warms up and transforms into spirit qi. The lung metal is clear and descending and transforms into essence and blood. The spleen and stomach are the emperor of spirit qi and blood. The spleen and stomach are indispensable for regulating qi and blood and copulating spirit. Licorice is indispensable; diseases of the liver and spleen are prone to sinking, so those that enter the liver and spleen should be supplemented with flavors that can ascend and reach; diseases of the lungs and stomach are prone to upward reversal, so those that enter the lungs and stomach should be supplemented with descending and astringent products; vomiting is upward reversal of the lungs and stomach, and the stagnant qi cannot be released upward, so it will feel stuffy in the heart and chest; diarrhea is the sinking of the liver and spleen, and the stagnant qi cannot be released downward, so it will feel bloated in the abdomen and flanks, all due to the deficiency of the middle qi; for upward reversal, nourish the middle and replenish the earth, so as to relieve depression and ascend the sunken, so vomiting and bloating are not inappropriate for licorice;

[0026] Atractylodes macrocephala: sweet, slightly bitter, enters the Stomach Meridians of Foot Yangming and Spleen Meridians of Foot Taiyin; nourishes the middle and dries dampness, quenches thirst and produces body fluids, is most beneficial to the spleen essence, greatly nourishes the stomach qi, descends turbid yin and promotes food intake, is good at stopping vomiting, ascends clear yang and eliminates water and grain, and can cure diarrhea; the spleen is Taiyin and embraces yang qi, so it warms and rises to transform wood and fire, the stomach is Yangming and contains yin essence, so it descends and produces metal and water; when the stomach descends, it is empty and tolerant, so food can be swallowed without vomiting, when the spleen ascends, it grinds and rots, so grain is digested without benefit; the nature of the five elements is that fire is dry and water is wet, Taiyin spleen earth rises from water content, and because of the water content it transforms dampness, Yangming stomach earth descends to the fire position, and because of the fire position it transforms dryness; Taiyin's dampness is beneficial The dryness of Yangming relieves the dampness of Taiyin, and the dryness and dampness are in harmony, and the Qi in the middle rotates, so the stomach absorbs the spleen and eliminates vomiting and diarrhea. However, the Taiyin spleen and earth are commanded by damp earth, and the Yangming stomach follows the dry metal to transform Qi. Xin metal and Ji earth both belong to Taiyin, but Xin metal is not as damp as Ji earth, and Geng metal and Wu earth both belong to Yangming, but Wu earth is not as dry as Geng metal. It is due to the transformation of people that they cannot resist the prosperity of those who command themselves. It is also the decline of people. Fire is depleted and water is abundant, dryness is eliminated and dampness is increased. Dampness causes the Qi in the middle to stagnate, the pivot cannot move, and the rise and fall are reversed, causing the spleen to sink and the stomach to reverse. When the spleen sinks, Yi wood cannot reach, and it suppresses Ji earth below, so that water and food cannot be digested and become diarrhea. When the stomach reverses, Jia wood loses its home and suppresses Wu above. Earth, food cannot be taken in and causes vomiting; Atractylodes macrocephala replenishes earth and dries out dampness, and when the earth is dry, it rises and falls as before, so it can treat vomiting and diarrhea at the same time; all products that remove dampness are often damaged by dryness; Atractylodes macrocephala has a strong smell and rich juice, which can nourish the stomach qi and replenish the spleen qi, and is the best for producing body fluids and relieving dryness and thirst; dampness and excessive dampness are good for damaging body fluids; as earth is dry and metal is clear, the lung qi descends and turns into rain and dew; the misty and floating dew qi is moist and lubricated, which is called body fluids; body fluids penetrate and irrigate the internal organs, so there is no thirst; dampness causes qi stagnation and body fluids coagulation, excessive production of phlegm, and loss of nourishment to the internal organs, which often causes dryness and thirst; there is not much body fluid, and it is lost through sweating, the dampness is exacerbated and the dryness is damaged; adding Atractylodes macrocephala removes dampness and nourishes body fluids, This is the golden rope for removing dampness and inducing sweating. The power of the interaction between water and fire lies in the earth. Water turns into wood and fire due to the left rotation of Ji earth, and fire turns into metal and water due to the right rotation of Wu earth. Earth is the middle qi of water and fire. When the middle qi is strong, Wu earth is dormant and sealed, and the yin descends and embraces the yang. Under the nine earths, it is always warm and spring-like. Ji earth rises and develops, and the yang rises and contains the yin. Above the nine heavens, it is always cold and autumn-like. When the middle qi is weak, Wu earth rises inversely and loses its dormant function. Fire flies and the disease is hot in the upper part. Ji earth sinks and goes against its policy of development. Water sinks and the disease is cold in the lower part. Therefore, diseases caused by fire, water and cold must be caused by the failure of the earth. Zhongjing used Baizhu in the prescriptions of Wuling, Zhenwu, Fuzi and Zexie to treat water.

