Preparation method of coreopsis tinctoria and lithospermum erythrorhizon traditional Chinese medicine lipstick with anti-inflammatory and repairing effects

The chrysanthemum compost was extracted through liquid nitrogen freeze-breaking and supercritical CO2 extraction technology, and core-shell microspheres were constructed and film-forming was formed using the choke-axel polysaccharide enzyme to respond to film, which solved the anti-inflammatory repair problem of Chinese herbal lipstick in extreme environments, achieving efficient sustained release and protective effects of active ingredients.

CN120514643AActive Publication Date: 2025-08-22NAIMAN BANNER MONGOLIA MEDICAL HOSPITAL
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Patent Information

Application Number
CN202511025202.6
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-07-24
Publication Date
2025-08-22
Estimated Expiration
2045-07-24

AI Technical Summary

Technical Problem

The existing Chinese herbal lipsticks have poor anti-inflammatory and repair effects in high cold, strong ultraviolet rays and sandstorms. The extraction efficiency of active ingredients is low. The substrate is prone to break at low temperatures. It lacks anti-UV components and has a single effect, which cannot meet the needs of plateau areas.

Method used

The components of cypress chrysanthemum compost were extracted by liquid nitrogen frozen crushing combined with supercritical CO2 extraction technology, and core-shell microspheres copolymerized by camel fat wax and cypress flavonoids were constructed. The film was formed by using the choke-axogenic polysaccharide enzyme to form a bioadhesive film with low moisture permeability, and ingredients such as roasted licorice were added to enhance anti-inflammatory and protective properties.

Benefits of technology

Maintain efficient anti-inflammatory repair performance in extreme environments, good sustained release of active ingredients, significantly improved protective effect, stable SPF value, high repair rate of chapped lips, and significant anti-sand, dust and ultraviolet rays.

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Abstract

The invention relates to a preparation method of a coreopsis tinctoria and lithospermum erythrorhizon traditional Chinese medicine lipstick with anti-inflammatory and repairing effects. Aiming at the problems that active ingredients of the traditional Chinese herbal medicine lipstick are easy to degrade, easy to break at low temperature, insufficient in anti-inflammatory repairing effect and the like, a freezing crushing-supercritical extraction-microsphere self-assembly process is initiated and comprises the following steps: 1, quick-freezing coreopsis tinctoria, lithospermum erythrorhizon and roselle in liquid nitrogen, performing high-pressure micro-jet crushing, and combining cetyltrimethylammonium bromide / supercritical CO2 extraction, so that the yield of alkannin is increased; 2, injecting the extract into an olive oil carrier containing camel fat wax, and self-assembling to form core-shell microspheres to realize lip temperature triggered self-repairing; and 3, cynomorium songaricum polysaccharide is added to react with salivary enzyme to generate a biological adhesive film, and the TNF-alpha inhibition rate is increased by cooperating with the honey-fried licorice root extract, the sea buckthorn seed oil and the like. The lipstick is suitable for lip protection in extreme environments such as high cold, sand storm and plateau strong ultraviolet rays, and fills the technical blank of Chinese herbal medicine lipsticks in the field of molecular-level slow release and intelligent response repair.
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