An image generation method, an image acquisition method and related devices
By calculating the substance and molar concentration of gadolinium contrast agent in combination with patient weight, injecting saline and gadolinium contrast agent, and monitoring the concentration in the coronary arteries to generate CT data, the problem of poor filling effect caused by the subjectivity of gadolinium contrast agent dosage is solved, thus improving image quality and safety.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- CHINESE ACADEMY OF MEDICAL SCIENCES FUWAI HOSPITAL SHENZHEN HOSPITAL (SHENZHEN SUN YAT-SEN CARDIOVASCULAR HOSPITAL)
- Filing Date
- 2026-03-30
- Publication Date
- 2026-06-26
AI Technical Summary
In existing coronary CT angiography techniques, the dosage of gadolinium contrast agent is determined based on subjective experience, resulting in poor filling effect of gadolinium contrast agent in the coronary arteries and reduced image quality.
The target dose is calculated by obtaining the substance and molar concentration of a specified gadolinium contrast agent, combined with the patient's weight, and then injecting saline and gadolinium contrast agent into the syringe assembly. The concentration in the coronary artery is monitored, and CT data is generated using the scanning assembly to produce the target image.
Objectively calculate the target dose of gadolinium contrast agent to ensure adequate filling of the coronary arteries, improve image quality, and ensure patient safety.
Smart Images

Figure CN122272056A_ABST
Abstract
Description
Technical Field
[0001] This application relates to the field of imaging, and more particularly to an image generation method, an image acquisition method, and related apparatus.
[0002] Coronary atherosclerotic heart disease (CAD) has become the second leading cause of cardiovascular disease death in my country, primarily due to insufficient myocardial blood supply caused by coronary artery stenosis. CAD has at least three characteristics: First, it has a high incidence rate and a large population base. Risk factors such as hypertension, hyperlipidemia, diabetes, smoking, obesity, and aging are prevalent, making CAD a highly prevalent disease among middle-aged and elderly people, and showing a trend towards affecting younger individuals. Second, it is extremely insidious, with no typical symptoms in the early stages. Most patients with mild to moderate coronary artery stenosis do not experience chest tightness or chest pain, only suffering acute myocardial infarction, malignant arrhythmias, or sudden cardiac death during strenuous exercise or plaque rupture. The pre-hospital mortality rate is extremely high, and there is a significant gap in early screening. Third, the lesions are complex. Coronary artery lesions include various types such as calcified plaques, non-calcified plaques, mixed plaques, vascular stenosis, myocardial bridging, and aortic dissection. Treatment plans (medications, stent implantation, coronary artery bypass grafting) are completely different for different lesions, and individualized treatment plans cannot be developed without accurate imaging. To understand the condition of coronary artery disease, coronary angiography, the "gold standard" of invasive interventional techniques, has been used. However, its high cost and risk of complications make it unsuitable for large-scale asymptomatic populations. To address these limitations, coronary CT angiography is used to assess the coronary arteries in large asymptomatic individuals. Coronary CT angiography involves intravenous injection of contrast agents combined with CT scans to non-invasively reconstruct the anatomy of the coronary arteries. As a non-invasive technique, it can be used for rapid assessment of the coronary artery condition in high-risk asymptomatic individuals (those with hypertension, hyperlipidemia, smoking, family history, etc.). It clearly displays key information such as the origin and course of the coronary arteries, the degree of stenosis, plaque characteristics, plaque burden, myocardial bridging, and vascular dissection. It requires no hospitalization, involves no interventional trauma, and reduces complications such as puncture bleeding, contrast agent nephropathy, and radiation exposure, while also lowering medical costs and conserving medical resources.
[0003] In most cases, iodine-based contrast agents are used in coronary CT angiography. Iodine, a component of iodine-based contrast agents, has a high atomic number and strong X-ray attenuation ability, resulting in high-density, high-brightness imaging of blood vessels or tissues under CT. After intravenous injection, it rapidly distributes throughout the extracellular fluid without entering cells. Under normal circumstances, it does not cross the blood-brain barrier and undergoes almost no biological metabolism, primarily being excreted via glomerular filtration. Clinically, it is commonly used at high concentrations with high viscosity and exhibits nephrotoxicity. However, some patients are severely allergic to iodine-based contrast agents, making coronary CT angiography impossible. Gadolinium-based contrast agents, on the other hand, contain highly toxic gadolinium ions, which are paramagnetic and can significantly shorten tissue relaxation time, resulting in high signal enhancement. The incidence of acute allergic reactions and viscosity of gadolinium-based contrast agents are much lower than those of iodine-based contrast agents, with less injection resistance and significantly weaker nephrotoxicity. Clinical trials have shown that gadolinium-based contrast agents can be used as contrast agents. Therefore, in order to solve the above problems, the existing scheme uses gadolinium contrast agent to replace iodine contrast agent to perform coronary CT angiography, which can meet the needs of patients who are allergic to iodine contrast agent.
[0004] However, in existing methods, the dosage of gadolinium contrast agent is determined by the relevant personnel based on subjective experience. This is highly subjective and may result in poor filling effect of gadolinium contrast agent in the coronary artery, thus reducing image quality. Summary of the Invention
[0005] To address the technical problem of low image quality in the background art, embodiments of this application provide an image generation method, an image acquisition method, and related apparatus for improving image quality.
[0006] A first aspect of this application provides an image generation method applied to a control module in a computed tomography (CT) system, the system further including a scanning component and a syringe component, the method comprising: The molar concentration and molality of a specified gadolinium contrast agent are obtained, and a target dose is calculated based on the molar concentration, the molality, and the patient's weight. The target dose is directly proportional to the molality and the patient's weight, and inversely proportional to the molar concentration. Send an injection command including the target dose to the syringe assembly, so that the syringe assembly first injects a preset dose of saline into the patient, and then injects the target dose of the specified gadolinium contrast agent; If the concentration of gadolinium contrast agent in the patient's coronary artery exceeds a preset concentration threshold, a control command is sent to the scanning component so that the scanning component can scan the patient to obtain CT data. The system receives the CT data sent by the scanning component and generates a target image based on the CT data.
[0007] Optionally, before sending an injection command including the target dose to the syringe assembly, causing the syringe assembly to first inject a preset dose of saline into the patient and then inject the target dose of the specified gadolinium contrast agent, the method further includes: The ratio of the viscosity of the specified iodine contrast agent to the viscosity of the specified gadolinium contrast agent at the same temperature is determined as the relative viscosity. Based on the preset relationship between body weight, the contrast agent concentration of the specified iodine contrast agent, and the injection flow rate of the specified iodine contrast agent, the corresponding iodine injection flow rate of the specified iodine contrast agent is obtained according to the patient's body weight and the specified contrast agent concentration of the specified iodine contrast agent. Based on a preset gadolinium injection flow rate algorithm, the corresponding target injection flow rate is calculated according to the iodine injection flow rate and the relative viscosity, wherein the target injection flow rate is proportional to the iodine injection flow rate and the relative viscosity, respectively. Sending an injection command including the target dose to the syringe assembly, such that the syringe assembly first injects a preset dose of saline into the patient, and then injects the target dose of the specified gadolinium contrast agent, includes: An injection command including the target dose and the target injection flow rate is sent to the syringe assembly, such that the syringe assembly first injects a preset dose of saline into the patient, and then injects the target dose of the specified gadolinium contrast agent at the target injection flow rate.
