A method for efficiently preparing vitamin B1
Through multiple reaction and treatment steps, an efficient and low-cost vitamin B1 synthesis method was prepared, which solved the problems of complex operation, high cost and low yield in the prior art, and achieved efficient preparation effects suitable for industrial production.
CN119751436APending Publication Date: 2025-04-04SHANXI YUNPENG PHARMA
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Patent Information
- Application Number
- CN202411844984.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-15
- Publication Date
- 2025-04-04
AI Technical Summary
Technical Problem
The existing vitamin B1 synthesis methods have problems such as complex operation, high cost and low yield, and it is difficult to meet the needs of industrial production.
Method used
A method for efficient preparation of vitamin B1 is proposed. Through a multi-step reaction process, including reactions of formic acid, 4-amino-5-cyano-2-methylpyrimidine, ranny nickel and methanol, followed by multiple filtration, concentration, pH adjustment, distillation and vacuum drying, etc., to finally obtain the finished vitamin B1 product.
Benefits of technology
The overall operation of this method is simple, with few steps and high yield. It is suitable for industrial production, reduces production costs and achieves efficient preparation of vitamin B1.
✦ Generated by Eureka AI based on patent content.
Abstract
The invention discloses a method for efficiently preparing vitamin B1. The method comprises the following steps: obtaining an alcoholic hydroxyl group from 4-amino-5-cyano-2-methylpyrimidine under the action of Raney nickel and formic acid, and then reacting the alcoholic hydroxyl group with thionyl chloride, and finally reacting the alcoholic hydroxyl group with thiothiazole to obtain a finished vitamin B1 product. The method for preparing vitamin B1 provided by the invention has simple overall operation, fewer process steps, high yield, is suitable for industrial production, reduces production costs, and can realize efficient preparation of vitamin B1.
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