Oral flora marker for early warning plateau polycythemia and kit thereof
By using the combination of oral flora markers to build joint diagnostic indicators, the problem of poor early warning diagnosis of HAPC in the prior art was solved, accurate diagnosis of HAPC patients and large-scale population screening were achieved, and health damage and life risks were reduced.
CN119662865APending Publication Date: 2025-03-21THE 940TH HOSPITAL OF THE CHINESE PEOPLES LIBERATION ARMY JOINT LOGISTICS SUPPORT FORCE
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Patent Information
- Application Number
- CN202411897421.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-23
- Publication Date
- 2025-03-21
AI Technical Summary
Technical Problem
The prior art cannot effectively conduct early warning diagnosis of HAPC, and the existing indicators have poor accuracy and sensitivity for early warning diagnosis of HAPC.
Method used
Combined diagnostic indicators were constructed to distinguish HAPC patients from plateau healthy populations by discovering and utilizing combinations of oral flora markers, including Muribaculaceae, Abiotrophia, and Granulicatella.
Benefits of technology
It has achieved accurate diagnosis of HAPC patients, with high sensitivity and specificity, and can support early warning and large-scale population screening, reducing the health damage and life risks caused by HAPC.
✦ Generated by Eureka AI based on patent content.
Abstract
The invention discloses oral flora marker types, an oral flora marker combination and application of the oral flora marker combination in preparation of a kit for early diagnosis of high altitude polycythemia (HAPC), and particularly relates to the technical field of biological detection. An early diagnosis model constructed based on the oral flora finds that the provided oral flora marker combination can specifically recognize HAPC patients from plateau healthy controls. The kit is used for disease early warning and early diagnosis of HAPC, and has the advantages of high acceptability, non-invasive property, convenience, high sensitivity and high specificity. The marker is suitable for carrying out large-scale HAPC early warning and early diagnosis on crowds which are chronic exposed to plateau regions, and guiding prevention and control treatment of HAPC, so that health damage and life risks caused by HAPC are reduced.
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