[0027] Cinnamon twig: sweet, spicy, fragrant, warm in nature; enters the liver meridian of foot jueyin and bladder meridian of foot taiyang; enters the liver to circulate blood, runs through the meridians to reach the ying stagnation, is good at relieving wind evil, is the best at regulating wood qi, raising the clear yang to escape the depression, lowering the turbid yin to rush against the flow, relieving the acute contraction of tendons and veins, relieving the obstruction of joints, enters the liver and gallbladder to disperse the depression, extremely relieves pain, dredges the meridians to relieve numbness and astringency, and even removes dampness and cold, can stop the running pig, and calm the palpitations;

[0028] Guizhi is pungent, warm and dispersing, and enters the liver and spleen to circulate blood. Wind injures the defensive qi, which blocks the blood. Guizhi can reach the meridians, relieve the stagnation of the blood and release the hair, so it is good at expelling wind evil. The liver corresponds to spring and is responsible for life, but only one in ten people has sufficient vitality. Even if they do, they are strong and healthy without getting sick. Those who get sick are all those with insufficient vitality. Wood is born in water and grows on earth. When the water is warm and the earth is dry, the yang qi rises and then the vitality is flourishing. When the water is cold and the earth is wet, the vitality is out of order and stagnates and suppresses the earth. Because its life is not going well, it becomes depressed and acts as a thief. When the liver is sick, dryness, astringency and blood stasis will occur, and the meridians will also be sick. Wood contains fire, and its qi is originally warm. If the warm qi is preserved, it will be blocked and cause wind-heat. If the warm qi is insufficient, the wind-heat will not occur and it will be purely dampness and cold. The dampness and cold are the decline of vitality, and the wind-heat is not the prosperity of vitality. This is the general case of liver disease.

[0029] Guizhi warms and disperses, and its nature is compatible with the liver. It makes the internal organs' qi smooth and the menstrual blood flow smoothly, so it is good at relieving spleen depression; the meridians are prosperous and the qi is spread, the earth qi is loose and harmonious, and both earth and wood are in harmony; when the earth is regulated in the middle, the axis rotates and the wood qi is prosperous and harmonious, so it can both reduce adverse effects and raise the sunken, calm palpitations, and stop the running pig; as for regulating menstruation and opening and closing, relieving pain, clearing the meridians and removing numbness, activating the meridians and relaxing the muscles, it can also treat choking, bloating, pain, turbidity, stranguria, diarrhea, acid regurgitation, bloody stools, miscarriage, rectal prolapse, metrorrhagia and leukorrhea, all of which are its best. Generally speaking, there are hundreds of miscellaneous symptoms, which are not caused by adverse effects of the lungs and stomach, but by the sunken liver and spleen. Guizhi is suitable for both adverse effects and sunken effects, and it is suitable for all of them. It is difficult to list all the good works and the special effects are difficult to describe in detail; all medicines that moisten the liver and nourish the blood, once they have Guizhi, can transform the stagnant Yin into the Yang, nourish the vitality, and promote prosperity, which is beyond the reach of other medicines.

