Schiff base compound as well as preparation method and application thereof

By preparing Schiff base compound fluorescent probes, the problem of simultaneous and rapid detection of copper and iron ions in existing technologies has been solved, achieving visible color changes and high-sensitivity detection under sunlight, making it suitable for portable detection applications.

CN122404264APending Publication Date: 2026-07-17WUYI UNIV
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Patent Information

Application Number
CN202610587375.5
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2026-04-29
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Existing technologies cannot simultaneously detect copper and iron ions quickly and visually, and most fluorescent probes are only visible under ultraviolet light, lacking a detection method that allows for color changes to be discerned with the naked eye under sunlight.

Method used

A Schiff base compound was developed to prepare a fluorescent probe by reacting 2-furanoylhydrazide with 4-dimethylaminocinnamaldehyde. Using dimethylamino as an auxochrome, a dual-response quenching recognition of Cu2+ and Fe3+ was achieved, exhibiting a clear color change under fluorescent light. The probe was then combined with a portable test strip and kit for detection.

Benefits of technology

It enables rapid and visual detection of Cu2+ and Fe3+, with high sensitivity and selectivity. Color changes can be observed with the naked eye under sunlight, meeting the needs of portable detection.

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Abstract

The invention belongs to the technical field of analysis and detection, and particularly relates to a Schiff base compound as well as a preparation method and application thereof. The Schiff base compound disclosed by the invention is a Schiff base fluorescent probe with a 2-furohydrazide parent nucleus, and can recognize Cu < 2 + > and Fe < 3 + > in a double-response quenching manner; obvious naked eye color change is shown under a fluorescent lamp, fluorescence quenching is shown under a 365 nm ultraviolet lamp, and a simple, convenient and reliable new method is provided for rapid visual detection of double ions.
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