High-adhesion sterile hydrogel patch and preparation method thereof

The double-crosslinked hydrogel preparation method solves the shortcomings of hydrogel products in high adhesion and water washability, and achieves high adhesion, low water loss rate and low swelling performance, which is suitable for large-area wounds and repeated wear in sterile environments.

CN120241669BActive Publication Date: 2025-09-30SHANDONG YONGJU MEDICAL TECH
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Patent Information

Application Number
CN202510735042.8
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2025-06-04
Publication Date
2025-09-30
Estimated Expiration
2045-06-04

AI Technical Summary

Technical Problem

Existing hydrogel products have shortcomings in maintaining high adhesion and low water loss rate, which limits their application in areas such as large-area wounds or repeated wear. Traditional methods cannot achieve reusability and water-resistant properties.

Method used

A double cross-linking system is adopted, combining chemical cross-linking and radiation cross-linking, using sodium polyacrylate and aluminum glycolate as chemical cross-linking agents, and polyvinyl alcohol and polyvinyl pyrrolidone as radiation cross-linking agents. By adjusting the cross-linking ratio and component ratio, a stable double network structure is formed.

Benefits of technology

It achieves high adhesion, low water loss rate and low swelling performance. The product can be washed and reused repeatedly, is suitable for large wounds and repeated wearing, and is suitable for sterile environments.

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Abstract

The present invention belongs to the technical field of sterile hydrogel patches, and specifically relates to a high-adhesion sterile hydrogel patch and a preparation method thereof. The preparation method of the high-adhesion sterile hydrogel patch is as follows: the high-adhesion sterile hydrogel patch has a three-layer structure, with a gel layer in the middle, a PE-type release film on the upper layer, and a PE plastic sheet on the lower layer. The high-adhesion sterile hydrogel patch and the preparation method thereof of the present invention adjust the formula of the high-adhesion sterile hydrogel patch and utilize a double cross-linking system to ensure the strength and toughness of the hydrogel while making it have high viscosity, low water loss rate and low swelling performance, and the product can be repeatedly washed and worn. In addition, it also has a good cold compress analgesic effect; the present invention also provides a preparation method thereof, the preparation process is simple, and the whole process is non-toxic and harmless.
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