Portable phototherapy system and method of using same

Abstract

A phototherapy system includes a garment housing configured to be worn by an infant and including a first pocket disposed on an inner surface thereof. The phototherapy system may include an illumination panel configured to be removably disposed in the first pocket. The garment may be configured to position and / or orient the illumination panel such that a first portion of the illumination panel is aligned with the back of the infant and a second portion of the illumination panel is aligned with the chest of the patient. The illumination panel may include a plurality of light sources arranged in a grid and coupled to a circuit board. The illumination panel and / or the circuit board can be arranged in a protective shell. The protective shell may include a plurality of openings that can reduce the overall weight of the illumination panel and / or affect the optical path or irradiance of at least one of the plurality of light sources. The phototherapy system may include a controller configured to adjust an output of the illumination panel according to at least one user input or acquired data.

Description

Technical Field

[0001] The invention disclosed herein relates to a garment incorporating a phototherapy system for providing phototherapy to a patient, and a method of using it. Background Technology

[0002] Phototherapy delivers light to a patient and can be used to treat a variety of conditions. For example, it can be used to alleviate symptoms of psoriasis and eczema. Phototherapy is safe for all ages and is therefore a common treatment for neonatal jaundice. However, traditional infant phototherapy systems have common problems such as dehydration, hypothermia, the need to wear an eye shield, lack of parent-child bonding, interruption of breastfeeding during treatment, and interruption of treatment during breastfeeding. Summary of the Invention

[0003] The purpose of this invention is to provide a portable and comfortable phototherapy system that uses light within a specific wavelength range to cover the surface area of ​​an infant's torso below the head and neck. The irradiance level can be adjusted according to treatment needs, allowing the infant to be breastfed while receiving phototherapy. The system is battery-powered, and the infant's feeding and holding will not affect the treatment, thereby promoting parent-child interaction and avoiding adverse side effects on the infant (such as hypothermia, dehydration, and risk of eye damage).

[0004] The present invention solves the technical problem by adopting the following technical solution: A device for providing phototherapy to an infant may include: an openable clothing shell that allows an infant to be placed therein. The clothing shell includes a first pocket disposed on its inner surface, the first pocket defining a space for removably placing a light-emitting panel. The light-emitting panel includes a plurality of light sources configured to emit light at predetermined wavelengths and intensities. The space of the first pocket extends from the back to the front of the clothing shell such that when the infant is placed inside the clothing shell and the light-emitting panel is placed in the first pocket, a first portion of the light-emitting panel is aligned with the infant's back, and a second portion is aligned with the infant's chest. The clothing shell may also include a second pocket, the second pocket defining a space for accommodating a battery and a controller operatively connected to the light-emitting panel. The clothing shell may also include a mesh structure forming part of it, configured to allow light or heat emitted by the light-emitting panel to escape from the clothing shell through the mesh structure.

[0005] Preferably, the garment shell also includes: A first zipper extends along the front side of the garment shell, the first zipper being operable to open the garment shell to allow an infant to be placed inside the garment shell.

[0006] Preferably, the garment shell also includes: A movable flap is attached to one side of the garment shell. The movable flap has a first state in which the flap does not cover the mesh structure, and a second state in which the flap covers the mesh structure to block light emitted from the light-emitting panel from escaping through the mesh structure.

[0007] Preferably, the movable flap can be moved between a first state and a second state by a user holding an infant.

[0008] Preferably, when the baby is placed inside the clothing shell, the mesh structure is at least partially aligned with the baby's abdomen.

[0009] Preferably, the illumination panel includes one or more sensors coupled thereto, the one or more sensors being configured to monitor at least one of the infant's biosignals or the internal environment of the clothing shell.

[0010] Preferably, the infant's biosignals may include the infant's bilirubin levels.

[0011] Preferably, the internal environment of the garment shell includes at least one of the following: the location of the garment shell, the temperature inside the garment shell, the temperature of the light panel, or the humidity inside the garment shell.

[0012] Preferably, the outer shell of the garment comprises a double layer of cotton fabric.

[0013] Preferably, a portion of the first pocket includes a transparent material, allowing light emitted from the light-emitting panel to reach the baby's skin when the baby is placed inside the garment shell.

[0014] Preferably, the garment shell further includes: a pair of arm openings configured for an infant's arm to pass through, each arm opening being adjustable in size such that the outer edge of each arm opening fits snugly against the infant's arm to prevent light from leaking from the interior of the garment shell through the pair of arm openings; and a neck opening configured for an infant's head to pass through, wherein the neck opening includes a light-blocking collar to prevent light from leaking from the interior of the garment shell through the neck opening.

[0015] Preferably, the outer shell of the clothing is a swaddle.

[0016] Preferably, the plurality of light sources include light-emitting diodes (LEDs). Preferably, the garment shell includes an active heat dissipation mechanism, which includes a fan.

[0017] The present invention also provides an apparatus comprising: a flexible circuit board; a plurality of light sources arranged in an ordered configuration, the plurality of light sources being connected to a first side of the flexible circuit board; and a flexible protective shell connected to the flexible circuit board and the plurality of light sources. The protective shell is disposed on a second side of the plurality of light sources and a second side of the flexible circuit board, and the flexible protective shell includes a plurality of grooves disposed between at least partially adjacent light sources. The plurality of light sources are configured to be close to and emit light onto the surface of an infant's skin. The plurality of light sources have viewing angles and are spaced apart from each other, such that the light intensity emitted onto the infant's skin surface is higher than a predetermined threshold.

[0018] Preferred; the viewing angle of each of the multiple light sources is between 0 and 180 degrees.

[0019] Preferably, the protective shell comprises at least one of silicone or polyvinyl chloride (PVC).

[0020] Preferably, the protective shell includes a first layer and a second layer connected together. The first layer is disposed on the second side of the light source, and the second layer is disposed on the second side of the flexible circuit board. The first layer defines a first portion of a plurality of openings, and the second layer defines a second portion of a plurality of openings.

[0021] Preferably, the protective shell covering the second side of the multiple light sources is at least partially transparent.

[0022] Preferably, the protective shell further includes a light-reflecting layer disposed on the second side of the flexible circuit board, which reflects stray light from multiple light sources back to the baby's skin surface.

[0023] Preferably, the protective shell further includes a light-absorbing layer disposed on the second side of the flexible circuit board, which absorbs stray light from multiple light sources.

[0024] Preferably, the predetermined threshold of the light intensity is at least 30 µW / cm² / nm (microwatts per square centimeter per nanometer).

[0025] Preferably, the device is configured to be housed in a fully portable swaddle, with the circuit board coupled to a controller and a battery, both of which are configured to be housed within the swaddle.

[0026] Preferably, the plurality of openings reduce the total weight of the protective shell.

[0027] Preferably, the ordered configuration is a grid.

[0028] Preferably, the opening is located outside the light cone defined by the light source's viewing angle.

[0029] Preferably, the plurality of light sources include light-emitting diodes (LEDs).

[0030] The present invention also provides a system comprising: a light-emitting panel configured to be placed within an infant's clothing, the light-emitting panel being configured to emit light during phototherapy to treat an infant's illness; one or more sensors disposed within the clothing; and a controller connected to the light-emitting panel, the one or more sensors, and an external device for operation, the controller being configured to: receive information related to the phototherapy process from the external device; send signals to the light-emitting panel to cause the light-emitting panel to emit light according to the information related to the phototherapy process; monitor one or more signals via the one or more sensors, including at least the infant's biosignals or signals related to the internal environment of the clothing; determine whether one or more signals exceed a predetermined threshold; and adjust the output of the light-emitting panel when at least one signal exceeds the predetermined threshold.

[0031] Preferably, the information related to the phototherapy process includes at least one of the wavelength of light, the intensity of light, or the duration of the phototherapy process.

[0032] Preferably, the internal environment of the garment includes at least one of the following: the location of the garment, the internal temperature of the garment, the temperature of the light-emitting panel, or the internal humidity of the garment.

[0033] Preferably, the controller is configured to automatically turn off the light panel when at least one of the internal temperature of the garment or the temperature of the light panel exceeds a predetermined threshold.

[0034] Preferably, the disease is jaundice, and the infant's biosignals include bilirubin levels.

[0035] Preferably, the controller is configured to adjust the intensity of the light emitted by the illumination panel according to the bilirubin level.

[0036] Preferably, the one or more signals include the amount of time the light panel has been emitting light.

[0037] Preferably, the controller is further configured to send information related to the completed phototherapy process to an external device for storage.

[0038] Preferably, the external device is configured to receive user input corresponding to information related to the phototherapy process.

[0039] Preferably, the clothing is a swaddle blanket.

[0040] Preferably, the illumination panel includes an LED panel. Attached Figure Description

[0041] Figure 1 A schematic block diagram of a system for providing phototherapy to a patient, according to an embodiment of this disclosure; Figure 2 A schematic block diagram of a light-emitting panel for providing light to a patient's skin, according to an embodiment of this disclosure; Figure 3 A schematic block diagram of a garment housing for housing a light-emitting panel, the garment housing being used to provide light therapy when worn by an infant, according to an embodiment of this disclosure; Figure 4 An outer casing for clothing worn by an infant is provided, the outer casing being configured to house a light-emitting panel to provide light therapy to the infant, according to embodiments of the present disclosure.

[0042] Figures 5A-5B Front and rear views are shown, respectively, of a garment housing configured to house a light-emitting panel for providing light therapy to an infant, according to embodiments of this disclosure. Figure 5C The photograph shows a pocket with a removable light-emitting panel, according to an embodiment of this disclosure; Figures 6A-6B The front and back of a garment housing configured to house a light-emitting panel are shown respectively, the garment housing being used to provide light therapy to an infant, according to an embodiment of this disclosure; Figure 7 The present disclosure provides a schematic diagram of a light-emitting panel including multiple light sources and a protective casing, according to an embodiment of the present disclosure.

[0043] Figure 8 An analytical diagram of a light-emitting panel including multiple light sources and a protective casing, according to an embodiment of this disclosure; Figures 9A-9B Different structural configurations of the illumination panel are shown according to embodiments of this disclosure; Figures 10A-10B Different structural configurations of the illumination panel are shown according to embodiments of this disclosure; Figure 11 To illustrate a protective housing configured for connection with a light-emitting panel, the protective housing includes a light-absorbing layer, according to an embodiment of this disclosure; Figure 12A This is a schematic diagram of a protective housing including an opening disposed on a light source, according to an embodiment of the present disclosure; Figure 12B A schematic diagram of a protective housing including openings disposed between adjacent light sources, according to an embodiment of the present disclosure; Figure 13 A schematic diagram of a light-emitting panel having a shape corresponding to a pocket on a garment shell, according to an embodiment of the present disclosure; Figures 14A-14C An example user interface for controlling a light-emitting panel is shown, the phototherapy system including the user interface, according to an embodiment of this disclosure; Figure 15 A flowchart of a method for providing phototherapy using a phototherapy system, according to embodiments of this disclosure. Detailed Implementation

[0044] The technical solution of the present invention will be further described below with reference to the embodiments and accompanying drawings.