[0030] Peony: sour, slightly bitter, slightly cold, enters the liver meridian of foot Jueyin and the gallbladder meridian of foot Shaoyang; enters the liver to clear the wind, goes to the gallbladder to purge heat; is good at regulating the heart's restlessness and palpitations, relieves abdominal pain and fullness, disperses the heat in the chest and ribs, and stretches the cramps in the legs and feet; vomiting and bleeding are completely cured, metrorrhagia and metrorrhagia are all stopped, diarrhea and leukorrhea are all effective, and hemorrhoids and scrofula are also effective; Yang is rooted in water, rises to the liver and spleen, and transforms into Ding fire, water is cold and soil is wet, spleen Yang is depressed, and the way for liver wood to rise is blocked, then it is depressed and overcomes spleen earth, and abdominal pain and urgency are caused; Jueyin is the wind and wood qi, business is not successful, and the accumulated depression is angry, which produces wind and dryness, so Jueyin diseases must have wind evil; wind is of the nature of dispersion, and it is suppressed by wind and wood, and the order of dispersion is carried out, such as leukorrhea, leukorrhea, metrorrhagia, metrorrhagia, leukorrhea, and nocturnal emission, Initially, it is due to depression and the desire to heal and relieve, but in the end, it is still depression because of the desire to relieve. Whether it is blocked or unblocked, it is all due to wind and dryness. Peony is sour and cold and enters the liver. It is specialized in clearing wind and dryness and restraining and relieving. Therefore, it is good at treating Jueyin wood depression and wind movement. The liver and gallbladder have the same qi inside and outside. It can clear wind and wood from below and clear the fire from above, and it has a quick effect. However, it can relieve the wind and fire of the liver and gallbladder, and also weaken the yang of the spleen and stomach. "Treatise on Febrile Diseases" says: "When Taiyin is sick, the pulse is weak, and the patient has continuous diarrhea, if rhubarb and peony are to be used, it should be reduced, because the patient's stomach qi is weak and easily moved." For all wind and wood diseases, and the spleen and stomach are weak, it is appropriate to reduce the dosage slightly, and use it together with ginger, cinnamon, Poria, and Atractylodes, and treat both earth and wood. If it causes loose stools, it cannot be used. Huangqin Decoction and Da Chaihu are used to treat Shaoyang diarrhea, with Jia wood overcoming Wu earth, so it can relieve Shaoyang fire from below.

[0031] Polygonatum odoratum: sweet in taste, enters the Taiyin Lung Meridian; clears the lung metal and moistens dryness, nourishes the liver wood and clears the wind;

[0032] It is used to treat Jueyin disease, sore throat, vomiting pus and blood, because metal is punished by fire, and Weirui clears metal and moistens dryness; Weirui is peaceful and moisturizing, transforms qi and produces body fluid, quenches thirst and relieves restlessness, clears metal and promotes water, replenishes qi and moistens dryness; its main treatments include relieving thirst, relieving stranguria, moisturizing the skin, removing black spots, treating red and swollen canthus, and treating blurred vision;

[0033] Peony bark: bitter, pungent, slightly cold, enters the foot Jueyin liver meridian; it can relieve wood stagnation and clear wind, promote blood stasis and purge heat, expel pus and blood from carbuncle, and resolve visceral masses; Peony bark is pungent, cool, and has a purging effect, is good at resolving blood clots and breaking up old masses, relieving stagnant heat and clearing wind and dryness; because blood is in the liver, liver wood is suppressed, blood vessels cannot flow, resulting in stasis and wind-heat; blood stasis is dispersed, wood is released and wind is cleared, and liver heat subsides; its main treatments include dredging meridians, promoting the flow of fetuses, clearing blood heat, cooling bone steaming, stopping vomiting and bleeding, stopping stranguria, healing injuries, healing fractures, eliminating leprosy, and eliminating paralysis;