[0008] Optionally, the system further includes electrocardiogram electrodes, and before obtaining the molar concentration and molality of the specified gadolinium contrast agent, the method further includes: After the ECG electrodes are attached to the patient's chest, the system receives multiple ECG data points from multiple predetermined heartbeat cycles based on the ECG acquisition command input by the user. Each ECG data point includes an ECG time point and a corresponding cardiac voltage. Among the plurality of electrocardiogram (ECG) data, the ECG data whose cardiac voltage exceeds a preset voltage threshold and whose corresponding target derivative value is zero is identified as the peak data. The target derivative value is the derivative value obtained by substituting the ECG time point corresponding to the cardiac voltage into the first derivative function of the ECG function with respect to the ECG time point. The ECG function is composed of the plurality of ECG data. Calculate the time interval between the peak data of every two adjacent ECG time points, and determine the patient's target heart rate cycle based on the time interval; Based on a preset algorithm, the corresponding collection time period is obtained by calculating the ECG time point of the latest peak data, the target heart rate cycle, and the preset coefficient range. Sending control commands to the scanning component to cause the scanning component to scan the patient and obtain CT data includes: Control commands are sent to the scanning component so that the scanning component scans the patient during the acquisition period to obtain CT data.
[0009] Optionally, before obtaining the molar concentration and molality of the specified gadolinium contrast agent, the method further includes: Send a scan position determination command to the scanning component so that the scanning component acquires chest images of the patient during the acquisition time period; The acquired chest image is divided according to the division instructions input by the user to obtain the location of the patient's coronary arteries; Based on the preset relationship between the image position and the scanning position of the scanning component, the corresponding target scanning position is determined according to the position of the coronary artery; Sending control commands to the scanning component to cause the scanning component to scan the patient and obtain CT data during the acquisition period includes: A control command is sent to the scanning component so that the scanning component is positioned at the target scanning location during the acquisition period to scan the patient and obtain CT data.
[0010] Optionally, before obtaining the molar concentration and molality of the specified gadolinium contrast agent, the method further includes: A calcium integration determination command is sent to the scanning component so that the scanning component is positioned at the target scanning location during the acquisition time period to scan the patient and obtain a coronary artery image; The patient's calcification score is calculated based on the coronary artery images. Sending control commands to the scanning component to cause the scanning component to be positioned at the target scanning location during the acquisition time period to scan the patient and obtain CT data includes: Based on the preset relationship between the integral and the scanning parameters, the corresponding target scanning parameters are obtained according to the calcification integral, and control commands are sent to the scanning component so that the scanning component is in the target scanning position during the acquisition time period, and CT data is obtained by scanning the patient according to the target scanning parameters.
[0011] A second aspect of this application provides an image acquisition method applied to a control module in a computed tomography (CT) system, the system further including a scanning component and a syringe component, the method comprising: The ratio of the viscosity of the specified iodine contrast agent to the viscosity of the specified gadolinium contrast agent at the same temperature is determined as the relative viscosity. Based on the preset relationship between body weight, the contrast agent concentration of the specified iodine contrast agent, and the injection flow rate of the specified iodine contrast agent, the corresponding iodine injection flow rate of the specified iodine contrast agent is obtained according to the patient's body weight and the specified contrast agent concentration of the specified iodine contrast agent. Based on a preset gadolinium injection flow rate algorithm, the corresponding target injection flow rate is calculated according to the iodine injection flow rate and the relative viscosity, wherein the target injection flow rate is proportional to the iodine injection flow rate and the relative viscosity, respectively. Send an injection command including the target injection flow rate to the syringe assembly, so that the syringe assembly first injects a preset dose of saline into the patient, and then injects the specified gadolinium contrast agent at the target injection flow rate; If the concentration of gadolinium contrast agent in the patient's coronary artery exceeds a preset concentration threshold, a control command is sent to the scanning component so that the scanning component can scan the patient to obtain CT data. The system receives the CT data sent by the scanning component and generates a target image based on the CT data.
[0012] A third aspect of this application provides an image generation apparatus. The computed tomography (CT) system in which the apparatus is located includes a scanning component and a syringe component. The apparatus includes: The first acquisition unit is used to acquire the molar concentration and molality of a specified gadolinium contrast agent, and to calculate the corresponding target dose based on the molar concentration, the molality and the patient's weight. The target dose is directly proportional to the molality and the patient's weight, and inversely proportional to the molar concentration. The first sending unit is configured to send an injection command including the target dose to the syringe assembly, so that the syringe assembly first injects a preset dose of saline into the patient, and then injects the target dose of the specified gadolinium contrast agent. The first sending unit is further configured to send a control command to the scanning component if the concentration of gadolinium contrast agent in the patient's coronary artery exceeds a preset concentration threshold, so that the scanning component can scan the patient to obtain CT data. The first processing unit is used to receive the CT data sent by the scanning component and generate a target image based on the CT data.
[0013] A fourth aspect of this application provides an image acquisition device, in which a computed tomography (CT) system includes a scanning component and a syringe component, the device comprising: The determining unit is used to determine the ratio of the viscosity of the specified iodine contrast agent to the viscosity of the specified gadolinium contrast agent at the same temperature as the relative viscosity, and to obtain the corresponding iodine injection flow rate of the specified iodine contrast agent based on the preset relationship between the patient's body weight, the contrast agent concentration of the specified iodine contrast agent and the injection flow rate of the specified iodine contrast agent, according to the patient's body weight and the specified contrast agent concentration of the specified iodine contrast agent. The calculation unit is used to calculate the corresponding target injection flow rate based on the iodine injection flow rate and the relative viscosity according to the preset gadolinium injection flow rate algorithm, wherein the target injection flow rate is proportional to the iodine injection flow rate and the relative viscosity, respectively. The second sending unit is used to send an injection command including the target injection flow rate to the syringe assembly, so that the syringe assembly first injects a preset dose of saline into the patient, and then injects the specified gadolinium contrast agent at the target injection flow rate. The second sending unit is further configured to send a control command to the scanning component if the concentration of gadolinium contrast agent in the patient's coronary artery exceeds a preset concentration threshold, so that the scanning component can scan the patient to obtain CT data. The second processing unit is used to receive the CT data sent by the scanning component and generate a target image based on the CT data.