[0045] Example Phototherapy (also known as light exposure therapy) can be used to treat a variety of conditions, including skin diseases such as psoriasis, eczema, vitiligo, and mycosis fungoides, as well as jaundice. According to the American Academy of Pediatrics (AAP) and other literature, approximately 60% of infants born in the United States each year develop clinical jaundice or hyperbilirubinemia. Jaundice or hyperbilirubinemia is caused by increased bilirubin production and decreased excretion in newborns. In some infants, bilirubin levels can continue to rise to dangerous levels if left untreated. Excessive bilirubin can lead to a brain disease called kernicterus and bilirubin-induced neurological disorder (BIND), which can even be fatal.

[0046] When the human body is exposed to light with specific parameters (such as wavelength and intensity), unconjugated bilirubin in the body can be converted into compounds that are more easily excreted through urine and feces. The effectiveness of phototherapy depends on four main factors: (1) irradiance or light intensity; (2) color or wavelength of light; (3) skin coverage or exposed area; and (4) exposure time or duration.

[0047] Existing phototherapy systems for infants have several drawbacks, including adverse side effects on newborns (such as hypothermia, dehydration, and risk of eye damage), lack of portability, insufficient comfort, bulky light sources, low irradiance levels, and / or limited skin coverage. For example, existing phototherapy methods for treating neonatal hyperbilirubinemia involve placing the newborn completely naked with an eye shield to protect their eyes under a light source (e.g., a blue fluorescent lamp). These systems are not only bulky and immobile, but the blue fluorescent light source cannot provide sufficient heat to the infant, potentially leading to hypothermia. To prevent hypothermia, more fluorescent lamps of different wavelengths can be added to the system to generate sufficient heat; however, this can lead to dehydration. Other challenges exist with phototherapy systems using other light sources, such as trade-offs between appropriate irradiance of the light panel, system portability, system comfort, and light coverage. For example, a phototherapy system with irradiance suitable for treating infant jaundice may lack sufficient skin coverage. Alternatively, smaller and / or non-fixed phototherapy systems may not produce adequate irradiance levels.

[0048] In contrast, embodiments of this disclosure relate to a phototherapy system comprising a light-emitting panel configured to be detachably housed within a garment housing. In some embodiments, the garment may be a swaddle for containing an infant. The light-emitting panel may include multiple light sources (e.g., light-emitting diodes (LEDs), organic light-emitting diodes (OLEDs), fiber optic cables, etc.). The garment may be configured to position and / or orient the light-emitting panel toward a portion of the infant's body. In some embodiments, the garment may include a pocket for detachably housing the light-emitting panel. The pocket may include a transparent material that allows light emitted from the light-emitting panel to contact the infant's skin. In some embodiments, the garment may include a second pocket for housing a power source (e.g., a portable and / or rechargeable battery) and / or a controller. In some embodiments, the garment housing may be configured to house a portable power source and controller, making the phototherapy system entirely portable. In some embodiments, the phototherapy system of this disclosure may allow the infant to be breastfed while receiving phototherapy and promote parent-child interaction.

[0049] Embodiments of this disclosure may include a light-emitting panel configured to generate appropriate irradiance during jaundice treatment while remaining lightweight (e.g., weighing less than about 12 ounces and covering an area of ​​about 1300 square centimeters), ensuring infant comfort, and operating with the required power from a small battery pack without disturbing the infant. The phototherapy system of this disclosure may include a light-emitting panel comprising a plurality of ordered LEDs connected to a circuit board. The light-emitting panel and / or circuit board may be housed in a protective housing. The protective housing may include multiple openings (e.g., recesses, spaces, through-holes, pores, etc.) to reduce the overall weight of the light-emitting panel. In some embodiments, each opening may serve as a convex lens facing the skin. For example, the surface forming the opening on the side closest to the skin may be convex. The protective housing may be used to prevent the light-emitting panel and associated circuitry from being exposed to harmful substances such as liquids, and / or to protect the infant from the effects of the light-emitting panel circuitry. In some embodiments, the protective housing may serve as a light guide, directing light emitted from the light source to the infant's skin, thereby reducing stray light (e.g., light that does not reach the infant's skin).

[0050] Furthermore, embodiments of this disclosure relate to a phototherapy system including a controller configured to control the light supplied by a light irradiation panel based on user input or acquired data. In some embodiments, the phototherapy system may include one or more sensors operatively connected to the light irradiation panel and the controller. The controller may be configured to receive information, including at least sensor data or user input (e.g., from an external device), and adjust the output of the light irradiation panel based on the received information. In some embodiments, the controller may be configured to reduce the irradiance level of the light source and / or turn off the light irradiation panel. In some embodiments, the controller may automatically (e.g., without user input) adjust the output of the light irradiation panel.

[0051] The phototherapy system disclosed herein can utilize LEDs, OLEDs, and / or optical fibers to distribute appropriate light over a large area of ​​the infant's body. This phototherapy system is efficient, low-cost, lightweight, baby-friendly, durable, and easy to install and use. It consumes relatively low power via a rechargeable battery and can be used outside of hospitals or while traveling. The system minimizes discomfort for both the infant and caregivers and can output light within one or more predetermined wavelength ranges to treat related conditions (e.g., jaundice). The system may include a real-time monitoring system (RTMS), a controller, a communication system, and one or more user interfaces (UIs). Therefore, the system can communicate with the user and other devices and systems, enabling rapid user response (e.g., remote response). The phototherapy provided by this system causes minimal side effects such as hypothermia, dehydration, or rashes, and requires no eye protection. The system's ability to provide appropriate phototherapy while maintaining low power consumption allows it to operate on battery power, so infant feeding and holding do not interfere with treatment, thus promoting parent-child interaction.

[0052] Figure 1 This is a schematic block diagram of a phototherapy system 1000 for providing phototherapy to a patient 102, according to embodiments of the present disclosure. As shown, the phototherapy system 1000 includes a clothing shell 100 (e.g., swaddle, pajamas, shirt, dress, vest, bib, etc.). In some embodiments, the clothing shell 100 can be reused and / or washed between uses. The clothing shell 100 may be configured to open to allow the patient 102 (e.g., an infant / newborn) to be placed therein. For example, the clothing shell 100 may include a fastener (e.g., zipper, Velcro, button, strap, clip, etc.) extending along the front side of the clothing shell 100 and configured to open the clothing shell 100 to allow the patient 102 to be placed therein and / or to allow the clothing shell 100 to be positioned around the patient 102. The fastener may include a two-way zipper to allow the clothing 100 to be opened from the top and / or bottom (e.g., to facilitate changing a baby's diaper without interrupting treatment). For example, a user can pull the zipper from the top end (e.g., near the baby's head) to the bottom end (e.g., near the baby's feet) of the garment shell 100, and / or from the bottom end to the top end.

[0053] In some embodiments, the garment shell 100 includes a breathable portion 130 disposed on and / or forming part thereof. In some embodiments, the breathable portion 130 may include a breathable fabric, such as a mesh structure, a perforated fabric, a lightweight fabric, etc. The breathable portion 130 may be configured to allow the release of light and / or heat emitted by the light-emitting panel. In some embodiments, the garment shell 100 may also include an active heat dissipation mechanism, such as a fan, blower, cooling material, etc. The active heat dissipation mechanism may be configured to expel hot air from inside the garment 100 and introduce cool air into the garment 100. In some embodiments, the garment 100 may optionally include a movable portion (e.g., a movable flap). The movable flap may be attached to one side of the garment 100. For example, the movable flap may have a first state in which the flap does not cover the breathable portion 130, and a second state in which the flap covers the breathable portion 130 to prevent light emitted by the light-emitting panel 110 from leaking out through the breathable portion 130. The garment 100 may also include a pair of armholes and a neck opening, allowing the infant to wear the garment 100. In some embodiments, the bottom of the garment 100 (e.g., a swaddle) may be closed. Further details of the garment 100 will be provided below. Figure 3 As described in the text.

[0054] The phototherapy system 1000 may include a light-generating panel 110 (i.e., a light-generating panel assembly (LPPA)) configured to be detachably placed within at least a portion of a garment shell 100. In some embodiments, the garment shell 100 may include one or more pockets disposed on its inner and / or outer surfaces. For example, the garment shell 100 may include a first pocket disposed on its inner surface defining a space for at least temporarily placing the light-generating panel 110. The light-generating panel 110 may be formed or include a shape corresponding to the space in the first pocket. In some embodiments, the first pocket may be configured to align and / or cover a target area of ​​the patient 102 when placed therein. For example, the first pocket may be configured to position the light-generating panel 110 above or near a portion of the patient 102's torso (e.g., the back and / or chest). In some embodiments, the light-generating panel 110 may be positioned to provide 360-degree illumination to the upper body and illumination to the entire back of the lower body. In some embodiments, the light panel 110 and / or clothing 100 may be configured such that the light emitted by the light panel 110 covers or contacts at least 1% to 100% of the infant's body. The light panel 110 may include multiple light sources (e.g., LEDs, OLEDs, optical fibers, etc.) configured to emit light onto the skin of the patient 102 when the light panel 110 is placed in the clothing casing 100 (e.g., in the first pocket of the clothing casing 100).

[0055] In some embodiments, multiple light sources may be arranged in an ordered manner (e.g., a grid, staggered grid, repeating pattern, etc.). Multiple light sources may be connected to a circuit board configured to electrically connect the light sources to a power supply 145 and / or a controller 150 with the correct polarity. The circuit board may be configured to control the output of the light source 112 based on signals from the power supply 145 and / or the controller 150. In some embodiments, the electrical connections of the phototherapy system 1000 may include heat dissipation components, such as copper wires, copper blocks, and / or graphene films attached to one or both sides of the electrical connection or circuit. In some embodiments, electrical connections in the light-emitting panel 110 may include these heat dissipation components. The circuitry of the phototherapy system 1000 may all include electrical connectors compliant with medical treatment requirements.

[0056] The light panel 110 may also include a protective shell configured to be disposed on and / or around a portion of the light source 112 and the circuit board 116. The protective shell may be disposed on one or both sides of the light source and the circuit board and may be configured to protect electronic components from harmful substances and / or protect the patient from the electronic components. In some embodiments, the protective shell may include multiple openings. In some embodiments, the light panel 110 may be configured to maintain a space between the light panel 110 and the infant's chest. For example, the light panel 110 may form a tent-like structure, lifting at least a portion of the light panel 110 away from the infant's chest. Therefore, the light panel 110 exerts minimal weight on the infant's chest, thus providing a safer and more comfortable condition during phototherapy. Further details of the light panel 110 will be provided below. Figure 2 As described in the text.