[0034] Ginger: spicy, warm in nature, enters the Stomach Meridian of Foot Yangming, Spleen Meridian of Foot Taiyin, Liver Meridian of Foot Jueyin, Lung Meridian of Hand Taiyin; it can relieve nausea and vomiting, relieve fullness and depression, enter the lungs and stomach to drive away turbidity, move to the liver and spleen to relieve stagnation, remove chest congestion, expel stomach congestion, relieve nasal congestion, stop abdominal pain, harmonize the internal organs, promote the circulation of Ying and Wei, is an essential product for menstruation, and a good medicine for releasing qi; the body's qi, the clear yang rises to the liver and spleen on the left, and the turbid yin descends to the lungs and stomach on the right; stomach earth Chonghe, Qihua right turn, then Xin metal clear down, breath back to the root; Ren water flow, drop by drop back to the source, mist and dew scattered, body fluids flow, down to the streams and valleys, rivers and canals into the drainage, so that the lower part is not empty and the upper part is not full; if the lungs and stomach do not descend, then Qi and water are reversed, the bladder below is blocked, urination cannot be carried out, the chest and diaphragm above are blocked, body fluids are not distributed, so phlegm and water, wheezing, cough, nausea and vomiting diseases arise; ginger clears and clears, descends to the lungs and stomach and It can lower turbid Yin, stop vomiting and remove stasis and rot, and has the most rapid power to clear the palace and remove the channels. Because the lungs and stomach are responsible for contraction, if the contraction is not strong, it will go against the flow and cause blockage. Ginger can open up the blockage and restore the normal contraction, so it can turn the reverse into a smooth flow. It is originally a lung-draining product, and it can drain the lungs without damaging the deficiency. Its good nature is especially valuable. Qi is strong in the lungs and stomach, but its essence is based on the liver and spleen. The warm Qi in the blood is the root of the lung Qi. Yang Qi is first born in Yi wood has not grown vigorously yet, so the liver and spleen qi are prone to depression. Ginger is pungent and dispersing, which is good at relieving liver and spleen depression. Jujube has a mellow temperament and is the best for nourishing the liver and spleen. However, if it is blocked and cannot flow, ginger can be used to regulate it, so that the essence can flow and replenish without stagnation. It is used in jujube, cinnamon and peony, which can both harmonize the middle and release the qi. If the meridians are blocked, stagnant and slow, it is appropriate to add ginger to the products that nourish the Ying and Wei to spread it, so that it can flow without obstruction.

[0035] Jujube: sweet, slightly bitter, slightly pungent, slightly sour, slightly salty, fragrant, enters the Taiyin spleen and Yangming stomach meridians; replenishes the essence of Taiyin Ji earth, transforms the Qi of Yangming Wu earth; produces fluid, moistens the lungs and removes dryness, nourishes blood and nourishes the liver and calms the wind, treats spleen and stomach deficiency, and regulates meridian deficiency; wood should rise straight, and bends to make it sour; metal should descend, and change to make it pungent; water should go up, and moisten it downwards to make it salty; fire should go down to help it, and burn it upwards to make it bitter; sourness will cause wood disease, so it should be pungent and dispersing; pungentness will cause metal disease, so it should be sour and contracting; saltiness will cause water disease, so it should be bitter and warming; bitterness will cause heart disease, so it should be salty and cold; if metal and wood do not follow their nature, disease will occur; if water and fire each follow their nature, disease will occur, and the treatment should be based on the flavor of the opposite palace. To be in harmony with the opposite; earth is in the middle of the four images, and has the harmony of the five flavors and the correctness of the five elements. It is not sour, pungent, bitter, or salty, and its taste is called sweet. It is not fishy, ​​smelly, burnt, or rotten, and its aroma is called fragrance. Taste is yin and energy is yang, yang is active and yin is quiet. With its sweet taste, yin is quiet and descends, and with its fragrant aroma, yang is active and rises. When it rises, Ji earth rotates to the left and water and wood do not sink, and when it descends, Wu earth rotates to the right and fire and metal do not go against the flow. The disease of the four images gives rise to the four flavors, and the earth's energy is weak. Jujube is pure, harmonious, and dignified, and has all the virtues of earth. Its aroma is sweet and fragrant, and it goes straight to the center and enters the spleen and stomach. Its sweetness is suitable for the stomach, and its fragrance is suitable for the spleen. In addition to the sweetness and fragrance, the four images It has all the flavors: its spiciness is good for the liver, its sourness is good for the lungs, its bitterness is good for the kidneys, and its saltiness is good for the heart; it nourishes the middle palace and nourishes all the children, and it is good for both the left and right sides, and it is also good for all directions without being contradictory. It is truly the best fruit in the world and a good medicine in the world; its flavor is strong and its texture is thick, so it is good at nourishing blood but not good at nourishing qi; ginseng nourishes the earth and qi to produce blood, while jujube nourishes the earth and blood to transform qi, so it is biased towards the earth, nourishing the spleen essence and nourishing the liver blood; all diseases of internal injury to the liver and spleen, deficiency of earth and dryness of wood, and blood depletion caused by wind are indispensable, and it is especially suitable for the time when external infection is released; it is the same as sweat and blood; the lung governs the defensive qi and controls the skin and fur, while the liver governs the nutrient blood and controls the meridians; the nutrient runs in the meridians and is the defensive qi. The root of the Wei meridians is the leaf of the Ying. Without the Wei, the Ying cannot be produced, and without the Ying, the Wei cannot be transformed. When it is brewed in the Wei and stored in the Ying, it becomes blood. When it is brewed in the Ying and discharged into the Wei, it becomes sweat. Although they have different names, they are actually the same. Therefore, it is said that if you take away sweat, you should not have blood, and if you take away blood, you should not sweat. In a stroke of the sun, the Wei Qi is restrained outside, the Ying is depressed and internal heat is generated. If the meridians are opened and the Ying is depressed, but the Ying Yin is not supplemented with jujube, the person will sweat and bleed to death, and the external infection will be gone but the internal injury will come. Therefore, Zhang Zhongjing uses it in all the prescriptions of cinnamon twig for stroke, which is a method of supplementing and purging at the same time. It is sweeter than fragrant, so it is less active and more quiet. It is used together with ginger and cinnamon to regulate its condensed Qi and make it flow to the internal organs and spread in the meridians. BRIEF DESCRIPTION OF THE DRAWINGS