[0014] A fifth aspect of this application provides a computer device, comprising: Central processing unit, memory, and input / output interfaces; The memory is either a short-term storage memory or a persistent storage memory; The central processing unit is configured to communicate with the memory and execute instructions in the memory to perform the aforementioned method.
[0015] A sixth aspect of this application provides a computer-readable storage medium including instructions that, when executed on a computer, cause the computer to perform the aforementioned method.
[0016] As can be seen from the above technical solutions, the embodiments of this application have the following advantages: First, the molar concentration and molality of the specified gadolinium contrast agent are obtained. Based on these concentrations and the patient's weight, a target dose is calculated. Then, an injection command including the target dose is sent to the syringe assembly. This causes the syringe assembly to first inject a preset dose of saline solution into the patient, followed by the target dose of the specified gadolinium contrast agent. If the concentration of the gadolinium contrast agent in the patient's coronary arteries exceeds a preset concentration threshold, a control command is sent to the scanning assembly to scan the patient and obtain CT data. Finally, the CT data sent by the scanning assembly is received, and a target image is generated based on this data. The target dose of the gadolinium contrast agent can be calculated based on its molar concentration and molality, combined with the patient's weight, and the target image is generated based on this target dose. Through repeated practice, this method can objectively calculate the target dose, thereby ensuring the filling effect of the gadolinium contrast agent in the coronary arteries and improving image quality.
[0017] Additional aspects and advantages of embodiments of this application will be set forth in part in the description which follows, and in part will be obvious from the description, or may be learned by practice of embodiments of this application. Attached Figure Description
[0018] To more clearly illustrate the technical solutions in the embodiments of this application or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this application. For those skilled in the art, other drawings can be obtained based on the structures shown in these drawings without creative effort.
[0019] Figure 1 This is a schematic diagram of an embodiment of an image generation method disclosed in this application; Figure 2 This is a schematic diagram of another embodiment of an image generation method disclosed in this application; Figure 3 This is a schematic diagram of the iodine contrast agent disclosed in this application; Figure 4 This is a schematic diagram illustrating the relationship between body weight, contrast agent concentration, and injection flow rate disclosed in this application. Figure 5 This is a schematic diagram of the gadolinium contrast agent disclosed in this application; Figure 6 This is a schematic diagram of an embodiment of an image acquisition method disclosed in this application; Figure 7 This is a schematic diagram of an embodiment of an image generation apparatus disclosed in this application; Figure 8 This is a schematic diagram of another embodiment of an image generation apparatus disclosed in this application; Figure 9 This is a schematic diagram of an embodiment of an image acquisition device disclosed in this application; Figure 10 This is a schematic diagram of another embodiment of an image acquisition device disclosed in this application.
[0020] The realization of the objectives, functional features and advantages of the embodiments of this application will be further explained in conjunction with the embodiments and with reference to the accompanying drawings. Detailed Implementation
[0021] To prevent coronary artery disease, it is necessary to understand the specific condition of the coronary arteries in a timely manner. Coronary CT angiography (CCTA) is used as a non-invasive screening technique, combined with iodine contrast agents for imaging to understand the specific situation. However, some patients are severely allergic to iodine contrast agents and cannot undergo CCTA. To address this issue, existing methods use gadolinium contrast agents instead of iodine contrast agents for CCTA, meeting the needs of these patients. However, the clinical application of gadolinium contrast agents in CCTA is relatively limited, and standardized operating procedures have not yet been established. Iodine contrast agent injection parameters cannot be directly copied, so personnel determine the gadolinium contrast agent dosage based on subjective experience. This subjectivity may lead to poor filling effect of the gadolinium contrast agent in the coronary arteries, reducing image quality. To solve the above technical problems, this application provides an image generation method, an image acquisition method, and related devices. Based on the molar concentration and molality of the gadolinium contrast agent, combined with the patient's weight, a target dose of the gadolinium contrast agent can be calculated, and a target image is generated based on the target dose. Through repeated practice, this method can more objectively calculate the target dose, thereby ensuring the filling effect of gadolinium contrast agent in the coronary arteries and improving image quality.
[0022] The embodiments of this application are described in detail below. Examples of the embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals denote the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the accompanying drawings are exemplary and intended to explain the embodiments of this application, and should not be construed as limiting the embodiments of this application. All other embodiments obtained by those skilled in the art based on the embodiments of this application without creative effort are within the protection scope of the embodiments of this application.
[0023] In the description of the embodiments of this application, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "circumferential", "radial", etc., indicating the orientation or positional relationship are based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing the embodiments of this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on the embodiments of this application.
[0024] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. The terms "first," "second," "third," "fourth," etc., are used to distinguish similar objects and are not necessarily used to describe a specific order or sequence. It should be understood that such data can be interchanged where appropriate so that the embodiments described herein can be implemented in orders other than those illustrated or described herein. Furthermore, the terms "comprising" and "having," and any variations thereof, are intended to cover non-exclusive inclusion; for example, a process, method, system, product, or apparatus that includes a series of steps or units is not necessarily limited to those steps or units explicitly listed, but may include other steps or units not explicitly listed or inherent to such processes, methods, products, or apparatus. In the description of embodiments of this application, "a plurality of" means two or more, unless otherwise expressly specified.
[0025] In the embodiments of this application, unless otherwise explicitly specified and limited, the terms "installation," "connection," "linking," "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. For those skilled in the art, the specific meaning of the above terms in the embodiments of this application can be understood according to the specific circumstances.
[0026] In the embodiments of this application, unless otherwise expressly specified and limited, "above" or "below" the second feature can include direct contact between the first and second features, or contact between the first and second features through another feature between them. Furthermore, "above," "over," and "on top" of the second feature includes the first feature being directly above or diagonally above the second feature, or simply indicates that the first feature is at a higher horizontal level than the second feature. "Below," "below," and "under" the second feature includes the first feature being directly below or diagonally below the second feature, or simply indicates that the first feature is at a lower horizontal level than the second feature.
[0027] The following describes one image generation method according to this application. Please refer to... Figure 1 One embodiment of the image generation method of this application is applied to the control module of a computed tomography (CT) system. The system also includes a scanning component and a syringe component. The method includes: 101. Obtain the molar concentration and molality of the specified gadolinium contrast agent, and calculate the corresponding target dose based on the molar concentration, molality and patient weight. The molar concentration and molality of a specified gadolinium contrast agent are obtained. Based on these concentrations and the patient's weight, a target dose is calculated. The target dose is directly proportional to both the molality and patient weight, and inversely proportional to the molar concentration. Various gadolinium contrast agents exist; this is the specified gadolinium contrast agent. Both the molar concentration and molality are preset.