[0057] The phototherapy system 1000 may also include a controller 150, a power supply 145, and optionally include one or more sensors 140, a communication interface 152, a memory 154, and one or more external devices 180. In some embodiments, the clothing shell 100 may include one or more pockets that define spaces configured to at least temporarily accommodate the controller 150 and / or the power supply 145 (and / or the memory 154 and communication interface 152). For example, the clothing shell 100 may include a second pocket that defines a space for simultaneously accommodating the controller 150 and the power supply 145. In this way, the phototherapy system 1000 can be fully mobile and / or portable. In some embodiments, the clothing shell 100 may include separate pockets for the power supply 145 and the controller 150, respectively. In some embodiments, the battery 145, the controller 150, and the light panel 110 may all be housed in the same pocket.

[0058] In some embodiments, power source 145 is operatively connected to light panel 110 and configured to provide power to light panel 110. In some embodiments, power source 145 may be any suitable power source, such as a portable battery, a rechargeable battery, or a power cord connected to a wall outlet. In some embodiments, power source 145 may be a portable and rechargeable battery. Power source 145 may be lightweight and small in size, allowing it to be comfortably housed in clothing housing 100 and not interfere with patient 102 when worn. In some embodiments, power source 145 may be configured to provide continuous power to phototherapy system 1000. In some embodiments, power source 145 may be a battery connectable to a power cord and a wall outlet, configured to provide continuous power to phototherapy system 1000 when connected to a wall outlet. In some embodiments, power source 145 may be a battery connectable to a power cord and a wall outlet, capable of supplying power to phototherapy system 1000 when not connected to a wall outlet. In some embodiments, power source 145 may be a rechargeable battery, which provides approximately 1 hour to approximately 3 hours of power when fully charged. In some embodiments, the power supply 145 can provide approximately three times the average breastfeeding time of an infant.

[0059] Sensor 140 may be configured to monitor at least one biosignal of patient 102 and / or signals related to the internal environment of clothing 100. For example, sensor 140 may be configured to monitor at least one of the following: the position of clothing 100, the temperature inside clothing 100, the temperature of light panel 110, the humidity inside clothing, and / or the bilirubin level of patient 102. Sensor 140 may include at least one of the following: a temperature sensor, a humidity sensor, a humidity detector, a light intensity sensor, a global positioning system (GPS) sensor, a sound detector, a motion detector, an accelerometer, and / or a bilirubin detector. In some embodiments, the signals acquired by sensor 140 may serve as safety parameters to facilitate the safe operation of phototherapy system 100 when treating infants. In some embodiments, sensor 140 may be integrated into light panel 110. In some embodiments, sensor 140 may be integrated into clothing 100 (e.g., sewn into a portion of clothing 100). In some embodiments, sensor 140 may be integrated into a circuit board (e.g., FCB 216) of light panel 110. In some embodiments, sensor 140 may be configured to be in contact with the skin of patient 102. In some embodiments, sensor 140 may transmit acquired data to controller 150 for analysis, storage, and / or transmission to external device 180. In some embodiments, the sensor may be configured to continuously monitor signals. In some embodiments, the sensor may be configured to periodically monitor signals and / or monitor at predetermined time intervals.

[0060] In some embodiments, controller 150 is operatively connected to light panel 110, power supply 145, sensor 140, and / or external device 180. Controller 150 is configured to receive information related to a phototherapy session. For example, controller 150 may receive information from external device 180, sensor 140, and / or directly from light panel 110. This information may include, but is not limited to: patient 102's biosignals (e.g., bilirubin levels acquired by sensor 140), patient 102's medical history, user input (e.g., from external device 180), output parameters of the light panel, duration of light panel activation, and / or phototherapy prescription (e.g., light duration and intensity). Controller 150 is configured to adjust the output of light panel 110 based on the received information. In some embodiments, controller 150 may adjust the irradiance of the light source by changing the current supplied to light panel 110. In some embodiments, the information monitored by controller 150 may correspond to one or more safety parameters for safely providing phototherapy to an infant. In some embodiments, controller 150 may be configured to detect whether one or more safety parameters exceed a predetermined threshold and / or exceed a predetermined range. In some embodiments, the safety parameters may have a predetermined range. If the measured signal exceeds this range, the controller 150 may adjust the output of the light panel 110 and / or issue an alarm to the user via an external device 180 (e.g., using sound, text message, flash, buzzer, command, dialog box, etc.). In some embodiments, the controller 150 may cause the external device 180 to display a message notifying the user that the light panel 110 has been automatically turned off and / or the light source intensity has been reduced. In some embodiments, the controller 150 may issue an alarm and / or display a message to the user when the light panel 110 is automatically turned on according to parameters set by the user (e.g., on the external device 180). In some embodiments, the controller 150 may automatically turn off the light panel 110 according to the treatment cycle entered by the user in the user interface (e.g., on the external device 180). In some embodiments, the user may also configure the phototherapy system 1000 to only send alarms and display messages so that the user can manually turn the light panel 110 on and / or off. In some embodiments, the controller 150 may be configured to cause the external device 180 to issue an alarm to the user when the power of the phototherapy system 1000 is low.

[0061] In some embodiments, the minimum threshold of light intensity of the light source 112 on the skin surface of the patient 102 may be at least about 15 µW / cm² / nm (microwatts per square centimeter per nanometer), or at least about 30 µW / cm² / nm. In some embodiments, the predetermined upper limit threshold of the internal temperature of the garment 100 is about 40 degrees Celsius (°C). In some embodiments, the predetermined upper limit threshold of the temperature emitted by the light panel 110 is about between 38°C and 40°C. In some embodiments, the predetermined range of the internal humidity level of the garment 100 is about between 10% and 90%, including this range and all subranges. In some embodiments, the duration of a phototherapy session may be between about 5 minutes and about 24 hours, including this range and all subranges. In some embodiments, the duration of a phototherapy session may be between about 45 minutes and about 3 hours, including this range and all subranges. In some embodiments, the duration of a phototherapy session may correspond to the time of normal infant feeding, allowing the phototherapy session to be completed during feeding. In some embodiments, the duration of a phototherapy session may depend on user input and / or prescription.

[0062] In some embodiments, controller 150 may be configured to receive information related to a phototherapy session (e.g., session duration, light intensity and / or wavelength, one or more safety parameter ranges, etc.) from an external device 180. Controller 150 may be configured to send a signal to light panel 110, causing light panel 110 to emit light according to the information related to the phototherapy session. In some embodiments, controller 150 may be configured to monitor one or more signals via sensor 140, including at least biosignals of patient 102 or signals related to the internal environment of clothing 100. In some embodiments, controller 150 may be configured to determine or detect whether one or more signals exceed a predetermined threshold and / or exceed a predetermined range. Controller 150 may be configured to adjust the output of light panel 110 when at least one signal exceeds a predetermined threshold and / or exceeds a predetermined range. For example, controller 150 may reduce the light intensity output of light panel 110 below a certain value when a signal is detected to exceed a predetermined threshold. In some embodiments, the controller 150 and / or the circuit board connected to the illumination panel 110 may include circuitry to power the illumination panel 110 according to one or more illumination panel parameters (e.g., constant voltage and / or high voltage pulses, frequency and / or duty cycle) to generate the desired light output.

[0063] The controller 150 may include one or more processors configured to perform functions, processes, and / or modules of the phototherapy system 1000. The processors of the controller 150 may be any suitable processing device configured to run and / or execute a set of instructions or code. For example, the processor may include one or more data processors, image processors, physical processing units, digital signal processors (DSPs), analog signal processors, mixed signal processors, machine learning processors, finite state machines (FSMs), compression processors (e.g., for data compression to reduce data rates and / or memory requirements), encryption processors (e.g., for secure wireless data and / or power transmission), etc. The processor may be a general-purpose processor, a central processing unit (CPU), a microprocessor, a microcontroller, a field-programmable gate array (FPGA), an application-specific integrated circuit (ASIC), a processor board, a virtual processor, etc. The processor may be configured to run and / or execute or implement software application processes and other modules, processes, and / or functions related to controlling the output of the illumination panel 110 and / or monitoring the biosignals of the patient 102. The underlying device technology can employ a variety of component types, such as metal-oxide-semiconductor field-effect transistor (MOSFET) technology, such as complementary metal-oxide-semiconductor (CMOS), bipolar technology, such as generative adversarial networks (GAN), polymer technology (such as silicon conjugated polymers and metal conjugated polymer-metal structures), and analog-digital hybrid technology.

[0064] In some embodiments, controller 150 may be connected to memory 154 for storing information (e.g., information related to a phototherapy session, such as session duration, biosignals, and / or environmental information of the phototherapy system 1000). Alternatively or additionally, controller 150 may be configured to send all information to external device 180 for storage. In other words, controller 150 may not store information locally. Memory 154 may be any suitable storage device configured to store data, information, computer code, or instructions (e.g., instructions described herein), etc. Memory may store: (1) phototherapy session information, such as duration, intensity, patient identification information, etc.; (2) data acquired from sensors; and (3) and / or other information related to the operation of system 1000. In some embodiments, memory may be and / or include one or more of the following: random access memory (RAM), static RAM (SRAM), dynamic RAM (DRAM), memory buffer, erasable programmable read-only memory (EPROM), electrically erasable read-only memory (EEPROM), read-only memory (ROM), flash memory, volatile memory, non-volatile memory, combinations thereof, etc. In some embodiments, the memory may also be configured to temporarily store sensor data, for example, until the data is transmitted to an external device 180.

[0065] In some embodiments, controller 150 may be configured to send information related to light panel 110, power supply 145, and / or sensor 140 to external device 180. In some embodiments, at least one of controller 150 and external device 180 may be configured to process and / or analyze data, such as biosignal data, location data, temperature data, and / or humidity data. In some embodiments, controller 150 may process and / or analyze data in real-time or near real-time and control light panel 110 based on the processed and / or analyzed data. For example, controller 150 may receive sensor data including raw signals related to the bilirubin level of patient 102 and may be configured to process and / or analyze the raw signals to determine the bilirubin level of patient 102. Subsequently, processor 150 may reduce and / or increase the light output intensity of light panel 110 based on the bilirubin level. In some embodiments, processor 150 may automatically or without user input turn off and / or stop the light output of light panel based on at least one of the following: sensor data (e.g., bilirubin level), user input, and / or phototherapy prescription. In some embodiments, the external device 180 may be configured to at least partially process and / or analyze the data from the sensor 140 and send the processed data to the controller 150 to control the illumination panel 110.