[0036] Figure 1 A schematic diagram of the Luoshu of the Yi people in the invention;

[0037] Figure 2 This is a schematic diagram of the circular motion of the twelve meridian qi in ancient Chinese medicine;

[0038] Figure 3 It is a schematic diagram of the decoction method in the invention. DETAILED DESCRIPTION

[0039] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments.

[0040] Embodiment 1: The present invention provides a technical solution: a Chinese medicine composition for treating atopic dermatitis and a preparation method thereof, comprising the following specific constituent raw materials:

[0041] Roasted Licorice 15g, Raw Atractylodes 15g, Cinnamon Twig 10g, White Peony Root 15g, Paeonia Suffruticosa 5g, Polygonatum odoratum 5g, Red Dates 30g, Ginger 15g;

[0042] The specific preparation process is as follows:

[0043] Step 1: Use a dryer to dry all the above raw materials and reduce the humidity of the raw materials to 27.3%;

[0044] Step 2: Use a grinder to process the raw materials into powder, pass through a 150-mesh sieve, and grind for 36 minutes. The downward pressure of the grinder is set to 4.2N / cm 2 ;

[0045] Step 3: Grind the unscreened raw materials for a second time until they pass through a 100-mesh sieve;

[0046] Step 4: Add distilled water and mix them evenly with a stirrer. The mass ratio of the raw material to distilled water is 1.15:2, and the stirring speed is 35r / min;

[0047] Step 5: After stirring evenly, heat it to 62.7°C and continue stirring for 25 minutes;

[0048] Step 6: Heat the mixer evenly to 89.9°C and cook for 35 minutes;

[0049] Step 7: Add vegetable oil to the mixed material, and continue to stir and mix until it becomes viscous. The vegetable oil is tea oil, and the mass ratio of the vegetable oil to the mixed material is 1.45:4;

[0050] Step 8: Continue heating to reduce the water content to 36.8%;

[0051] Step 9: Get the Chinese medicine paste.

[0052] Embodiment 2: The present invention provides a technical solution: a Chinese medicine composition for treating atopic dermatitis and a preparation method thereof, comprising the following specific constituent raw materials:

[0053] Roasted Licorice 16g, Raw Atractylodes 16g, Cinnamon Twig 11g, White Peony Root 15g, Paeonia Suffruticosa 6g, Polygonatum odoratum 4g, Red Dates 28g, Ginger 14g;

[0054] The specific preparation process is as follows:

[0055] Step 1: Use a dryer to dry all the above raw materials and reduce the humidity of the raw materials to 20-30%;

[0056] Step 2: Use a grinder to process the raw materials into powder, pass through a 150-mesh sieve, and take 42 minutes. The downward pressure of the grinder is set to 4N / cm 2 ;

[0057] Step 3: Grind the unscreened raw materials for a second time until they pass through a 100-mesh sieve;

[0058] Step 4: Add distilled water and mix them evenly with a stirrer. The mass ratio of the raw material to distilled water is 1.3:2, and the stirring speed is 45r / min;

[0059] Step 5: After stirring evenly, heat it to 65°C and continue stirring for 30 minutes;

[0060] Step 6: Heat the mixer evenly to 92.4°C and cook for 50 minutes;

[0061] Step 7: Add vegetable oil to the mixed material, and continue to stir and mix until it becomes viscous. The vegetable oil is tea oil, and the mass ratio of the vegetable oil to the mixed material is 1.5:4;

[0062] Step 8: Continue heating to reduce the water content to 35-48%;

[0063] Step 9: Get the Chinese medicine paste.