[0028] 102. Send an injection command including the target dose to the syringe assembly so that the syringe assembly first injects a preset dose of normal saline into the patient, and then injects the target dose of the specified gadolinium contrast agent. An injection command, including the target dose, is sent to the syringe assembly, causing it to first inject a preset dose of saline solution into the patient, followed by the target dose of a specified gadolinium contrast agent. Specifically, the syringe assembly can be configured with sensors to monitor in real time whether the injected dose has reached the target dose.
[0029] 103. If the concentration of gadolinium contrast agent in the patient's coronary artery exceeds the preset concentration threshold, a control command is sent to the scanning component so that the scanning component can scan the patient to obtain CT data. If the concentration of gadolinium contrast agent in the patient's coronary arteries exceeds a preset concentration threshold, a control command is sent to the scanning component to scan the patient and obtain CT data. Specifically, the concentration of gadolinium contrast agent in the coronary arteries can be determined through data such as CT values, or it can be monitored based on the injected dose and a preset coronary artery volume; the specific method is not limited here.
[0030] 104. Receive CT data sent by the scanning component and generate target images based on the CT data.
[0031] The system receives CT data from the scanning component and generates a target image based on that data. Specifically, after the scanning component performs a scan, it obtains CT data. Upon receiving the CT data, the control module performs preprocessing and grayscale processing to generate the corresponding target image.
[0032] In this embodiment, the molar concentration and molality of a specified gadolinium contrast agent are first obtained. Based on these concentrations and the patient's weight, a target dose is calculated. Then, an injection command including the target dose is sent to the syringe assembly. This causes the syringe assembly to first inject a preset dose of saline solution into the patient, followed by the target dose of the specified gadolinium contrast agent. If the concentration of the gadolinium contrast agent in the patient's coronary artery exceeds a preset concentration threshold, a control command is sent to the scanning assembly to scan the patient and obtain CT data. Finally, the CT data sent by the scanning assembly is received, and a target image is generated based on the CT data. The target dose of the gadolinium contrast agent can be calculated based on its molar concentration and molality, combined with the patient's weight, and the target image is generated based on this target dose. Through repeated practice, this method can objectively calculate the target dose, thereby ensuring the filling effect of the gadolinium contrast agent in the coronary artery and improving image quality.
[0033] Please see Figures 2 to 5 Another embodiment of the image generation method of this application is applied to the control module of a CT system. The system further includes ECG electrodes, a scanning assembly, and a syringe assembly. The method includes: 201. Obtain the data acquisition time period, target scanning location, and patient's calcification score; The data acquisition time period, target scanning location, and patient's calcification score are obtained. Specifically, this is described in three parts.
[0034] I. Data collection period: After attaching ECG electrodes to the patient's chest, the system receives multiple ECG data points across several predetermined heartbeat cycles based on the user's input ECG acquisition command. Each ECG data point includes an ECG time point and a corresponding cardiac voltage. The predetermined heartbeat cycle is a predicted cycle, which can be the average value of multiple patients. The multiple ECG data points form an ECG, with the horizontal axis representing ECG time and the vertical axis representing cardiac voltage.
[0035] Next, ECG data points whose voltage exceeds a preset voltage threshold and whose corresponding target derivative value is zero are identified as the peak data. The target derivative value is the derivative obtained by substituting the ECG time point corresponding to the ECG voltage into the first derivative of the ECG function with respect to the ECG time point. The ECG function is composed of multiple ECG data points. The preset voltage threshold must be higher than all peaks on the ECG except for the R wave peak. The ECG function is the curve on the ECG. A target derivative value of zero indicates that the data point is an extreme point. Data meeting both conditions is considered the peak data.
[0036] Then, the time interval between the highest data points of each two adjacent ECG time points is calculated, and the patient's target heart rate cycle is determined based on the time interval. Specifically, if there are multiple time intervals, the patient's target heart rate cycle is the average of the multiple time intervals; if there is only one time interval, that time interval is the target heart rate cycle.
[0037] Finally, based on a preset algorithm, the corresponding acquisition time period is calculated according to the ECG time point of the latest acquired peak data, the target heart rate cycle, and a preset coefficient range. Specifically, in one implementation, the acquisition time period = peak ECG time point + target heart rate cycle × preset coefficient range. It is understood that other formula types exist, but they are not limited here. The acquisition time period corresponds to the end of diastole, when the cardiac motion amplitude is relatively small, minimizing its impact on imaging.
[0038] II. Target scanning location: First, a scan position determination command is sent to the scanning component, enabling it to acquire chest images of the patient during the acquisition period. If no specific acquisition position is specified, the scanning component scans the entire chest area of the patient during the acquisition period to obtain chest images.
[0039] Next, based on the user-input segmentation instructions, the acquired chest image is segmented to determine the location of the patient's coronary arteries. This segmentation can be done manually by the user or using a preset algorithm; the specific method is not limited here.
[0040] Finally, based on the preset relationship between the image position and the scanning position of the scanning components, the corresponding target scanning position is determined according to the location of the coronary arteries. The target scanning position is aligned with the coronary artery region to minimize the imaging area and reduce the radiation dose to the patient.
[0041] III. Calcification score: First, a calcium integration determination command is sent to the scanning component so that the scanning component is positioned at the target scanning location during the acquisition period to scan the patient and obtain coronary artery images.
[0042] Finally, the patient's calcification score is calculated based on the coronary artery images. Specifically, there are at least two implementation methods. The first method involves identifying areas on the coronary artery images with CT values greater than or equal to a preset CT threshold and areas greater than or equal to a preset area threshold as calcifications. Then, based on a preset relationship between CT values and weights, the corresponding calcification weight is obtained according to the CT value of the calcification. The product of the calcification weight and the area of the calcification is then determined as the calcification score. Finally, the calcification scores of all calcifications are summed to obtain the patient's calcification score. The second method involves identifying areas on the coronary artery images with CT values greater than or equal to a preset CT threshold as calcifications. The product of the image pixel area, image slice thickness, and voxel size of the calcification is then determined as the calcification score. The calcification scores of all calcifications are then summed to obtain the patient's calcification score. It is understood that other implementation methods exist, but specific methods are not limited here. The calcification score helps to avoid the influence on subsequent imaging.
[0043] 202. Obtain the molar concentration and molality of the specified gadolinium contrast agent, and calculate the corresponding target dose based on the molar concentration, molality and patient weight. The molar concentration and molality of a specified gadolinium contrast agent are obtained, and the corresponding target dose is calculated based on the molar concentration, molality, and patient weight. The target dose is directly proportional to the molality and patient weight, and inversely proportional to the molar concentration. In one embodiment, the corresponding formula is: ;in, For the target dose, The molar concentration of gadolinium contrast agent is usually pre-prepared and fixed. The molar concentration can be selected and entered by the user. For example, specifying gadolinium contrast agent as gadobenzamide, by... Figure 5 Given that the molar concentration is 0.5 mol / L, the mass molar concentration is selected as 0.2 mmol / kg, and the patient's weight is 65 kg, the target dose is 0.5 × 0.2 × 65 = 6.5 mL.