[0066] In some embodiments, controller 150 and / or power supply 145 may include a display configured to show information to a user. In some embodiments, controller 150 and / or power supply 145 may include one or more input / output (I / O) devices configured to directly receive input from a user.

[0067] External device 180 may include any suitable computing device, such as one or more user devices, physician devices, servers, and / or databases. External device 180 may include a mobile phone, tablet, laptop, desktop computer, or any other suitable computing device. In some embodiments, external device 180 may include a user interface configured to display information related to a phototherapy session to a user and / or receive user input to control the light panel 110. In some embodiments, external device 180 may include a display that enables controller 150 to display information related to phototherapy and / or the patient. For example, controller 150 may be configured to send information related to the light intensity and / or wavelength output by the light panel 110, causing the display to show this information to the user. In some embodiments, external device 180 may be configured to run applications on a touchscreen, remotely run websites, and / or perform remote procedure call services. In some embodiments, external device 180 (e.g., via a user interface) may be configured to display monitoring information, issue alerts to the user, and receive user instructions to control the operating status of the light panel 110 and set light panel parameters.

[0068] In some embodiments, a user can connect to the phototherapy system 1000 locally and / or remotely. For example, the controller 150 and external device 180 may be configured for remote communication. For example, the phototherapy system 1000 may include a communication interface 152 configured to communicate wirelessly (e.g., via Bluetooth, Wi-Fi, cellular networks such as 3G, 4G, 5G, 802.11X, Zigbee, etc.). In some embodiments, the communication interface 152 may include one or more satellite, Wi-Fi, Bluetooth, or cellular antennas. In some embodiments, the communication interface 152 may include one or more transmitters, receivers, and / or bidirectional transmission channels. The transmitter and receiver can exchange data via the bidirectional transmission channel. In some embodiments, the transmitter can be a receiver, and the receiver can be a transmitter. In some embodiments, the transmitter and receiver can be any device connected via the transmission channel, including the light panel 110, controller 150, external device 180, and / or data server or other medical devices. In some embodiments, the communication interface 152 may be modularly designed for easy expansion of new functionalities. The communication interface 152 may be integrated into the controller 150 and / or exist as a separate hardware component. In some embodiments, the communication interface 152 may transmit some or all of the information between the controller 150 and the illumination panel 110 and / or between the controller 150 and the external device 180.

[0069] Figure 2 This is a schematic block diagram of a light-illuminating panel 210 for providing illumination to the skin of a patient 202, according to embodiments of the present disclosure. In some embodiments, the light-illuminating panel 210 may include a plurality of light sources 212 (e.g., LEDs, OLEDs, optical fibers) connected to a circuit board (e.g., a flexible circuit board (FCB)) 216. In some embodiments, the light sources 212 may be arranged in an ordered manner (e.g., a grid structure, a sawtooth structure, a repeating pattern, etc.). In some embodiments, the light sources 212 (e.g., when placed in a clothing pocket) may be configured to be close to and emit light onto the skin surface of the patient 202. In some embodiments, the light sources 212 (e.g., LEDs) may have a viewing angle and / or be spaced apart from each other such that the intensity of the light emitted by the light sources 212 on the skin surface of the patient 202 is higher than a predetermined threshold. In some embodiments, the light sources 212 may be spaced apart from each other such that there are no illumination gaps on the side of the protective housing 220 close to the patient 202 and / or on the skin surface of the patient 202. For example, the light sources 212 may be LEDs, and the spacing between these LEDs is configured such that the light projected by each LED at a predetermined distance overlaps or extends with the light projected by the adjacent LED. In the case of LEDs with a predetermined viewing angle, the spacing between the LEDs can be set according to the viewing angle and the predetermined distance to the target surface. In some embodiments, the viewing angle and the spacing between the light source 212 can be configured to make the light intensity substantially uniformly distributed on the skin surface of the patient 202.

[0070] In some embodiments, the illumination panel 210 may include approximately 10 to approximately 2000 light sources, including the range and all its sub-ranges. In some embodiments, the viewing angle of each light source 212 may be between approximately 0 degrees and approximately 180 degrees, including the range and all its sub-ranges. In some embodiments, the viewing angle of each light source 212 may be between approximately 60 degrees and approximately 130 degrees, including the range and all its sub-ranges. In some embodiments, a larger viewing angle may be desirable because each light source can project light onto a larger area, thereby reducing the number of light sources required to cover a larger surface area. In some embodiments, the distance between adjacent light sources 212 may be between approximately 2 mm and approximately 20 mm, including the range and all its sub-ranges. As described above, in some embodiments, this distance may be set according to the viewing angle of the light source 210 and / or a predetermined distance from which light is projected onto the target surface. Furthermore, as described below, the light source 210 may be housed within a protective housing 220. When housed within the protective housing 220, the housing allows light transmission, enabling the light projected by the light source 210 to reach the target surface (e.g., a baby's skin). Furthermore, to ensure even light distribution on the baby's skin, ideally, light source 210 should collectively project light through the thickness of protective shell 220 to every point on the outer surface or edge of protective shell 220. The light projected outward from the edge of protective shell 220 can then be configured to provide a uniform light distribution. Further details regarding this arrangement will be provided later. Figure 7 As described in the text.

[0071] Multiple light sources 212 and / or FCB 216 may be disposed within the protective housing 220. In some embodiments, the protective housing 220 may include one or more portions or layers. In some embodiments, the protective housing may include a single or multiple protective layers for covering the light sources 212 on the panel to protect the light sources 212 from fire and liquids such as urine, food, and feces. In some embodiments, the protective housing 220 may be waterproof or liquid-resistant. In some embodiments, the protective housing 220 may include a first portion or layer disposed on a first side (e.g., the emitting side) of the light source 212 and / or the first side of the FCB 216. The first portion or layer of the protective housing 220 may protect the light source 212 from damage (e.g., liquids such as sweat or urine, or physical damage caused by applied force). In some embodiments, the protective housing 220 may include a second portion or layer disposed on a second side (e.g., the non-emitting side) of the light source 212 and / or the second side of the FCB 216, such that the protective housing 220 covers the light sources 212 and / or the FCB 216. In some embodiments, the first portion may be connected to the second portion (e.g., sealed, fixed) to form a protective shell, thereby protecting the internal environment of the shell from external environmental influences. In some embodiments, the protective shell 220 may serve as a light guide, directing light from the light source 212 to the skin of the patient 202. In some embodiments, the protective layer 220 may reduce stray light, for example, by having surfaces that block light from deviating from the target area or reflect light back to the target area.

[0072] The protective shell 220 may include a transparent material to allow light to pass through and illuminate the patient 202. In some embodiments, at least a portion of the protective shell 220 covering the light source 212 (e.g., the side facing the patient 202) may be made of a transparent material. In some embodiments, the protective shell 220 may be flexible to at least partially conform to clothing and / or the patient's body. In some embodiments, the protective shell 220 may include any suitable material, such as silicone, polyvinyl chloride (PVC), high-grade medical transparent silicone, or suitable combinations thereof. In some embodiments, the protective shell 220 material may have an IP65 protection rating. The material of the protective shell 220 may be a medical-grade material. In some embodiments, the protective shell 220 may include materials compatible with standard cleaning and disinfecting solutions.

[0073] In some embodiments, the protective shell 220 may include a light-reflecting layer 218 disposed on the second side of the light source 212 and / or the second side of the FCB 216 to reflect stray light from the plurality of light sources 212 back to the patient's skin surface. In some embodiments, the protective shell 220 may include a light-absorbing layer 218 disposed on the second side of the FCB 216 to absorb stray light from the plurality of light sources 212. In some embodiments, the light-absorbing layer may include an opaque material that absorbs light. In some embodiments, the light-absorbing layer may include a dark-colored material (e.g., dark blue, black, etc.). In some embodiments, the light-reflecting layer may include a reflective material (e.g., silver / chromium).

[0074] In some embodiments, the protective shell 220 may include a plurality of openings 222 (e.g., grooves, gaps, openings, through holes, pockets, etc.). For example, the protective shell 220 may form a plurality of openings 222 between at least partially adjacent light sources among a plurality of light sources 212. In some embodiments, a first layer of the protective shell 220 may form a first portion of the opening 222, and a second layer may form a second portion of the opening 222. In some embodiments, when the first layer and the second layer are connected, the first portion and the second portion may be aligned to form an internal space. In some embodiments, only the first layer and / or only the second layer may form the opening 222. In some embodiments, the opening 222 may be a through hole (e.g., a material gap) extending from a first surface of the protective shell 220 to a second surface, giving the protective shell 220 a perforated or mesh structure. In some embodiments, the protective shell 220 may include a plurality of grooves. In some embodiments, the opening 222 may be located in one or more layers of the protective shell 220.

[0075] In some embodiments, the opening 222 may include any suitable shape, such as circular, elliptical, square, rectangular, rhomboid, polygonal, irregular shape, etc. In some embodiments, the groove may be formed in an elliptical shape (e.g., an ellipsoid or a semi-ellipsoid).

[0076] In some embodiments, the total thickness of the protective shell 220 can range from about 2 mm to about 10 mm, including all sub-ranges within this range. In some embodiments, the total thickness of each opening 222 can range from about 0.5 mm to about 9.5 mm, including all sub-ranges within this range. In some embodiments, the opening 222 can define an internal space with a volume ranging from about 0.5 mm³ to about 5 cm³, including all sub-ranges within this range. In some embodiments, the maximum cross-sectional area of ​​the opening 222 can range from about 0.5 mm² to about 15 cm², including all sub-ranges within this range. In some embodiments, the total weight of the protective shell 220 with the opening 222 can range from about 0.1 g to about 1 kg, including all sub-ranges within this range. In some embodiments, the opening 222 can reduce the total weight of the protective shell 220 by about 50%, about 60%, about 70%, about 80%, about 90%, or about 95%. In some embodiments, the opening 222 can reduce the total weight of the protective shell 220 by about 95%. In some embodiments, the opening 222 can reduce the total weight of the light-emitting panel 210 by about X%. The reduced weight of the light panel 210 can reduce the pressure or force exerted by the light panel 210 on the baby's chest.

[0077] In some embodiments, the opening 222 may be disposed above the light source 212, allowing light to pass through it. In some embodiments, the opening 222 may be disposed between, adjacent to, and / or above the light sources 212, such that the opening 222 is located outside the light cone defined by the viewing angle of the light source 212 and / or outside other optical paths of the light source. Alternatively, the opening 222 may interfere with the optical path of the light source 212, thereby altering the light distribution emitted by each light source 212. In some embodiments, the opening 222 may function as a converging lens. In some embodiments, the internal space of the opening 222 may have a different refractive index than the protective shell material, causing light to change its angle as it passes through the opening 222. In some embodiments, the opening 222 (e.g., a groove) may be completely contained within the protective shell 220, i.e., the outer surface of the protective shell 220 remains smooth.

