Edible biological scaffold and preparation method and application thereof

By combining chitosan, ribose and soy dietary fiber with soy protein amyloid fiber, the shortcomings of existing biological scaffolds in terms of mechanical properties and porosity are solved, and the cell proliferation ability is significantly improved, providing an environment more suitable for cell growth.

CN119736233APending Publication Date: 2025-04-01HANGZHOU VOCATIONAL & TECHN COLLEGE
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Patent Information

Application Number
CN202411863043.2
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-12-17
Publication Date
2025-04-01

AI Technical Summary

Technical Problem

The existing edible biological scaffolds have shortcomings in mechanical properties, porosity and cell proliferation ability, resulting in poor cell adhesion and proliferation effects.

Method used

By combining chitosan, ribose and soy dietary fiber with soy protein amyloid fiber, chitosan provides positive charge, ribose and dietary fiber to provide oligosaccharides, promoting soy protein Maillard reactions, thereby improving the mechanical properties and porosity of the scaffold.

Benefits of technology

It significantly improves the mechanical properties, porosity and cell proliferation ability of the biological scaffold, provides an environment that is more suitable for cell growth, and improves cell adhesion and proliferation characteristics.

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Abstract

The present invention provides an edible biological scaffold and a preparation method and application thereof. Soy protein amyloid fibers are prepared from soybean protein, and chitosan, ribose and soybean dietary fiber are added thereto to optimize the composition, so as to obtain an edible biological scaffold with excellent mechanical properties, and the porosity, cross-linking degree and swelling degree are more suitable for cell growth. The materials are all food-grade ingredients, and no chemical reagents are added during the reaction process, so the edible safety can be guaranteed. When used for C2Cl2 cell culture, the scaffold shows good cell compatibility, and experimental results show that the scaffold is beneficial to improving the cell adhesion and proliferation ability. The scaffold preparation process is simple, and the raw materials are of high value and low cost, so the scaffold has greater application potential in the field of cell cultured meat.
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