A method for fermenting Cistanche deserticola and fermented products thereof

By fermenting Cistanche with Bacillus subtilis subsp.subtilis CEGF012, the problems of low bioavailability of Cistanche and low dissolution rate of phenylethanol glycosides were solved, and the effective ingredients were significantly improved and efficient extraction was achieved.

CN119753062APending Publication Date: 2025-04-04HUBEI CHANGE BIOLOGY CO LTD
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Patent Information

Application Number
CN202411946403.5
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-12-26
Publication Date
2025-04-04

AI Technical Summary

Technical Problem

Cistanche has low bioavailability, and it is difficult for the existing technology to directly ferment with microorganisms. It is necessary to first dissolve enzymatically or add additional glycogen to ferment normally, resulting in a low dissolution rate of the active ingredient phenylethanol glycosides.

Method used

Cistanche was fermented with Bacillus subtilis subsp.subtilis CEGF012 with storage number CCTCC NO:M 20241702, and fermented products rich in phenylethanolamine were obtained through water extraction or alcohol extraction.

Benefits of technology

It significantly improves the dissolution rate of phenylethanolamines in Cistanche, which is conducive to the preparation of Cistanche fermentation products rich in phenylethanolamines.

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Abstract

The invention relates to a method for fermenting Cistanche deserticola and a fermented product thereof. The method comprises the step of fermenting Cistanche deserticola by using Bacillus subtilis subsp.subtilis CEGF012 with a preservation number of CCTCC NO:M 20241702. The method uses Cistanche deserticola as a raw material and adopts Bacillus subtilis subsp.Subtilis CEGF012 for fermentation, so as to promote the extraction of phenylethanol glycosides as an effective component in Cistanche deserticola. Compared with unfermented Cistanche deserticola, the dissolution rate of phenylethanol glycosides in Cistanche deserticola fermented by the method is significantly increased whether it is water extraction or alcohol extraction, and the bioavailability of phenylethanol glycosides as an effective component in Cistanche deserticola can be improved after fermentation by using Bacillus subtilis subsp.subtilis CEGF01.
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