[0078] In some embodiments, the illumination panel 210 may be configured to emit light with an intensity ranging from about 0 µW / cm² / nm to about 100 µW / cm² / nm, including all sub-ranges within this range. In some embodiments, the illumination panel 210 may emit light of at least 30 µW / cm² / nm over the entire surface area of ​​the illumination panel 210. In some embodiments, the wavelength of the light emitted by the illumination panel 210 may be in the range of about 450 nm to about 500 nm, including all sub-ranges within this range. In some embodiments, the wavelength of the light emitted by the illumination panel 210 may be in the range of about 465 nm to about 475 nm, including all sub-ranges within this range. In some embodiments, the surface area (e.g., the area of ​​a patient) irradiated by the light panel 210 can be approximately 10 cm², 50 cm², 100 cm², 200 cm², 300 cm², 400 cm², 500 cm², 600 cm², 700 cm², 800 cm², 900 cm², 1000 cm², 1100 cm², 1200 cm², 1300 cm², 1400 cm², 1500 cm², 1600 cm², 1700 cm², 1800 cm², or 1900 cm². In some embodiments, the surface area can reach 1300 cm². In some embodiments, the light panel 210 can be configured to operate using a power of approximately 5 mW to approximately 100 mW. In some embodiments, the light panel 210 can be configured to operate using a power of approximately 50 mW to approximately 100 mW. In some embodiments, the lifespan of the light-emitting panel 210 can be from about 10,000 hours to about 100,000 hours.

[0079] In some embodiments, the illumination panel 210 can have any suitable structural configuration. For example, the illumination panel 210 can include a fiber optic light source panel made monolithically or assembled from multiple components to distribute light. In some embodiments, the fiber optic light source panel can be a flexible braided fiber optic light source panel. In such embodiments, the fiber optic panel can include a single layer or multiple layers, and can be assembled monolithically or from multiple components to distribute light. In some embodiments, the illumination panel 210 can include multiple LEDs coupled to a flexible fiber optic panel (FFP) to generate light with a predetermined wavelength and intensity and distribute the light over a large surface area (e.g., greater than 1000 cm²). In some embodiments, the LEDs can serve as the light source for the optical fiber, which is coupled to the LEDs. In some embodiments, the optical fiber can be housed within a plastic housing. In some embodiments, the LED light source can be located outside the housing. In some embodiments, the LEDs can be configured to generate light in opposite directions on opposite sides of the optical fiber segment to increase light intensity. In some embodiments, the illumination panel 210 can include multiple pixels assembled from multiple LEDs. In some embodiments, the LEDs can be positioned to form a shape and integrated monolithically with the fiber optic panel, or without the fiber optic panel. In some embodiments, the illumination panel 210 may include a plurality of OLEDs and / or a plurality of pixels assembled from the plurality of OLEDs, in any shape. The illumination panel 210 may be integrated with a fiber optic panel as a monolith, or may not include a fiber optic panel. In some embodiments, the illumination panel 210 may include multiple portions coupled to each other to generate light with a predetermined wavelength and intensity, and to distribute the light over a large surface area. In some embodiments, the illumination panel 210 may be configured to include a flexible array, a grid, a sheet, or discrete devices. The illumination panel 210 may be structurally and / or functionally similar to the illumination panel 110; therefore, Figure 2 Some details of the lighting panel 210 are not described in the text.

[0080] Figure 3A schematic block diagram of a garment housing 300 is shown, configured to receive a light-emitting panel 310 to provide light therapy to an infant wearing the garment housing, according to some embodiments. In some embodiments, the garment housing 300 may include a first fastener (e.g., a zipper) extending along the front side of the garment housing 300. The first fastener may be configured to be operable (e.g., pull, unfasten, release, etc.) to open the garment housing 300 to allow the infant to be placed inside the garment housing 300. In some embodiments, the garment housing 300 may include any suitable material, such as cotton, wool, polyester, linen, etc. In some embodiments, the garment housing 300 may include cotton. In some embodiments, at least a portion of the fabric of the garment housing 300 may be a double-layered structure (e.g., more effective at preventing light leakage through the fabric than a single layer). In some embodiments, at least a portion of the garment housing 300 may include double-layered cotton. In some embodiments, the garment housing 300 may be configured in a single size, or may be available in different sizes to fit infants of various body types and / or ages. In some embodiments, the garment housing 300 may be a swaddle. The garment shell 300, the light-emitting panel 310, and the breathable portion 330 may be structurally and / or functionally similar to the garment shell 100, the light-emitting panels 110 and 210, and / or the breathable portion 130. Figure 3 Some details of the garment casing 300 are not described in the text.

[0081] As shown, the garment housing 300 may include a first pocket (e.g., pocket 1) 304, which is disposed on or sewn to the inner surface of the garment housing 300. The first pocket may define a space in which a light-emitting panel is configured to be removably placed. In some embodiments, the space of the first pocket may extend from the back of the garment housing 300 to the front of the garment housing 300. In some embodiments, the space may be configured to allow the light-emitting panel to cover a portion of the back and / or front of the infant. In some embodiments, a first portion of the light-emitting panel 310 may cover a portion of the infant's back, and a second portion of the light-emitting panel 310 may cover a portion of the infant's chest. In some embodiments, the first pocket 304 may include a transparent material that allows light from the light-emitting panel 310 to pass through the transparent material and illuminate the infant. In some embodiments, the first pocket 304 may include a mesh material. In some embodiments, the first pocket 304 may include a fabric, such as polyester. In some embodiments, the first pocket 304 may include a second fastener (e.g., a zipper). In some embodiments, the second fastener may be operable from the front and / or back of the garment 300. In some embodiments, the second fastener may be operable from the back of the garment 300. In some embodiments, the second fastener may be configured to be openable (e.g., pull-open) so that the illumination panel 310 can be placed within the space.

[0082] In some embodiments, the garment housing 300 may include a second pocket (e.g., pocket 2) 305 that defines a space configured to accommodate one or more additional components of the phototherapy system. For example, the second pocket 305 may be configured to accommodate a controller 350, a power supply 345, and / or at least a portion of a sensor 340. In some embodiments, the second pocket 305 may include a third fastener (e.g., a zipper) configured to open and close the second pocket 305. In some embodiments, the second pocket 305 may be located on the back side of the garment housing 300 and / or near the bottom of the garment housing 300.

[0083] In some embodiments, the garment housing 300 may further include a breathable portion 330 (e.g., a mesh structure, lace, breathable fabric, one or more openings defined in the fabric, etc.) disposed on at least a portion of the garment housing 300. The breathable portion 330 may allow light or heat emitted from the light-emitting panel to dissipate from the garment housing 300. In some embodiments, when an infant is placed inside the garment housing 300, the breathable portion 330 may be at least partially aligned with the infant's abdomen and / or lower body. In some embodiments, the breathable portion 330 may be configured to align with at least a portion of the light-emitting panel 310 when the light-emitting panel 310 is placed inside the garment housing 300. In some embodiments, the garment housing 300 may include an active heat dissipation mechanism (e.g., a fan, blower, cooling material, etc.).

[0084] In some embodiments, the garment housing 300 may further include a protective flap 332. The protective flap 332 may be configured to selectively cover the breathable portion 330. For example, the protective flap 332 may be movable between a first state and a second state, in which the protective flap 332 does not cover the breathable portion 330, and in a second state, the protective flap 332 covers the breathable portion 330. In some embodiments, the protective flap 332 may be movable between the first and second states by a user (e.g., a mother). In some embodiments, the protective flap 332 may be attached to and / or sewn to one side of the garment housing 300, allowing the protective flap 332 to move over the breathable portion 330. In some embodiments, the protective flap 332 may prevent light leakage from the garment housing 300. In some embodiments, the protective flap 332 may prevent light from shining towards the user holding the baby. In some embodiments, the protective flap 332 may include a material such as cotton (e.g., double-layered cotton). In some embodiments, the garment housing 300 may include a body, the breathable portion 330, and the protective flap 332. The main body and protective flap 332 may include a first material, and the breathable portion 330 may include a second material different from the first material. In some embodiments, the first material may include cotton (e.g., double-layered cotton), and the second material may include polyester (e.g., mesh polyester). In some embodiments, the main body of the garment shell 300 may define a first space in which the baby is placed, and a first pocket 304 may define a second space separate from the first space in which a light-emitting panel is placed.

[0085] In some embodiments, the garment housing 300 may further include a pair of armholes 306. The pair of armholes may define adjustable-sized openings. For example, each armhole 306 may include a zipper configured to open and / or tighten the armhole 306. In some embodiments, the armholes 306 may be configured to fit snugly against the infant's arm to prevent light leakage from the garment housing 300. For example, the outer edge of each armhole 306 may be configured to fit snugly against the infant's arm to prevent light leakage through the armhole 306. In some embodiments, the garment housing 300 may further include a neck opening 308 through which the infant's head can be inserted. In some embodiments, the neck opening 308 may be connected to a light-shielding collar (hereinafter referred to as the "collar") 311, which is configured to prevent light leakage from the garment housing 300 through the neck opening 308. In some embodiments, the collar 311 may protect the infant's eyes and / or brain from light exposure. In some embodiments, the collar 311 may allow the infant to be without goggles during phototherapy. In some embodiments, the neckband may include adjustable components such as drawstrings, Velcro (VELCRO®), elastic bands, etc., to seal light within the garment housing 300.

[0086] Figure 4A phototherapy system is shown, comprising a garment housing 400 worn by an infant 402 and configured to house a light-emitting panel for providing phototherapy to the infant 402, according to some embodiments. As shown, the garment housing 400 may be a swaddle including a closed bottom. The garment housing 400 may include a pair of armholes 406 through which the infant 402's arm can be inserted. Each armhole 406 includes an adjustable portion (e.g., a zipper, drawstring, Velcro (VELCRO®), etc.) to allow the armhole 406 to be adjusted to fit snugly against the infant's arm and to prevent light leakage from the garment housing 400 through the armhole 406. As shown, each armhole 406 may be pulled along its length to decrease and / or increase the diameter of the opening defined by the armhole 406. The garment housing 400 may further include a neck opening 408 through which the infant 402's head can be inserted. The neck opening 408 is connected to the collar 411, which includes an adjustable portion to allow the collar 411 to be adjusted to prevent light from leaking from the garment housing 400 and shining on the baby's face.