[0044] Besides the formulas mentioned above, there are other formulas that can represent the target dose, which are not specified here.
[0045] 203. The ratio of the viscosity of the specified iodine contrast agent to the viscosity of the specified gadolinium contrast agent at the same temperature is determined as the relative viscosity. Based on the preset relationship between body weight, the contrast agent concentration of the specified iodine contrast agent and the injection flow rate of the specified iodine contrast agent, the corresponding iodine injection flow rate of the specified iodine contrast agent is obtained according to the patient's body weight and the specified contrast agent concentration of the specified iodine contrast agent. The relative viscosity is determined by the ratio of the viscosity of a specified iodine contrast agent to the viscosity of a specified gadolinium contrast agent at the same temperature. Based on a preset relationship between patient weight, the contrast agent concentration of the specified iodine contrast agent, and the injection flow rate of the specified iodine contrast agent, the corresponding iodine injection flow rate of the specified iodine contrast agent is obtained according to the patient's weight and the specified contrast agent concentration. The preset relationship between patient weight, the contrast agent concentration of the specified iodine contrast agent, and the injection flow rate of the specified iodine contrast agent can be set as needed. In one embodiment, it is... Figure 4 The situation is presented as follows. For example, at a temperature of 37°C, the specified iodine contrast agent is iopamidol at 370 mgI / ml, and the specified gadolinium contrast agent is gadobenzamide. Figure 3 It can be seen that the viscosity of the specified iodine contrast agent is 9.4 mPa·s, which is derived from... Figure 5 It can be seen that the specified gadolinium contrast agent viscosity is 5.3 mPa·s, and the relative viscosity is 9.4 / 5.3≈1.77. Figure 4 The iodine injection flow rate is 4.8 ml / s.
[0046] 204. Based on the preset gadolinium injection flow rate algorithm, the corresponding target injection flow rate is calculated according to the iodine injection flow rate and relative viscosity; Based on a preset gadolinium injection flow rate algorithm, the corresponding target injection flow rate is calculated according to the iodine injection flow rate and relative viscosity, wherein the target injection flow rate is proportional to both the iodine injection flow rate and the relative viscosity. In one embodiment, the corresponding formula is: ;in, To specify the target injection flow rate of the gadolinium contrast agent, Relative viscosity, This represents the iodine injection flow rate. It is understood that other formula types exist, but specific examples are not limited here.
[0047] 205. Send an injection command to the syringe assembly, including the target dose and the target injection flow rate, so that the syringe assembly first injects a preset dose of normal saline into the patient, and then injects a target dose of the specified gadolinium contrast agent at the target injection flow rate. An injection command, including a target dose and a target injection flow rate, is sent to the syringe assembly. This causes the syringe assembly to first inject a preset dose of saline into the patient, followed by the injection of a target dose of the specified gadolinium contrast agent at the target injection flow rate. Specifically, saline is injected first, followed by the specified gadolinium contrast agent, in preparation for subsequent imaging.
[0048] 206. If the concentration of gadolinium contrast agent in the patient's coronary artery exceeds the preset concentration threshold, the corresponding target scanning parameters are obtained based on the preset relationship between the integral and the scanning parameters, and a control command is sent to the scanning component so that the scanning component is in the target scanning position during the acquisition time period. The patient is then scanned according to the target scanning parameters to obtain CT data. If the concentration of gadolinium contrast agent in the patient's coronary arteries exceeds a preset concentration threshold, the corresponding target scanning parameters are obtained based on the preset relationship between the integral and the scanning parameters, and a control command is sent to the scanning component to ensure that the scanning component is at the target scanning position during the acquisition time period. The patient is then scanned according to the target scanning parameters to obtain CT data. Specifically, the concentration of gadolinium contrast agent in the coronary arteries is monitored using CT values. If it exceeds a preset concentration threshold, scanning can begin. The target scanning parameters are first adjusted based on the calcium integral, and then, based on these parameters, a scan is performed at the acquisition time period and the target scanning position to obtain CT data.
[0049] 207. Receive CT data sent by the scanning component and generate target images based on the CT data.
[0050] It receives CT data sent by the scanning component and generates the target image based on the CT data. This involves preprocessing and grayscale processing of the CT data, which will not be elaborated here.
[0051] In this embodiment, the target dose of gadolinium contrast agent is calculated based on its molar concentration and molality, combined with the patient's weight. The target image is then generated based on this target dose. Furthermore, the injection flow rate of gadolinium contrast agent can be calculated based on relevant data from iodine contrast agent. Through repeated practice, this method has proven to be a relatively objective way to calculate the target dose, thereby ensuring the filling effect of gadolinium contrast agent in the coronary arteries, improving image quality, and guaranteeing patient safety. Additionally, adjusting scanning parameters based on calcium integration during the acquisition time period and at the target scanning location further enhances image reliability.
[0052] The above describes an image generation method according to an embodiment of this application. The following describes an image acquisition method according to an embodiment of this application. Please refer to... Figure 6 An image acquisition method according to an embodiment of this application is applied to the control module of a CT system. The system also includes a scanning component and a syringe component. The method includes: 601. The ratio of the viscosity of the specified iodine contrast agent to the viscosity of the specified gadolinium contrast agent at the same temperature is determined as the relative viscosity. Based on the preset relationship between body weight, the contrast agent concentration of the specified iodine contrast agent, and the injection flow rate of the specified iodine contrast agent, the corresponding iodine injection flow rate of the specified iodine contrast agent is obtained according to the patient's body weight and the specified contrast agent concentration of the specified iodine contrast agent. The relative viscosity is determined by the ratio of the viscosity of a specified iodine contrast agent to that of a specified gadolinium contrast agent at the same temperature. Based on a preset relationship between patient weight, the contrast agent concentration of the specified iodine contrast agent, and the injection flow rate of the specified iodine contrast agent, the corresponding iodine injection flow rate of the specified iodine contrast agent is obtained according to the patient's weight and the specified contrast agent concentration. Viscosity data can be obtained by searching a database, while the specified contrast agent concentration refers to the contrast agent concentration of the corresponding specified iodine contrast agent already prepared in the current syringe assembly, which can be preset.
[0053] 602. Based on the preset gadolinium injection flow rate algorithm, the corresponding target injection flow rate is calculated according to the iodine injection flow rate and relative viscosity; Based on a preset gadolinium injection flow rate algorithm, the corresponding target injection flow rate is calculated according to the iodine injection flow rate and relative viscosity, wherein the target injection flow rate is proportional to both the iodine injection flow rate and the relative viscosity. In one embodiment, the product of the iodine injection flow rate and the relative viscosity is the target injection flow rate.