[0064] The symptoms of insufficient release of wind and wood qi in the human body include difficulty urinating, constipation, lower abdominal pain, left abdominal pain, flank pain, delayed menstruation, etc.

[0065] Manifestations of excessive release of wind and wood energy in a person: excessive sweating, frequent urination, increased bowel movements, dizziness, tinnitus, fever, twitching, tremors, heavy menstruation, early menstruation, urticaria, etc.

[0066] The mechanism of Shaoyin monarch fire: water rises and fire descends, so fire does not cause heat; insufficient circulation leads to insufficient wood fire, excessive circulation leads to failure of the minister fire to descend;

[0067] The symptoms of insufficient circulation of the heart fire qi include cold, numbness, pain, stasis, confusion, etc.

[0068] Symptoms of excessive circulation of human heart fire: tongue pain, oral ulcers, sore throat, palpitations, irritability, chest tightness, etc.

[0069] Shaoyang Fire Pathogenesis: Fire does not descend, which is due to insufficient contraction of dry metal;

[0070] The symptoms of insufficient burning of the fire energy of the human phase: palpitations, lower body cold symptoms; (insufficient original energy)

[0071] The symptoms of excessive burning of the fire energy of the human phase (not descending): dry mouth, tongue pain, oral ulcers, sore throat, fever, palpitations, chest tightness, constipation, difficult urination, lower body cold, macules, etc.

[0072] The pathogenesis of Taiyin damp earth: dry earth is rare, damp earth is common; spleen and earth are not able to transport and transform, which leads to insufficient water and fire; spleen and earth rise, which means yang qi rises, and if yang is deficient, damp earth will not rise, and if spleen and earth do not rise, water and wood will sink;

[0073] The manifestations of insufficient movement and transformation of the earth energy in the human body include: abdominal distension, belching, poor appetite, indigestion, diarrhea, vomiting, acid reflux, cold limbs, edema, stranguria, fatigue, loose stools, etc.

[0074] The pathogenesis of Taiyang cold water: insufficient sealing and storage, which means that the metal energy is not restrained enough and the wood energy is released too much;

[0075] The heat of Taiyang Renshui disease is caused by the failure of the small intestine fire to rise; the cold of Shaoyin Kuishui disease is caused by the deficiency of water and fire;

[0076] Symptoms of insufficient storage of water qi in the human body: dizziness, fever, lower limb edema, etc.

[0077] Clinical symptoms of atopic dermatitis:

[0078] Typical eczematous rashes on non-flexural sites (scalp dermatitis, eyelid eczema, nipple eczema, vulvar eczema, nummular eczema, fingertip eczema, nonspecific hand or foot dermatitis / atopic winter foot, nail or periungual eczema, and eczematous rashes on other parts of the body); atypical eczematous rashes (pityriasis simplex, cheilitis, subauricular and postauricular / subnasal fissures, prurigo, dyshidrosis, papular lichenification variant);

[0079] Acute phase: rapid onset, short course, local erythema, accompanied by papulovesicles, small blisters or millet-sized papules, obvious exudation and erosion, severe itching, infants and young children show restless sleep at night and frequent scratching;

[0080] Subacute: Erythema is seen at the lesions, with dark color, accompanied by scales, scabs, and small papules; severe itching, with little erosion and exudation;

[0081] Chronic: dark skin color, hyperpigmentation or hypopigmentation, local skin hypertrophy, lichenification or infiltration, accompanied by scaling, roughness, dryness, and obvious itching symptoms;

[0082] According to the pathogenesis of "wet earth and stagnant wood, insufficient middle qi, abnormal wood qi dispersal, insufficient metal qi astringency", the treatment principle of "tonifying the middle, dispersing wood, balancing dispersal, astringing and lowering lung metal" is determined, and the commonly used classical prescription drugs are selected according to the corresponding medicinal properties for prescription composition;

[0083] Drugs that warm and tonify the middle: roasted licorice root, codonopsis, jujube, dried ginger, fresh ginger, etc.;

[0084] Earthy herbs: Atractylodes macrocephala, Atractylodes lancea, Poria cocos, Chinese yam, Alisma orientalis, Coix seeds, Tangerine peel, Pinellia ternata, etc.