[0087] The garment housing 400 includes a first fastener 403 (e.g., a zipper) extending along the length of the garment housing 400 and configured to open the garment housing 400 to allow placement of the infant 402 therein. In some embodiments, the first fastener 403 may be located on the front side of the garment housing 400. In some embodiments, the first fastener 403 may be located on the back side of the garment housing 400. The garment housing 400 may also include a second fastener 407 (e.g., a zipper) extending at least partially along the torso of the infant 402. The second fastener 407 may be connected to a first pocket (not shown) disposed inside the garment housing 400. The second fastener 407 may be configured to open the first pocket, allowing a user to access the pocket and place a light therapy panel therein.

[0088] As shown in the figure, the garment housing 400 further includes a ventilated portion 430 configured to allow light and / or heat to escape from the garment housing 400 and / or allow cool air to enter the garment housing 400. The ventilated portion 430 may cover the lower half of the front side of the infant 402. The garment housing 400 may include a protective flap 432 configured to move to cover at least a portion of the ventilated portion 430. As shown in the figure, the protective flap 432 is in an open state (e.g., a first state) and can be switched to a closed state by a user. In some embodiments, the phototherapy system and the garment housing 400 may be structurally and / or functionally similar to the phototherapy system 1000 and garment housings 100, 300; therefore, certain aspects of the garment housing 400 are not described herein.

[0089] Figures 5A-5BFront and rear views of a garment housing 500, configured to house a light-emitting panel for providing light therapy to an infant, are shown, according to some embodiments. Figure 5A As shown, the garment housing 500 includes a first fastener 503, a second fastener 507 connected to a first pocket (not shown), a breathable portion 530, a pair of armholes 506, and a neck hole connected to a collar 511. The garment housing 500 may be structurally and / or functionally similar to garment housings 100, 300, and 400; therefore, certain details of the garment housing 500 are not described herein.

[0090] The garment housing 500 may include a sensor 540, which is connected to and / or sewn therein. As shown, the sensor 540 is disposed in the chest area and / or back area of ​​the garment housing 500. Figures 5A-5B Outline 510 is shown, corresponding to the upper boundary of a light-emitting panel in the first pocket within the garment housing 500. As shown, the light-emitting panel is configured to at least cover the infant's chest.

[0091] like Figure 5B As shown, the garment housing 500 further includes a second pocket 505 disposed on the back side of the garment housing 500. The second pocket 505 includes a zipper 509 configured to open and / or close the second pocket 505. The second pocket may be configured to accommodate a controller and / or a power source 545. The power source 545 may be configured to supply power to a light panel via one or more electrical connectors 556, 558 (e.g., cables, wires, conductive traces, conductive wires, adapters, sockets, etc.). In some embodiments, one or more electrical connectors 556, 558 may be sewn into the fabric of the garment housing 500. The garment housing 500 may include a first electrical connector 556 (e.g., an adapter) configured to connect a battery 545 and / or a controller to a second electrical connector 558 (e.g., cables, wires, conductive wires, etc.).

[0092] Figure 5CA photograph of a garment housing 500 is shown, illustrating a first pocket 504 configured to detachably accommodate a light-emitting panel, according to some embodiments. As shown, the first pocket 504 includes a fabric portion 514 (e.g., transparent fabric) sewn to an inner surface of the garment housing 500 body, defining a space between the fabric portion and the inner surface of the body. In some embodiments, a first side of the garment housing 500 body and the fabric portion 514 may define a first space in which an infant is placed; a second side of the garment housing 500 body and the fabric portion 514 (opposite to the first side) may define a second space separate from the first space in which the light-emitting panel is placed. The first pocket 504 may include a fastener 507 for opening and / or closing the first pocket. As shown, the fastener 507 is user-operable from inside the garment housing 500.

[0093] Figures 6A-6B The front and back sides of a garment housing 600 are shown, respectively, which is configured to house a light-emitting panel to provide light therapy to an infant, according to some embodiments. Figure 6A As shown, the clothing housing 600 includes a first fastener 603 configured to open and / or close the clothing housing 600 to allow an infant to be placed therein. The first fastener 603 can open the body of the clothing housing 600, which defines a first space in which an infant can be placed. The clothing housing 600 further includes a ventilated portion 630 forming part of the front side of the body of the clothing housing 600. Figure 6B As shown, the garment housing 600 further includes a first pocket 604 defining a second space physically separate from the first space. In some embodiments, a light-emitting panel is configured to be removably placed within the second space defined by the first pocket 604. The first pocket 604 may include a portion formed of a transparent material, allowing light to pass through the transparent material and illuminate the first space where the infant is located. The garment housing 600 further includes a second pocket 605 defining a third space configured to accommodate one or more electrical components. For example, the second pocket 605 may be configured to accommodate at least one power source and / or controller. The second pocket 605 includes a second fastener 609 configured to open and / or close the second pocket. As shown, the second pocket 605 may be located on the lower back side of the garment housing 600. The garment housing 600 may also include a pair of armholes 606, each armhole including an adjustable portion or fastener for changing the size of the armholes 606 (e.g., a zipper). The garment housing 600 may be similar in structure and / or function to garment housings 100, 300, 400, and 500; therefore, certain details of the garment housing 600 are not described herein.

[0094] Figure 7A schematic cross-sectional side view of a lighting panel 710 is shown, which includes a plurality of light sources 712 and a protective housing 720, according to some embodiments. As shown, the light sources 712 (LEDs) may be connected to and / or disposed on a circuit board 716. A distance D may be included between the light sources 712. In some embodiments, the protective housing 720 may have a thickness T. In some embodiments, the protective housing 720 may include one or more openings 722 disposed between the light sources 712. In some embodiments, the openings 722 may be in the same plane as the light sources 712. Alternatively, the openings 722 may be located in a different plane or extend beyond the plane where the light sources 712 are located. For example, the openings 722 may extend below the position of the light source, but still outside the light cone of the light source 712. The openings 722 may be positioned so that they are not within the light cone of the light source 712. As shown, the openings 722 may be semi-elliptical (or semi-ellipsoidal), but it should be understood that the openings 722 may have any suitable shape. In some embodiments, the circuit board 716 may traverse the openings 722. Each of the light sources 712 may include a viewing angle α. In some embodiments, the distance D and the viewing angle α can be related by the following equation: tan(α / 2) = D / T. The distance D and the viewing angle α can be configured such that the total surface area of ​​the edge of the protective housing 720 is illuminated (e.g., within a light cone). In some embodiments, the distance D and the viewing angle α can be configured such that the total surface area illumination of the edge of the protective housing 720 is greater than 80%, greater than 90%, or greater than 95%. In some embodiments, the distance D can be approximately 1.5 cm to approximately 5 cm, including all sub-ranges within this range. In some embodiments, the viewing angle α can be approximately 100 degrees to 150 degrees, including all sub-ranges within this range. In some embodiments, the thickness T of the protective housing 720 can be approximately 0.5 mm to approximately 15 mm, including all sub-ranges within this range. The light source 712 shown by the dashed line can be optional because other light sources 712 in the illumination panel 720 have already illuminated the total surface of the edge of the protective housing. In some embodiments, the distance D, thickness T, and viewing angle α can be adjusted to uniformly distribute the light emitted by the illumination panel. For example, these parameters can be adjusted to make the light intensity substantially uniformly distributed within the target value range at the edge of the protective housing 720 (e.g., with an error within 1%). The illumination panel 710 can be structurally and / or functionally similar to the illumination panels 110 and 210, therefore, Figure 7 Some details of the lighting panel 710 are not described in the text.

[0095] Figure 8An exploded view of a lighting panel 810 is shown, which includes a plurality of light sources 812 and protective housings 820a, 820b, according to some embodiments. As shown, the lighting panel 810 includes a plurality of light sources 812 arranged in an ordered configuration (e.g., a grid configuration). Each light source 812 includes one or more wires and / or circuit boards 816 connecting them. In some embodiments, the protective housing may include a first layer 820a that defines a first set of recesses 822a (e.g., elliptical recesses). The light sources 812 and circuit boards 816 may be disposed on a second layer 820b of the protective housing. The second layer 820b may define a second set of recesses 822b between each light source 812. The position and / or shape of the first set of recesses 822a may correspond to the position and / or shape of the second set of recesses 822b. For example, the first set of recesses 822a may be aligned with the second set of recesses 822b such that the first and second sets of recesses form a sphere and / or ellipsoid defining an internal space containing air. In some embodiments, the groove can act as a converging lens to focus the light emitted by the light source 812, thereby increasing the irradiance of the light. Although Figure 8 The protective casing displays a first layer 820a and a second layer 820b, each layer including recesses 822a and 822b. However, it should be understood that the protective casing may include only one protective layer and / or only one protective layer including recesses. The illumination panel 810 may be structurally and / or functionally similar to illumination panels 110, 210, and 710; therefore, Figure 8 Some details of the lighting panel 810 are not described in the text.

[0096] Figures 9A-9B Different configurations of the illumination panels 910 and 1010 are shown, according to some embodiments. For example... Figure 9A As shown, the illumination panel 910 forms a grid defining a plurality of square openings. At least some intersections of the grid may include light sources 912. Each light source 912 may be electrically and / or physically connected via a connector (e.g., a strip) 916. For example, each strip 916 may include conductive traces, wires, cables, etc., configured for electrically connecting adjacent light sources 912. As shown, the illumination panel 910 is formed in a rectangular shape, but it should be understood that the illumination panel 910 can be formed in any suitable shape.

[0097] As shown in Figure 9B, the light-emitting panel 1010 forms a grid defining a plurality of square openings. At least some intersections of the grid may include light sources 1012. Each light source 1012 may be electrically and / or physically connected via a strip structure 1016. For example, each strip structure 1016 may include conductive lines, wires, cables, etc., for electrically connecting adjacent light sources 1012. As shown, the light-emitting panel 1010 forms a rectangular shape and includes a pair of protrusions. In some embodiments, the protrusions, extensions, or flanges of the light-emitting panel 1010 may be configured to wrap around from the back of the infant to the front of the infant, for example, when the light-emitting panel 1010 is disposed in clothing for phototherapy. The light-emitting panels 910 and 1010 may be structurally and / or functionally similar to the light-emitting panels 110, 210, 710, and 810, therefore certain details of the light-emitting panels 910 and 1010 are not depicted in Figures 9A-9B.