[0054] 603. Send an injection command including a target injection flow rate to the syringe assembly so that the syringe assembly first injects a preset dose of normal saline into the patient, and then injects a specified gadolinium contrast agent at the target injection flow rate. An injection command, including a target injection flow rate, is sent to the syringe assembly, causing it to first inject a preset dose of saline into the patient, followed by the injection of a specified gadolinium contrast agent at the target flow rate. Specifically, the injection flow rate of the syringe assembly can be adjusted based on sensors and the injection tube opening.
[0055] 604. If the concentration of gadolinium contrast agent in the patient's coronary artery exceeds the preset concentration threshold, a control command is sent to the scanning component so that the scanning component can scan the patient to obtain CT data. If the concentration of gadolinium contrast agent in the patient's coronary arteries exceeds a preset concentration threshold, a control command is sent to the scanning component to scan the patient and obtain CT data. Specifically, the concentration of gadolinium contrast agent in the coronary arteries can be determined through data such as CT values, or it can be monitored based on the injected dose and a preset coronary artery volume; the specific method is not limited here.
[0056] 605. Receive CT data sent by the scanning component and generate a target image based on the CT data.
[0057] The system receives CT data from the scanning component and generates a target image based on that data. Specifically, after the scanning component performs a scan, it obtains CT data. Upon receiving the CT data, the control module performs preprocessing and grayscale processing to generate the corresponding target image.
[0058] In this embodiment, the ratio of the viscosity of a specified iodine contrast agent to that of a specified gadolinium contrast agent at the same temperature is first determined as the relative viscosity. Based on a preset relationship between body weight, the concentration of the specified iodine contrast agent, and the injection flow rate of the specified iodine contrast agent, the corresponding iodine injection flow rate of the specified iodine contrast agent is obtained according to the patient's body weight and the specified concentration of the specified iodine contrast agent. Then, based on a preset gadolinium injection flow rate algorithm, the corresponding target injection flow rate is calculated according to the iodine injection flow rate and the relative viscosity. An injection command including the target injection flow rate is then sent to the syringe assembly, causing the syringe assembly to first inject a preset dose of saline into the patient, and then inject the specified gadolinium contrast agent at the target injection flow rate. If the concentration of gadolinium contrast agent in the patient's coronary artery exceeds a preset concentration threshold, a control command is sent to the scanning assembly, causing the scanning assembly to scan the patient and obtain CT data. Finally, the CT data sent by the scanning assembly is received, and a target image is generated based on the CT data. This application can objectively calculate the target injection flow rate in practice, ensuring patient safety and improving reliability.
[0059] The following is a detailed description of an image generation apparatus according to an embodiment of this application. Please refer to... Figure 7 One embodiment of the image generation apparatus of this application is provided. The CT system in which the apparatus is located includes a scanning component and a syringe component. The apparatus includes: The first acquisition unit 701 is used to acquire the molar concentration and molality of a specified gadolinium contrast agent, and to calculate the corresponding target dose based on the molar concentration, molality and patient weight. The target dose is directly proportional to the molality and patient weight, and inversely proportional to the molar concentration. The first sending unit 702 is used to send an injection command including a target dose to the syringe assembly, so that the syringe assembly first injects a preset dose of saline into the patient, and then injects a target dose of a specified gadolinium contrast agent. The first transmitting unit 702 is also used to send a control command to the scanning component if the concentration of gadolinium contrast agent in the patient's coronary artery exceeds a preset concentration threshold, so that the scanning component can scan the patient to obtain CT data. The first processing unit 703 is used to receive CT data sent by the scanning component and generate a target image based on the CT data.
[0060] In this embodiment, the first acquisition unit 701 first acquires the molar concentration and molality of the specified gadolinium contrast agent, and calculates the corresponding target dose based on the molar concentration, molality, and patient weight. Then, the first sending unit 702 sends an injection command including the target dose to the syringe assembly, causing the syringe assembly to first inject a preset dose of saline solution into the patient, followed by the target dose of the specified gadolinium contrast agent. If the concentration of the gadolinium contrast agent in the patient's coronary artery exceeds a preset concentration threshold, a control command is sent to the scanning assembly, causing the scanning assembly to scan the patient and obtain CT data. Finally, the first processing unit 703 receives the CT data sent by the scanning assembly and generates a target image based on the CT data. The target dose of the gadolinium contrast agent can be calculated based on its molar concentration and molality, combined with the patient's weight, and the target image is generated based on this target dose. Through repeated practice, this method can objectively calculate the target dose, thereby ensuring the filling effect of the gadolinium contrast agent in the coronary artery and improving image quality.
[0061] Figure 8 This is a schematic diagram of an image generation device provided in an embodiment of this application. The image generation device 800 may include one or more central processing units (CPUs) 801 and a memory 805, in which one or more application programs or data are stored.
[0062] The memory 805 can be volatile or persistent storage. The program stored in the memory 805 can include one or more modules, each module including a series of instruction operations on the image generating apparatus 800. Furthermore, the central processing unit 801 can be configured to communicate with the memory 805 and execute the series of instruction operations in the memory 805 on the image generating apparatus 800.
[0063] The image generation device 800 may also include one or more power supplies 802, one or more wired or wireless network interfaces 803, one or more input / output interfaces 804, and / or one or more operating systems, such as Windows Server™, Mac OS X™, Unix™, Linux™, FreeBSD™, etc.
[0064] The central processing unit 801 can perform the aforementioned... Figures 1 to 5 The specific operations performed by the image generation device in the illustrated embodiment will not be described in detail here.
[0065] Please see Figure 9One embodiment of the image acquisition device of this application is provided. The CT system in which the device is located includes a scanning component and a syringe component. The device includes: The determining unit 901 is used to determine the ratio of the viscosity of the specified iodine contrast agent to the viscosity of the specified gadolinium contrast agent at the same temperature as the relative viscosity, and based on the preset relationship between body weight, the contrast agent concentration of the specified iodine contrast agent and the injection flow rate of the specified iodine contrast agent, the corresponding iodine injection flow rate of the specified iodine contrast agent is obtained according to the patient's body weight and the specified contrast agent concentration of the specified iodine contrast agent. The calculation unit 902 is used to calculate the corresponding target injection flow rate based on the preset gadolinium injection flow rate algorithm, according to the iodine injection flow rate and the relative viscosity, wherein the target injection flow rate is proportional to the iodine injection flow rate and the relative viscosity, respectively. The second sending unit 903 is used to send an injection command including a target injection flow rate to the syringe assembly, so that the syringe assembly first injects a preset dose of saline into the patient, and then injects a specified gadolinium contrast agent at the target injection flow rate. The second sending unit 903 is also used to send a control command to the scanning component if the concentration of gadolinium contrast agent in the patient's coronary artery exceeds a preset concentration threshold, so that the scanning component can scan the patient to obtain CT data. The second processing unit 904 is used to receive CT data sent by the scanning component and generate a target image based on the CT data.