[0085] Liver and gallbladder wood qi drugs: peony root, rehmannia root, angelica root, moutan bark, scutellaria root, bupleurum root, cinnamon twig, chuanxiong root, ebony root, mugwort leaf, etc.

[0086] Metal Qi medicines: Schisandra chinensis, Ophiopogon japonicus, Polygonatum odoratum, Platycodon grandiflorum, Apricot kernel, Bamboo leaf, Coltsfoot flower, Inula flower, etc.

[0087] According to the properties, flavors and effects of the drugs, the combined drugs are as follows: Atractylodes macrocephala, cinnamon twig, white peony root, peony bark, polygonatum odoratum, roasted licorice root, jujube, and ginger;

[0088] The composition above is not stable, because the Chinese medicine for replenishing the middle earth includes not only Atractylodes macrocephala and ginger, the medicine for liver and gallbladder wood qi includes not only cinnamon twig, moutan bark, etc., and the medicine for metal qi includes not only polygonatum, and whether the medicines will offset each other's effects; in response to this technical problem, the author used the theory of circular motion to decipher the prescription and compatibility rules of the "body and use" flavor of "Tangye Jingfa Tu" which had been lost for more than a thousand years, and used this principle to carry out the compatibility of medicine flavors to make the prescription more accurate, and finally determined the Chinese medicine composition mentioned in the present invention: 15 grams of roasted licorice, 15 grams of raw Atractylodes macrocephala, 10 grams of cinnamon twig, 15 grams of white peony root, 5 grams of peony bark, 5 grams of polygonatum, 30 grams of red dates, and 15 grams of ginger.

Claims

1. A Chinese medicine composition for treating atopic dermatitis, characterized in that: The specific ingredients include: Roasted licorice root, raw atractylodes, cinnamon twig, white peony root, peony bark, polygonatum, red dates, ginger; The specific proportions according to the quality of raw materials are as follows: Roasted licorice root 14-18g, raw white atractylodes 12-16g, cinnamon twig 8-12g, white peony root 12-17g, peony bark 4-8g, polygonatum 4-6g, red dates 25-35g, ginger 13-17g.

2. A Chinese medicine composition for treating atopic dermatitis according to claim 1, characterized in that: The proportions of various raw materials in the Chinese medicine composition are as follows: 15g of roasted licorice root, 15g of raw white atractylodes, 10g of cinnamon twig, 15g of white peony root, 5g of peony bark, 5g of polygonatum, 30g of red dates, and 15g of ginger.

3. A Chinese medicine composition for treating atopic dermatitis according to claim 1, characterized in that: The proportions of various raw materials in the Chinese medicine composition are as follows: Roasted licorice root 16g, raw white atractylodes 16g, cinnamon twig 11g, white peony root 15g, peony bark 6g, polygonatum odoratum 4g, red dates 28g, and ginger 14g.

4. A method for preparing a Chinese medicine composition for treating atopic dermatitis as claimed in any one of claims 1 to 3, characterized in that: The specific steps include: Step 1: Use a dryer to dry all the above raw materials and reduce the humidity of the raw materials to 20-30%; Step 2: Use a grinder to process the raw materials into powder, pass through a 150-200 mesh sieve for 30-45 minutes, and set the downward pressure of the grinder to 3-4.5N / cm 2 ; Step 3: Grind the unscreened raw materials for a second time until they pass through a 100-mesh sieve; Step 4: Add distilled water and mix them evenly with a stirrer. The mass ratio of the raw material to the distilled water is 1-1.3:2, and the stirring speed is 30-45r / min; Step 5: After stirring evenly, heat it to 55-70°C and continue stirring for 20-30 minutes; Step 6: Heat the mixer evenly to 80-95°C and cook for 30-50 minutes; Step 7: Add vegetable oil to the mixture and continue stirring until it becomes viscous; Step 8: Continue heating to reduce the water content to 35-48%; Step 9: Get the Chinese medicine paste.

5. A method for preparing a Chinese medicine composition for treating atopic dermatitis according to claim 4, characterized in that: The vegetable oil in step seven is tea oil, and the mass ratio of the vegetable oil to the mixed material is 1-1.5:4.

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