[0098] Figures 10A-10B illustrate different configurations of illumination panels 1110 and 1210 according to embodiments. As shown, illumination panel 1110 forms an interlaced grid structure, wherein light sources 1112 can be arranged in an interlaced manner. As shown, the first set of connectors 1121 can be physical connections, and the second set of connectors 1116 can include electrical connections and / or circuitry. For example, the first set of connectors 1121 can include silicone, and the second set of connectors 1116 can include silicone-coated circuitry. The second set of connectors 1116 can be used to provide data and / or power to the light sources 1112. In some embodiments, the second set of connectors 1116 can be configured to extend along a first direction (e.g., parallel to each other), while the first set of connectors 1121 can extend along a second and a third direction. For example, the first set of connectors 1121 can be arranged such that illumination panel 1110 defines a plurality of herringbone-like structures.

[0099] As shown in Figure 10B, the illumination panel 1210 forms a structure resembling an interlaced grid, in which the light sources 1212 can be arranged in an interlaced pattern. The illumination panel includes a first set of connectors 1221 (physical connectors) and a second set of connectors 1216 (including electrical connections and / or circuitry). In some embodiments, the first set of connectors 1221 can be arranged in a zigzag pattern. The zigzag structure provides stronger physical connections and can support the greater weight of the illumination panel 1210. The zigzag pattern can also increase the irradiance of the light sources because the zigzag arrangement may increase the overlap of light emission between the light sources. For LED designs, this helps to make the light distribution more uniform. Both illumination panels 1110 and 1210 can be defined with openings (in other words, they are mesh panels). The illumination panel 1210 may be structurally and / or functionally similar to illumination panels 110, 210, 710, 810, 910, and 1010, therefore some details of the illumination panel 1210 are not depicted in Figures 10A-10B.

[0100] Figure 11 illustrates a protective housing 1320 configured to couple with a light-emitting panel according to an embodiment, the protective housing 1320 including a light absorber 1318. As shown, the protective housing 1320 defines a plurality of openings 1322. The openings 1322 may extend from a first side to a second side of the protective housing 1320. As shown, the protective housing 1320 may be a mesh structure (e.g., forming a grid). The light absorber 1318 does not define openings. As shown, the light absorber 1318 is a single piece of material. The light absorber may include an opaque or dark material to absorb light. In some embodiments, a light source may be positioned at the edge of the openings 1322. In some embodiments, the light source may be positioned at the intersection of the mesh structure. In some embodiments, the light source may be positioned at the edge of the mesh structure.

[0101] Figure 12AA schematic diagram of a protective shell 1420 is shown, which includes openings 1422 disposed above light sources 1412. As shown, the openings 1422 have a circular cross-sectional shape. These openings 1422 may be located on the outer surface of the protective shell 1420, facing and protruding towards the baby's skin (e.g., protruding into the baby's skin). Therefore, this design may cause discomfort to the baby due to the protrusion towards the baby's chest. In contrast, Figure 12B shows a schematic diagram of a protective shell 1620 according to an embodiment, which includes openings 1622 disposed between adjacent light sources 1612 and located on the inner surface of the protective shell 1620. As shown, the light sources 1612 may be arranged in an ordered pattern, and the openings 1622 may be disposed therebetween. As shown, the openings 1622 may be elliptical (or have an elliptical cross-section). The openings 1622 may be contained within the protective shell 1620, such that the surface of the protective shell facing the baby's chest is flat and / or smooth. This design may be more comfortable because there are no protrusions that compress the baby's chest. Protective cases 1420 and 1620 may be structurally and / or functionally similar to any of the protective cases described herein, therefore their details are not further described in Figures 12A-12B.

[0102] Figure 13 A schematic diagram of a light-emitting panel 1700 having a shape corresponding to a pocket of a garment shell, according to an embodiment, is shown. The light-emitting panel 1710 may include multiple light sources and multiple connectors 1716 (e.g., physical and / or electrical connections) connecting these light sources. As shown, the connectors 1716 may be arranged in a zigzag pattern to enhance physical connection strength and / or support greater weight, and / or increase the irradiance of the light-emitting panel 1710. The light-emitting panel 1710 may include a central portion 1710a, and a first extension (e.g., a flange, protrusion, etc.) 1710b and a second extension 1710c extending laterally from the central portion. The central portion 1710a may be configured to align with the patient's back, while the extensions 1710b and 1710c may be configured to surround the patient and cover a portion of the patient's chest, respectively.

[0103] Figures 14A-14CAn example of a user interface 1890 (e.g., executable on an external device) for controlling a light panel of a phototherapy system according to an embodiment is shown. As shown in FIG14A, the user interface 1890 may display information related to: (1) a patient identifier (ID) 1891, a healthcare worker identifier associated with the patient 1893, a device identifier associated with the patient 1895, treatment parameters 1892a, 1892b, 1892c (including sensor data from a treatment session), and / or session log 1897. For example, the user interface 1890 may display the irradiance 1892a provided during a selected session, the upper temperature threshold 1892b, and / or the lower temperature threshold 1892c used during the selected session. The user interface 1890 may be configured to allow a user to select an icon for more information. In some embodiments, the user interface 1890 may be configured to receive user input. User input may include selection of phototherapy session parameters (e.g., duration, intensity), session-related notes, and / or input for stopping or starting power supply to the light panel.

[0104] like Figure 14B As shown, the user interface 1890 allows the user to select a date and displays a session log containing multiple session summaries 1898a, 1898b, and 1898c. Session summaries 1898a-1898c may include information related to the phototherapy session provided on that date. As shown in Figure 14C, the user interface can be configured to display a patient profile page, including, for example, a patient identifier 1891, patient-related information 1894, patient-related notes 1896, and / or a patient-associated phototherapy prescription 1895. This user interface provides infant caregivers with an easy way to manage phototherapy treatments using the phototherapy system. The user interface can allow real-time or near real-time updates to be displayed to the user, enabling the user to securely monitor the implementation of phototherapy sessions.

[0105] Figure 15 illustrates a flowchart method 1500 for performing phototherapy using a phototherapy system according to an embodiment. Although method 1500 is described herein in conjunction with phototherapy system 1000, it should be understood that method 1500 is applicable to any phototherapy system described herein. Method 1500 may include receiving information related to a phototherapy session from an external device 180 in step 1510. This information may include at least one of the following: session duration, preset light intensity, patient's bilirubin level, patient's session history, etc. In some embodiments, the controller coupled to controller 150 and / or external device 180 may be configured to receive information related to phototherapy system 1000. In some embodiments, the information related to a phototherapy session may be user input. In step 1512, the method includes sending a signal to a light panel 110 (e.g., an LED panel) to cause the light panel 110 to emit light according to the information related to the phototherapy session. For example, controller 150 may send a signal (e.g., a voltage and / or current signal) to cause the light panel 110 to emit light at a preset light intensity and / or for a preset time period. In some embodiments, a user can adjust parameters of a phototherapy session (e.g., via a user interface). In step 1514, the method includes monitoring one or more signals, including at least biological signals of the infant 102 or signals related to the environment of the clothing 100 in which the infant 102 is located. For example, the controller 150 may be configured to monitor (e.g., via sensor 140) the temperature inside the clothing 100 and / or the bilirubin level of the infant 102. The method may optionally include determining in step 1516 whether one or more signals exceed preset thresholds (e.g., maintaining the temperature below a preset threshold and / or the light intensity within a preset range). In some embodiments, the controller 150 may also be configured to receive information related to user input (e.g., from an external device) before or during a phototherapy session, and / or the controller 150 may directly receive user input.

[0106] Method 1518 may include adjusting the output of the light panel 110 when at least one of the following occurs: one or more signals exceed a preset threshold, or user input is received. In some embodiments, if one or more signals exceed the preset threshold, the method may include increasing and / or decreasing the light intensity, or turning off the light panel 110. For example, if the temperature rises above a preset threshold (e.g., 40°C), the method may include decreasing the light intensity emitted by the light panel 110 and / or turning off the light panel 110. In some embodiments, the controller 150 may automatically adjust the output. In some embodiments, the user may manually adjust the output. In some embodiments, method 1500 may optionally include issuing an alert to the user (e.g., via an external device 180) indicating that a signal has exceeded a corresponding preset threshold. Method 1500 may also include storing information related to the phototherapy session in memory (e.g., on the controller 150 and / or the external device 180). In some embodiments, the stored phototherapy session-related information may be used to guide future sessions. The method 1500 described herein allows a user to remotely monitor and / or easily perform infant phototherapy and receive real-time and / or near-real-time updates related to the phototherapy.

[0107] Various concepts can be embodied as one or more methods, of which at least one example is provided. The steps performed as part of a method can be ordered in any suitable manner. Therefore, embodiments can be constructed such that the order of execution of the steps differs from that illustrated, which may include the simultaneous execution of certain steps, even if shown as sequential execution in the exemplary embodiments. In other words, it should be understood that these features are not necessarily limited to a specific execution order, but can be executed serially, asynchronously, concurrently, in parallel, simultaneously, synchronously, etc., in a manner consistent with this disclosure by any number of threads, processes, services, servers, etc. Therefore, some of these features may contradict each other, i.e., they cannot coexist in a single embodiment. Similarly, some features may be applicable to one aspect of the innovation but not to others.

[0108] Furthermore, this disclosure may include other innovations not currently described. The applicant reserves all rights to such innovations, including the right to implement them, file supplemental applications, continuation applications, partial continuation applications, divisional applications, etc. Therefore, it should be understood that the advantages, embodiments, examples, functions, features, logic, operation, organization, structure, topology, and other aspects of this disclosure should not be considered as limitations on this disclosure, nor as limitations on the embodiments or their equivalents. Various embodiments of the technologies disclosed herein can be implemented in a highly flexible and customized manner, as described herein, depending on the specific needs and / or characteristics of individual and / or enterprise users, database configuration and / or relational models, data types, data transmission and / or network frameworks, syntax structures, etc.

[0109] All definitions used in this document should be understood to take precedence over dictionary definitions, definitions in referenced documents, and / or the general meaning of the defined terms.

[0110] In the specific embodiments used herein, the terms “about” or “approximately” appearing before a numerical value indicate that the value has a range of 10% above or below it. When a numerical range is provided, it should be understood that every intermediate value between the upper and lower limits of the range (accurate to the decimal places of the lower limit unit, unless the context explicitly specifies otherwise) and any other stated value or intermediate value within the range are included in this disclosure. Furthermore, the upper and lower limits of these smaller ranges may be independently included within the smaller range and also within this disclosure, subject to any express exclusions within the range. When the range includes one or two upper and lower limits, the range excluding one or both of those limits is also included in this disclosure.