[0066] In this embodiment, the determining unit 901 first determines the ratio of the viscosity of the specified iodine contrast agent to the viscosity of the specified gadolinium contrast agent at the same temperature as the relative viscosity. Based on the preset relationship between body weight, the contrast agent concentration of the specified iodine contrast agent, and the injection flow rate of the specified iodine contrast agent, the iodine injection flow rate of the specified iodine contrast agent is obtained according to the patient's body weight and the specified contrast agent concentration of the specified iodine contrast agent. Then, the calculation unit 902 calculates the corresponding target injection flow rate based on the preset gadolinium injection flow rate algorithm, according to the iodine injection flow rate and the relative viscosity. Then, the second sending unit 903 sends an injection command including the target injection flow rate to the syringe assembly, so that the syringe assembly first injects a preset dose of saline into the patient, and then injects the specified gadolinium contrast agent at the target injection flow rate. If the concentration of gadolinium contrast agent in the patient's coronary artery exceeds a preset concentration threshold, a control command is sent to the scanning assembly, so that the scanning assembly scans the patient to obtain CT data. Finally, the second processing unit 904 receives the CT data sent by the scanning assembly and generates a target image based on the CT data. This application can objectively calculate the target injection flow rate based on practical experience, ensuring patient safety and improving reliability.
[0067] Figure 10This is a schematic diagram of an image acquisition device provided in an embodiment of this application. The image acquisition device 1000 may include one or more central processing units (CPUs) 1001 and a memory 1005, in which one or more applications or data are stored.
[0068] The memory 1005 can be volatile or persistent storage. The program stored in the memory 1005 can include one or more modules, each module including a series of instruction operations on the image acquisition device 1000. Furthermore, the central processing unit 1001 can be configured to communicate with the memory 1005 and execute the series of instruction operations stored in the memory 1005 on the image acquisition device 1000.
[0069] The image acquisition device 1000 may also include one or more power supplies 1002, one or more wired or wireless network interfaces 1003, one or more input / output interfaces 1004, and / or one or more operating systems, such as Windows Server™, Mac OS X™, Unix™, Linux™, FreeBSD™, etc.
[0070] The central processing unit 1001 can perform the aforementioned... Figures 2 to 6 The specific operations performed by the image acquisition device in the illustrated embodiment will not be described in detail here.
[0071] This application also provides a computer-readable storage medium including instructions that, when executed on a computer, cause the computer to perform the methods described in the foregoing embodiments.
[0072] Those skilled in the art will clearly understand that, for the sake of convenience and brevity, the specific working processes of the systems, devices, and units described above can be referred to the corresponding processes in the foregoing method embodiments, and will not be repeated here.
[0073] It should be noted that although the steps in the flowcharts of the various embodiments are drawn sequentially according to the arrows, unless explicitly stated herein, there is no strict order restriction on the execution of these steps, and they can be executed in other orders. Moreover, at least some steps in the flowcharts of the various embodiments may include multiple steps or multiple stages. These steps or stages are not necessarily completed at the same time, but can be executed at different times. The execution order of these steps or stages is not necessarily sequential, but can be performed alternately or in turn with other steps or at least some of the steps or stages in other steps.
[0074] In the description of this specification, the references to terms such as "one embodiment," "some embodiments," "example," "specific example," or "some examples," etc., refer to specific features, structures, materials, or characteristics described in connection with that embodiment or example, which are included in at least one embodiment or example of the embodiments of this application. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples. Moreover, without contradiction, those skilled in the art can combine and integrate the different embodiments or examples described in this specification, as well as the features of different embodiments or examples.
[0075] If the integrated unit is implemented as a software functional unit and sold or used as an independent product, it can be stored in a computer-readable storage medium. Based on this understanding, the technical solution of this application, in essence, or the part that contributes to the prior art, or all or part of the technical solution, can be embodied in the form of a software product. This computer software product is stored in a storage medium and includes several instructions to cause a computer device (which may be a personal computer, server, or network device, etc.) to execute all or part of the steps of the methods of the various embodiments of this application. The aforementioned storage medium includes various media capable of storing program code, such as USB flash drives, portable hard drives, read-only memory (ROM), random access memory (RAM), magnetic disks, or optical disks.
[0076] The above are merely preferred embodiments of the present application and do not limit the patent scope of the present application. Any equivalent structural transformations made using the description and drawings of the present application under the inventive concept of the present application, or direct / indirect applications in other related technical fields, are included within the patent protection scope of the present application.
Claims
1. An image generation method, characterized in that, A control module for use in a computed tomography (CT) system, the system further comprising a scanning assembly and a syringe assembly, the method comprising: The molar concentration and molality of a specified gadolinium contrast agent are obtained, and a target dose is calculated based on the molar concentration, the molality, and the patient's weight. The target dose is directly proportional to the molality and the patient's weight, and inversely proportional to the molar concentration. Send an injection command including the target dose to the syringe assembly, so that the syringe assembly first injects a preset dose of saline into the patient, and then injects the target dose of the specified gadolinium contrast agent; If the concentration of gadolinium contrast agent in the patient's coronary artery exceeds a preset concentration threshold, a control command is sent to the scanning component so that the scanning component can scan the patient to obtain CT data. The system receives the CT data sent by the scanning component and generates a target image based on the CT data.
2. The image generation method according to claim 1, characterized in that, Before sending an injection command including the target dose to the syringe assembly, such that the syringe assembly first injects a preset dose of saline into the patient and then injects the target dose of the specified gadolinium contrast agent, the method further includes: The ratio of the viscosity of the specified iodine contrast agent to the viscosity of the specified gadolinium contrast agent at the same temperature is determined as the relative viscosity. Based on the preset relationship between body weight, the contrast agent concentration of the specified iodine contrast agent, and the injection flow rate of the specified iodine contrast agent, the corresponding iodine injection flow rate of the specified iodine contrast agent is obtained according to the patient's body weight and the specified contrast agent concentration of the specified iodine contrast agent. Based on a preset gadolinium injection flow rate algorithm, the corresponding target injection flow rate is calculated according to the iodine injection flow rate and the relative viscosity, wherein the target injection flow rate is proportional to the iodine injection flow rate and the relative viscosity, respectively. Sending an injection command including the target dose to the syringe assembly, such that the syringe assembly first injects a preset dose of saline into the patient, and then injects the target dose of the specified gadolinium contrast agent, includes: An injection command including the target dose and the target injection flow rate is sent to the syringe assembly, such that the syringe assembly first injects a preset dose of saline into the patient, and then injects the target dose of the specified gadolinium contrast agent at the target injection flow rate.