[0111] The phrase “and / or” as used in this specification and embodiments should be understood to mean “any one or both,” meaning that these elements exist simultaneously in some cases and individually in others. Multiple elements listed using “and / or” should be interpreted in the same way, i.e., elements connected by “one or more.” In addition to the elements specifically identified in the “and / or” clause, other elements may optionally exist, whether or not they are related to the specifically identified elements. Therefore, as a non-limiting example, when used in conjunction with open-ended language such as “including,” a reference to “A and / or B” may refer only to A in one embodiment (optionally including elements other than B); in another embodiment it may refer only to B (optionally including elements other than A); in yet another embodiment it may refer to both A and B (optionally including other elements); and so on.

[0112] The term “or” as used in this specification and embodiments should be understood to have the same meaning as “and / or” above. For example, when used to separate items in a list, “or” or “and / or” should be interpreted as inclusive, meaning it includes at least one element, but may also include multiple elements, and may optionally include other unlisted items. Only terms that explicitly indicate the opposite meaning, such as “only one of” or “exactly one of”, or “consisting of” as used in embodiments, indicate that only one element in the list is included. Generally, the term “or” as used herein is interpreted as indicating an exclusive choice (i.e., “either one or the other”) only when preceded by an exclusive term (e.g., “any one,” “one of,” “only one of,” or “exactly one of”). “Substantially consisting of”, when used in embodiments, should have the usual meaning in the field of patent law.

[0113] The phrase "at least one" as used in this specification and embodiments, when referring to a list of one or more elements, should be understood to mean selecting at least one element from any one or more elements in that list, but not necessarily including at least one of every element in the list, nor excluding any combination of elements in the list. This definition also allows for the selective presence of other elements besides those specifically identified in the list referred to by "at least one," regardless of whether these elements are related to the specifically identified elements. Thus, as a non-limiting example, "at least one A and B" (or equivalent "at least one A or B," or equivalent "at least one A and / or B") in one embodiment may refer to at least one (optionally including multiple) A, without B (and may optionally include other elements besides B); in another embodiment it may refer to at least one (optionally including multiple) B, without A (and may optionally include other elements besides A); in yet another embodiment it may refer to at least one (optionally including multiple) A and at least one (optionally including multiple) B (and may optionally include other elements); and so on.

[0114] In the embodiments and the above description, all transitional phrases, such as "including," "comprising," "carrying," "having," "containing," "involving," "holding," "consisting of," etc., should be understood as open-ended, meaning "including but not limited to." Only the transitional phrases "consisting of" and "basically composed of" should be understood as closed or semi-closed transitional phrases, respectively.

[0115] While specific embodiments of the present disclosure have been outlined above, those skilled in the art will understand that many alternatives, modifications, and variations will be apparent. Therefore, the embodiments listed herein are intended for illustrative purposes and not for limitation. Various modifications may be made without departing from the spirit and scope of the present disclosure. When the methods and steps described above indicate that certain events occur in a specific order, those skilled in the art will recognize upon reading this disclosure that the order of certain steps may be modified, and such modifications conform to variations of the invention. Furthermore, certain steps may be performed in parallel where possible, or sequentially in the order described above. Although these embodiments have been specifically shown and described, it should be understood that various changes to their form and details are possible.

[0116] The order of the above embodiments is for ease of description only and does not represent the superiority or inferiority of the embodiments.

[0117] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, and not to limit them; although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some of the technical features; and these modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the spirit and scope of the technical solutions of the embodiments of the present invention.

Claims

1. An apparatus for providing phototherapy to an infant, the apparatus comprising: a garment shell configured to be openable to enable the infant to be placed inside the garment shell, the garment shell comprising: a first pocket disposed on an inner surface of the garment shell, the first pocket defining a space for removably placing a phototherapy panel, the phototherapy panel comprising a plurality of light sources configured to emit light at a predetermined wavelength and intensity, the space of the first pocket extending from a back side to a front side of the garment shell such that, when the infant is placed inside the garment shell and the phototherapy panel is placed in the first pocket, a first portion of the phototherapy panel is aligned with a back of the infant and a second portion of the phototherapy panel is aligned with a chest of the infant; a second pocket defining a space on the garment shell, the second pocket configured to house a battery and a controller in operative connection with the phototherapy panel; and a mesh structure forming a portion of the garment shell and configured to allow at least light or heat emitted by the phototherapy panel to be expelled from the garment shell through the mesh structure.

2. The apparatus of claim 1, wherein, the garment shell further comprising: a first zipper extending along the front side of the garment shell, the first zipper configured to be operable to open the garment shell to enable the infant to be placed inside the garment shell.

3. The apparatus of claim 1, wherein, the garment shell further comprising: a movable flap attached to a side of the garment shell, the movable flap having a first state in which the flap does not cover the mesh structure and a second state in which the flap covers the mesh structure to block light emitted by the phototherapy panel from being expelled through the mesh structure.

4. The apparatus of claim 3, wherein, the movable flap is movable by a user holding the infant between the first state and the second state.

5. The apparatus of claim 1, wherein, the mesh structure is at least partially aligned with an abdomen of the infant when the infant is placed inside the garment shell.

6. The apparatus of claim 1, wherein, the phototherapy panel comprises one or more sensors coupled thereto, the one or more sensors configured to monitor at least one of a biological signal of the infant or an internal environment of the garment shell.

7. The apparatus of claim 6, wherein, the biological signal of the infant can comprise a bilirubin level of the infant.

8. The apparatus of claim 5, wherein, the internal environment of the garment shell comprises at least one of a position of the garment shell, a temperature inside the garment shell, a temperature of the phototherapy panel, or a humidity inside the garment shell.

9. The apparatus of claim 1, wherein, the garment shell comprises a double layer of cotton fabric.

10. The apparatus of claim 1, wherein, a portion of the first pocket comprises a transparent material such that light emitted by the phototherapy panel is able to be shone onto the infant's skin when the infant is placed inside the garment shell.

11. The apparatus of claim 1, wherein, the garment shell further comprising: a pair of arm holes configured to be passed through by arms of the infant, each arm hole being adjustable in size such that an outer edge of each arm hole is snug against an arm of the infant to prevent light from leaking from inside the garment shell through the pair of arm holes; and a neck hole configured to be passed through by a head of the infant, wherein the neck hole comprises a light-blocking collar to prevent light from leaking from inside the garment shell through the neck hole.

12. The apparatus of claim 1, wherein, the garment shell is a swaddle.

13. The apparatus of claim 1, wherein, the plurality of light sources comprise light emitting diodes (LEDs).

14. The apparatus of claim 1, wherein, the garment shell comprises an active heat dissipation mechanism comprising a fan.

15. An apparatus comprising: a flexible circuit board; a plurality of light sources arranged in an ordered configuration, the plurality of light sources coupled to a first side of the flexible circuit board; and a second side of the flexible circuit board. a flexible protective shell coupled to the flexible circuit board and the plurality of light sources, the protective shell disposed on a second side of the plurality of light sources and a second side of the flexible circuit board, the flexible protective shell comprising a plurality of apertures disposed between at least some adjacent light sources, wherein the plurality of light sources are configured to emit light proximate to and toward a skin surface of an infant, the plurality of light sources having a field of view and being spaced apart from each other such that the intensity of light emitted by the plurality of light sources at the skin surface of the infant is above a predetermined threshold.

16. The apparatus of claim 15, wherein, The field of view of each of the plurality of light sources ranges between 0 degrees and 180 degrees.

17. The apparatus of claim 15, wherein, The protective shell comprises at least one of silicone or polyvinyl chloride (PVC).

18. The apparatus of claim 15, wherein, The protective shell comprises a first layer and a second layer coupled together, the first layer disposed on the second side of the light sources and the second layer disposed on the second side of the flexible circuit board, the first layer defining a first portion of the plurality of apertures and the second layer defining a second portion of the plurality of apertures.

19. The apparatus of claim 15, wherein, The protective shell covering the second side of the plurality of light sources is at least partially transparent.

20. The apparatus of claim 15, wherein, The protective shell further comprises a light reflecting layer disposed on the second side of the flexible circuit board such that stray light from the plurality of light sources is reflected back toward the skin surface of the infant.

21. The apparatus of claim 15, wherein, The protective shell further comprises a light absorbing layer disposed on the second side of the flexible circuit board such that stray light from the plurality of light sources is absorbed.

22. The apparatus of claim 15, wherein, The predetermined threshold of the intensity of light is at least 30 µW / cm² / nm (microWatts per square centimeter per nanometer).

23. The apparatus of claim 15, wherein, The device is configured to be disposed in a fully portable swaddle, the circuit board coupled to a controller and a battery, the controller and battery each configured to be disposed in the swaddle.

24. The apparatus of claim 15, wherein, The plurality of apertures reduces the overall weight of the protective shell.

25. The apparatus of claim 15, wherein, The ordered configuration is in a grid pattern.

26. The apparatus of claim 15, wherein, The apertures are located outside a light cone defined by the field of view of the light sources.

27. The apparatus of claim 15, wherein, The plurality of light sources comprises light emitting diodes (LEDs).

28. A system comprising: a phototherapy panel configured to be disposed in an infant garment, the phototherapy panel configured to emit light during a phototherapy process to treat a condition of an infant; one or more sensors disposed in the garment; and a controller operatively coupled to the phototherapy panel, the one or more sensors, and an external device, the controller configured to: receive information related to the phototherapy process from the external device; send a signal to the phototherapy panel to cause the phototherapy panel to emit light according to the information related to the phototherapy process; monitor one or more signals via the one or more sensors, the one or more signals comprising at least one of a biological signal of the infant or a signal related to an internal environment of the garment; determine whether the one or more signals exceed a predetermined threshold; and adjust an output of the phototherapy panel when at least one of the signals exceeds the predetermined threshold. The information related to the phototherapy process comprises at least one of a wavelength of the light, an intensity of the light, or a duration of the phototherapy process. The internal environment of the garment comprises at least one of a location of the garment, a temperature inside the garment, a temperature of the phototherapy panel, or a humidity inside the garment.

29. The system of claim 28, wherein, The controller is configured to automatically turn off the phototherapy panel when at least one of the temperature inside the garment or the temperature of the phototherapy panel exceeds a predetermined threshold.

30. The system of claim 28, wherein, ​ 31. The system of claim 28, wherein, ​ 32. The system of claim 28, wherein, The disease is jaundice, and the biological signal of the infant includes a bilirubin level.

33. The system of claim 32, wherein, The controller is configured to adjust an intensity of light emitted by the phototherapy panel according to the bilirubin level.

34. The system of claim 28, wherein, The one or more signals include an amount of time the phototherapy panel has emitted light.

35. The system of claim 28, wherein, The controller is further configured to send information related to the completed phototherapy session to an external device for storage.

36. The system of claim 28, wherein, The external device is configured to receive user input corresponding to the phototherapy session related information.

37. The system of claim 28, wherein, The garment is a swaddle.

38. The system of claim 28, wherein, The phototherapy panel includes an LED panel.

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