3. The image generation method according to claim 1, characterized in that, The system further includes electrocardiogram electrodes, and before obtaining the molar concentration and molality of the specified gadolinium contrast agent, the method further includes: After the ECG electrodes are attached to the patient's chest, the system receives multiple ECG data points from multiple predetermined heartbeat cycles based on the ECG acquisition command input by the user. Each ECG data point includes an ECG time point and a corresponding cardiac voltage. Among the plurality of electrocardiogram (ECG) data, the ECG data whose cardiac voltage exceeds a preset voltage threshold and whose corresponding target derivative value is zero is identified as the peak data. The target derivative value is the derivative value obtained by substituting the ECG time point corresponding to the cardiac voltage into the first derivative function of the ECG function with respect to the ECG time point. The ECG function is composed of the plurality of ECG data. Calculate the time interval between the peak data of every two adjacent ECG time points, and determine the patient's target heart rate cycle based on the time interval; Based on a preset algorithm, the corresponding collection time period is obtained by calculating the ECG time point of the latest peak data, the target heart rate cycle, and the preset coefficient range. Sending control commands to the scanning component to cause the scanning component to scan the patient and obtain CT data includes: Control commands are sent to the scanning component so that the scanning component scans the patient during the acquisition period to obtain CT data.
4. The image generation method according to claim 3, characterized in that, Before obtaining the molar concentration and molality of the specified gadolinium contrast agent, the method further includes: Send a scan position determination command to the scanning component so that the scanning component acquires chest images of the patient during the acquisition time period; The acquired chest image is divided according to the division instructions input by the user to obtain the location of the patient's coronary arteries; Based on the preset relationship between the image position and the scanning position of the scanning component, the corresponding target scanning position is determined according to the position of the coronary artery; Sending control commands to the scanning component to cause the scanning component to scan the patient and obtain CT data during the acquisition period includes: A control command is sent to the scanning component so that the scanning component is positioned at the target scanning location during the acquisition period to scan the patient and obtain CT data.
5. The image generation method according to claim 4, characterized in that, Before obtaining the molar concentration and molality of the specified gadolinium contrast agent, the method further includes: A calcium integration determination command is sent to the scanning component so that the scanning component is positioned at the target scanning location during the acquisition time period to scan the patient and obtain a coronary artery image; The patient's calcification score is calculated based on the coronary artery images. Sending control commands to the scanning component to cause the scanning component to be positioned at the target scanning location during the acquisition time period to scan the patient and obtain CT data includes: Based on the preset relationship between the integral and the scanning parameters, the corresponding target scanning parameters are obtained according to the calcification integral, and control commands are sent to the scanning component so that the scanning component is in the target scanning position during the acquisition time period, and CT data is obtained by scanning the patient according to the target scanning parameters.
6. An image acquisition method, characterized in that, A control module for use in a computed tomography (CT) system, the system further comprising a scanning assembly and a syringe assembly, the method comprising: The ratio of the viscosity of the specified iodine contrast agent to the viscosity of the specified gadolinium contrast agent at the same temperature is determined as the relative viscosity. Based on the preset relationship between body weight, the contrast agent concentration of the specified iodine contrast agent, and the injection flow rate of the specified iodine contrast agent, the corresponding iodine injection flow rate of the specified iodine contrast agent is obtained according to the patient's body weight and the specified contrast agent concentration of the specified iodine contrast agent. Based on a preset gadolinium injection flow rate algorithm, the corresponding target injection flow rate is calculated according to the iodine injection flow rate and the relative viscosity, wherein the target injection flow rate is proportional to the iodine injection flow rate and the relative viscosity, respectively. Send an injection command including the target injection flow rate to the syringe assembly, so that the syringe assembly first injects a preset dose of saline into the patient, and then injects the specified gadolinium contrast agent at the target injection flow rate; If the concentration of gadolinium contrast agent in the patient's coronary artery exceeds a preset concentration threshold, a control command is sent to the scanning component so that the scanning component can scan the patient to obtain CT data. The system receives the CT data sent by the scanning component and generates a target image based on the CT data.
7. An image generation apparatus, characterized in that, The computed tomography (CT) system in which the device is located includes a scanning assembly and a syringe assembly. The device includes: The first acquisition unit is used to acquire the molar concentration and molality of a specified gadolinium contrast agent, and to calculate the corresponding target dose based on the molar concentration, the molality and the patient's weight. The target dose is directly proportional to the molality and the patient's weight, and inversely proportional to the molar concentration. The first sending unit is configured to send an injection command including the target dose to the syringe assembly, so that the syringe assembly first injects a preset dose of saline into the patient, and then injects the target dose of the specified gadolinium contrast agent. The first sending unit is further configured to send a control command to the scanning component if the concentration of gadolinium contrast agent in the patient's coronary artery exceeds a preset concentration threshold, so that the scanning component can scan the patient to obtain CT data. The first processing unit is used to receive the CT data sent by the scanning component and generate a target image based on the CT data.
8. An image acquisition device, characterized in that, The computed tomography (CT) system in which the device is located includes a scanning assembly and a syringe assembly. The device includes: The determining unit is used to determine the ratio of the viscosity of the specified iodine contrast agent to the viscosity of the specified gadolinium contrast agent at the same temperature as the relative viscosity, and to obtain the corresponding iodine injection flow rate of the specified iodine contrast agent based on the preset relationship between the patient's body weight, the contrast agent concentration of the specified iodine contrast agent and the injection flow rate of the specified iodine contrast agent, according to the patient's body weight and the specified contrast agent concentration of the specified iodine contrast agent. The calculation unit is used to calculate the corresponding target injection flow rate based on the iodine injection flow rate and the relative viscosity according to the preset gadolinium injection flow rate algorithm, wherein the target injection flow rate is proportional to the iodine injection flow rate and the relative viscosity, respectively. The second sending unit is used to send an injection command including the target injection flow rate to the syringe assembly, so that the syringe assembly first injects a preset dose of saline into the patient, and then injects the specified gadolinium contrast agent at the target injection flow rate. The second sending unit is further configured to send a control command to the scanning component if the concentration of gadolinium contrast agent in the patient's coronary artery exceeds a preset concentration threshold, so that the scanning component can scan the patient to obtain CT data. The second processing unit is used to receive the CT data sent by the scanning component and generate a target image based on the CT data.
9. A computer device, characterized in that, include: Central processing unit, memory, and input / output interfaces; The memory is either a short-term storage memory or a persistent storage memory; The central processing unit is configured to communicate with the memory and execute instructions in the memory to perform the method according to any one of claims 1 to 6.
10. A computer-readable storage medium, characterized in that, Includes instructions that, when executed on a computer, cause the computer to perform the method as described in any one of claims 1 to 6.